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The map label for this gene is desA3 [H]

Identifier: 158318705

GI number: 158318705

Start: 8498733

End: 8499815

Strand: Reverse

Name: desA3 [H]

Synonym: Franean1_6974

Alternate gene names: 158318705

Gene position: 8499815-8498733 (Counterclockwise)

Preceding gene: 158318706

Following gene: 158318703

Centisome position: 94.63

GC content: 67.31

Gene sequence:

>1083_bases
ATGGCCAGGCGGACGGCACTCACCGCGGCCGAGGCCGACGAGTTCGGCCGCGCGCTCGACCAGCTCCGGGAGGAGGTTCT
CGCCGGCCGAGGGGAAGGCGATGCCCGGTACATCCGCAGGGTGATCGCCGTTCAGCGGGGCCTGGAGATGGGTGGGCGGG
TGGTGCTGTTCGCGTCTCTGCTGCCACCGGCATGGCTGGCGGGCACGACGATGCTCGCGACCGCCAAGATCCTGGAGAAC
ATGGAGATCGGGCACAACGTCCTGCACGGCCAGTGGGACTGGATGTGCGATCCCGAGATCCACTCGACCACCTGGGAATG
GGACTCGGCGTCACCCGCCGCGCAGTGGAAACACTCGCACAACTACGTGCACCACACCTACACGAACATCCTCGGCAAGG
ACCGGGACATCGGATACAGCCTGCTGCGCGTCAAGTCGGAGCAGCGCTGGCACCCCGCGTACCTCGCCCAGCCGCTCTAT
AATCTCGCACTCGCGGCGGTCTTCGAATGGGGGATCGCCCTGTACGACACCGAGATCGAGCGGGCCTGGCGGGGGGAGAA
AAGCTGGGGCCAGACGTGGGCGCAGCTCCAGGTGTCGCTGCGCAAGGCCGGGCGGCAGGCGGTCAAGGATTACGTGGCAT
TCCCGCTGCTGGCCGGCCCGGCGTTCCTGCCCGTCCTGTTCGCCAACCTCACCGCGAACGTCACCCGCAATGTCTGGGCA
CACACGATCATCTTCTGCGGTCACTTCCCGGAGGGAACGGAGGCCTTCACCGAGGAACAGGTCGAGGGGGAGACCCGCGG
CGGGTGGTATGTGCGGCAGGTGCTGGGCTCAGCCAACATCGACGGCCCGGCACTCCTGCACCTGATGAGTGGGAACCTGA
GTTTCCAGATCGAGCACCACCTGTTCCCCGATCTACCCAGCAACCGGTACGCACAGCTAGCCCCGCAGGTACGCGCCCTC
TGCGAACGCTTCGGCCTCCCCTACACCACCGGAGGACTGCTGCGACAGACGGCCAACGTGTGGAAGCGCGTCATCCGGCT
CTCGCTCCCCGGACCCGCCCCGGCGGTGGCCGACTCTCCATGA

Upstream 100 bases:

>100_bases
TGCGCACCGGGCGGGAGCACGGTGCGCAGGGCGAACTCGTCCAGACCTGCGTGTCGGGCGCGGCCGGCGACGTCGAGATC
GACCTTTGAAGGGGTGGGCA

Downstream 100 bases:

>100_bases
TCCGCTCATGGGGCCGGCGAACAAGCGGGTTTCGTGCGCGGGTAGAGGTCGCGCAGCAGGCAGACCTCGGCCAGATGGTG
GATCAGCTCGCGGTGGATGT

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(9)-desaturase; Stearoyl-CoA desaturase [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MARRTALTAAEADEFGRALDQLREEVLAGRGEGDARYIRRVIAVQRGLEMGGRVVLFASLLPPAWLAGTTMLATAKILEN
MEIGHNVLHGQWDWMCDPEIHSTTWEWDSASPAAQWKHSHNYVHHTYTNILGKDRDIGYSLLRVKSEQRWHPAYLAQPLY
NLALAAVFEWGIALYDTEIERAWRGEKSWGQTWAQLQVSLRKAGRQAVKDYVAFPLLAGPAFLPVLFANLTANVTRNVWA
HTIIFCGHFPEGTEAFTEEQVEGETRGGWYVRQVLGSANIDGPALLHLMSGNLSFQIEHHLFPDLPSNRYAQLAPQVRAL
CERFGLPYTTGGLLRQTANVWKRVIRLSLPGPAPAVADSP

Sequences:

>Translated_360_residues
MARRTALTAAEADEFGRALDQLREEVLAGRGEGDARYIRRVIAVQRGLEMGGRVVLFASLLPPAWLAGTTMLATAKILEN
MEIGHNVLHGQWDWMCDPEIHSTTWEWDSASPAAQWKHSHNYVHHTYTNILGKDRDIGYSLLRVKSEQRWHPAYLAQPLY
NLALAAVFEWGIALYDTEIERAWRGEKSWGQTWAQLQVSLRKAGRQAVKDYVAFPLLAGPAFLPVLFANLTANVTRNVWA
HTIIFCGHFPEGTEAFTEEQVEGETRGGWYVRQVLGSANIDGPALLHLMSGNLSFQIEHHLFPDLPSNRYAQLAPQVRAL
CERFGLPYTTGGLLRQTANVWKRVIRLSLPGPAPAVADSP
>Mature_359_residues
ARRTALTAAEADEFGRALDQLREEVLAGRGEGDARYIRRVIAVQRGLEMGGRVVLFASLLPPAWLAGTTMLATAKILENM
EIGHNVLHGQWDWMCDPEIHSTTWEWDSASPAAQWKHSHNYVHHTYTNILGKDRDIGYSLLRVKSEQRWHPAYLAQPLYN
LALAAVFEWGIALYDTEIERAWRGEKSWGQTWAQLQVSLRKAGRQAVKDYVAFPLLAGPAFLPVLFANLTANVTRNVWAH
TIIFCGHFPEGTEAFTEEQVEGETRGGWYVRQVLGSANIDGPALLHLMSGNLSFQIEHHLFPDLPSNRYAQLAPQVRALC
ERFGLPYTTGGLLRQTANVWKRVIRLSLPGPAPAVADSP

Specific function: Desaturates stearoyl-CoA to form oleoyl-CoA [H]

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Probable). Note=Has been shown to be membrane-associated but no reliable trans-membrane regions are predicted by bioinformatics tools [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Homo sapiens, GI13375616, Length=236, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: NA

Molecular weight: Translated: 40326; Mature: 40195

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRTALTAAEADEFGRALDQLREEVLAGRGEGDARYIRRVIAVQRGLEMGGRVVLFASL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHH
LPPAWLAGTTMLATAKILENMEIGHNVLHGQWDWMCDPEIHSTTWEWDSASPAAQWKHSH
CCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCC
NYVHHTYTNILGKDRDIGYSLLRVKSEQRWHPAYLAQPLYNLALAAVFEWGIALYDTEIE
CCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAWRGEKSWGQTWAQLQVSLRKAGRQAVKDYVAFPLLAGPAFLPVLFANLTANVTRNVWA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTIIFCGHFPEGTEAFTEEQVEGETRGGWYVRQVLGSANIDGPALLHLMSGNLSFQIEHH
HEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHEECCCEEEEEECC
LFPDLPSNRYAQLAPQVRALCERFGLPYTTGGLLRQTANVWKRVIRLSLPGPAPAVADSP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ARRTALTAAEADEFGRALDQLREEVLAGRGEGDARYIRRVIAVQRGLEMGGRVVLFASL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHH
LPPAWLAGTTMLATAKILENMEIGHNVLHGQWDWMCDPEIHSTTWEWDSASPAAQWKHSH
CCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCC
NYVHHTYTNILGKDRDIGYSLLRVKSEQRWHPAYLAQPLYNLALAAVFEWGIALYDTEIE
CCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAWRGEKSWGQTWAQLQVSLRKAGRQAVKDYVAFPLLAGPAFLPVLFANLTANVTRNVWA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTIIFCGHFPEGTEAFTEEQVEGETRGGWYVRQVLGSANIDGPALLHLMSGNLSFQIEHH
HEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHEECCCEEEEEECC
LFPDLPSNRYAQLAPQVRALCERFGLPYTTGGLLRQTANVWKRVIRLSLPGPAPAVADSP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]