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The map label for this gene is 158333858

Identifier: 158333858

GI number: 158333858

Start: 654532

End: 656202

Strand: Direct

Name: 158333858

Synonym: AM1_0668

Alternate gene names: NA

Gene position: 654532-656202 (Clockwise)

Preceding gene: 158333857

Following gene: 158333860

Centisome position: 10.06

GC content: 50.27

Gene sequence:

>1671_bases
GTGATTGTTACCCTCATCGTTTTCTTGGGATGGATTGTCTCTGTTTGTCTGCACGAATTTGGACATGCCATTATTGCTTA
CTGGGGAGGAGATAAAACGGTCAAAGATAAGGGTTATCTCACCCTGAACCCGCTCAAATATACGGATGTTTCTTTGAGTT
TGGTACTGCCGATTGTCTTTCTACTGATTGGCGGCATCCCATTGCCTGGAGGAGCAGTCTATATCAATCGCAGCCTGATT
CGGAATCGTTGGTGGGATAGTGCCATGTCCGCAGCAGGCCCTGCGGCAACGTTTATGGTGGCGCTGGTATTGTCGGTGCC
TTTTAGGCTAGGGAATCCCCTTGAGGCGGTGGAAACTTCCCTGAGTTTAGGAACGTTTGAATTAGAGACTCTGACCACCC
AAGATCAACTCTGGTTAGCCCTGGCATTTTTAGGGATGTTAGAAGTTGCGGGCGCTGTTTTAAATTTGCTACCTGTACCT
TCTCTGGACGGCTTTGGGATTATTGAGCCCTGGCTTCCTCCACCGCTGCAACAACAAGTGAGGAAGTATAGCCGTTACGG
GTTTTTAGTTTTATTTGGCTTGCTGTGGTTTGTCCCTGCTGCCAATGCTGCTTTTTGGGGATTGGTCTATGGCTTGAGTC
AGCAGCTCGGCATCCCCGTATTGTTCTCCAGAATGGGGTACTTGGTATTTCGCCAGTGGTCCTGGCTACCGCTGGTGATT
CTGGTAGTGACGATTGCTATTGGTCAACGACTGAACCCTCGAGCCCAGGTGCGGTCTAATCAACGAGTGGATTTGCAGCG
TGCGATCGCAAATGCAGAATCAGCCGTTCAAGCCAATCCCAACCAGCCTCAATATTGGTATCAAAAAGGGCAACTACTCC
TCGCTGATCACCAGTATGAAGCTGCTGAGGCCGCCTTCCATCAGGCCATTCAACTTAAGCCAGATGCGGATACCTGGCAT
TCCCGGGGGATTGCTCTGTTATTTATGCAGCAATACGAACATGCGATCGCAGCCTTTGACGAAACCCTGCATTTGCAGTC
TGATCAATCCCTAGCTTGGGTGCATCGAGGCCGGGCTCAGCGGGGACTACAGCGCTATGAAGATGAAATTACCGACTATG
AGCAGGCCCTCGCTCTCGATCCTGAAAATGCGAATATTTGGTGCGATCACGGTTTAGCCCACTATCACCTGGGCCAATAT
AAAGCAGCGATTGATAGCTTTGATCGAGCCGCCTACATTGATCCATCCTCTTGGACCGCATGGTACTTAAAAGGACTCGC
ACTGATGCCCCAGCAGCAGTTTGAGCGAGCCATTCGCTGCTACGATCATGCCTTAAATCTGCGGGCAGATGCGACCCAGA
CCTGGATTGCTAAAGGTTCAGCCTTGCTACAACTCCAAGATTTTGAAGGGGCGATTGCATCCTATGATCAAGCCCTTTCC
TTAGAGCCTGAGAATGCCACAGCTGTCTATAACAAGGCCTGTACCTATAGTTTGCAAGGGCAACGTGAGAAGGCCTTAGA
GATGCTGAGTCAGGCTCTTAATCTCGATCCAAAAGTCAGTGACCTGGCAGCCTCCGATGTAGACCTCGATCCATTGCGCT
CAGAACCCGCATTTCAGCAGTTGATGGCGGGTTACCATTCCAATTCTGATGGAGCCATGATCTCCGGTTAG

Upstream 100 bases:

>100_bases
CTACATTGGCCGTTCCGACTCTATTATTGATAACCAGTGCATTGACCTATGGCACTTTTACAATATTTGCTAGCTGACCG
ACAGGAATGAAACCGCCGTT

Downstream 100 bases:

>100_bases
GTTAGCCCAATGGGGTGACGATAAAAATGGTGATTAAAGGGATATGGCACTCATGGCTAGGGACAACACAAGAGTTTTTG
GCGCTGATATAAACCAAAGA

Product: M50 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MIVTLIVFLGWIVSVCLHEFGHAIIAYWGGDKTVKDKGYLTLNPLKYTDVSLSLVLPIVFLLIGGIPLPGGAVYINRSLI
RNRWWDSAMSAAGPAATFMVALVLSVPFRLGNPLEAVETSLSLGTFELETLTTQDQLWLALAFLGMLEVAGAVLNLLPVP
SLDGFGIIEPWLPPPLQQQVRKYSRYGFLVLFGLLWFVPAANAAFWGLVYGLSQQLGIPVLFSRMGYLVFRQWSWLPLVI
LVVTIAIGQRLNPRAQVRSNQRVDLQRAIANAESAVQANPNQPQYWYQKGQLLLADHQYEAAEAAFHQAIQLKPDADTWH
SRGIALLFMQQYEHAIAAFDETLHLQSDQSLAWVHRGRAQRGLQRYEDEITDYEQALALDPENANIWCDHGLAHYHLGQY
KAAIDSFDRAAYIDPSSWTAWYLKGLALMPQQQFERAIRCYDHALNLRADATQTWIAKGSALLQLQDFEGAIASYDQALS
LEPENATAVYNKACTYSLQGQREKALEMLSQALNLDPKVSDLAASDVDLDPLRSEPAFQQLMAGYHSNSDGAMISG

Sequences:

>Translated_556_residues
MIVTLIVFLGWIVSVCLHEFGHAIIAYWGGDKTVKDKGYLTLNPLKYTDVSLSLVLPIVFLLIGGIPLPGGAVYINRSLI
RNRWWDSAMSAAGPAATFMVALVLSVPFRLGNPLEAVETSLSLGTFELETLTTQDQLWLALAFLGMLEVAGAVLNLLPVP
SLDGFGIIEPWLPPPLQQQVRKYSRYGFLVLFGLLWFVPAANAAFWGLVYGLSQQLGIPVLFSRMGYLVFRQWSWLPLVI
LVVTIAIGQRLNPRAQVRSNQRVDLQRAIANAESAVQANPNQPQYWYQKGQLLLADHQYEAAEAAFHQAIQLKPDADTWH
SRGIALLFMQQYEHAIAAFDETLHLQSDQSLAWVHRGRAQRGLQRYEDEITDYEQALALDPENANIWCDHGLAHYHLGQY
KAAIDSFDRAAYIDPSSWTAWYLKGLALMPQQQFERAIRCYDHALNLRADATQTWIAKGSALLQLQDFEGAIASYDQALS
LEPENATAVYNKACTYSLQGQREKALEMLSQALNLDPKVSDLAASDVDLDPLRSEPAFQQLMAGYHSNSDGAMISG
>Mature_556_residues
MIVTLIVFLGWIVSVCLHEFGHAIIAYWGGDKTVKDKGYLTLNPLKYTDVSLSLVLPIVFLLIGGIPLPGGAVYINRSLI
RNRWWDSAMSAAGPAATFMVALVLSVPFRLGNPLEAVETSLSLGTFELETLTTQDQLWLALAFLGMLEVAGAVLNLLPVP
SLDGFGIIEPWLPPPLQQQVRKYSRYGFLVLFGLLWFVPAANAAFWGLVYGLSQQLGIPVLFSRMGYLVFRQWSWLPLVI
LVVTIAIGQRLNPRAQVRSNQRVDLQRAIANAESAVQANPNQPQYWYQKGQLLLADHQYEAAEAAFHQAIQLKPDADTWH
SRGIALLFMQQYEHAIAAFDETLHLQSDQSLAWVHRGRAQRGLQRYEDEITDYEQALALDPENANIWCDHGLAHYHLGQY
KAAIDSFDRAAYIDPSSWTAWYLKGLALMPQQQFERAIRCYDHALNLRADATQTWIAKGSALLQLQDFEGAIASYDQALS
LEPENATAVYNKACTYSLQGQREKALEMLSQALNLDPKVSDLAASDVDLDPLRSEPAFQQLMAGYHSNSDGAMISG

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI224809432, Length=222, Percent_Identity=26.5765765765766, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI54607135, Length=258, Percent_Identity=25.5813953488372, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI170784867, Length=224, Percent_Identity=23.2142857142857, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=255, Percent_Identity=26.2745098039216, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=255, Percent_Identity=26.2745098039216, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319387, Length=202, Percent_Identity=27.7227722772277, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17647755, Length=259, Percent_Identity=25.8687258687259, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24585827, Length=259, Percent_Identity=25.8687258687259, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24585829, Length=259, Percent_Identity=25.8687258687259, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24656717, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI18110006, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 61950; Mature: 61950

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTLIVFLGWIVSVCLHEFGHAIIAYWGGDKTVKDKGYLTLNPLKYTDVSLSLVLPIVF
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCEEECCCEECCCHHHHHHHHHH
LLIGGIPLPGGAVYINRSLIRNRWWDSAMSAAGPAATFMVALVLSVPFRLGNPLEAVETS
HHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
LSLGTFELETLTTQDQLWLALAFLGMLEVAGAVLNLLPVPSLDGFGIIEPWLPPPLQQQV
HCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
RKYSRYGFLVLFGLLWFVPAANAAFWGLVYGLSQQLGIPVLFSRMGYLVFRQWSWLPLVI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
LVVTIAIGQRLNPRAQVRSNQRVDLQRAIANAESAVQANPNQPQYWYQKGQLLLADHQYE
HHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCHHHHHCCCCCCCHHHHHCCCEEEECCCHH
AAEAAFHQAIQLKPDADTWHSRGIALLFMQQYEHAIAAFDETLHLQSDQSLAWVHRGRAQ
HHHHHHHHHHCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
RGLQRYEDEITDYEQALALDPENANIWCDHGLAHYHLGQYKAAIDSFDRAAYIDPSSWTA
HHHHHHHHHHHHHHHHHEECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCHHH
WYLKGLALMPQQQFERAIRCYDHALNLRADATQTWIAKGSALLQLQDFEGAIASYDQALS
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEECCCCHHHCCCHHEE
LEPENATAVYNKACTYSLQGQREKALEMLSQALNLDPKVSDLAASDVDLDPLRSEPAFQQ
CCCCCCHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHHH
LMAGYHSNSDGAMISG
HHHHCCCCCCCCEECC
>Mature Secondary Structure
MIVTLIVFLGWIVSVCLHEFGHAIIAYWGGDKTVKDKGYLTLNPLKYTDVSLSLVLPIVF
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCCCCEEECCCEECCCHHHHHHHHHH
LLIGGIPLPGGAVYINRSLIRNRWWDSAMSAAGPAATFMVALVLSVPFRLGNPLEAVETS
HHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
LSLGTFELETLTTQDQLWLALAFLGMLEVAGAVLNLLPVPSLDGFGIIEPWLPPPLQQQV
HCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
RKYSRYGFLVLFGLLWFVPAANAAFWGLVYGLSQQLGIPVLFSRMGYLVFRQWSWLPLVI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
LVVTIAIGQRLNPRAQVRSNQRVDLQRAIANAESAVQANPNQPQYWYQKGQLLLADHQYE
HHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCHHHHHCCCCCCCHHHHHCCCEEEECCCHH
AAEAAFHQAIQLKPDADTWHSRGIALLFMQQYEHAIAAFDETLHLQSDQSLAWVHRGRAQ
HHHHHHHHHHCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
RGLQRYEDEITDYEQALALDPENANIWCDHGLAHYHLGQYKAAIDSFDRAAYIDPSSWTA
HHHHHHHHHHHHHHHHHEECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCHHH
WYLKGLALMPQQQFERAIRCYDHALNLRADATQTWIAKGSALLQLQDFEGAIASYDQALS
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEECCCCHHHCCCHHEE
LEPENATAVYNKACTYSLQGQREKALEMLSQALNLDPKVSDLAASDVDLDPLRSEPAFQQ
CCCCCCHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHHH
LMAGYHSNSDGAMISG
HHHHCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]