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The map label for this gene is 158317930

Identifier: 158317930

GI number: 158317930

Start: 7517426

End: 7519045

Strand: Reverse

Name: 158317930

Synonym: Franean1_6188

Alternate gene names: NA

Gene position: 7519045-7517426 (Counterclockwise)

Preceding gene: 158317935

Following gene: 158317929

Centisome position: 83.71

GC content: 74.32

Gene sequence:

>1620_bases
ATGCTCCGGAATCTTCCATTGGACAGGGTCGTCGGCGGGCCCGTCCCGGCGCGGCGGCGGCCGGCGGGCTGCCACGCTGG
TGGCATGGATGCGGTGACGCTGTCGGTGGTGTCCAGTGCGCTGGGCGGCATCGCCGAGGAGATGGGGACGCTGCTCGTCC
GGAGCGCGTACTCGTCCAACATCAAGGAGCGGCGCGACTGCTCGGCGGCGATCTTCGACGCGGACGCCCGGATGATCGCT
CAGGCCGCCCACGTGCCGGTGCACCTGGGCGCCATGTACGAGTCGGTCCGGGTGGTCGCCGAGCGCGGGCCGCTGCCTGG
TGACGTGTGGGTGCTCAACGACCCGTTCTCCGGCGGGAACCACCTGCCCGACGTCACGCTGATCTCCCCGCTCGCGTTTG
ACGGCGAGGTGGTCGGCTACGCGGCCACCCGTGCGCACCACTCCGACATGGGCGGGATGCGTCCCGGGTCGATGCCCGCG
GACTCCACCGAGATCTTCGCCGAGGGCCTGATCATCCCGCCGGTCCGGCTCGTCCGGGCGGGGCGCTGGGAGGAGGACCT
GCTCGACCTCATCTGCGCGAACTCGCGGACGCCCGACCTGCGCCGCGGTGACCTGCGCGCGCAGGCGGCGGCGAACGGGC
TGGCCGCCACCCGGCTGGCCGAGCTCGCGCGCCGGCACGGCACCGGGCTCGTCCTGGAGTCGTTCGCCGAGGTACTCCGC
TACGGCGAGCGGCGCAGCCGGGCAGTGATCGCGCGGCTGCCCGACGGCGTCCACCGGGTGGAGAGCGAGCTCGAGGGCGA
CGGCGTCGACGACCGGGACATAGCGCTGCGGGTCGCGGTGACCATCGAGGGCGACGGCATCACCGTCGACTTCACCGGCA
CGTCACCGGCGGTGCGCGGCAACGTCAACTGCCCGCGCGCCGTGACCCGCTCCGCGTGCTGCTTCGCGCTGCGGGTGCTG
CTGCCCGACGACGTCCCGACCGGCGACGGCACCTACGCCCCGCTGACCGTGGTGACCGAGCCCGGTTCGCTGGTCGACGC
GCAACGCCCGTCCGCCGTCGTGGCGGGCAACGTGGAGACATCGCAGCGCATCGCCGACACGGTGCTGGCGGCCCTGCGGC
TGGCGGTCGGCGCCGGGCCGGACGTCCTGGCGGCGCCCGGGCAGGGGACGATGAACAATCTGGTGATCGGCGGCGCGACC
TGGACGTACTACGAGACGCTGGGCGGGGGGCAGGGCGCGTCCGCCCGCGGCCGTGGCCCCTCCGGGGTGCACGTGGGGAT
GACGAACACGCTGAACACCCCGATCGAGGCGCTCGAGCTGGAGTACCCGATGCGGGTGGAGCGCTACGAGCTGGCCGACG
GCACGGGTGGGCCCGGCAGGCATCCGGGCGGGGACGGCCTCGTGCGCTCGGTGCGGGTGCTGGAGCCGGCGACGCTGTCC
GTCCTGACCGACCGGCGGCGGCACGCGCCCGGTGGGGTGGCGGGAGGTGGGCCCGGCGCGGTCGGGCACAACGATGTTGA
CGGTGTTCCGCTCCCACCGAAGGCGAGCCGGCAGCTCCCTGCCGGGTCGGTCGTCACCCTGCGCACACCGGGCGGTGGCG
GATGGGGCCCCCCGCCGTAA

Upstream 100 bases:

>100_bases
GTTGGTCTAGATAAACGCAATATAAACTCCAATGGATGGGCAATTCTCCCGTTATCGTTCGGTATGTCATTTTTGTTCCG
ATATCTACTGATTAAGGCAA

Downstream 100 bases:

>100_bases
TTCTTCGGGATCGACATCATCACGCAGGGTGTACATCTGGCTGTCAATCGTTATCTGGACGGCCACGCGCCCACCTTCGC
GCGCGTGTTCGACTGCGGCA

Product: 5-oxoprolinase

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MLRNLPLDRVVGGPVPARRRPAGCHAGGMDAVTLSVVSSALGGIAEEMGTLLVRSAYSSNIKERRDCSAAIFDADARMIA
QAAHVPVHLGAMYESVRVVAERGPLPGDVWVLNDPFSGGNHLPDVTLISPLAFDGEVVGYAATRAHHSDMGGMRPGSMPA
DSTEIFAEGLIIPPVRLVRAGRWEEDLLDLICANSRTPDLRRGDLRAQAAANGLAATRLAELARRHGTGLVLESFAEVLR
YGERRSRAVIARLPDGVHRVESELEGDGVDDRDIALRVAVTIEGDGITVDFTGTSPAVRGNVNCPRAVTRSACCFALRVL
LPDDVPTGDGTYAPLTVVTEPGSLVDAQRPSAVVAGNVETSQRIADTVLAALRLAVGAGPDVLAAPGQGTMNNLVIGGAT
WTYYETLGGGQGASARGRGPSGVHVGMTNTLNTPIEALELEYPMRVERYELADGTGGPGRHPGGDGLVRSVRVLEPATLS
VLTDRRRHAPGGVAGGGPGAVGHNDVDGVPLPPKASRQLPAGSVVTLRTPGGGGWGPPP

Sequences:

>Translated_539_residues
MLRNLPLDRVVGGPVPARRRPAGCHAGGMDAVTLSVVSSALGGIAEEMGTLLVRSAYSSNIKERRDCSAAIFDADARMIA
QAAHVPVHLGAMYESVRVVAERGPLPGDVWVLNDPFSGGNHLPDVTLISPLAFDGEVVGYAATRAHHSDMGGMRPGSMPA
DSTEIFAEGLIIPPVRLVRAGRWEEDLLDLICANSRTPDLRRGDLRAQAAANGLAATRLAELARRHGTGLVLESFAEVLR
YGERRSRAVIARLPDGVHRVESELEGDGVDDRDIALRVAVTIEGDGITVDFTGTSPAVRGNVNCPRAVTRSACCFALRVL
LPDDVPTGDGTYAPLTVVTEPGSLVDAQRPSAVVAGNVETSQRIADTVLAALRLAVGAGPDVLAAPGQGTMNNLVIGGAT
WTYYETLGGGQGASARGRGPSGVHVGMTNTLNTPIEALELEYPMRVERYELADGTGGPGRHPGGDGLVRSVRVLEPATLS
VLTDRRRHAPGGVAGGGPGAVGHNDVDGVPLPPKASRQLPAGSVVTLRTPGGGGWGPPP
>Mature_539_residues
MLRNLPLDRVVGGPVPARRRPAGCHAGGMDAVTLSVVSSALGGIAEEMGTLLVRSAYSSNIKERRDCSAAIFDADARMIA
QAAHVPVHLGAMYESVRVVAERGPLPGDVWVLNDPFSGGNHLPDVTLISPLAFDGEVVGYAATRAHHSDMGGMRPGSMPA
DSTEIFAEGLIIPPVRLVRAGRWEEDLLDLICANSRTPDLRRGDLRAQAAANGLAATRLAELARRHGTGLVLESFAEVLR
YGERRSRAVIARLPDGVHRVESELEGDGVDDRDIALRVAVTIEGDGITVDFTGTSPAVRGNVNCPRAVTRSACCFALRVL
LPDDVPTGDGTYAPLTVVTEPGSLVDAQRPSAVVAGNVETSQRIADTVLAALRLAVGAGPDVLAAPGQGTMNNLVIGGAT
WTYYETLGGGQGASARGRGPSGVHVGMTNTLNTPIEALELEYPMRVERYELADGTGGPGRHPGGDGLVRSVRVLEPATLS
VLTDRRRHAPGGVAGGGPGAVGHNDVDGVPLPPKASRQLPAGSVVTLRTPGGGGWGPPP

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=536, Percent_Identity=41.2313432835821, Blast_Score=317, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI133901900, Length=534, Percent_Identity=38.2022471910112, Blast_Score=321, Evalue=6e-88,
Organism=Caenorhabditis elegans, GI133901902, Length=514, Percent_Identity=36.9649805447471, Blast_Score=293, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6322634, Length=548, Percent_Identity=35.5839416058394, Blast_Score=311, Evalue=2e-85,
Organism=Drosophila melanogaster, GI45550492, Length=536, Percent_Identity=40.4850746268657, Blast_Score=322, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: 3.5.2.14

Molecular weight: Translated: 56030; Mature: 56030

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRNLPLDRVVGGPVPARRRPAGCHAGGMDAVTLSVVSSALGGIAEEMGTLLVRSAYSSN
CCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IKERRDCSAAIFDADARMIAQAAHVPVHLGAMYESVRVVAERGPLPGDVWVLNDPFSGGN
HHHHHCCCCEEECCHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
HLPDVTLISPLAFDGEVVGYAATRAHHSDMGGMRPGSMPADSTEIFAEGLIIPPVRLVRA
CCCCEEEECCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHC
GRWEEDLLDLICANSRTPDLRRGDLRAQAAANGLAATRLAELARRHGTGLVLESFAEVLR
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
YGERRSRAVIARLPDGVHRVESELEGDGVDDRDIALRVAVTIEGDGITVDFTGTSPAVRG
HCCHHCCEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCEEC
NVNCPRAVTRSACCFALRVLLPDDVPTGDGTYAPLTVVTEPGSLVDAQRPSAVVAGNVET
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCHH
SQRIADTVLAALRLAVGAGPDVLAAPGQGTMNNLVIGGATWTYYETLGGGQGASARGRGP
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCEEEEHHHCCCCCCCCCCCCCC
SGVHVGMTNTLNTPIEALELEYPMRVERYELADGTGGPGRHPGGDGLVRSVRVLEPATLS
CCEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHH
VLTDRRRHAPGGVAGGGPGAVGHNDVDGVPLPPKASRQLPAGSVVTLRTPGGGGWGPPP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLRNLPLDRVVGGPVPARRRPAGCHAGGMDAVTLSVVSSALGGIAEEMGTLLVRSAYSSN
CCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IKERRDCSAAIFDADARMIAQAAHVPVHLGAMYESVRVVAERGPLPGDVWVLNDPFSGGN
HHHHHCCCCEEECCHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
HLPDVTLISPLAFDGEVVGYAATRAHHSDMGGMRPGSMPADSTEIFAEGLIIPPVRLVRA
CCCCEEEECCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHC
GRWEEDLLDLICANSRTPDLRRGDLRAQAAANGLAATRLAELARRHGTGLVLESFAEVLR
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
YGERRSRAVIARLPDGVHRVESELEGDGVDDRDIALRVAVTIEGDGITVDFTGTSPAVRG
HCCHHCCEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCEEC
NVNCPRAVTRSACCFALRVLLPDDVPTGDGTYAPLTVVTEPGSLVDAQRPSAVVAGNVET
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCHH
SQRIADTVLAALRLAVGAGPDVLAAPGQGTMNNLVIGGATWTYYETLGGGQGASARGRGP
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCEEEEHHHCCCCCCCCCCCCCC
SGVHVGMTNTLNTPIEALELEYPMRVERYELADGTGGPGRHPGGDGLVRSVRVLEPATLS
CCEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHH
VLTDRRRHAPGGVAGGGPGAVGHNDVDGVPLPPKASRQLPAGSVVTLRTPGGGGWGPPP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]