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The map label for this gene is infC

Identifier: 158333810

GI number: 158333810

Start: 606916

End: 607449

Strand: Reverse

Name: infC

Synonym: AM1_0619

Alternate gene names: 158333810

Gene position: 607449-606916 (Counterclockwise)

Preceding gene: 158333812

Following gene: 158333807

Centisome position: 9.34

GC content: 46.25

Gene sequence:

>534_bases
GTGGCTCCAATCAAAAAAAGAAATCAACAAAACCAGCCAAATATTAACGAACGCATTCGTTTTCCAAAAATCCGCGTAGT
CGATGCAGATGGAACTCAGCTCGGCATTATGGCGCCTAGCGAAGCAATGGAAATCGCTGATGAGCGGAACCTGGATTTGG
TGTTAGTGAGTGATAAAGCCGATCCACCGGTTTGCCGGGTCATGGACTACGGTAAGTTCAAGTTTGAACAAGAGAAGAAA
GCCCGGGAAGCAAAGAAAAAGCAGCATACTTCTGATGTTAAAGAAGTAAAAATGCGCTACAAGATTCAAACCCATGACTA
CGAAGTGCGGGTTAACCACGCCAAGCGGTTTCTAAAATCTGGCGATAAGGTAAAGGCGACCGTCACTTTCAGAGGCCGGG
AGATTCAGCATTCCCATTTAGCCGAAGCGCTGCTAAAGAAAATGGCGAACGACTTGCTTGATTTTGCCGAGATCCAGCAA
GCACCCAAGCGCGAAGGACGCAATATGATTATGTACCTATCTCCGAAGAAATAG

Upstream 100 bases:

>100_bases
TAAGAGAATGCTGATTCTAATCTGGATCTGTTAGTTTGAAAGGGGTATTCGTTTTCCCTTATTTCTTTCGCTATCTTAAT
TAACAGTAAATTAAACGCCT

Downstream 100 bases:

>100_bases
GACTGGCCTAGCTCCTTCCCTAGCAACCACTTTCAAGCTATAAGGGTGCCCCTCCGACTTGTACCCATTCGTGTAATTCG
TATTCCACACAATGGTTCAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MAPIKKRNQQNQPNINERIRFPKIRVVDADGTQLGIMAPSEAMEIADERNLDLVLVSDKADPPVCRVMDYGKFKFEQEKK
AREAKKKQHTSDVKEVKMRYKIQTHDYEVRVNHAKRFLKSGDKVKATVTFRGREIQHSHLAEALLKKMANDLLDFAEIQQ
APKREGRNMIMYLSPKK

Sequences:

>Translated_177_residues
MAPIKKRNQQNQPNINERIRFPKIRVVDADGTQLGIMAPSEAMEIADERNLDLVLVSDKADPPVCRVMDYGKFKFEQEKK
AREAKKKQHTSDVKEVKMRYKIQTHDYEVRVNHAKRFLKSGDKVKATVTFRGREIQHSHLAEALLKKMANDLLDFAEIQQ
APKREGRNMIMYLSPKK
>Mature_176_residues
APIKKRNQQNQPNINERIRFPKIRVVDADGTQLGIMAPSEAMEIADERNLDLVLVSDKADPPVCRVMDYGKFKFEQEKKA
REAKKKQHTSDVKEVKMRYKIQTHDYEVRVNHAKRFLKSGDKVKATVTFRGREIQHSHLAEALLKKMANDLLDFAEIQQA
PKREGRNMIMYLSPKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:
GO:0003743: Translation initiation factor IF-3
GO:0006412: Translation initiation factor IF-3
GO:0006413: Translation initiation factor IF-3
GO:0005737: Translation initiation factor IF-3

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=174, Percent_Identity=46.551724137931, Blast_Score=140, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_ACAM1 (B0CD77)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001514982.1
- ProteinModelPortal:   B0CD77
- SMR:   B0CD77
- GeneID:   5679447
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_0619
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- BioCyc:   AMAR329726:AM1_0619-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20560; Mature: 20429

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPIKKRNQQNQPNINERIRFPKIRVVDADGTQLGIMAPSEAMEIADERNLDLVLVSDKA
CCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCEEEEECCHHHHHHHCCCCCEEEEEECCC
DPPVCRVMDYGKFKFEQEKKAREAKKKQHTSDVKEVKMRYKIQTHDYEVRVNHAKRFLKS
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEHHHHHHHHC
GDKVKATVTFRGREIQHSHLAEALLKKMANDLLDFAEIQQAPKREGRNMIMYLSPKK
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure 
APIKKRNQQNQPNINERIRFPKIRVVDADGTQLGIMAPSEAMEIADERNLDLVLVSDKA
CCCCCCCCCCCCCHHHHCCCCEEEEEECCCCEEEEECCHHHHHHHCCCCCEEEEEECCC
DPPVCRVMDYGKFKFEQEKKAREAKKKQHTSDVKEVKMRYKIQTHDYEVRVNHAKRFLKS
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEHHHHHHHHC
GDKVKATVTFRGREIQHSHLAEALLKKMANDLLDFAEIQQAPKREGRNMIMYLSPKK
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA