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The map label for this gene is argC

Identifier: 158333801

GI number: 158333801

Start: 600281

End: 601339

Strand: Direct

Name: argC

Synonym: AM1_0609

Alternate gene names: 158333801

Gene position: 600281-601339 (Clockwise)

Preceding gene: 158333798

Following gene: 158333802

Centisome position: 9.23

GC content: 50.52

Gene sequence:

>1059_bases
ATGGGTTCTCAGGAAGATATTCCTGTTGGCATTATTGGAGCGTCTGGATATGGCGGGGTCCAACTGACTCGCCTACTGTT
GGAACATCCCCATGTCCATCTGGCCTATTTAGGGGGCGATAGCAGTGCGGGGCGTCCATTTGCAGACTTGTATCCCCACT
TGGGGTTTAAACAAGACTTAAAAGTAGAAGCCATCGATTTAGACAAAGTTGTTGAGCGGACCCAGGTGGTCTTTTTGGCT
CTTCCCAATGGTTTGGCCGCAGAGATGGCACCGACTTTGGTGGAATGCGGTTGCAAAGTCTTGGATCTCTCTGCCGATTA
TCGATTTACAAACCTGGACACCTATGAAGATTGGTACGGGACGAAACGACAAGATCGTGATTTGGCCTCTACAGCAGTCT
ATGGTTTGCCCGAACTCTATCGACAGGGAATTTCAACGGCTAGCTTAGTGGGCTGTCCAGGGTGCTTCCCCACCGCTAGT
TTGTTGGCTTTAGCCCCCTTGCTCAAACAAGGTTTAATTGACCCGAACAGTGCCATTATTGATGCCAAAACCGGCACCTC
TGGCGGAGGACGCCAAGCTAAAACCCATCTGCTCCTTGCTGAGGCTAATGGCAGTATTGGTCCTTATGGCGTCGCCCACC
ATCGTCATACCCCTGAAATTGAACAGGTAAGTAGTGATTTGGCAGGGCGAGAGGTGGTTGTCCAGTTTACGCCTCATTTA
GCACCCATGACCCGTGGGATTTTGGCCACGGTTTATGCCACGATGCGAGACCCTGGGCTAGTGAGAGAAGATTTGATTAC
GATCTTTAGCGCCTTTTATCGGAACTCACCTTGGGTCAAGGTCTTACCGGGCAGTACCTATCCCTTTACGAAATGGGCCT
ATGGCACAAACCTTTGCTACCTCGGCATAGAAGTGGATCAGCGGACCGGTCGCGTTATCGTGATTTCTGCCATTGATAAT
TTGATGAAGGGTCAGGCGGGGCAAGCAGTCCAATGCTTGAACTTGATGATGGGTTGGCCAGAAACCATGGGATTGCCGGA
ACTAACCTTTTACCCCTAA

Upstream 100 bases:

>100_bases
GATATCAATAAAAGTGGTGATCGATATCATCATCGTTATTTTTGGGAAGCCTGAACTACATTAACTGTTTGTATGACTGA
CCTCTGAGGAAAAAATGAAT

Downstream 100 bases:

>100_bases
GGGAACCGTATTGGGGGAAAATAAAAGAGTTACAAATTCTCTAAGTAGATGGCTACAAATCATAAAAATAGGCTGGTGTG
GGCGGTGTGGACCATCGTCA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MGSQEDIPVGIIGASGYGGVQLTRLLLEHPHVHLAYLGGDSSAGRPFADLYPHLGFKQDLKVEAIDLDKVVERTQVVFLA
LPNGLAAEMAPTLVECGCKVLDLSADYRFTNLDTYEDWYGTKRQDRDLASTAVYGLPELYRQGISTASLVGCPGCFPTAS
LLALAPLLKQGLIDPNSAIIDAKTGTSGGGRQAKTHLLLAEANGSIGPYGVAHHRHTPEIEQVSSDLAGREVVVQFTPHL
APMTRGILATVYATMRDPGLVREDLITIFSAFYRNSPWVKVLPGSTYPFTKWAYGTNLCYLGIEVDQRTGRVIVISAIDN
LMKGQAGQAVQCLNLMMGWPETMGLPELTFYP

Sequences:

>Translated_352_residues
MGSQEDIPVGIIGASGYGGVQLTRLLLEHPHVHLAYLGGDSSAGRPFADLYPHLGFKQDLKVEAIDLDKVVERTQVVFLA
LPNGLAAEMAPTLVECGCKVLDLSADYRFTNLDTYEDWYGTKRQDRDLASTAVYGLPELYRQGISTASLVGCPGCFPTAS
LLALAPLLKQGLIDPNSAIIDAKTGTSGGGRQAKTHLLLAEANGSIGPYGVAHHRHTPEIEQVSSDLAGREVVVQFTPHL
APMTRGILATVYATMRDPGLVREDLITIFSAFYRNSPWVKVLPGSTYPFTKWAYGTNLCYLGIEVDQRTGRVIVISAIDN
LMKGQAGQAVQCLNLMMGWPETMGLPELTFYP
>Mature_351_residues
GSQEDIPVGIIGASGYGGVQLTRLLLEHPHVHLAYLGGDSSAGRPFADLYPHLGFKQDLKVEAIDLDKVVERTQVVFLAL
PNGLAAEMAPTLVECGCKVLDLSADYRFTNLDTYEDWYGTKRQDRDLASTAVYGLPELYRQGISTASLVGCPGCFPTASL
LALAPLLKQGLIDPNSAIIDAKTGTSGGGRQAKTHLLLAEANGSIGPYGVAHHRHTPEIEQVSSDLAGREVVVQFTPHLA
PMTRGILATVYATMRDPGLVREDLITIFSAFYRNSPWVKVLPGSTYPFTKWAYGTNLCYLGIEVDQRTGRVIVISAIDNL
MKGQAGQAVQCLNLMMGWPETMGLPELTFYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:
GO:0003942: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0005488: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0005737: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0006520: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0006526: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0008652: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0016491: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0016620: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0046983: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0051287: N-acetyl-gamma-glutamyl-phosphate reductase
GO:0055114: N-acetyl-gamma-glutamyl-phosphate reductase

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=340, Percent_Identity=36.1764705882353, Blast_Score=194, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6320913, Length=347, Percent_Identity=30.835734870317, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_ACAM1 (B0CD68)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001514973.1
- ProteinModelPortal:   B0CD68
- SMR:   B0CD68
- GeneID:   5679437
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_0609
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- ProtClustDB:   PRK00436
- BioCyc:   AMAR329726:AM1_0609-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38109; Mature: 37978

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSQEDIPVGIIGASGYGGVQLTRLLLEHPHVHLAYLGGDSSAGRPFADLYPHLGFKQDL
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCC
KVEAIDLDKVVERTQVVFLALPNGLAAEMAPTLVECGCKVLDLSADYRFTNLDTYEDWYG
EEEEECHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCEECCCCCHHHHCC
TKRQDRDLASTAVYGLPELYRQGISTASLVGCPGCFPTASLLALAPLLKQGLIDPNSAII
CCCCCHHHHHHHHHCCHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
DAKTGTSGGGRQAKTHLLLAEANGSIGPYGVAHHRHTPEIEQVSSDLAGREVVVQFTPHL
ECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCH
APMTRGILATVYATMRDPGLVREDLITIFSAFYRNSPWVKVLPGSTYPFTKWAYGTNLCY
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCEEE
LGIEVDQRTGRVIVISAIDNLMKGQAGQAVQCLNLMMGWPETMGLPELTFYP
EEEEEECCCCCEEEEEHHHHHHCCCCCCHHHHHHHHHCCCHHCCCCCEECCC
>Mature Secondary Structure 
GSQEDIPVGIIGASGYGGVQLTRLLLEHPHVHLAYLGGDSSAGRPFADLYPHLGFKQDL
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCC
KVEAIDLDKVVERTQVVFLALPNGLAAEMAPTLVECGCKVLDLSADYRFTNLDTYEDWYG
EEEEECHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCEECCCCCHHHHCC
TKRQDRDLASTAVYGLPELYRQGISTASLVGCPGCFPTASLLALAPLLKQGLIDPNSAII
CCCCCHHHHHHHHHCCHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
DAKTGTSGGGRQAKTHLLLAEANGSIGPYGVAHHRHTPEIEQVSSDLAGREVVVQFTPHL
ECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCH
APMTRGILATVYATMRDPGLVREDLITIFSAFYRNSPWVKVLPGSTYPFTKWAYGTNLCY
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCEEE
LGIEVDQRTGRVIVISAIDNLMKGQAGQAVQCLNLMMGWPETMGLPELTFYP
EEEEEECCCCCEEEEEHHHHHHCCCCCCHHHHHHHHHCCCHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA