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The map label for this gene is azoR

Identifier: 158317746

GI number: 158317746

Start: 7323217

End: 7323852

Strand: Direct

Name: azoR

Synonym: Franean1_6004

Alternate gene names: 158317746

Gene position: 7323217-7323852 (Clockwise)

Preceding gene: 158317742

Following gene: 158317756

Centisome position: 81.53

GC content: 71.7

Gene sequence:

>636_bases
ATGCCCCACCTGCTGCACATCGACTCCAGCCTCGCCCCGGAGGGCTCCGTCTCCCGCGGAGTCGCCGAGGCCTACGCCGA
GTCCTGGCGCAAGCACCACCCGGACGGCACGCTGACCCACCGCGACCTGGCCACCAGCCCGCCGCCGCACCTGAACTGGG
CGCTGGTGTCCGGCGGCCAGACACCCCCCGAGCAGCGCACACCCGAGCAGGCCGAGGCCGTGAAGATCCGCGAGGAGTAC
CTCGAGGAGGTCGAGAGCGCCGACGAGTACGTGATCTCGGTGCCGATGTACAACTACGCCTACCCGTCGACGATCAAGGC
CTGGCTGGACCAGGTCATCGTCATGGGCCGCACGGCCGGCGGGACGGCCGGCGACGGCGTGCTGGCGGGCAGGAAGGTCA
CCGTCATCACCGCGCAGGGGGGCTCCTACGCCCCCGGCGCCCCCAAGGAGGGCTGGGACCACCAGGTCCCCTACCTGCGC
CACGCCTTCGAGGCACTCGGCGCCGACAACATCGAGTTCATCACCGTCGTGATGACGCTGTCGAAGGTGAACCCGGCGCT
CGCCGCGTTCACCGACGTGTTCGAGGCCTCCCGGACGGCCGCGGAGCAGACGGCCCGCGACCGCGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
ACACGGCGCCAGCGCCGGATCGGCCGGATCGGCACCCTCCCTCCCGCGGCGCGCGCCGAGACCGGCACCCGCCTCCCGAT
CGTGATCAAGGAGAGCTCCG

Downstream 100 bases:

>100_bases
GCGCCGCCCGGCCCGGGACCCGTGGCGGGTCCCGGGCCGGCGAAGGTGGTCAGAAGGCCGTCAGCGGGTGGAGACGTCAG
AGAGCGGAAACGGTCAGAGG

Product: NAD(P)H dehydrogenase (quinone)

Products: 4'-phosphopantetheine; apoprotein

Alternate protein names: Azo-dye reductase; FMN-dependent NADH-azo compound oxidoreductase

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MPHLLHIDSSLAPEGSVSRGVAEAYAESWRKHHPDGTLTHRDLATSPPPHLNWALVSGGQTPPEQRTPEQAEAVKIREEY
LEEVESADEYVISVPMYNYAYPSTIKAWLDQVIVMGRTAGGTAGDGVLAGRKVTVITAQGGSYAPGAPKEGWDHQVPYLR
HAFEALGADNIEFITVVMTLSKVNPALAAFTDVFEASRTAAEQTARDRAAA

Sequences:

>Translated_211_residues
MPHLLHIDSSLAPEGSVSRGVAEAYAESWRKHHPDGTLTHRDLATSPPPHLNWALVSGGQTPPEQRTPEQAEAVKIREEY
LEEVESADEYVISVPMYNYAYPSTIKAWLDQVIVMGRTAGGTAGDGVLAGRKVTVITAQGGSYAPGAPKEGWDHQVPYLR
HAFEALGADNIEFITVVMTLSKVNPALAAFTDVFEASRTAAEQTARDRAAA
>Mature_210_residues
PHLLHIDSSLAPEGSVSRGVAEAYAESWRKHHPDGTLTHRDLATSPPPHLNWALVSGGQTPPEQRTPEQAEAVKIREEYL
EEVESADEYVISVPMYNYAYPSTIKAWLDQVIVMGRTAGGTAGDGVLAGRKVTVITAQGGSYAPGAPKEGWDHQVPYLRH
AFEALGADNIEFITVVMTLSKVNPALAAFTDVFEASRTAAEQTARDRAAA

Specific function: Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity

COG id: COG1182

COG function: function code I; Acyl carrier protein phosphodiesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the azoreductase type 1 family

Homologues:

Organism=Escherichia coli, GI1787680, Length=176, Percent_Identity=31.25, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AZOR_FRASN (A8LAY7)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001510254.1
- ProteinModelPortal:   A8LAY7
- SMR:   A8LAY7
- GeneID:   5674325
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_6004
- HOGENOM:   HBG565834
- OMA:   SADEYVI
- ProtClustDB:   CLSK901850
- BioCyc:   FSP1855:FRANEAN1_6004-MONOMER
- HAMAP:   MF_01216
- InterPro:   IPR003680
- InterPro:   IPR023048

Pfam domain/function: PF02525 Flavodoxin_2

EC number: 3.1.4.14

Molecular weight: Translated: 22791; Mature: 22659

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHLLHIDSSLAPEGSVSRGVAEAYAESWRKHHPDGTLTHRDLATSPPPHLNWALVSGGQ
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCC
TPPEQRTPEQAEAVKIREEYLEEVESADEYVISVPMYNYAYPSTIKAWLDQVIVMGRTAG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCC
GTAGDGVLAGRKVTVITAQGGSYAPGAPKEGWDHQVPYLRHAFEALGADNIEFITVVMTL
CCCCCCEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
SKVNPALAAFTDVFEASRTAAEQTARDRAAA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PHLLHIDSSLAPEGSVSRGVAEAYAESWRKHHPDGTLTHRDLATSPPPHLNWALVSGGQ
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCC
TPPEQRTPEQAEAVKIREEYLEEVESADEYVISVPMYNYAYPSTIKAWLDQVIVMGRTAG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCC
GTAGDGVLAGRKVTVITAQGGSYAPGAPKEGWDHQVPYLRHAFEALGADNIEFITVVMTL
CCCCCCEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
SKVNPALAAFTDVFEASRTAAEQTARDRAAA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: [acyl-carrier protein]; H2O

Specific reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA