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The map label for this gene is yrbG [H]

Identifier: 158333561

GI number: 158333561

Start: 327689

End: 328786

Strand: Reverse

Name: yrbG [H]

Synonym: AM1_0360

Alternate gene names: 158333561

Gene position: 328786-327689 (Counterclockwise)

Preceding gene: 158333562

Following gene: 158333558

Centisome position: 5.06

GC content: 47.09

Gene sequence:

>1098_bases
ATGATCGTAACGGCTATCGCTGCTATTGTTGGCGGTTTAGTGCTGTTAGTTGTTGGGGCGGAAGCCTTAGTTCGAGGTGC
GTCTCGCTTAGCAACGATGGTGGGTCTGTCTCCGTTGATCATTGGCCTAACTATTGTGGCCTATGGCACCAGCGCGCCTG
AAATGGCCGTTAGTGTCAAATCCAGCATCATTGGCCAAGGTGACATCTCCTTGGGAAATGTGATTGGCAGTAATATCTTT
AATATTCTGCTGATCCTAGGTCTTTCATCTCTAATTACCCCACTATTGGTAGCCCAGCAGTTGGTCCGTCTAGATGTCCC
CATTATGATTGGGGTCTCCGGCTTGATGTGGCTTTTTAGCTGGGATGGCAACCTGGGGCGGTCGGATGGCGTGATCTTAT
GTCTAGGCGGGATTATCTACACCCTCTTTTTGATTTATCAAGGTCGGCGAGAACATAACGAAGAAGTTCAAGCGGAATAT
GCCAATGAATACGGTAAGCCGATCCAGTTCTCAGGACCCAGCTTATTGGCCAATCTAGGGTATGTCGTAGTGGGCGCGAT
TTTACTCGTGTCAGGCTCCAATTCCTTGGTAAATGGTTCAGTTAGCATTGCTCAGAGATTCGGGATTTCTGAACTCGTTA
TTGGTTTAACCATTATTTCAGTGGGGACGTCTTTGCCTGAGTTAGCCACGTCCATTGTGGCGAGTTTTCGAGGAGAGCGA
GATATTGCCGTTGGTAATGTGATTGGCAGTAATATTTTCAATATTTTAACGGCCTTAGGATTGGCTAGTATGCTTGCTCC
AGGTGGTATCGCCGTGACCAACACGGTTCGCTCCTTTGATATCCCCATTATGATTGCTGCAGCAGTGGCCTGTCTTCCCA
TTTTTGCCACGGGCAATGTGATTTCTCGGTGGGAAGGAATCTTATTTTTGATCTATTACATGGCCTATAACAGCTATCTG
GTATTGGATACCATGCACCATGAGGGCATTAGCGTATTGACCACCGTTATCAGTACGTTTATCGCTCCGTTGACGATTAT
TACCTTTGCGATTATTACCTTCCGAACGGTTCGACACCAGCGAAGCAAAAAAGTCTAG

Upstream 100 bases:

>100_bases
ATTGACTTAGAGAAGAGGGGACTCAGCTATCTCGTGCATTCTGATTTCGCTACAATCGCGATTATGTGTGCAACTTTGCC
ATCTTATCTAGGGAACAACC

Downstream 100 bases:

>100_bases
GGTTAATGCCTATTGCTGCGGGTTGGCAGAGAGCTGAGCAAAGCCAGCTTTCAGCAATAATTCTTGGCCCTGGTTGCTGA
GCAAGAGTTGAGTGTAGGCT

Product: K+-dependent Na+/Ca+ exchanger

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MIVTAIAAIVGGLVLLVVGAEALVRGASRLATMVGLSPLIIGLTIVAYGTSAPEMAVSVKSSIIGQGDISLGNVIGSNIF
NILLILGLSSLITPLLVAQQLVRLDVPIMIGVSGLMWLFSWDGNLGRSDGVILCLGGIIYTLFLIYQGRREHNEEVQAEY
ANEYGKPIQFSGPSLLANLGYVVVGAILLVSGSNSLVNGSVSIAQRFGISELVIGLTIISVGTSLPELATSIVASFRGER
DIAVGNVIGSNIFNILTALGLASMLAPGGIAVTNTVRSFDIPIMIAAAVACLPIFATGNVISRWEGILFLIYYMAYNSYL
VLDTMHHEGISVLTTVISTFIAPLTIITFAIITFRTVRHQRSKKV

Sequences:

>Translated_365_residues
MIVTAIAAIVGGLVLLVVGAEALVRGASRLATMVGLSPLIIGLTIVAYGTSAPEMAVSVKSSIIGQGDISLGNVIGSNIF
NILLILGLSSLITPLLVAQQLVRLDVPIMIGVSGLMWLFSWDGNLGRSDGVILCLGGIIYTLFLIYQGRREHNEEVQAEY
ANEYGKPIQFSGPSLLANLGYVVVGAILLVSGSNSLVNGSVSIAQRFGISELVIGLTIISVGTSLPELATSIVASFRGER
DIAVGNVIGSNIFNILTALGLASMLAPGGIAVTNTVRSFDIPIMIAAAVACLPIFATGNVISRWEGILFLIYYMAYNSYL
VLDTMHHEGISVLTTVISTFIAPLTIITFAIITFRTVRHQRSKKV
>Mature_365_residues
MIVTAIAAIVGGLVLLVVGAEALVRGASRLATMVGLSPLIIGLTIVAYGTSAPEMAVSVKSSIIGQGDISLGNVIGSNIF
NILLILGLSSLITPLLVAQQLVRLDVPIMIGVSGLMWLFSWDGNLGRSDGVILCLGGIIYTLFLIYQGRREHNEEVQAEY
ANEYGKPIQFSGPSLLANLGYVVVGAILLVSGSNSLVNGSVSIAQRFGISELVIGLTIISVGTSLPELATSIVASFRGER
DIAVGNVIGSNIFNILTALGLASMLAPGGIAVTNTVRSFDIPIMIAAAVACLPIFATGNVISRWEGILFLIYYMAYNSYL
VLDTMHHEGISVLTTVISTFIAPLTIITFAIITFRTVRHQRSKKV

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=280, Percent_Identity=38.5714285714286, Blast_Score=147, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 38477; Mature: 38477

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTAIAAIVGGLVLLVVGAEALVRGASRLATMVGLSPLIIGLTIVAYGTSAPEMAVSVK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
SSIIGQGDISLGNVIGSNIFNILLILGLSSLITPLLVAQQLVRLDVPIMIGVSGLMWLFS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEE
WDGNLGRSDGVILCLGGIIYTLFLIYQGRREHNEEVQAEYANEYGKPIQFSGPSLLANLG
CCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCCCCEEECCHHHHHHHH
YVVVGAILLVSGSNSLVNGSVSIAQRFGISELVIGLTIISVGTSLPELATSIVASFRGER
HHHHHHHHHCCCCCCEECCHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
DIAVGNVIGSNIFNILTALGLASMLAPGGIAVTNTVRSFDIPIMIAAAVACLPIFATGNV
CEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHCCCH
ISRWEGILFLIYYMAYNSYLVLDTMHHEGISVLTTVISTFIAPLTIITFAIITFRTVRHQ
HHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSKKV
HHCCC
>Mature Secondary Structure
MIVTAIAAIVGGLVLLVVGAEALVRGASRLATMVGLSPLIIGLTIVAYGTSAPEMAVSVK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
SSIIGQGDISLGNVIGSNIFNILLILGLSSLITPLLVAQQLVRLDVPIMIGVSGLMWLFS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEE
WDGNLGRSDGVILCLGGIIYTLFLIYQGRREHNEEVQAEYANEYGKPIQFSGPSLLANLG
CCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCCCCEEECCHHHHHHHH
YVVVGAILLVSGSNSLVNGSVSIAQRFGISELVIGLTIISVGTSLPELATSIVASFRGER
HHHHHHHHHCCCCCCEECCHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
DIAVGNVIGSNIFNILTALGLASMLAPGGIAVTNTVRSFDIPIMIAAAVACLPIFATGNV
CEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHCCCH
ISRWEGILFLIYYMAYNSYLVLDTMHHEGISVLTTVISTFIAPLTIITFAIITFRTVRHQ
HHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSKKV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]