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The map label for this gene is glcB [H]

Identifier: 158318701

GI number: 158318701

Start: 8494921

End: 8497098

Strand: Direct

Name: glcB [H]

Synonym: Franean1_6970

Alternate gene names: 158318701

Gene position: 8494921-8497098 (Clockwise)

Preceding gene: 158318698

Following gene: 158318702

Centisome position: 94.58

GC content: 72.36

Gene sequence:

>2178_bases
GTGCCTGACTACATCGACGTCGTCGGACTGCGCGTCGCCAGCGAGCTGCACCAGTTCGTCGCCGAGGAGGCGCTGCCCGG
GTCGGGTGTCGACCAGGCCGCGTTCTGGGCCGGCGCCACGGAGATCATCAACGATCTGACCCCGCGCAACCGGGAGCTAC
TGGCGCGGCGCGACGAGCTCCAGCAGGCTGTGGACGACTACCACCGGCGCACGCCGGGCCGGCCGGCGCAGAGCGACTAC
GCCGAGTTCCTGACCTCCATCGGCTACCTGCTCGACGAGCCCGCGCCGTTCACCATCACCACCGACGGCGTGGACGACGA
GATCGCGACCCAGGCCGGCCCGCAGCTGGTGGTGCCGCTGCTCAACGCGCGGTACGCGGTCAACGCCGCCAACGCCCGGT
GGGGCTCGCTCTACGACGCCCTGTACGGCAGCGACGTCATCGACGAGACAGACGGCAGGGAGCGCGCCGGCGGCTACAAC
CCGACCCGCGGCGCCGCGGTCATCGCCCGGGTCCGGGAGATCCTCGACCGGAGCTTCCCGCTGACCAGCGGCTCGCACGC
GGACGCGACCCGGTACGCGGTCGACGCCGACGGGCTCGTCGTCACCGTCGACGGGGCCGCCGTCCGGCTGGCCGACCCCG
CGCTGTTCGTCGGCTTCCGCGGCGAGGGCGACGAGCCGACGGCTGTCCTGCTGACCCATCACGGGCTGCACGTCGAGATC
CAGGTCGACCGGAACCACCCGGTCGGGGCGGGCGACCGCGCGGGCGTCAGCGACGTCGTCGTCGAGGCCGCCGTCACCAC
GATCATGGACCTGGAGGACTCGGTCGCGGCCGTCGACGCCGCGGACAAGGTGCTCGGCTACCGCAACTGGCTGCAGCTCA
TGCAGCGCCGGCTCACCGCCGAGGTGGACAAGGGCGGCCGCACCTTCACCCGGGTCCTCGCCGCCGACCGCGAGTACACG
ACCGCCGACGGCGGCACAGTCACCCTGCCCGGCCGGTCGATGTTGCTCATCCGCCAGGTCGGGCTGCTGATGACCACCGA
TGCGGTCCTCGACCGCGACGGCCGGCCGGTGCCCGAGGGCATCCTCGACGCGCTGGTCACCGGCCTGGGCAGCGTGCATG
ACCTGCGCGGCGACACCGCCGGCGGCAACTCCCGCACCGGCTCGGCGTACGTGGTCAAGCCCAAGATGCACGGCCCGGAC
GAGGTCGCCTTCACCGTCGAGCTGATGTCCCGCGTCGAGCGCCTCCTCCAGCTCCCGCCGGCGACGATCAAGCTCGGCAT
CATGGACGAGGAACGCCGCACCTCGGTCAACCTCAGGCGCTGCGTGTACGAGGCCCGGGACCGCGTCGTCTTCATCAACA
CCGGGTTCCTGGACCGGACCGGCGACGAGATCCACACCTCGATGCTCGCCGGGCCGATGGTCCGCAAGGCCGCCATGCGC
GAGGCGACGTGGATCCGCGTCTACGAGGACAACAACGTCGACGCCGGCCTCGCCCTCGGTTTCCCCGGGCGGGCGCAGAT
CGGCAAGGGCATGTGGGCCGCGCCGGACAATCTGGCCGACATGATGACGCAGAAGATCGGGCACCCGCTGGCCGGCGCGT
CCTGCGCCTGGGTGCCCTCGCCTACCGCCGCGGCGCTGCACGCACTGCACTACCACGAGGTCTCCGTGGCGGACCGGCAG
CGCGAGCTGGCCGGCCGCCGCCCGGCCGACCGGCTGGAGCTGCTCACCGTCCCGCTCGCGGAACCGGCGGCCGCCTGGTC
GCCGGAGGAGGTCGCCGCCGAGGTTGACAACAACGTCCAGGGCGTGCTCGGCTACGTCGTGCGCTGGGTCGAGCTCGGCA
TCGGCTGCTCCAAGGTGCCCGACCTGACCGGCACACCCCTGATGGAGGACCGCGCCACCTGCCGCATCTCCTCCCAGCAC
GTGGCCAACTGGCTGCGGCACGGCATCGTCTCCCGCGAGCAGGTCGAGGAGTCGCTGCGCCGGATGGCCGCGCTCGTCGA
CGCGCAGAACGCCGGCGAGCCGGGGTACCGGCCGATGGCCCCGGCCTTCGAGGAGCTGGCCTTCGCCGCCGCGCGGGCGC
TGCTACTCGAGGGCGCCGACCAGCCGAACGGCTACACCGAACCGCTGTTGCACGAGCACCGGCGCGCTCAGAAGAACAAG
GAGATGGTCCGCTCATGA

Upstream 100 bases:

>100_bases
CCCTGCGGTGACGCGGCCTGTGTTGACACCGTCCAACATCCCTCGGTAGCGTCCGATAAGCGAAAAGGCTATTCCACCAT
ACGAAATTCGGGATGGGCTA

Downstream 100 bases:

>100_bases
CGGCACTTCCGCTGGATGTGGCCCGGCAGATCGTCGCCGCGGCCCGGGCCGCGGGGCGCGAGCACGGTCTCAAGCCGCTC
ACGGTGGTCGTGCTGGACGC

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 724

Protein sequence:

>725_residues
MPDYIDVVGLRVASELHQFVAEEALPGSGVDQAAFWAGATEIINDLTPRNRELLARRDELQQAVDDYHRRTPGRPAQSDY
AEFLTSIGYLLDEPAPFTITTDGVDDEIATQAGPQLVVPLLNARYAVNAANARWGSLYDALYGSDVIDETDGRERAGGYN
PTRGAAVIARVREILDRSFPLTSGSHADATRYAVDADGLVVTVDGAAVRLADPALFVGFRGEGDEPTAVLLTHHGLHVEI
QVDRNHPVGAGDRAGVSDVVVEAAVTTIMDLEDSVAAVDAADKVLGYRNWLQLMQRRLTAEVDKGGRTFTRVLAADREYT
TADGGTVTLPGRSMLLIRQVGLLMTTDAVLDRDGRPVPEGILDALVTGLGSVHDLRGDTAGGNSRTGSAYVVKPKMHGPD
EVAFTVELMSRVERLLQLPPATIKLGIMDEERRTSVNLRRCVYEARDRVVFINTGFLDRTGDEIHTSMLAGPMVRKAAMR
EATWIRVYEDNNVDAGLALGFPGRAQIGKGMWAAPDNLADMMTQKIGHPLAGASCAWVPSPTAAALHALHYHEVSVADRQ
RELAGRRPADRLELLTVPLAEPAAAWSPEEVAAEVDNNVQGVLGYVVRWVELGIGCSKVPDLTGTPLMEDRATCRISSQH
VANWLRHGIVSREQVEESLRRMAALVDAQNAGEPGYRPMAPAFEELAFAAARALLLEGADQPNGYTEPLLHEHRRAQKNK
EMVRS

Sequences:

>Translated_725_residues
MPDYIDVVGLRVASELHQFVAEEALPGSGVDQAAFWAGATEIINDLTPRNRELLARRDELQQAVDDYHRRTPGRPAQSDY
AEFLTSIGYLLDEPAPFTITTDGVDDEIATQAGPQLVVPLLNARYAVNAANARWGSLYDALYGSDVIDETDGRERAGGYN
PTRGAAVIARVREILDRSFPLTSGSHADATRYAVDADGLVVTVDGAAVRLADPALFVGFRGEGDEPTAVLLTHHGLHVEI
QVDRNHPVGAGDRAGVSDVVVEAAVTTIMDLEDSVAAVDAADKVLGYRNWLQLMQRRLTAEVDKGGRTFTRVLAADREYT
TADGGTVTLPGRSMLLIRQVGLLMTTDAVLDRDGRPVPEGILDALVTGLGSVHDLRGDTAGGNSRTGSAYVVKPKMHGPD
EVAFTVELMSRVERLLQLPPATIKLGIMDEERRTSVNLRRCVYEARDRVVFINTGFLDRTGDEIHTSMLAGPMVRKAAMR
EATWIRVYEDNNVDAGLALGFPGRAQIGKGMWAAPDNLADMMTQKIGHPLAGASCAWVPSPTAAALHALHYHEVSVADRQ
RELAGRRPADRLELLTVPLAEPAAAWSPEEVAAEVDNNVQGVLGYVVRWVELGIGCSKVPDLTGTPLMEDRATCRISSQH
VANWLRHGIVSREQVEESLRRMAALVDAQNAGEPGYRPMAPAFEELAFAAARALLLEGADQPNGYTEPLLHEHRRAQKNK
EMVRS
>Mature_724_residues
PDYIDVVGLRVASELHQFVAEEALPGSGVDQAAFWAGATEIINDLTPRNRELLARRDELQQAVDDYHRRTPGRPAQSDYA
EFLTSIGYLLDEPAPFTITTDGVDDEIATQAGPQLVVPLLNARYAVNAANARWGSLYDALYGSDVIDETDGRERAGGYNP
TRGAAVIARVREILDRSFPLTSGSHADATRYAVDADGLVVTVDGAAVRLADPALFVGFRGEGDEPTAVLLTHHGLHVEIQ
VDRNHPVGAGDRAGVSDVVVEAAVTTIMDLEDSVAAVDAADKVLGYRNWLQLMQRRLTAEVDKGGRTFTRVLAADREYTT
ADGGTVTLPGRSMLLIRQVGLLMTTDAVLDRDGRPVPEGILDALVTGLGSVHDLRGDTAGGNSRTGSAYVVKPKMHGPDE
VAFTVELMSRVERLLQLPPATIKLGIMDEERRTSVNLRRCVYEARDRVVFINTGFLDRTGDEIHTSMLAGPMVRKAAMRE
ATWIRVYEDNNVDAGLALGFPGRAQIGKGMWAAPDNLADMMTQKIGHPLAGASCAWVPSPTAAALHALHYHEVSVADRQR
ELAGRRPADRLELLTVPLAEPAAAWSPEEVAAEVDNNVQGVLGYVVRWVELGIGCSKVPDLTGTPLMEDRATCRISSQHV
ANWLRHGIVSREQVEESLRRMAALVDAQNAGEPGYRPMAPAFEELAFAAARALLLEGADQPNGYTEPLLHEHRRAQKNKE
MVRS

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=727, Percent_Identity=55.2957359009629, Blast_Score=801, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 78687; Mature: 78555

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDYIDVVGLRVASELHQFVAEEALPGSGVDQAAFWAGATEIINDLTPRNRELLARRDEL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHCCCCCCHHHHHHHHHH
QQAVDDYHRRTPGRPAQSDYAEFLTSIGYLLDEPAPFTITTDGVDDEIATQAGPQLVVPL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCEEEHHH
LNARYAVNAANARWGSLYDALYGSDVIDETDGRERAGGYNPTRGAAVIARVREILDRSFP
HCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCC
LTSGSHADATRYAVDADGLVVTVDGAAVRLADPALFVGFRGEGDEPTAVLLTHHGLHVEI
CCCCCCCCCCEEEECCCCEEEEECCCEEEEECCEEEEEECCCCCCCCEEEEEECCEEEEE
QVDRNHPVGAGDRAGVSDVVVEAAVTTIMDLEDSVAAVDAADKVLGYRNWLQLMQRRLTA
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVDKGGRTFTRVLAADREYTTADGGTVTLPGRSMLLIRQVGLLMTTDAVLDRDGRPVPEG
HHCCCCHHHHHHHHCCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
ILDALVTGLGSVHDLRGDTAGGNSRTGSAYVVKPKMHGPDEVAFTVELMSRVERLLQLPP
HHHHHHHHCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
ATIKLGIMDEERRTSVNLRRCVYEARDRVVFINTGFLDRTGDEIHTSMLAGPMVRKAAMR
CEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
EATWIRVYEDNNVDAGLALGFPGRAQIGKGMWAAPDNLADMMTQKIGHPLAGASCAWVPS
CCEEEEEEECCCCCCCEEECCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
PTAAALHALHYHEVSVADRQRELAGRRPADRLELLTVPLAEPAAAWSPEEVAAEVDNNVQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCHH
GVLGYVVRWVELGIGCSKVPDLTGTPLMEDRATCRISSQHVANWLRHGIVSREQVEESLR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCHHHHHHHHH
RMAALVDAQNAGEPGYRPMAPAFEELAFAAARALLLEGADQPNGYTEPLLHEHRRAQKNK
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
EMVRS
HHHCC
>Mature Secondary Structure 
PDYIDVVGLRVASELHQFVAEEALPGSGVDQAAFWAGATEIINDLTPRNRELLARRDEL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHCCCCCCHHHHHHHHHH
QQAVDDYHRRTPGRPAQSDYAEFLTSIGYLLDEPAPFTITTDGVDDEIATQAGPQLVVPL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCEEEHHH
LNARYAVNAANARWGSLYDALYGSDVIDETDGRERAGGYNPTRGAAVIARVREILDRSFP
HCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCC
LTSGSHADATRYAVDADGLVVTVDGAAVRLADPALFVGFRGEGDEPTAVLLTHHGLHVEI
CCCCCCCCCCEEEECCCCEEEEECCCEEEEECCEEEEEECCCCCCCCEEEEEECCEEEEE
QVDRNHPVGAGDRAGVSDVVVEAAVTTIMDLEDSVAAVDAADKVLGYRNWLQLMQRRLTA
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVDKGGRTFTRVLAADREYTTADGGTVTLPGRSMLLIRQVGLLMTTDAVLDRDGRPVPEG
HHCCCCHHHHHHHHCCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
ILDALVTGLGSVHDLRGDTAGGNSRTGSAYVVKPKMHGPDEVAFTVELMSRVERLLQLPP
HHHHHHHHCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
ATIKLGIMDEERRTSVNLRRCVYEARDRVVFINTGFLDRTGDEIHTSMLAGPMVRKAAMR
CEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
EATWIRVYEDNNVDAGLALGFPGRAQIGKGMWAAPDNLADMMTQKIGHPLAGASCAWVPS
CCEEEEEEECCCCCCCEEECCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
PTAAALHALHYHEVSVADRQRELAGRRPADRLELLTVPLAEPAAAWSPEEVAAEVDNNVQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCHH
GVLGYVVRWVELGIGCSKVPDLTGTPLMEDRATCRISSQHVANWLRHGIVSREQVEESLR
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHCCCCHHHHHHHHH
RMAALVDAQNAGEPGYRPMAPAFEELAFAAARALLLEGADQPNGYTEPLLHEHRRAQKNK
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
EMVRS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA