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The map label for this gene is htpX2 [H]

Identifier: 158317817

GI number: 158317817

Start: 7392917

End: 7393789

Strand: Reverse

Name: htpX2 [H]

Synonym: Franean1_6075

Alternate gene names: 158317817

Gene position: 7393789-7392917 (Counterclockwise)

Preceding gene: 158317818

Following gene: 158317814

Centisome position: 82.32

GC content: 67.58

Gene sequence:

>873_bases
ATGCTTCATCGCAGTCTCAACGGGCTGAAGACGGCGCTTCTCCTCGGCGTTCTCTCGGCCGCGATCGTGTGGATCGGGTC
GCTCTTCGGCACGAGCGGCCTCGTCATCGCCGTCGTTCTCGCGCTCGCGATGAACGGATTCTCCTACTTCTACTCGGATC
GGATCGCCCTGCGGGCGATGCGGGCGTATCCGGTGAGCCAGGTTCAGCAGCCCCGGCTCTACGCGATCGTCCAGGAGCTC
GCCACCCGGGCGCGCATGCCGATGCCCAAGCTGTACCTGAGCCCCACATCGTCACCGAACGCCTTCGCGACCGGGCGAAA
CCCCCGTAACGCGGCCGTGTGCTGCACCGAGGGAATCATGGAGATCATGGATGACCGTGAGCTCCGTGGTGTCCTCGGGC
ATGAGCTGAGCCATGTCTACAACCGCGACATCCTCATCGCCTCGGTTGCGGGCGCGCTCGCGGGCATCATCGTTTATCTG
GCAAACATGCTGCAGTGGTTTGCCATTTTCGGCGGCGGTCGCGACGAGGACGGCCCCGGGGTACTGGAGATGCTGGCCCT
CATCGTCGTCGGCCCGATCGCCGCCACGATCATCCAGCTGGCGATCAGCCGGGCCCGCGAGTACCAGGCGGACGAATCCG
GGTCGACCCTCACCGGCGACCCGCTCGGCCTGGCCAGCGCCCTGCGCAAGTTGGATGCCGGCACGGCCGCCAGGCCGCTG
CCAGCCAACTCGCGGCTGGGCCCGGCCGCCGCGCTGATGATCGCGAACCCGTTCCGCGGCGGCGGCATCGGCCGGTTCTT
CTCGACCCACCCGCCGATCGCCGAGCGGATCGCCCGGTTGGAGCAGCGCGCCAGGATGAACCCGTATCGGTAA

Upstream 100 bases:

>100_bases
GGACGGCCGCGGGTGGGCGTGACCGCTGCCGGGAACAGGGAGCGTCGGCTCCTTCGTTGAAGCGAGTGCGACAGGTCGAC
AGGACGGATACGCGACAGCC

Downstream 100 bases:

>100_bases
CCCCATCCAATCCGCCTACTCCGTCCACCCTCAACCCCACCGCCACGGTTCCGCCCGGAGGAATCGGCTCCCGGTCGCTT
TGCCGGCCGGGAGCGGCGCG

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLHRSLNGLKTALLLGVLSAAIVWIGSLFGTSGLVIAVVLALAMNGFSYFYSDRIALRAMRAYPVSQVQQPRLYAIVQEL
ATRARMPMPKLYLSPTSSPNAFATGRNPRNAAVCCTEGIMEIMDDRELRGVLGHELSHVYNRDILIASVAGALAGIIVYL
ANMLQWFAIFGGGRDEDGPGVLEMLALIVVGPIAATIIQLAISRAREYQADESGSTLTGDPLGLASALRKLDAGTAARPL
PANSRLGPAAALMIANPFRGGGIGRFFSTHPPIAERIARLEQRARMNPYR

Sequences:

>Translated_290_residues
MLHRSLNGLKTALLLGVLSAAIVWIGSLFGTSGLVIAVVLALAMNGFSYFYSDRIALRAMRAYPVSQVQQPRLYAIVQEL
ATRARMPMPKLYLSPTSSPNAFATGRNPRNAAVCCTEGIMEIMDDRELRGVLGHELSHVYNRDILIASVAGALAGIIVYL
ANMLQWFAIFGGGRDEDGPGVLEMLALIVVGPIAATIIQLAISRAREYQADESGSTLTGDPLGLASALRKLDAGTAARPL
PANSRLGPAAALMIANPFRGGGIGRFFSTHPPIAERIARLEQRARMNPYR
>Mature_290_residues
MLHRSLNGLKTALLLGVLSAAIVWIGSLFGTSGLVIAVVLALAMNGFSYFYSDRIALRAMRAYPVSQVQQPRLYAIVQEL
ATRARMPMPKLYLSPTSSPNAFATGRNPRNAAVCCTEGIMEIMDDRELRGVLGHELSHVYNRDILIASVAGALAGIIVYL
ANMLQWFAIFGGGRDEDGPGVLEMLALIVVGPIAATIIQLAISRAREYQADESGSTLTGDPLGLASALRKLDAGTAARPL
PANSRLGPAAALMIANPFRGGGIGRFFSTHPPIAERIARLEQRARMNPYR

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=289, Percent_Identity=27.681660899654, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 31115; Mature: 31115

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHRSLNGLKTALLLGVLSAAIVWIGSLFGTSGLVIAVVLALAMNGFSYFYSDRIALRAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAYPVSQVQQPRLYAIVQELATRARMPMPKLYLSPTSSPNAFATGRNPRNAAVCCTEGIM
HHCCHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEECCCCCCCHHHHHHHHHH
EIMDDRELRGVLGHELSHVYNRDILIASVAGALAGIIVYLANMLQWFAIFGGGRDEDGPG
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VLEMLALIVVGPIAATIIQLAISRAREYQADESGSTLTGDPLGLASALRKLDAGTAARPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
PANSRLGPAAALMIANPFRGGGIGRFFSTHPPIAERIARLEQRARMNPYR
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLHRSLNGLKTALLLGVLSAAIVWIGSLFGTSGLVIAVVLALAMNGFSYFYSDRIALRAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAYPVSQVQQPRLYAIVQELATRARMPMPKLYLSPTSSPNAFATGRNPRNAAVCCTEGIM
HHCCHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEECCCCCCCHHHHHHHHHH
EIMDDRELRGVLGHELSHVYNRDILIASVAGALAGIIVYLANMLQWFAIFGGGRDEDGPG
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VLEMLALIVVGPIAATIIQLAISRAREYQADESGSTLTGDPLGLASALRKLDAGTAARPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
PANSRLGPAAALMIANPFRGGGIGRFFSTHPPIAERIARLEQRARMNPYR
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]