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The map label for this gene is degS [H]

Identifier: 158318431

GI number: 158318431

Start: 8136138

End: 8138003

Strand: Direct

Name: degS [H]

Synonym: Franean1_6699

Alternate gene names: 158318431

Gene position: 8136138-8138003 (Clockwise)

Preceding gene: 158318430

Following gene: 158318432

Centisome position: 90.58

GC content: 74.38

Gene sequence:

>1866_bases
GTGCGCGAGCATGCGGGCGGGCGGCTCCTCCCGGGGACGGCGGCCGTGGGAGAGGCACCCGGCGGCGCCGCGATCGACGG
CGCCGCCGCGCCCGCGGTGGACCACCGGCGCAAGCCCGCGGCGTCCATGACCGGAAACGGGGACGACCTCCGCCGGAGGT
ACGGGGTGCCGGCACTCGCCGTGGTGGGCGCGGTCATCGGGGCGGTGGTGCTCTGGCTTTCCGACGGCGGTCGGGACGAG
GACACGACAAGCACCCTCTTCTCCGGCCTCGTCGGCGGGCTCTACCTGCTGACCGGTTCCGTCACGCACCTGCGCCGACC
GGGTCGGCTGGGGTTGCGGATGGTGATGGTCGGCATCTCCTGGTTCGCCGAGGACCTGCAGGTCTCGAGCTACCCGGTGC
CGCACACCGTCGGAATGTTCTTCCGGTGCGTCGCCTCGGGATGTCTCGTGCACCTCCTGCTGGCCTTCCCCGAGGGGCGG
CTACGGACGCGCACCGAGCGGGTGGTGACCGGCGGCGTGTACGTGTTCGTGCTCGGCCTCGTGCCGCTGGGCGTCCCGTT
CTACCGGTCGTTGACGCCGAACCTGCTGCTCGTCGCCAACCTGTCCCGGATGCAGGACCTGCTGGTCGACAGCACGCAGG
TGGTGTTCGCCGTGATTGTCGGCGGGCTGCTCGTCCGGCGCTGGGTTGTCGCCACCCCGCCGGCCCGCCGGGTGCTCGCG
CCGGTGTACGGCGTCGGGCTCGTCGGGAGCGTCGCGTCGCTGCTCCACCCGGCGCTGACCGGTTCGACCGCGCTACTGAT
CAACGAGGTCGCCCACCTCGCGACCCTCGGGCTCCCGGTGGCGTTCCTGGCCGGCGCGCTGCGCGTCCGGCTCGGCCGCA
CGGCCGTCGGGGACCTCCTGCTGCAGCTGCCGCAGATGCCGCCTACCGAGCTGCGCCACCTGCTGGCCCGCGCGCTCGGC
GACCCCACGCTGCGCATCGCCTACCCCCATCCGGACCATGCCGGTTCGGACGCCGTTTCCACCGACGGATACCTGGACGC
CGACGGGCAGCCCGTGACGCCCCGTCCGGATGACGCGGTGACCCCGGTCCGGCGCGGCCTGCGCGTGGTCGCCGTGCTCC
TGCACGACCCGGCGCTGCGCGCCGACCGGCATGTCCTGCACGCCGTGACGGCGGCCGCGGCGCTGGAGCTGGACAATCAG
CGGCTCGCCGCTGAGGTGCGGGCCCAGCTCACCGAGGTCCGGGCGTCCCGGGTCCGCATCGTCGCGGCGGCCGACGAGCA
GCGCCGCCGGATCGAACGCGATCTGCACGACGGTGCCCAGCAGCAGCTCGTCACGGCCGCGCTGATCCTGCGGCTGGCGC
GGGACCGGCTCGGCCCTGCTCCCCCCGACCCCGAGCTCGGCACGCTCCTGCGGCGGGCCGCCGACGGGCTGGAGGCGGCG
GTGAAGGAGCTGCGCGAGCTCGCCCGCGGCATCCACCCCGCGGTGCTAACGGAGGCCGGGCTGTTGCCCGCGTTGCGGAC
GCTCGCCGCCCGTTCGGCATTCCCCGTGCAGATCGTCGACGGGCCCGCGTTGCCGCCGCTGCCGGACCCGGTGGCCGCGA
CGGCCTACTTCGTCGCCGCCGAGGCAGTGACGAACGCGGCGAAGCACGCCCGTGCCAACCAGATCCACGTCCACGTGCGG
ACGTCCGGTAACCGGCTGCTCGTCACCGTTGCCGATGACGGCGTCGGCGGCGCCGACATGAGCGCCGGAACCGGCCTGCT
CGGGCTGCGCGACCGGACGGCCGCGCTCGACGGCAGCCTGGTCGTGCGCAGTCTCCCCGGCGCCGGGACGTCTGTCCACG
CCGAGTTACCTCTGGAGGGGTCTTGA

Upstream 100 bases:

>100_bases
ACTGCCTTGTCGATGGTCACTGGCTGGCGAATAATCGATCAGTAACCTGAGCGATCCGCCGGTCAGGTTCCGGGCAGTTC
GGGGGGTGGAGAAGGCGGCC

Downstream 100 bases:

>100_bases
CCACCACCGCACCCGCCCCGGCCGAGGACGTGCCGCGCGTCGTCCTCGCCGACGACGCCTCGCTGTTCCGGGCGGCGCTC
GCCGAGCTGCTGGAACGCGA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MREHAGGRLLPGTAAVGEAPGGAAIDGAAAPAVDHRRKPAASMTGNGDDLRRRYGVPALAVVGAVIGAVVLWLSDGGRDE
DTTSTLFSGLVGGLYLLTGSVTHLRRPGRLGLRMVMVGISWFAEDLQVSSYPVPHTVGMFFRCVASGCLVHLLLAFPEGR
LRTRTERVVTGGVYVFVLGLVPLGVPFYRSLTPNLLLVANLSRMQDLLVDSTQVVFAVIVGGLLVRRWVVATPPARRVLA
PVYGVGLVGSVASLLHPALTGSTALLINEVAHLATLGLPVAFLAGALRVRLGRTAVGDLLLQLPQMPPTELRHLLARALG
DPTLRIAYPHPDHAGSDAVSTDGYLDADGQPVTPRPDDAVTPVRRGLRVVAVLLHDPALRADRHVLHAVTAAAALELDNQ
RLAAEVRAQLTEVRASRVRIVAAADEQRRRIERDLHDGAQQQLVTAALILRLARDRLGPAPPDPELGTLLRRAADGLEAA
VKELRELARGIHPAVLTEAGLLPALRTLAARSAFPVQIVDGPALPPLPDPVAATAYFVAAEAVTNAAKHARANQIHVHVR
TSGNRLLVTVADDGVGGADMSAGTGLLGLRDRTAALDGSLVVRSLPGAGTSVHAELPLEGS

Sequences:

>Translated_621_residues
MREHAGGRLLPGTAAVGEAPGGAAIDGAAAPAVDHRRKPAASMTGNGDDLRRRYGVPALAVVGAVIGAVVLWLSDGGRDE
DTTSTLFSGLVGGLYLLTGSVTHLRRPGRLGLRMVMVGISWFAEDLQVSSYPVPHTVGMFFRCVASGCLVHLLLAFPEGR
LRTRTERVVTGGVYVFVLGLVPLGVPFYRSLTPNLLLVANLSRMQDLLVDSTQVVFAVIVGGLLVRRWVVATPPARRVLA
PVYGVGLVGSVASLLHPALTGSTALLINEVAHLATLGLPVAFLAGALRVRLGRTAVGDLLLQLPQMPPTELRHLLARALG
DPTLRIAYPHPDHAGSDAVSTDGYLDADGQPVTPRPDDAVTPVRRGLRVVAVLLHDPALRADRHVLHAVTAAAALELDNQ
RLAAEVRAQLTEVRASRVRIVAAADEQRRRIERDLHDGAQQQLVTAALILRLARDRLGPAPPDPELGTLLRRAADGLEAA
VKELRELARGIHPAVLTEAGLLPALRTLAARSAFPVQIVDGPALPPLPDPVAATAYFVAAEAVTNAAKHARANQIHVHVR
TSGNRLLVTVADDGVGGADMSAGTGLLGLRDRTAALDGSLVVRSLPGAGTSVHAELPLEGS
>Mature_621_residues
MREHAGGRLLPGTAAVGEAPGGAAIDGAAAPAVDHRRKPAASMTGNGDDLRRRYGVPALAVVGAVIGAVVLWLSDGGRDE
DTTSTLFSGLVGGLYLLTGSVTHLRRPGRLGLRMVMVGISWFAEDLQVSSYPVPHTVGMFFRCVASGCLVHLLLAFPEGR
LRTRTERVVTGGVYVFVLGLVPLGVPFYRSLTPNLLLVANLSRMQDLLVDSTQVVFAVIVGGLLVRRWVVATPPARRVLA
PVYGVGLVGSVASLLHPALTGSTALLINEVAHLATLGLPVAFLAGALRVRLGRTAVGDLLLQLPQMPPTELRHLLARALG
DPTLRIAYPHPDHAGSDAVSTDGYLDADGQPVTPRPDDAVTPVRRGLRVVAVLLHDPALRADRHVLHAVTAAAALELDNQ
RLAAEVRAQLTEVRASRVRIVAAADEQRRRIERDLHDGAQQQLVTAALILRLARDRLGPAPPDPELGTLLRRAADGLEAA
VKELRELARGIHPAVLTEAGLLPALRTLAARSAFPVQIVDGPALPPLPDPVAATAYFVAAEAVTNAAKHARANQIHVHVR
TSGNRLLVTVADDGVGGADMSAGTGLLGLRDRTAALDGSLVVRSLPGAGTSVHAELPLEGS

Specific function: Member of the two-component regulatory system degS/degU. Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=315, Percent_Identity=30.1587301587302, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65194; Mature: 65194

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREHAGGRLLPGTAAVGEAPGGAAIDGAAAPAVDHRRKPAASMTGNGDDLRRRYGVPALA
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHCCCHHH
VVGAVIGAVVLWLSDGGRDEDTTSTLFSGLVGGLYLLTGSVTHLRRPGRLGLRMVMVGIS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHH
WFAEDLQVSSYPVPHTVGMFFRCVASGCLVHLLLAFPEGRLRTRTERVVTGGVYVFVLGL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHH
VPLGVPFYRSLTPNLLLVANLSRMQDLLVDSTQVVFAVIVGGLLVRRWVVATPPARRVLA
HHHCCHHHHHCCCCEEEEECHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PVYGVGLVGSVASLLHPALTGSTALLINEVAHLATLGLPVAFLAGALRVRLGRTAVGDLL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LQLPQMPPTELRHLLARALGDPTLRIAYPHPDHAGSDAVSTDGYLDADGQPVTPRPDDAV
HHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCH
TPVRRGLRVVAVLLHDPALRADRHVLHAVTAAAALELDNQRLAAEVRAQLTEVRASRVRI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEE
VAAADEQRRRIERDLHDGAQQQLVTAALILRLARDRLGPAPPDPELGTLLRRAADGLEAA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VKELRELARGIHPAVLTEAGLLPALRTLAARSAFPVQIVDGPALPPLPDPVAATAYFVAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHH
EAVTNAAKHARANQIHVHVRTSGNRLLVTVADDGVGGADMSAGTGLLGLRDRTAALDGSL
HHHHHHHHHCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCEECCCHHHHCCCCC
VVRSLPGAGTSVHAELPLEGS
CEEECCCCCCEEEEECCCCCC
>Mature Secondary Structure
MREHAGGRLLPGTAAVGEAPGGAAIDGAAAPAVDHRRKPAASMTGNGDDLRRRYGVPALA
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHCCCHHH
VVGAVIGAVVLWLSDGGRDEDTTSTLFSGLVGGLYLLTGSVTHLRRPGRLGLRMVMVGIS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHH
WFAEDLQVSSYPVPHTVGMFFRCVASGCLVHLLLAFPEGRLRTRTERVVTGGVYVFVLGL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHH
VPLGVPFYRSLTPNLLLVANLSRMQDLLVDSTQVVFAVIVGGLLVRRWVVATPPARRVLA
HHHCCHHHHHCCCCEEEEECHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PVYGVGLVGSVASLLHPALTGSTALLINEVAHLATLGLPVAFLAGALRVRLGRTAVGDLL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LQLPQMPPTELRHLLARALGDPTLRIAYPHPDHAGSDAVSTDGYLDADGQPVTPRPDDAV
HHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCH
TPVRRGLRVVAVLLHDPALRADRHVLHAVTAAAALELDNQRLAAEVRAQLTEVRASRVRI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEE
VAAADEQRRRIERDLHDGAQQQLVTAALILRLARDRLGPAPPDPELGTLLRRAADGLEAA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VKELRELARGIHPAVLTEAGLLPALRTLAARSAFPVQIVDGPALPPLPDPVAATAYFVAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHH
EAVTNAAKHARANQIHVHVRTSGNRLLVTVADDGVGGADMSAGTGLLGLRDRTAALDGSL
HHHHHHHHHCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCEECCCHHHHCCCCC
VVRSLPGAGTSVHAELPLEGS
CEEECCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3141378; 3141377; 9384377; 3136143 [H]