Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 158333723

GI number: 158333723

Start: 505378

End: 505902

Strand: Reverse

Name: pgsA [H]

Synonym: AM1_0529

Alternate gene names: 158333723

Gene position: 505902-505378 (Counterclockwise)

Preceding gene: 158333724

Following gene: 158333722

Centisome position: 7.78

GC content: 45.71

Gene sequence:

>525_bases
ATGACCCTTGCCACTTGGATCACGATTTCCCGATTGTTTGCTCTACCCTTTTTGCTCTATGGTTTACAGGACGGTATTGC
GGAGAATTTCTCTGCCCGCTGGATTTGTTTAGCCATCTTTATTGTGGCTGCTAGCACTGACTGGTTAGATGGTTATCTGG
CCCGTAAATTCGATCAAGTGACCGATCTGGGAAAATTCCTCGATCCCCTTGTAGATAAGTTACTGATTTTGGGCCCCTTA
ATTGCACTAGTCGAATTAGGCCAGATCCCTGCTTGGAGTGTGGTGATTATTCTGACTCGAGAGTTAGCCATTGCTGGATG
GCGCGTCCAGCAAACCCAAATTTCAGGAGCCAATTGGTGGGGCAAAGTTAAAACTGTTCTGCAGATTATTGCCGTCTCTT
TCTTAATTGCACCTTTGTCAGGGGTGTGGGTACCCGTTTCCTTAGGAATTTATGCCGCATCGATATGCCTAACAGTCGTT
TCTGGCATTGTATATATACTGCCTCAATCACCTTCTGTCCAATAA

Upstream 100 bases:

>100_bases
GAGTTACGACATTAATGAACAACTACGGGTGCGAAGTGCTATCAGTACTGATGGAGAAGCTGTTGGCATTCTCGAATATC
GCATTCGTTTTTGACACCCT

Downstream 100 bases:

>100_bases
CGAGGGGTGTTATGAAGGAGAAAAATTTCCACAAAGATCTTGGATTAAAAGTTAATAATATTTTAATTTTATCGTAATTT
CAGTATTTCCCGTAGCACCT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTLATWITISRLFALPFLLYGLQDGIAENFSARWICLAIFIVAASTDWLDGYLARKFDQVTDLGKFLDPLVDKLLILGPL
IALVELGQIPAWSVVIILTRELAIAGWRVQQTQISGANWWGKVKTVLQIIAVSFLIAPLSGVWVPVSLGIYAASICLTVV
SGIVYILPQSPSVQ

Sequences:

>Translated_174_residues
MTLATWITISRLFALPFLLYGLQDGIAENFSARWICLAIFIVAASTDWLDGYLARKFDQVTDLGKFLDPLVDKLLILGPL
IALVELGQIPAWSVVIILTRELAIAGWRVQQTQISGANWWGKVKTVLQIIAVSFLIAPLSGVWVPVSLGIYAASICLTVV
SGIVYILPQSPSVQ
>Mature_173_residues
TLATWITISRLFALPFLLYGLQDGIAENFSARWICLAIFIVAASTDWLDGYLARKFDQVTDLGKFLDPLVDKLLILGPLI
ALVELGQIPAWSVVIILTRELAIAGWRVQQTQISGANWWGKVKTVLQIIAVSFLIAPLSGVWVPVSLGIYAASICLTVVS
GIVYILPQSPSVQ

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=138, Percent_Identity=32.6086956521739, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 19040; Mature: 18909

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLATWITISRLFALPFLLYGLQDGIAENFSARWICLAIFIVAASTDWLDGYLARKFDQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TDLGKFLDPLVDKLLILGPLIALVELGQIPAWSVVIILTRELAIAGWRVQQTQISGANWW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEHEECCCCCHH
GKVKTVLQIIAVSFLIAPLSGVWVPVSLGIYAASICLTVVSGIVYILPQSPSVQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure 
TLATWITISRLFALPFLLYGLQDGIAENFSARWICLAIFIVAASTDWLDGYLARKFDQV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TDLGKFLDPLVDKLLILGPLIALVELGQIPAWSVVIILTRELAIAGWRVQQTQISGANWW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEHEECCCCCHH
GKVKTVLQIIAVSFLIAPLSGVWVPVSLGIYAASICLTVVSGIVYILPQSPSVQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]