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The map label for this gene is hepT [H]

Identifier: 158317822

GI number: 158317822

Start: 7401046

End: 7402062

Strand: Reverse

Name: hepT [H]

Synonym: Franean1_6080

Alternate gene names: 158317822

Gene position: 7402062-7401046 (Counterclockwise)

Preceding gene: 158317823

Following gene: 158317818

Centisome position: 82.41

GC content: 72.07

Gene sequence:

>1017_bases
ATGAGCGCTATCGGGCTGGAAGTGATGGGGATCAGGGCCGACCCTGATCTCGAGAAGTCGATGCGGGTCGGGCTCGCCGC
GGTCGAGGAGATGCTGCGCGGATCCGTCCGCAGCGAGTTCTCCTTCGTGACCGAGGCGTCCCGGCACCTCGTCGACGCGG
GCGGCAAGCGGTTCCGACCTATGGTCGTACTGCTTGCCGCCCAGTTCGCCGATCCGGACGCGGCCGGTGTCGTGCCGGCG
GCCGTGGCGATCGAGCTGACCCATCTGTCGACGCTGTACCACGACGACGTGATGGACGAGGCCCCGCTGCGCCGCGGTGC
CGCGTCCGCGAACGCCCGGTGGACGAACACGGTCGCGATCCTCACCGGCGACTTCCTGTTCGCCCGCGCGTCCGAGATCA
CGGCCGACCTGGGGCCGGAGGCGACCCGCATCCTGGCACGCACGATCGCGACCCTCTGCGAGGGCCAGATCCGCGAGACC
GTCGGGGTCGGGCCGGGGCAGGACCCGATCGAGCACTACCTGCGGGTCATCACGGAGAAGACGGCTTCGCTGATCGCCAC
GTCCGCCCGCCTGGGCGCCATGCTCGCCGGCGCCGACCCGGTCACGACCGACGTCCTGGCCGCGTTCGGGGAGCGCTTCG
GGGTGGCCTTCCAGCTCTCCGACGACCTCATCGACGTGGCGTCACCGAGCGAGGACTCCGGCAAGACACCCGGGACGGAC
CTGCGCGAGGGCATCCCGACGCTGCCGGTGCTCTATGCCCTGCAGGGCGAGGACGCGGCGGCCCGCCGGCTGCGCGACCT
GCTCGGGGTGAACCCGCGCACGGAGGCCGGGGTCACCGAGTCCGGGGTCGTCGAGGCGTTGGAGCTGCTGCGCGAGCATC
CCGCGATGGACCGGGCCCGCGCCGAGCTCATCCGCTGGTCGAGCGAGGCCCGCGAGTGCCTGGCGCCGCTGCCCGACGGC
TCGGCCAAGACCGCGCTGGAGTCGCTGGCCGACTTCGTCATCGACCGCACGAGCTAG

Upstream 100 bases:

>100_bases
ATAGGTGCACTCATGACCCTGCTGTTGGGCGTGGCGCCGCAGCCGCTTCTCGACCTGGCGACCACCGCGGCGACCTCCGG
CTTCGTACGCTGATGGCGGT

Downstream 100 bases:

>100_bases
CCGGGCTCTACCCAGCCAGCCCTGGCCGGTGCGTGGCTGTCACCTGATCCCCTGCTGGCCCCCTGCCGGCCACCGCGCCG
TGCGGCGGCCGGCAGGGGGT

Product: polyprenyl synthetase

Products: NA

Alternate protein names: HEPPP synthase subunit 2 [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSAIGLEVMGIRADPDLEKSMRVGLAAVEEMLRGSVRSEFSFVTEASRHLVDAGGKRFRPMVVLLAAQFADPDAAGVVPA
AVAIELTHLSTLYHDDVMDEAPLRRGAASANARWTNTVAILTGDFLFARASEITADLGPEATRILARTIATLCEGQIRET
VGVGPGQDPIEHYLRVITEKTASLIATSARLGAMLAGADPVTTDVLAAFGERFGVAFQLSDDLIDVASPSEDSGKTPGTD
LREGIPTLPVLYALQGEDAAARRLRDLLGVNPRTEAGVTESGVVEALELLREHPAMDRARAELIRWSSEARECLAPLPDG
SAKTALESLADFVIDRTS

Sequences:

>Translated_338_residues
MSAIGLEVMGIRADPDLEKSMRVGLAAVEEMLRGSVRSEFSFVTEASRHLVDAGGKRFRPMVVLLAAQFADPDAAGVVPA
AVAIELTHLSTLYHDDVMDEAPLRRGAASANARWTNTVAILTGDFLFARASEITADLGPEATRILARTIATLCEGQIRET
VGVGPGQDPIEHYLRVITEKTASLIATSARLGAMLAGADPVTTDVLAAFGERFGVAFQLSDDLIDVASPSEDSGKTPGTD
LREGIPTLPVLYALQGEDAAARRLRDLLGVNPRTEAGVTESGVVEALELLREHPAMDRARAELIRWSSEARECLAPLPDG
SAKTALESLADFVIDRTS
>Mature_337_residues
SAIGLEVMGIRADPDLEKSMRVGLAAVEEMLRGSVRSEFSFVTEASRHLVDAGGKRFRPMVVLLAAQFADPDAAGVVPAA
VAIELTHLSTLYHDDVMDEAPLRRGAASANARWTNTVAILTGDFLFARASEITADLGPEATRILARTIATLCEGQIRETV
GVGPGQDPIEHYLRVITEKTASLIATSARLGAMLAGADPVTTDVLAAFGERFGVAFQLSDDLIDVASPSEDSGKTPGTDL
REGIPTLPVLYALQGEDAAARRLRDLLGVNPRTEAGVTESGVVEALELLREHPAMDRARAELIRWSSEARECLAPLPDGS
AKTALESLADFVIDRTS

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=239, Percent_Identity=34.3096234309623, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1789578, Length=314, Percent_Identity=32.8025477707006, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786623, Length=311, Percent_Identity=29.5819935691318, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17505681, Length=330, Percent_Identity=30.6060606060606, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319475, Length=312, Percent_Identity=30.7692307692308, Blast_Score=129, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24651612, Length=298, Percent_Identity=30.5369127516779, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 35956; Mature: 35825

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIGLEVMGIRADPDLEKSMRVGLAAVEEMLRGSVRSEFSFVTEASRHLVDAGGKRFRP
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
MVVLLAAQFADPDAAGVVPAAVAIELTHLSTLYHDDVMDEAPLRRGAASANARWTNTVAI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
LTGDFLFARASEITADLGPEATRILARTIATLCEGQIRETVGVGPGQDPIEHYLRVITEK
EECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TASLIATSARLGAMLAGADPVTTDVLAAFGERFGVAFQLSDDLIDVASPSEDSGKTPGTD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCCHHCCCCCCCCCCCCCCCH
LREGIPTLPVLYALQGEDAAARRLRDLLGVNPRTEAGVTESGVVEALELLREHPAMDRAR
HHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
AELIRWSSEARECLAPLPDGSAKTALESLADFVIDRTS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAIGLEVMGIRADPDLEKSMRVGLAAVEEMLRGSVRSEFSFVTEASRHLVDAGGKRFRP
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
MVVLLAAQFADPDAAGVVPAAVAIELTHLSTLYHDDVMDEAPLRRGAASANARWTNTVAI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
LTGDFLFARASEITADLGPEATRILARTIATLCEGQIRETVGVGPGQDPIEHYLRVITEK
EECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TASLIATSARLGAMLAGADPVTTDVLAAFGERFGVAFQLSDDLIDVASPSEDSGKTPGTD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCCHHCCCCCCCCCCCCCCCH
LREGIPTLPVLYALQGEDAAARRLRDLLGVNPRTEAGVTESGVVEALELLREHPAMDRAR
HHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
AELIRWSSEARECLAPLPDGSAKTALESLADFVIDRTS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7629164 [H]