Click here to switch to the map view.

The map label for this gene is ucpA [C]

Identifier: 158333274

GI number: 158333274

Start: 44798

End: 45481

Strand: Direct

Name: ucpA [C]

Synonym: AM1_0044

Alternate gene names: 158333274

Gene position: 44798-45481 (Clockwise)

Preceding gene: 158333273

Following gene: 158333275

Centisome position: 0.69

GC content: 49.85

Gene sequence:

>684_bases
ATGAGCCGTAAAATTGTCATTACCGGGGTCACCCAGGGACTGGGGGAAGCCCTCGCGATTGGGTTTATTCAAGCAGGGCA
TACCGTATGGGGTTGCGGTCGAACCACTGCCTCTATTAATCATCTGGCTCAGCAATATACATCCCCCCATCATTTTTCGA
CTGTTGATGTTGCCCAAGCCCAGCAGGTTCAAGCTTGGGCCAACCAGCTTTTGCAAACCGATGAACCCCCCGATATCGTC
ATCAATAATGCAGGGGTCATCAATACCGTCGCTCCTCTATGGGAAGTGCCCGAACCAGATATTAGTGATGTATTGGATGT
CAACGTCAAAGGCACCATCAACATCATTCGTAGTTTTCTCCCTAGCATGAAAACTAAAGGCCAAGGGATCATTATCAATT
TCAGTTCTGGATGGGGACGGTCAACGTCCCCTGGTGTAGCCCCCTACTGCGCATCCAAATGGGCGATTGAAGGTCTAAAT
CAGGCTTTTGCCCAAGAAGTTCCTCCCGGCATCGCCACAATTGCATTGAACCCGGGCATCATTCATACTGAAATGCTGGA
AACCTGTTTTGGTCAGCAAGCCCGCAGTTATCCCTCCCCCACCGCATGGGCACAAAAAGCCGTTCCATTTATTCTGGGCC
TTTCTGAAAACGATAACGGTCAAGCCTTAACTGTCCCGCAATAA

Upstream 100 bases:

>100_bases
AACCTTCCCGGTCCAAAAAGCATTTCAGCGCTGAAATACTTAGCCAAAGACGATAATCCTCAGGTTGCAGCCGCAGCCAC
TGTCGCCTTAGAGCTGATAC

Downstream 100 bases:

>100_bases
GGTTTTGGTATTAAATTCGGTTTGCAGGTATATAGAGGGAGATATTCGATGGAGGAGCTAGTCCACTTAACATCAGCAGG
TAACACCTATGGAGGCTGCT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSRKIVITGVTQGLGEALAIGFIQAGHTVWGCGRTTASINHLAQQYTSPHHFSTVDVAQAQQVQAWANQLLQTDEPPDIV
INNAGVINTVAPLWEVPEPDISDVLDVNVKGTINIIRSFLPSMKTKGQGIIINFSSGWGRSTSPGVAPYCASKWAIEGLN
QAFAQEVPPGIATIALNPGIIHTEMLETCFGQQARSYPSPTAWAQKAVPFILGLSENDNGQALTVPQ

Sequences:

>Translated_227_residues
MSRKIVITGVTQGLGEALAIGFIQAGHTVWGCGRTTASINHLAQQYTSPHHFSTVDVAQAQQVQAWANQLLQTDEPPDIV
INNAGVINTVAPLWEVPEPDISDVLDVNVKGTINIIRSFLPSMKTKGQGIIINFSSGWGRSTSPGVAPYCASKWAIEGLN
QAFAQEVPPGIATIALNPGIIHTEMLETCFGQQARSYPSPTAWAQKAVPFILGLSENDNGQALTVPQ
>Mature_226_residues
SRKIVITGVTQGLGEALAIGFIQAGHTVWGCGRTTASINHLAQQYTSPHHFSTVDVAQAQQVQAWANQLLQTDEPPDIVI
NNAGVINTVAPLWEVPEPDISDVLDVNVKGTINIIRSFLPSMKTKGQGIIINFSSGWGRSTSPGVAPYCASKWAIEGLNQ
AFAQEVPPGIATIALNPGIIHTEMLETCFGQQARSYPSPTAWAQKAVPFILGLSENDNGQALTVPQ

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=29.8429319371728, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=30.9278350515464, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI223718074, Length=202, Percent_Identity=30.6930693069307, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI150247226, Length=185, Percent_Identity=28.1081081081081, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI142976729, Length=194, Percent_Identity=25.7731958762887, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=27.8947368421053, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI15277342, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=211, Percent_Identity=30.3317535545024, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367175, Length=189, Percent_Identity=31.7460317460317, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787820, Length=169, Percent_Identity=27.2189349112426, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786812, Length=187, Percent_Identity=26.2032085561497, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790717, Length=212, Percent_Identity=27.3584905660377, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786701, Length=190, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789208, Length=198, Percent_Identity=27.2727272727273, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=181, Percent_Identity=23.2044198895028, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=28.125, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=28.125, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=29.5918367346939, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=201, Percent_Identity=27.363184079602, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=202, Percent_Identity=27.2277227722772, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=25.7894736842105, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=25.7894736842105, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=29.0155440414508, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322226, Length=238, Percent_Identity=23.109243697479, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=30.5882352941176, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21358495, Length=189, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639444, Length=186, Percent_Identity=29.5698924731183, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24584748, Length=224, Percent_Identity=26.3392857142857, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21357041, Length=189, Percent_Identity=26.984126984127, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI161076933, Length=224, Percent_Identity=26.3392857142857, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24643142, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640492, Length=168, Percent_Identity=26.7857142857143, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571387, Length=199, Percent_Identity=28.643216080402, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24581726, Length=167, Percent_Identity=26.3473053892216, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=27.6595744680851, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571526, Length=230, Percent_Identity=24.7826086956522, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24663911, Length=198, Percent_Identity=25.7575757575758, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644339, Length=200, Percent_Identity=27, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24238; Mature: 24107

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKIVITGVTQGLGEALAIGFIQAGHTVWGCGRTTASINHLAQQYTSPHHFSTVDVAQA
CCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHH
QQVQAWANQLLQTDEPPDIVINNAGVINTVAPLWEVPEPDISDVLDVNVKGTINIIRSFL
HHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHEECCCCHHHHHHHHHH
PSMKTKGQGIIINFSSGWGRSTSPGVAPYCASKWAIEGLNQAFAQEVPPGIATIALNPGI
HHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
IHTEMLETCFGQQARSYPSPTAWAQKAVPFILGLSENDNGQALTVPQ
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCCEEECCC
>Mature Secondary Structure 
SRKIVITGVTQGLGEALAIGFIQAGHTVWGCGRTTASINHLAQQYTSPHHFSTVDVAQA
CCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHH
QQVQAWANQLLQTDEPPDIVINNAGVINTVAPLWEVPEPDISDVLDVNVKGTINIIRSFL
HHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHEECCCCHHHHHHHHHH
PSMKTKGQGIIINFSSGWGRSTSPGVAPYCASKWAIEGLNQAFAQEVPPGIATIALNPGI
HHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
IHTEMLETCFGQQARSYPSPTAWAQKAVPFILGLSENDNGQALTVPQ
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]