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The map label for this gene is mmpL3 [H]

Identifier: 158318529

GI number: 158318529

Start: 8286045

End: 8288246

Strand: Reverse

Name: mmpL3 [H]

Synonym: Franean1_6797

Alternate gene names: 158318529

Gene position: 8288246-8286045 (Counterclockwise)

Preceding gene: 158318531

Following gene: 158318528

Centisome position: 92.28

GC content: 69.16

Gene sequence:

>2202_bases
ATGTTCGAGCGTCTGGGACGGACGATGTTCAGTCGGCGGCGGTGGGTCATCAGCCTGGCCGTGGTCTTCGCCGCGTTCGG
CGGCATCTGGGGTACGCGGGTATTCGGCGCGCTGACCACCGGTGGGTTCGACGACCCGGCCAGCGAGAGTGCCCATGCGC
TCGACCGTGCCGAGGCGACACTTGGCCGAACGGGCAATGACCTGGTCGTTCTCTACAGCAGCCCGAGCGCGACGGTCGAC
GACCCGGCGTTCCGGCGGGCCGTGACCGAGACACTGGACGCGCTCCCGGACGACGTGGTGACCAGGACGATCACCTACTG
GGGCACGAACAGCCCGGCGCTGGTCAGCGACGACCGGCGCTCCGCCTACGCCGTGCTGACCGTGACCGGCGACGAGGTGC
AACGCGTCGACGGGCTGAAGGAGATCGAGGACGGGCTGGCCGCTCCCGGCCTTCAGACCCAGGTCGGCGGCTACACCGCG
GTCAGTCGCGACATCGGCGAGCGGGTGGCGGCAGACATCGGCCGTGCCGAGACGATCTCCATACCGGTGCTGCTTGTCCT
GCTGGTGGTCGTCTTCGGTGGCGTGGCCGCGGCGAGCCTGCCGCTCGTGATCGGTGGTCTGGCCATCCTCGGGGCCTTCA
CCGCGCTACGTGGGCTGAGCTACCTGACCGACGTCTCGGTCTTCTCGATCAACGTGGTGACGATCCTCGGGCTTGGTCTG
GCGATCGACTACGGCCTGTTCATGACCGGACGGTTCCGGGAGGAGATCGCCCGTGGGCTGGGCGTCGAGGACGCGATCGT
TCGGACGACGGCCACCGCCGGCCACACCGTCGCGGTCTCCGGCGTCACCGTCGCGGTCTCGTTGTCCGGGCTGCTGATCT
TCCCGATGCCCTTTCTCCGCTCGATGGGATTCGGCGGGCTGTCCGCGGTCGTAGTCGCGATGGTGGCGGCGCTGACCGTG
CTGCCCGCCCTGCTCGGTGTCCTGGGCCACCGGGTGGACGCGCTCTCCGTGCGGCGGTTCCGTCGCATTCCGCGCCCGGC
TCCCACAGCGGGCGAGGTCGAGCACGGGTTCTGGTACCGCCTCGCGCACAGCATCATGCGGCGCCCGGTCATCTACGCGG
TCGGGGTGCTCGCGGTCCTGCTGCTGGCCGGTTCGCCGTTTCTCCGGGTGGAGTTCGGCGGTGTCGACCCCAGGGTGCTC
CCGGCGGGTACCGAGAGCCGCGTCGTCTCCGAGACCGTCGACCGGGACTTCGTCCGCAACAGCCAGTTGCCGATCGAGGC
GATCGTGACCTCATCCGGCCGCGCCGGTCTGGAACGACAGGCCGGGCTGGAGCGATACGTCACCGCGGTCCGGGACGTCG
ACGGCGTGACCGGAGCCGAGGTCACCGGCCAGTCCGGGAGCGTCACCCGGGTCGCCGTCAGTTACCAGGACGACCCGATC
TCGGCGCAGGCGCGGGACCTGGTGCGCCGGATTCGGAACGTCCCCGCACCGCCTGGCGGCGAGGTGCTGGTGGGTGGCTT
CACCGCGGAGCTGACCGACCAGCTCGACACCACCGCCGACCTGCTGCCCTGGATGGCGCTGATCATCGTCGGCGCGACGT
TCGTCCTGCTGTTCCTCGCCTTCGGCTCGGTCGTGCTGCCGATCAAGGCGATCGTGATGAACATCCTGTCGCTCGGCGCC
TCGTTCGGCGCACTGGTCCTGATCTTCCAGGACGGCCACCTGTCCGGTCCGCTGAACTTCACACCCACCGGGACGCTGGA
GGCGACCCAGCCGATCCTCGTGCTCGCGATCGTGTTCGGGCTGTCGACGGACTACGAGGTCTTCCTGATGTCCCGGATCC
GCGAGGTGTACGACCGGACCGGCGACAACACCACGGCGGTCGCAGTCGGACTGCAGCGCAGCGGCCGGATCATCACCAGT
GCCGCGCTACTCATCCTGGTCGTGATCGGGCTGTTCTCGACCTCCGGCATCACCTTCATCAAGCTGATCGGGGTAGCGAT
GATCATTGCCGTCCTGGTGGACGCGACGATCGTCCGGGCGCTGCTCGTACCGGCCACGATGCGCCTGCTCGGGAACACGA
ACTGGTGGGCGCCGGCGCCACTGCGGCGCTTCTACGCCCACCACGGCCTGCGCGAAGGTGTGGACCCGCCTCCATCGGCG
CCTGATCTCCGTCCCGCACCAGCCCACACGCAATCCGACTGA

Upstream 100 bases:

>100_bases
GCTCCGGTCAAAGGCCTGTGACTCTCGTCCCGCGTGCGGCAGGTTGCCGTCTGTGTCCGTACCGCGACTAGAGGTCGCAC
AGAATGCCCGGGGAGCAGAG

Downstream 100 bases:

>100_bases
TGGATGGTCAGCCGTGCCAGCGCCGGGACGCGGGTCGGTACGCAGGGCTGGTGTCTTTGGGCACCGGGTCCGCGGCCACC
TCGAGTAACAGATCTCGGCG

Product: MMPL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 733; Mature: 733

Protein sequence:

>733_residues
MFERLGRTMFSRRRWVISLAVVFAAFGGIWGTRVFGALTTGGFDDPASESAHALDRAEATLGRTGNDLVVLYSSPSATVD
DPAFRRAVTETLDALPDDVVTRTITYWGTNSPALVSDDRRSAYAVLTVTGDEVQRVDGLKEIEDGLAAPGLQTQVGGYTA
VSRDIGERVAADIGRAETISIPVLLVLLVVVFGGVAAASLPLVIGGLAILGAFTALRGLSYLTDVSVFSINVVTILGLGL
AIDYGLFMTGRFREEIARGLGVEDAIVRTTATAGHTVAVSGVTVAVSLSGLLIFPMPFLRSMGFGGLSAVVVAMVAALTV
LPALLGVLGHRVDALSVRRFRRIPRPAPTAGEVEHGFWYRLAHSIMRRPVIYAVGVLAVLLLAGSPFLRVEFGGVDPRVL
PAGTESRVVSETVDRDFVRNSQLPIEAIVTSSGRAGLERQAGLERYVTAVRDVDGVTGAEVTGQSGSVTRVAVSYQDDPI
SAQARDLVRRIRNVPAPPGGEVLVGGFTAELTDQLDTTADLLPWMALIIVGATFVLLFLAFGSVVLPIKAIVMNILSLGA
SFGALVLIFQDGHLSGPLNFTPTGTLEATQPILVLAIVFGLSTDYEVFLMSRIREVYDRTGDNTTAVAVGLQRSGRIITS
AALLILVVIGLFSTSGITFIKLIGVAMIIAVLVDATIVRALLVPATMRLLGNTNWWAPAPLRRFYAHHGLREGVDPPPSA
PDLRPAPAHTQSD

Sequences:

>Translated_733_residues
MFERLGRTMFSRRRWVISLAVVFAAFGGIWGTRVFGALTTGGFDDPASESAHALDRAEATLGRTGNDLVVLYSSPSATVD
DPAFRRAVTETLDALPDDVVTRTITYWGTNSPALVSDDRRSAYAVLTVTGDEVQRVDGLKEIEDGLAAPGLQTQVGGYTA
VSRDIGERVAADIGRAETISIPVLLVLLVVVFGGVAAASLPLVIGGLAILGAFTALRGLSYLTDVSVFSINVVTILGLGL
AIDYGLFMTGRFREEIARGLGVEDAIVRTTATAGHTVAVSGVTVAVSLSGLLIFPMPFLRSMGFGGLSAVVVAMVAALTV
LPALLGVLGHRVDALSVRRFRRIPRPAPTAGEVEHGFWYRLAHSIMRRPVIYAVGVLAVLLLAGSPFLRVEFGGVDPRVL
PAGTESRVVSETVDRDFVRNSQLPIEAIVTSSGRAGLERQAGLERYVTAVRDVDGVTGAEVTGQSGSVTRVAVSYQDDPI
SAQARDLVRRIRNVPAPPGGEVLVGGFTAELTDQLDTTADLLPWMALIIVGATFVLLFLAFGSVVLPIKAIVMNILSLGA
SFGALVLIFQDGHLSGPLNFTPTGTLEATQPILVLAIVFGLSTDYEVFLMSRIREVYDRTGDNTTAVAVGLQRSGRIITS
AALLILVVIGLFSTSGITFIKLIGVAMIIAVLVDATIVRALLVPATMRLLGNTNWWAPAPLRRFYAHHGLREGVDPPPSA
PDLRPAPAHTQSD
>Mature_733_residues
MFERLGRTMFSRRRWVISLAVVFAAFGGIWGTRVFGALTTGGFDDPASESAHALDRAEATLGRTGNDLVVLYSSPSATVD
DPAFRRAVTETLDALPDDVVTRTITYWGTNSPALVSDDRRSAYAVLTVTGDEVQRVDGLKEIEDGLAAPGLQTQVGGYTA
VSRDIGERVAADIGRAETISIPVLLVLLVVVFGGVAAASLPLVIGGLAILGAFTALRGLSYLTDVSVFSINVVTILGLGL
AIDYGLFMTGRFREEIARGLGVEDAIVRTTATAGHTVAVSGVTVAVSLSGLLIFPMPFLRSMGFGGLSAVVVAMVAALTV
LPALLGVLGHRVDALSVRRFRRIPRPAPTAGEVEHGFWYRLAHSIMRRPVIYAVGVLAVLLLAGSPFLRVEFGGVDPRVL
PAGTESRVVSETVDRDFVRNSQLPIEAIVTSSGRAGLERQAGLERYVTAVRDVDGVTGAEVTGQSGSVTRVAVSYQDDPI
SAQARDLVRRIRNVPAPPGGEVLVGGFTAELTDQLDTTADLLPWMALIIVGATFVLLFLAFGSVVLPIKAIVMNILSLGA
SFGALVLIFQDGHLSGPLNFTPTGTLEATQPILVLAIVFGLSTDYEVFLMSRIREVYDRTGDNTTAVAVGLQRSGRIITS
AALLILVVIGLFSTSGITFIKLIGVAMIIAVLVDATIVRALLVPATMRLLGNTNWWAPAPLRRFYAHHGLREGVDPPPSA
PDLRPAPAHTQSD

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 77618; Mature: 77618

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERLGRTMFSRRRWVISLAVVFAAFGGIWGTRVFGALTTGGFDDPASESAHALDRAEAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LGRTGNDLVVLYSSPSATVDDPAFRRAVTETLDALPDDVVTRTITYWGTNSPALVSDDRR
HCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCEEECCCC
SAYAVLTVTGDEVQRVDGLKEIEDGLAAPGLQTQVGGYTAVSRDIGERVAADIGRAETIS
CEEEEEEECCHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEH
IPVLLVLLVVVFGGVAAASLPLVIGGLAILGAFTALRGLSYLTDVSVFSINVVTILGLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIDYGLFMTGRFREEIARGLGVEDAIVRTTATAGHTVAVSGVTVAVSLSGLLIFPMPFLR
HHHHHHHCCCHHHHHHHHCCCCCHHHHHEECCCCCEEEECCEEEEEEECCHHEECHHHHH
SMGFGGLSAVVVAMVAALTVLPALLGVLGHRVDALSVRRFRRIPRPAPTAGEVEHGFWYR
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
LAHSIMRRPVIYAVGVLAVLLLAGSPFLRVEFGGVDPRVLPAGTESRVVSETVDRDFVRN
HHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHC
SQLPIEAIVTSSGRAGLERQAGLERYVTAVRDVDGVTGAEVTGQSGSVTRVAVSYQDDPI
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEECCCCC
SAQARDLVRRIRNVPAPPGGEVLVGGFTAELTDQLDTTADLLPWMALIIVGATFVLLFLA
CHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSVVLPIKAIVMNILSLGASFGALVLIFQDGHLSGPLNFTPTGTLEATQPILVLAIVFG
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LSTDYEVFLMSRIREVYDRTGDNTTAVAVGLQRSGRIITSAALLILVVIGLFSTSGITFI
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
KLIGVAMIIAVLVDATIVRALLVPATMRLLGNTNWWAPAPLRRFYAHHGLREGVDPPPSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHCCCCCCCCC
PDLRPAPAHTQSD
CCCCCCCCCCCCC
>Mature Secondary Structure
MFERLGRTMFSRRRWVISLAVVFAAFGGIWGTRVFGALTTGGFDDPASESAHALDRAEAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LGRTGNDLVVLYSSPSATVDDPAFRRAVTETLDALPDDVVTRTITYWGTNSPALVSDDRR
HCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCEEECCCC
SAYAVLTVTGDEVQRVDGLKEIEDGLAAPGLQTQVGGYTAVSRDIGERVAADIGRAETIS
CEEEEEEECCHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEH
IPVLLVLLVVVFGGVAAASLPLVIGGLAILGAFTALRGLSYLTDVSVFSINVVTILGLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIDYGLFMTGRFREEIARGLGVEDAIVRTTATAGHTVAVSGVTVAVSLSGLLIFPMPFLR
HHHHHHHCCCHHHHHHHHCCCCCHHHHHEECCCCCEEEECCEEEEEEECCHHEECHHHHH
SMGFGGLSAVVVAMVAALTVLPALLGVLGHRVDALSVRRFRRIPRPAPTAGEVEHGFWYR
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
LAHSIMRRPVIYAVGVLAVLLLAGSPFLRVEFGGVDPRVLPAGTESRVVSETVDRDFVRN
HHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHC
SQLPIEAIVTSSGRAGLERQAGLERYVTAVRDVDGVTGAEVTGQSGSVTRVAVSYQDDPI
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEECCCCC
SAQARDLVRRIRNVPAPPGGEVLVGGFTAELTDQLDTTADLLPWMALIIVGATFVLLFLA
CHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSVVLPIKAIVMNILSLGASFGALVLIFQDGHLSGPLNFTPTGTLEATQPILVLAIVFG
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LSTDYEVFLMSRIREVYDRTGDNTTAVAVGLQRSGRIITSAALLILVVIGLFSTSGITFI
CCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
KLIGVAMIIAVLVDATIVRALLVPATMRLLGNTNWWAPAPLRRFYAHHGLREGVDPPPSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHCCCCCCCCC
PDLRPAPAHTQSD
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]