Click here to switch to the map view.

The map label for this gene is zwf [H]

Identifier: 158318751

GI number: 158318751

Start: 8564402

End: 8565946

Strand: Reverse

Name: zwf [H]

Synonym: Franean1_7022

Alternate gene names: 158318751

Gene position: 8565946-8564402 (Counterclockwise)

Preceding gene: 158318752

Following gene: 158318750

Centisome position: 95.37

GC content: 59.42

Gene sequence:

>1545_bases
ATGCAGAACCTCACTCACGCACAGTGCGACAACCCGCACGGCAGGTTCATTTCGATAGGAGAACCCATGCCGCAGCTTAT
GTCGGTTGCCCCCTGCGAGATAGTAGTCTTCGGCGGCACAGGGGATCTGGCGATGCGCAAACTGATGCCAGCGCTGTACC
ACCGCGACCGAGACGGGCAACTCACCCCCGACTCGCGGGTCATTGCCGTGTCCCGGGCCGGACTCGATGATGCCGGATAC
CGCGACAAAGTTGATTCTGAACTGCGCCGGTTCGTCCCGGAGCTAATACACGAGCCGGATGTCCTAGCTCGCTTTATCCA
ACGCCTGCACCACATCACGGTCGACGTGGCGGAGCACAGCACCTGGGATGAACTGCGGACACTTCTGGCGGACGGAAAAG
ACCATGTGCGCGTCTTCTACCTTGCCTGTGCCCCACAACTGTTCGGGCCAACCTGTGTAGGCTTGCAAACCAACGGATTA
GTGACCGATAACTCCAGGGTGGTCCTCGAGAAGCCACTTGGGCATGATCTGGTCTCCGCGCGCCGGATTAACGATGAAGT
CGGTGCGGTTTTTGCTGAGGAACAGATATTCCGTATCGACCACTACCTCGGTAAAGAAACCGTCCAGAACCTCCTTGTGC
TACGCTTCGCCAACTCCCTTCTTGAGCCGCTGTGGAATTCTGGTGCGATCGACCATGTACAGATTACGGTCGCAGAAACA
ATTGGCATCGGAGGGCGCGGCGACTATTACGATGGCTCGGGTGCCATACGTGACATGGTACAGAATCACCTTCTGCAACT
GCTCTGTCTGGTGGCGATGGAACCACCCAGCCGACTTGACCGCGAGGCGGTCCGCGACGAGAAGCTAAAGATTCTCCAGG
CCCTATCCCCACTGACACTCGGTGACGTGGAACGGTGCGTCGTCCGAGGACAGTACACGGCCGGACTCGTAGAGGGAGCT
CCAGTTCCTTCTTACCAGGACGAAGTTGATGGGAGCACGAGTACCACCGAGACGTTTGTGGCGCTGAAGGTCGAGGTCCA
GAACTGGCGCTGGTCCGGGGTACCCTTCTACCTGCGTACCGGCAAGAGGCTAGATCGTCATGCATCGGAGATCGTGGTTC
AGTTCCGACCGGTACCACATTCAATCTTCCCGGGTATCAAGGATGCGATTTCTCCTAACGCTCTTGTGCTGCGGCTGCAA
CCTGACGAGGGCGTACGCCTCCACTTGATGGCCAAAGAACCGGGCCCGGGCGGCGTGCGACTGCGTCCAGTCCACCTCAA
CCTCAGCTTCGCCGAGACTTTCAAGTCACGCCTGCCCGATGCCTACGAGCGGCTACTCATGGACGTCGTTCGTGGCAACC
CGACGTTGTTCATGCGACGCGACGAGGTCGAGGCCGCATGGGCGTGGGTGGAGCCCATCCTGGCCGCTCTGGCGGCGTCA
ATTGACTCACCGAGGCGCTACGCAGCTGGCACTGGTGGACCTGCTGCAGCGATCGCATTGATCGAACGTGACGGCCGCAC
GTGGCATGAGGAGGTAGCAGAATGA

Upstream 100 bases:

>100_bases
GGTTTCCGGTGTCGCTGGTGTGTAATTGACTGCTGCCACATCGGCGCCTCACGGTTCCCATCCGGATAACTTCTCGGTCG
GCAACAAACGAGGTACTGAC

Downstream 100 bases:

>100_bases
GTGTGAACACGGTCCTGCACCCGGTTGTCGCTGAGGTGACTGAACGGGTCGCCGCTCGCAGTGCGGCAACTCGCGAAGCC
TATCTCTCCCGCGTCCAGGC

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQNLTHAQCDNPHGRFISIGEPMPQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQLTPDSRVIAVSRAGLDDAGY
RDKVDSELRRFVPELIHEPDVLARFIQRLHHITVDVAEHSTWDELRTLLADGKDHVRVFYLACAPQLFGPTCVGLQTNGL
VTDNSRVVLEKPLGHDLVSARRINDEVGAVFAEEQIFRIDHYLGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAET
IGIGGRGDYYDGSGAIRDMVQNHLLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTLGDVERCVVRGQYTAGLVEGA
PVPSYQDEVDGSTSTTETFVALKVEVQNWRWSGVPFYLRTGKRLDRHASEIVVQFRPVPHSIFPGIKDAISPNALVLRLQ
PDEGVRLHLMAKEPGPGGVRLRPVHLNLSFAETFKSRLPDAYERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAAS
IDSPRRYAAGTGGPAAAIALIERDGRTWHEEVAE

Sequences:

>Translated_514_residues
MQNLTHAQCDNPHGRFISIGEPMPQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQLTPDSRVIAVSRAGLDDAGY
RDKVDSELRRFVPELIHEPDVLARFIQRLHHITVDVAEHSTWDELRTLLADGKDHVRVFYLACAPQLFGPTCVGLQTNGL
VTDNSRVVLEKPLGHDLVSARRINDEVGAVFAEEQIFRIDHYLGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAET
IGIGGRGDYYDGSGAIRDMVQNHLLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTLGDVERCVVRGQYTAGLVEGA
PVPSYQDEVDGSTSTTETFVALKVEVQNWRWSGVPFYLRTGKRLDRHASEIVVQFRPVPHSIFPGIKDAISPNALVLRLQ
PDEGVRLHLMAKEPGPGGVRLRPVHLNLSFAETFKSRLPDAYERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAAS
IDSPRRYAAGTGGPAAAIALIERDGRTWHEEVAE
>Mature_514_residues
MQNLTHAQCDNPHGRFISIGEPMPQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQLTPDSRVIAVSRAGLDDAGY
RDKVDSELRRFVPELIHEPDVLARFIQRLHHITVDVAEHSTWDELRTLLADGKDHVRVFYLACAPQLFGPTCVGLQTNGL
VTDNSRVVLEKPLGHDLVSARRINDEVGAVFAEEQIFRIDHYLGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAET
IGIGGRGDYYDGSGAIRDMVQNHLLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTLGDVERCVVRGQYTAGLVEGA
PVPSYQDEVDGSTSTTETFVALKVEVQNWRWSGVPFYLRTGKRLDRHASEIVVQFRPVPHSIFPGIKDAISPNALVLRLQ
PDEGVRLHLMAKEPGPGGVRLRPVHLNLSFAETFKSRLPDAYERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAAS
IDSPRRYAAGTGGPAAAIALIERDGRTWHEEVAE

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=480, Percent_Identity=37.0833333333333, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI109389365, Length=480, Percent_Identity=37.0833333333333, Blast_Score=299, Evalue=3e-81,
Organism=Homo sapiens, GI52145310, Length=506, Percent_Identity=30.8300395256917, Blast_Score=172, Evalue=8e-43,
Organism=Escherichia coli, GI1788158, Length=493, Percent_Identity=48.2758620689655, Blast_Score=467, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17538218, Length=488, Percent_Identity=37.7049180327869, Blast_Score=318, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6324088, Length=485, Percent_Identity=36.0824742268041, Blast_Score=298, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24643350, Length=478, Percent_Identity=35.9832635983264, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24643352, Length=478, Percent_Identity=35.9832635983264, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI221513548, Length=497, Percent_Identity=29.9798792756539, Blast_Score=201, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 57083; Mature: 57083

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLTHAQCDNPHGRFISIGEPMPQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQ
CCCCCCCCCCCCCCCEEECCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC
LTPDSRVIAVSRAGLDDAGYRDKVDSELRRFVPELIHEPDVLARFIQRLHHITVDVAEHS
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEHHCCC
TWDELRTLLADGKDHVRVFYLACAPQLFGPTCVGLQTNGLVTDNSRVVLEKPLGHDLVSA
CHHHHHHHHHCCCCCEEEEEEEECHHHCCCEEECEECCCEEECCCEEEEECCCCCHHHHH
RRINDEVGAVFAEEQIFRIDHYLGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAET
HHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHE
IGIGGRGDYYDGSGAIRDMVQNHLLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTL
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GDVERCVVRGQYTAGLVEGAPVPSYQDEVDGSTSTTETFVALKVEVQNWRWSGVPFYLRT
CCHHHHHHCCCCHHCCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEEECEEECCCCEEEEC
GKRLDRHASEIVVQFRPVPHSIFPGIKDAISPNALVLRLQPDEGVRLHLMAKEPGPGGVR
CCHHHHHHHHEEEEEECCCHHHCCCCHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCEE
LRPVHLNLSFAETFKSRLPDAYERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAAS
EEEEEEECHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
IDSPRRYAAGTGGPAAAIALIERDGRTWHEEVAE
CCCCHHHCCCCCCHHHEEEEEECCCCHHHHHHCC
>Mature Secondary Structure
MQNLTHAQCDNPHGRFISIGEPMPQLMSVAPCEIVVFGGTGDLAMRKLMPALYHRDRDGQ
CCCCCCCCCCCCCCCEEECCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC
LTPDSRVIAVSRAGLDDAGYRDKVDSELRRFVPELIHEPDVLARFIQRLHHITVDVAEHS
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEHHCCC
TWDELRTLLADGKDHVRVFYLACAPQLFGPTCVGLQTNGLVTDNSRVVLEKPLGHDLVSA
CHHHHHHHHHCCCCCEEEEEEEECHHHCCCEEECEECCCEEECCCEEEEECCCCCHHHHH
RRINDEVGAVFAEEQIFRIDHYLGKETVQNLLVLRFANSLLEPLWNSGAIDHVQITVAET
HHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHE
IGIGGRGDYYDGSGAIRDMVQNHLLQLLCLVAMEPPSRLDREAVRDEKLKILQALSPLTL
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GDVERCVVRGQYTAGLVEGAPVPSYQDEVDGSTSTTETFVALKVEVQNWRWSGVPFYLRT
CCHHHHHHCCCCHHCCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEEECEEECCCCEEEEC
GKRLDRHASEIVVQFRPVPHSIFPGIKDAISPNALVLRLQPDEGVRLHLMAKEPGPGGVR
CCHHHHHHHHEEEEEECCCHHHCCCCHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCEE
LRPVHLNLSFAETFKSRLPDAYERLLMDVVRGNPTLFMRRDEVEAAWAWVEPILAALAAS
EEEEEEECHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
IDSPRRYAAGTGGPAAAIALIERDGRTWHEEVAE
CCCCHHHCCCCCCHHHEEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA