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The map label for this gene is aphA [H]

Identifier: 158333515

GI number: 158333515

Start: 286670

End: 288244

Strand: Reverse

Name: aphA [H]

Synonym: AM1_0287

Alternate gene names: 158333515

Gene position: 288244-286670 (Counterclockwise)

Preceding gene: 158333520

Following gene: 158333514

Centisome position: 4.43

GC content: 46.98

Gene sequence:

>1575_bases
ATGAAGCAAGTGATGATTCGTGAGCCTTTAGTCACTCAGCCAGATACTTCTGTAGCAGATGCGGTGGCAATTTTATATCA
AGCGGAAGCCAACTACTTAGTGGTGGTTGAAGATCAAATTCCTGTGGGGGTGGTTTGCGATCGCACCCTAGTAACCACCC
TAGCCACCCAACTTGATTTGTCCATCACCCCCGTCCAATCCGTAATGGCTCCGCTACCGACCTTGCCTTTAGAACAGGCC
GACGACTTACCCGCCGTTACCCAAGTCATGCAAACCGAAGGTAGTTCCTTTGTTGCCATTGTCGATGAAGCTTCCCATCT
CCAAGGACTGATCACATCAGATACCTTAATCCAGCAATCCTCAGCCTCCACGCCTTCCGATAATGTCGTTTCACTTCAAA
AGCGAATCAAGGAATTAGAGAATCAGGTCAGTGATCGCCAATTATTAGAAGCCAAGCTAAGAAGTTCTGAAGGCAAAATC
CGAGCAGTATTTGAAGCGATGAAGGACTTGGTCTTTGTTTGTGATGTGGATAAAGGTGAAATTAGCAATATCGAAGTGGC
TCCCACGAATTCTAGTGAAGGTAGCGAACCCGATGCAGAGTTGATCAGTTACACGATTAATGAGCTGTGGCAAGATCCCG
ATCAGCAATGGTCCCACATTATTCAAGAAGCTATTGAAACCCAACAGACCGTCAACTTTGATTACCAATTGATGATTGAC
GAAGAACCGGTCTGGTTTACGGCTAATGTTTCTCCTCTCTTAGATAGCTCCGTGGTCTGGGTGGCCCGTAACGTCACTGA
ACAAAAAGACTCCGTGGTCTGGGTGGCTCGCAACATCACCGAGCGAAAGCATTTCGAACATGAACTGCAACAGCTGAATG
AAGAGCTGGAACGATCCAATAGAGAGTTAGAACAGTTTGCCTACGTTGCCTCCCACGATTTACAGGAGCCCCTTCGCATG
GTGATTAGTTTTACCCAGTTGTTGGGGCAAAACTATGCGGGGCAACTCGATGGGCAGGCCGACCAAATTATTGGCTTTGC
AGTGGACGGAGCGACCCGCATGCAGCAGCTGATCCAAGATCTACTCAGCTATTCCCGAGTAGGGACCCAGGCCAAAGTTC
TGGAAACCGTTGACTGTAATGAAATTGTAGAGAGCGCTATCTCCAACCTCCAACTCTCCATCCAAGAAAGTGGGGCAACC
TTAGAACGATCGCCGTTACCCACCCTACAAGCCAATCCTCGTCAACTCACTCAACTCTTTCAAAATTTGATCGGCAATGC
CCTTAAATATCGTGGAGAACAAGTCCCCCATATTGAAATCAACTACAAGCAACAGAGAAAAGACTATCTCTTTTGGGTGA
AAGACAATGGCATTGGCATCGATCCAAAACATGCAGATCGGGTATTTATGGTGTTTCAGCGCTTACATACTCGCCAAGAG
TATTCCGGTACCGGCATTGGTTTAGCCATTTGCAAGAAAATAATTGATCAGCAAGGGGGCAAAATCTGGGTGGAATCAGA
AGTCGATCAAGGCTCAACATTTTTCTTCACATTGCCTATGGAATCTGCCAGTTGA

Upstream 100 bases:

>100_bases
AGGAAGCCTTGGCCTTGTGATTCACGCTAGTATCGATGCGGATTGCCTTTGGCATCGCATTTAGACAAAGCTAGATGGCA
CATGGTATTGACGTATTCCA

Downstream 100 bases:

>100_bases
AGCGCAGTATTCTAGAAGGTAGACGAATATTGGCCTTGCGCTTGTGTGAAGATTAATGCCCTGTCTAACGGTTGTTACTG
TTGAGGCAGAAAATTCTTTT

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MKQVMIREPLVTQPDTSVADAVAILYQAEANYLVVVEDQIPVGVVCDRTLVTTLATQLDLSITPVQSVMAPLPTLPLEQA
DDLPAVTQVMQTEGSSFVAIVDEASHLQGLITSDTLIQQSSASTPSDNVVSLQKRIKELENQVSDRQLLEAKLRSSEGKI
RAVFEAMKDLVFVCDVDKGEISNIEVAPTNSSEGSEPDAELISYTINELWQDPDQQWSHIIQEAIETQQTVNFDYQLMID
EEPVWFTANVSPLLDSSVVWVARNVTEQKDSVVWVARNITERKHFEHELQQLNEELERSNRELEQFAYVASHDLQEPLRM
VISFTQLLGQNYAGQLDGQADQIIGFAVDGATRMQQLIQDLLSYSRVGTQAKVLETVDCNEIVESAISNLQLSIQESGAT
LERSPLPTLQANPRQLTQLFQNLIGNALKYRGEQVPHIEINYKQQRKDYLFWVKDNGIGIDPKHADRVFMVFQRLHTRQE
YSGTGIGLAICKKIIDQQGGKIWVESEVDQGSTFFFTLPMESAS

Sequences:

>Translated_524_residues
MKQVMIREPLVTQPDTSVADAVAILYQAEANYLVVVEDQIPVGVVCDRTLVTTLATQLDLSITPVQSVMAPLPTLPLEQA
DDLPAVTQVMQTEGSSFVAIVDEASHLQGLITSDTLIQQSSASTPSDNVVSLQKRIKELENQVSDRQLLEAKLRSSEGKI
RAVFEAMKDLVFVCDVDKGEISNIEVAPTNSSEGSEPDAELISYTINELWQDPDQQWSHIIQEAIETQQTVNFDYQLMID
EEPVWFTANVSPLLDSSVVWVARNVTEQKDSVVWVARNITERKHFEHELQQLNEELERSNRELEQFAYVASHDLQEPLRM
VISFTQLLGQNYAGQLDGQADQIIGFAVDGATRMQQLIQDLLSYSRVGTQAKVLETVDCNEIVESAISNLQLSIQESGAT
LERSPLPTLQANPRQLTQLFQNLIGNALKYRGEQVPHIEINYKQQRKDYLFWVKDNGIGIDPKHADRVFMVFQRLHTRQE
YSGTGIGLAICKKIIDQQGGKIWVESEVDQGSTFFFTLPMESAS
>Mature_524_residues
MKQVMIREPLVTQPDTSVADAVAILYQAEANYLVVVEDQIPVGVVCDRTLVTTLATQLDLSITPVQSVMAPLPTLPLEQA
DDLPAVTQVMQTEGSSFVAIVDEASHLQGLITSDTLIQQSSASTPSDNVVSLQKRIKELENQVSDRQLLEAKLRSSEGKI
RAVFEAMKDLVFVCDVDKGEISNIEVAPTNSSEGSEPDAELISYTINELWQDPDQQWSHIIQEAIETQQTVNFDYQLMID
EEPVWFTANVSPLLDSSVVWVARNVTEQKDSVVWVARNITERKHFEHELQQLNEELERSNRELEQFAYVASHDLQEPLRM
VISFTQLLGQNYAGQLDGQADQIIGFAVDGATRMQQLIQDLLSYSRVGTQAKVLETVDCNEIVESAISNLQLSIQESGAT
LERSPLPTLQANPRQLTQLFQNLIGNALKYRGEQVPHIEINYKQQRKDYLFWVKDNGIGIDPKHADRVFMVFQRLHTRQE
YSGTGIGLAICKKIIDQQGGKIWVESEVDQGSTFFFTLPMESAS

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=335, Percent_Identity=27.7611940298507, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI48994928, Length=407, Percent_Identity=24.5700245700246, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081816, Length=245, Percent_Identity=26.530612244898, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=27.5193798449612, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=30.1255230125523, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789149, Length=245, Percent_Identity=25.3061224489796, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=28.3185840707965, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=267, Percent_Identity=23.2209737827715, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=28.3261802575107, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=26.2931034482759, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=26.6129032258064, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58737; Mature: 58737

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVMIREPLVTQPDTSVADAVAILYQAEANYLVVVEDQIPVGVVCDRTLVTTLATQLDL
CCCCCCCCCCCCCCCCHHHHHHHHHEECCCCEEEEEECCCCCCEEECHHHHHHHHHHHCC
SITPVQSVMAPLPTLPLEQADDLPAVTQVMQTEGSSFVAIVDEASHLQGLITSDTLIQQS
EECCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCC
SASTPSDNVVSLQKRIKELENQVSDRQLLEAKLRSSEGKIRAVFEAMKDLVFVCDVDKGE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEEECCCCC
ISNIEVAPTNSSEGSEPDAELISYTINELWQDPDQQWSHIIQEAIETQQTVNFDYQLMID
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
EEPVWFTANVSPLLDSSVVWVARNVTEQKDSVVWVARNITERKHFEHELQQLNEELERSN
CCCEEEECCCCHHHCCCHHEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
RELEQFAYVASHDLQEPLRMVISFTQLLGQNYAGQLDGQADQIIGFAVDGATRMQQLIQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEECCHHHHHHHHHH
LLSYSRVGTQAKVLETVDCNEIVESAISNLQLSIQESGATLERSPLPTLQANPRQLTQLF
HHHHHHCCCHHHHHHHCCHHHHHHHHHHHCEEEEECCCCEECCCCCCCCCCCHHHHHHHH
QNLIGNALKYRGEQVPHIEINYKQQRKDYLFWVKDNGIGIDPKHADRVFMVFQRLHTRQE
HHHHHHHHHHCCCCCCEEEECCHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
YSGTGIGLAICKKIIDQQGGKIWVESEVDQGSTFFFTLPMESAS
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MKQVMIREPLVTQPDTSVADAVAILYQAEANYLVVVEDQIPVGVVCDRTLVTTLATQLDL
CCCCCCCCCCCCCCCCHHHHHHHHHEECCCCEEEEEECCCCCCEEECHHHHHHHHHHHCC
SITPVQSVMAPLPTLPLEQADDLPAVTQVMQTEGSSFVAIVDEASHLQGLITSDTLIQQS
EECCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCC
SASTPSDNVVSLQKRIKELENQVSDRQLLEAKLRSSEGKIRAVFEAMKDLVFVCDVDKGE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEEECCCCC
ISNIEVAPTNSSEGSEPDAELISYTINELWQDPDQQWSHIIQEAIETQQTVNFDYQLMID
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
EEPVWFTANVSPLLDSSVVWVARNVTEQKDSVVWVARNITERKHFEHELQQLNEELERSN
CCCEEEECCCCHHHCCCHHEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
RELEQFAYVASHDLQEPLRMVISFTQLLGQNYAGQLDGQADQIIGFAVDGATRMQQLIQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEECCHHHHHHHHHH
LLSYSRVGTQAKVLETVDCNEIVESAISNLQLSIQESGATLERSPLPTLQANPRQLTQLF
HHHHHHCCCHHHHHHHCCHHHHHHHHHHHCEEEEECCCCEECCCCCCCCCCCHHHHHHHH
QNLIGNALKYRGEQVPHIEINYKQQRKDYLFWVKDNGIGIDPKHADRVFMVFQRLHTRQE
HHHHHHHHHHCCCCCCEEEECCHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
YSGTGIGLAICKKIIDQQGGKIWVESEVDQGSTFFFTLPMESAS
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]