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The map label for this gene is aatB [H]

Identifier: 158333381

GI number: 158333381

Start: 152670

End: 153842

Strand: Direct

Name: aatB [H]

Synonym: AM1_0153

Alternate gene names: 158333381

Gene position: 152670-153842 (Clockwise)

Preceding gene: 158333380

Following gene: 158333382

Centisome position: 2.35

GC content: 50.3

Gene sequence:

>1173_bases
ATGCCTAAGCCATCGGCCCGCGTTGAAGCGGTTCAGGCTCCTATTATCCCCATTATTGGCGATCTGATTCGCCAGCATCC
TGGCACCCTGTCCCTCGGACAAGGGGTCGCTTCCTATGGTCCACCGCCAGAAGCCCTAGCCCAGGTAGCCACCTTTCACC
AAAATCCTGGGGTGCATCTCTATCAGTCCGTGCAGGGAATCCCGCCCCTTGTGGATGCGATCGCCCAGAAGCTACAGGCT
GAAAATCAGTTGCGCTTTCACCGTGACCAAATTATGGTGACGGCGGGGGGCAATATGGCGTTTATGAATGCGGTCCTCGC
CATTCTCGATCCAGGGGATGAGGTGATTCTGCAAACGCCTTACTACTTCAACCATGAGATGGCCATTCGGTTGGCCAACG
GTCAACCCGTCTGTGTTCCAACGGATCAGCAGTATCAACTCCAGCTCGATCAGATTGAAGCCGCCATTACCGAGCGAACA
CGGGCAATTGTGACGGTTTCTCCGAATAATCCATCGGGGGCAGTGTATTCAGCAGCGGATTTACAAGCAGTGAATCAGTT
GTGTTTGGAACGTAATCTTTATCACATTAGTGATGAAACCTACGAGTACTTTACCTATGACGGCATTGAGCATATTTCAC
CGGGTCGTTTTGACCCTGAGCAAACCCATACAATTTCCCTGTTTACCCTCTCCAAGGCTTATGGCTTCGCCAGTTGGCGG
ATCGGCTATATGGTGACTCCTCTGCATCTGCAAGAGGCACTTCAAAAAATTCAGGATACGTTGCTGATTTGCCCACCAGT
GGTATCTCAGTATGCAGCGGTTGGTGCGCTGCAAGTGGGACGGGGGTATTGTCATCAACATTTGGCTACTCTGACAGGAA
AGAGGAATCTGGTACAGAAGGCCCTTCTGCCTCTTGAGAAGGTATTTGTACCCACTAGTTCAGGTGCGTTTTATGTGTTG
ATTAAGGTCGATTGTGACTTACCTGATCGAGTTTTGGTAGAACAGTTGATTCGTGATTATCGAGTGGCGGTCATTCCGGG
GAGTGCGTTTGGTATGGAGGCGGGCTGCTATCTGCGGATTGCTTATGGCGCTTTGGATAAAGCTACACTAGCTGAAGGAT
TGAATCGATTGGTAAAGGGTTTAAAAACAATAGCAGGAGACCCAAAAAAGTAG

Upstream 100 bases:

>100_bases
ATTGGGACGCTTACGAAGCTTTGGTTCAAGCCATGACCGACCGCAAGTCGGTGGCGGAATGCTGCCAGATTCTGGGGCAA
CACTGCACGGTTGCCGTCTA

Downstream 100 bases:

>100_bases
TTTGGCACCAGGATTATCTCCCATTTAATCCATAAAAATAATATTCATAAAAAATAATTCGCTCGAAGGGCAAAAAGGAA
CGGGGGCAGAACACTAGAAG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPKPSARVEAVQAPIIPIIGDLIRQHPGTLSLGQGVASYGPPPEALAQVATFHQNPGVHLYQSVQGIPPLVDAIAQKLQA
ENQLRFHRDQIMVTAGGNMAFMNAVLAILDPGDEVILQTPYYFNHEMAIRLANGQPVCVPTDQQYQLQLDQIEAAITERT
RAIVTVSPNNPSGAVYSAADLQAVNQLCLERNLYHISDETYEYFTYDGIEHISPGRFDPEQTHTISLFTLSKAYGFASWR
IGYMVTPLHLQEALQKIQDTLLICPPVVSQYAAVGALQVGRGYCHQHLATLTGKRNLVQKALLPLEKVFVPTSSGAFYVL
IKVDCDLPDRVLVEQLIRDYRVAVIPGSAFGMEAGCYLRIAYGALDKATLAEGLNRLVKGLKTIAGDPKK

Sequences:

>Translated_390_residues
MPKPSARVEAVQAPIIPIIGDLIRQHPGTLSLGQGVASYGPPPEALAQVATFHQNPGVHLYQSVQGIPPLVDAIAQKLQA
ENQLRFHRDQIMVTAGGNMAFMNAVLAILDPGDEVILQTPYYFNHEMAIRLANGQPVCVPTDQQYQLQLDQIEAAITERT
RAIVTVSPNNPSGAVYSAADLQAVNQLCLERNLYHISDETYEYFTYDGIEHISPGRFDPEQTHTISLFTLSKAYGFASWR
IGYMVTPLHLQEALQKIQDTLLICPPVVSQYAAVGALQVGRGYCHQHLATLTGKRNLVQKALLPLEKVFVPTSSGAFYVL
IKVDCDLPDRVLVEQLIRDYRVAVIPGSAFGMEAGCYLRIAYGALDKATLAEGLNRLVKGLKTIAGDPKK
>Mature_389_residues
PKPSARVEAVQAPIIPIIGDLIRQHPGTLSLGQGVASYGPPPEALAQVATFHQNPGVHLYQSVQGIPPLVDAIAQKLQAE
NQLRFHRDQIMVTAGGNMAFMNAVLAILDPGDEVILQTPYYFNHEMAIRLANGQPVCVPTDQQYQLQLDQIEAAITERTR
AIVTVSPNNPSGAVYSAADLQAVNQLCLERNLYHISDETYEYFTYDGIEHISPGRFDPEQTHTISLFTLSKAYGFASWRI
GYMVTPLHLQEALQKIQDTLLICPPVVSQYAAVGALQVGRGYCHQHLATLTGKRNLVQKALLPLEKVFVPTSSGAFYVLI
KVDCDLPDRVLVEQLIRDYRVAVIPGSAFGMEAGCYLRIAYGALDKATLAEGLNRLVKGLKTIAGDPKK

Specific function: Involved in symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=355, Percent_Identity=27.0422535211268, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI56713256, Length=355, Percent_Identity=27.0422535211268, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=26.5151515151515, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=26.5151515151515, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=24.4224422442244, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788627, Length=336, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1786816, Length=360, Percent_Identity=26.9444444444444, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788722, Length=368, Percent_Identity=25.2717391304348, Blast_Score=102, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=387, Percent_Identity=26.8733850129199, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=387, Percent_Identity=26.8733850129199, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=428, Percent_Identity=25.4672897196262, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=356, Percent_Identity=21.9101123595506, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=232, Percent_Identity=28.448275862069, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6323118, Length=376, Percent_Identity=24.7340425531915, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28573069, Length=368, Percent_Identity=27.7173913043478, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646114, Length=368, Percent_Identity=27.7173913043478, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573067, Length=368, Percent_Identity=27.7173913043478, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28573065, Length=368, Percent_Identity=27.7173913043478, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI18859735, Length=311, Percent_Identity=23.7942122186495, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42726; Mature: 42595

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPSARVEAVQAPIIPIIGDLIRQHPGTLSLGQGVASYGPPPEALAQVATFHQNPGVHL
CCCCCCHHHHHHCCHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCHH
YQSVQGIPPLVDAIAQKLQAENQLRFHRDQIMVTAGGNMAFMNAVLAILDPGDEVILQTP
HHHHCCCCHHHHHHHHHHHHHHHHEEEECEEEEEECCCHHHHHHHHHEECCCCCEEEECC
YYFNHEMAIRLANGQPVCVPTDQQYQLQLDQIEAAITERTRAIVTVSPNNPSGAVYSAAD
CEECCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEHHH
LQAVNQLCLERNLYHISDETYEYFTYDGIEHISPGRFDPEQTHTISLFTLSKAYGFASWR
HHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCEEE
IGYMVTPLHLQEALQKIQDTLLICPPVVSQYAAVGALQVGRGYCHQHLATLTGKRNLVQK
ECEEECHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
ALLPLEKVFVPTSSGAFYVLIKVDCDLPDRVLVEQLIRDYRVAVIPGSAFGMEAGCYLRI
HHCCHHHHEEECCCCCEEEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEE
AYGALDKATLAEGLNRLVKGLKTIAGDPKK
EECCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PKPSARVEAVQAPIIPIIGDLIRQHPGTLSLGQGVASYGPPPEALAQVATFHQNPGVHL
CCCCCHHHHHHCCHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCHH
YQSVQGIPPLVDAIAQKLQAENQLRFHRDQIMVTAGGNMAFMNAVLAILDPGDEVILQTP
HHHHCCCCHHHHHHHHHHHHHHHHEEEECEEEEEECCCHHHHHHHHHEECCCCCEEEECC
YYFNHEMAIRLANGQPVCVPTDQQYQLQLDQIEAAITERTRAIVTVSPNNPSGAVYSAAD
CEECCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEHHH
LQAVNQLCLERNLYHISDETYEYFTYDGIEHISPGRFDPEQTHTISLFTLSKAYGFASWR
HHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCEEE
IGYMVTPLHLQEALQKIQDTLLICPPVVSQYAAVGALQVGRGYCHQHLATLTGKRNLVQK
ECEEECHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
ALLPLEKVFVPTSSGAFYVLIKVDCDLPDRVLVEQLIRDYRVAVIPGSAFGMEAGCYLRI
HHCCHHHHEEECCCCCEEEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEE
AYGALDKATLAEGLNRLVKGLKTIAGDPKK
EECCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]