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The map label for this gene is ppnK [H]

Identifier: 158333968

GI number: 158333968

Start: 761023

End: 761955

Strand: Direct

Name: ppnK [H]

Synonym: AM1_0782

Alternate gene names: 158333968

Gene position: 761023-761955 (Clockwise)

Preceding gene: 158333967

Following gene: 158333969

Centisome position: 11.7

GC content: 50.7

Gene sequence:

>933_bases
GTGCAGTTACAGCAAGTCATCATCGTCTATAAAGCTGGGGATACCCATAGCCAACGATGGGCAGAGAAATGTGCCCGTCA
GTTAGAAGCCCAGGGCTGCCATATCTTGATGGGACCCAGTGGTCCAAAAGATAATCCCTATCCGGTTTTTCTAGCCTCTG
CCACACAGGCCATTGACCTCGCTATTGTGCTGGGCGGAGATGGAACGGCTCTAGCCGCTGCTCGACATTTGGCTCCCGAT
GGGATTCCGATTTTGGCGGTCAATATTGGAGGGCATTTAGGATTCCTGACTGAACCCGCCGATCTATTTATGGATACGGA
ACAGGTATGGCAAAGAATTCTTGAAGATCGCTACGCCGTTCAACAGCGAATGATGCTACGAGCCCGCGTCGCCGATCGCG
ATGTTGATCCAACGGATATCCCGGAAGAAGAACCGTTTTACACCGCCCTCAATGAAATGTGTATCAAGCCCGCTTCTGCT
GATCGCATGATTACTTCAATTCTAGAGTTAGAAATTGATGGCGAAGTGGTGGATCAGTATCAAGGCGATGGATTATTAGT
TGCTACACCTACGGGTTCCACCTGCTATACCGTCGCGGCTAGCGGACCGATTTTGCATCCGGGCATGGAAGCTATGGCGA
TCACGCCAATTTGCCCCTTGAGTTTATCCAGTCGGCCCATTGTATTGCCGCCAGGATCACGGGTGAGTGTCTGGCCCCTT
GCGGATCGGGAACTGGCGACCAAGTTATGGATGGATGGGGTCCTGTGTACTTCAATTTGGCCGGGACAGCGAGTGGATAT
CTGGATGGCCAAATACCGGGCCAGGTTTGTATTACTGCGGGAAAATTATTCGTACTATCGCACTCTACGGGAGAAATTAG
ACTGGGCAGGTGCACGAATACAGTACAATAACAATCATCGCATTACAAATTGA

Upstream 100 bases:

>100_bases
ACCCCTCACCTATCAGAATCTACCCCCCACTCATAAAGCGCTGCGAACAGGGTACGGTGATTACATACGCCTGAGCAAAG
CAGAAAAGGGGACCAATCGG

Downstream 100 bases:

>100_bases
TATATATCTCATAAGAATTTAATATGGATTTATTTAGACCGTTACTTTTAGTCATAATTCTTTTCTTCCTAACGGTGGTC
ATGTGTGCATTAGGTAGCCT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 2 [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MQLQQVIIVYKAGDTHSQRWAEKCARQLEAQGCHILMGPSGPKDNPYPVFLASATQAIDLAIVLGGDGTALAAARHLAPD
GIPILAVNIGGHLGFLTEPADLFMDTEQVWQRILEDRYAVQQRMMLRARVADRDVDPTDIPEEEPFYTALNEMCIKPASA
DRMITSILELEIDGEVVDQYQGDGLLVATPTGSTCYTVAASGPILHPGMEAMAITPICPLSLSSRPIVLPPGSRVSVWPL
ADRELATKLWMDGVLCTSIWPGQRVDIWMAKYRARFVLLRENYSYYRTLREKLDWAGARIQYNNNHRITN

Sequences:

>Translated_310_residues
MQLQQVIIVYKAGDTHSQRWAEKCARQLEAQGCHILMGPSGPKDNPYPVFLASATQAIDLAIVLGGDGTALAAARHLAPD
GIPILAVNIGGHLGFLTEPADLFMDTEQVWQRILEDRYAVQQRMMLRARVADRDVDPTDIPEEEPFYTALNEMCIKPASA
DRMITSILELEIDGEVVDQYQGDGLLVATPTGSTCYTVAASGPILHPGMEAMAITPICPLSLSSRPIVLPPGSRVSVWPL
ADRELATKLWMDGVLCTSIWPGQRVDIWMAKYRARFVLLRENYSYYRTLREKLDWAGARIQYNNNHRITN
>Mature_310_residues
MQLQQVIIVYKAGDTHSQRWAEKCARQLEAQGCHILMGPSGPKDNPYPVFLASATQAIDLAIVLGGDGTALAAARHLAPD
GIPILAVNIGGHLGFLTEPADLFMDTEQVWQRILEDRYAVQQRMMLRARVADRDVDPTDIPEEEPFYTALNEMCIKPASA
DRMITSILELEIDGEVVDQYQGDGLLVATPTGSTCYTVAASGPILHPGMEAMAITPICPLSLSSRPIVLPPGSRVSVWPL
ADRELATKLWMDGVLCTSIWPGQRVDIWMAKYRARFVLLRENYSYYRTLREKLDWAGARIQYNNNHRITN

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=262, Percent_Identity=31.6793893129771, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1788968, Length=247, Percent_Identity=35.2226720647773, Blast_Score=134, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6320794, Length=254, Percent_Identity=31.1023622047244, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325068, Length=179, Percent_Identity=32.9608938547486, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322509, Length=196, Percent_Identity=34.1836734693878, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573830, Length=254, Percent_Identity=31.8897637795276, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573828, Length=254, Percent_Identity=31.1023622047244, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573832, Length=254, Percent_Identity=31.8897637795276, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI161077047, Length=254, Percent_Identity=31.8897637795276, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573826, Length=254, Percent_Identity=31.1023622047244, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=28.0575539568345, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=28.0575539568345, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=28.0575539568345, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653424, Length=278, Percent_Identity=28.0575539568345, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281363321, Length=278, Percent_Identity=28.0575539568345, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 34448; Mature: 34448

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLQQVIIVYKAGDTHSQRWAEKCARQLEAQGCHILMGPSGPKDNPYPVFLASATQAIDL
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCEEEE
AIVLGGDGTALAAARHLAPDGIPILAVNIGGHLGFLTEPADLFMDTEQVWQRILEDRYAV
EEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
QQRMMLRARVADRDVDPTDIPEEEPFYTALNEMCIKPASADRMITSILELEIDGEVVDQY
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEEECCHHHHHC
QGDGLLVATPTGSTCYTVAASGPILHPGMEAMAITPICPLSLSSRPIVLPPGSRVSVWPL
CCCEEEEECCCCCEEEEEECCCCEECCCCCCEEECCCCCCCCCCCCEEECCCCCEEEEEC
ADRELATKLWMDGVLCTSIWPGQRVDIWMAKYRARFVLLRENYSYYRTLREKLDWAGARI
CCHHHHHHHHHCCEEEECCCCCCCEEHHEEEHEEEEEEEECCCHHHHHHHHHHCCCCCEE
QYNNNHRITN
EECCCCCCCC
>Mature Secondary Structure
MQLQQVIIVYKAGDTHSQRWAEKCARQLEAQGCHILMGPSGPKDNPYPVFLASATQAIDL
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCEEEE
AIVLGGDGTALAAARHLAPDGIPILAVNIGGHLGFLTEPADLFMDTEQVWQRILEDRYAV
EEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
QQRMMLRARVADRDVDPTDIPEEEPFYTALNEMCIKPASADRMITSILELEIDGEVVDQY
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEEECCHHHHHC
QGDGLLVATPTGSTCYTVAASGPILHPGMEAMAITPICPLSLSSRPIVLPPGSRVSVWPL
CCCEEEEECCCCCEEEEEECCCCEECCCCCCEEECCCCCCCCCCCCEEECCCCCEEEEEC
ADRELATKLWMDGVLCTSIWPGQRVDIWMAKYRARFVLLRENYSYYRTLREKLDWAGARI
CCHHHHHHHHHCCEEEECCCCCCCEEHHEEEHEEEEEEEECCCHHHHHHHHHHCCCCCEE
QYNNNHRITN
EECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]