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The map label for this gene is aspS [H]

Identifier: 158317668

GI number: 158317668

Start: 7197079

End: 7198938

Strand: Direct

Name: aspS [H]

Synonym: Franean1_5926

Alternate gene names: 158317668

Gene position: 7197079-7198938 (Clockwise)

Preceding gene: 158317666

Following gene: 158317669

Centisome position: 80.13

GC content: 73.12

Gene sequence:

>1860_bases
ATGTCGACAGCCGCCAGCACGCCCGGAACGCACAGCACCGCGATGCGTACCCACCTGTGCGGTGATCTGGGGCTCGGCAA
CGCCGGCCAGCGGGTGACGGTCTGCGGGTGGGTCGCGCACCGCCGCCAGCACGGCCAGTCGCTGATGTTCGTCGACCTGC
GCGACCACTCGGGCCTGCTCCAGTGCGTCGTCGACGGCTCGGTCGACGCTCGCTCCGAGTACGTCCTGCGGATCACCGGC
ACCGTCACCGCCCGCCCGGAGGGCACCGTGAACCCGGCCCTGGCCACCGGCGAGGTCGAACTGACGGACTGCGCCGTCGA
GGTGCTCTCGGTCGCCGCGCCGCCGCCGTTCCCGCTCGACGACCGGGCCGACTCCGTCGAGGAGAGCACCCGGCTCACCT
ACCGGTACCTCGACCTGCGCCGCGACCGGATGCAGCGCAACCTGCGGACCCGCTCGGCGGTCCTCGGCGCGCTGCGCACC
GCGTTCGCCGACCGCGGGTTCGTCGAGGTGGAGACGCCGCTGCTGATGCCGTCGACGCCGGAGGGCGCGCGCGAGTTCGT
CGTCCCGTCCCGGCAGTTCCCGGGCAGCTTCTACGCGCTGCCGCAGTCGCCGCAGCTTTTCAAGCAGCTGCTGATGGTCG
GCGGGATGGACCGCTACTTCCAGCTCGCGCGCTGCCTGCGCGACGAGGACCTGCGCGCCGACCGGCAGTACGAGTTCACC
CAGCTCGACCTGGAGATGAGCTTCGTCGGCGTCGACGACATCCTCGATGTGGTCTCCGCGGCGGTGCTCTCGGCCGCCGC
CGCGGCCGCGGCGGGCTCCGGGCGCGCCGTGCCCGAGATCGAGCGGCTGACCTGGCACGACGCGATGAACCGGTTCGGGG
TCGACAAGCCCGACCTGCGGTTCGGGATGGAGCTCGTCGAGCTCACCGCGATCTTCGCCGACAGCGGCTTCAAGGCGTTC
GCCGGCGCCCCGGCGGTCAAGGGCATCCGGGTGCCGGGCGGGTCGGCCACGCACAACCGCAAGGCGCTCGACACCCTCAC
CGACCGCGCCAAGAAGCTGGGTGCGAAGGGCCTGGTGTGGATGCGCGTCGCCGCCGCCGGGGGGCTGGAGTCACCGGTCG
CGAAGTTCCTCTCCCCCGCGGAGCTCACCGGGATCGTCACGGCGACCGCGGCCGAGGAGGGCGACCTGCTGCTGCTCGTC
GCGGACGAGTGGGAGACCACCTGCGAGGTGCTCGGCCAGCTGCGCAACGACCTCGGGCGTCCGCCCGCCGGCGCGGGCGA
GCTGCGTTTCGCCTGGGTGGTCGACTTCCCCCTGTTCGTCGGCGTGGACGCGGCCACCGGGCGGCCGAAGCCGGGGCACC
ACCCGTTCACCCGGCCGCATCCCGACGACGTCGAGAAGATGGAGTCCGAGCCGCTGGCGGTGCGCAGCCTGGCCTACGAC
CTGGTGCTCAACGGGTGGGAGCTGGGCTCGGGGTCGATCCGGATCCACGAGAGCGAGCTGCAGCAGCGCGTCTTCGGGCT
GCTGGGCATCTCGCCGGAGGAGGCGAAGGCCCGGTTCGGGTTCTTCCTCACCCCGTTCGGGTACGGCGCCCCGCCGCACG
GTGGATTCGCGTTCGGTATCGACCGGCTTGTCGCCGTCCTCGCGGGCGAGGACAACATCCGTGAGGTCATCGCCTTCCCG
AAGACCCAGTCCGGGCTCGACCCGCTGACCGGCGCTCCCACGACGATCGACGAGCGGCAGCTCCGCGAGCTCGGTATCCG
CGTGGTCGCCCCCGCCGTGCCCGGTCCGGCGGCGCCCGCGAAGCCCGGCGGTCCGGCGGCGCCCACCGTTCCCGCCGCGC
CCGCCCGCCCGGCATCCTGA

Upstream 100 bases:

>100_bases
ACGTGACGCGGCTCCCGATCAGTCGCATCAGTCAAATCAGCTATTGGTGACATCAGCACTAGCGGTGACATCAGCAAGTG
GTGACACAGGACGGATGGCC

Downstream 100 bases:

>100_bases
CAGCGGCCGGGTTCCCCTGTCCCCGGCGCTGCGGAGAGATCCCGGTCAGTCACGCGGAAGTACTCGCCGCCACGAAAAGT
CAAACTAAGATAACTCTCAG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 619; Mature: 618

Protein sequence:

>619_residues
MSTAASTPGTHSTAMRTHLCGDLGLGNAGQRVTVCGWVAHRRQHGQSLMFVDLRDHSGLLQCVVDGSVDARSEYVLRITG
TVTARPEGTVNPALATGEVELTDCAVEVLSVAAPPPFPLDDRADSVEESTRLTYRYLDLRRDRMQRNLRTRSAVLGALRT
AFADRGFVEVETPLLMPSTPEGAREFVVPSRQFPGSFYALPQSPQLFKQLLMVGGMDRYFQLARCLRDEDLRADRQYEFT
QLDLEMSFVGVDDILDVVSAAVLSAAAAAAAGSGRAVPEIERLTWHDAMNRFGVDKPDLRFGMELVELTAIFADSGFKAF
AGAPAVKGIRVPGGSATHNRKALDTLTDRAKKLGAKGLVWMRVAAAGGLESPVAKFLSPAELTGIVTATAAEEGDLLLLV
ADEWETTCEVLGQLRNDLGRPPAGAGELRFAWVVDFPLFVGVDAATGRPKPGHHPFTRPHPDDVEKMESEPLAVRSLAYD
LVLNGWELGSGSIRIHESELQQRVFGLLGISPEEAKARFGFFLTPFGYGAPPHGGFAFGIDRLVAVLAGEDNIREVIAFP
KTQSGLDPLTGAPTTIDERQLRELGIRVVAPAVPGPAAPAKPGGPAAPTVPAAPARPAS

Sequences:

>Translated_619_residues
MSTAASTPGTHSTAMRTHLCGDLGLGNAGQRVTVCGWVAHRRQHGQSLMFVDLRDHSGLLQCVVDGSVDARSEYVLRITG
TVTARPEGTVNPALATGEVELTDCAVEVLSVAAPPPFPLDDRADSVEESTRLTYRYLDLRRDRMQRNLRTRSAVLGALRT
AFADRGFVEVETPLLMPSTPEGAREFVVPSRQFPGSFYALPQSPQLFKQLLMVGGMDRYFQLARCLRDEDLRADRQYEFT
QLDLEMSFVGVDDILDVVSAAVLSAAAAAAAGSGRAVPEIERLTWHDAMNRFGVDKPDLRFGMELVELTAIFADSGFKAF
AGAPAVKGIRVPGGSATHNRKALDTLTDRAKKLGAKGLVWMRVAAAGGLESPVAKFLSPAELTGIVTATAAEEGDLLLLV
ADEWETTCEVLGQLRNDLGRPPAGAGELRFAWVVDFPLFVGVDAATGRPKPGHHPFTRPHPDDVEKMESEPLAVRSLAYD
LVLNGWELGSGSIRIHESELQQRVFGLLGISPEEAKARFGFFLTPFGYGAPPHGGFAFGIDRLVAVLAGEDNIREVIAFP
KTQSGLDPLTGAPTTIDERQLRELGIRVVAPAVPGPAAPAKPGGPAAPTVPAAPARPAS
>Mature_618_residues
STAASTPGTHSTAMRTHLCGDLGLGNAGQRVTVCGWVAHRRQHGQSLMFVDLRDHSGLLQCVVDGSVDARSEYVLRITGT
VTARPEGTVNPALATGEVELTDCAVEVLSVAAPPPFPLDDRADSVEESTRLTYRYLDLRRDRMQRNLRTRSAVLGALRTA
FADRGFVEVETPLLMPSTPEGAREFVVPSRQFPGSFYALPQSPQLFKQLLMVGGMDRYFQLARCLRDEDLRADRQYEFTQ
LDLEMSFVGVDDILDVVSAAVLSAAAAAAAGSGRAVPEIERLTWHDAMNRFGVDKPDLRFGMELVELTAIFADSGFKAFA
GAPAVKGIRVPGGSATHNRKALDTLTDRAKKLGAKGLVWMRVAAAGGLESPVAKFLSPAELTGIVTATAAEEGDLLLLVA
DEWETTCEVLGQLRNDLGRPPAGAGELRFAWVVDFPLFVGVDAATGRPKPGHHPFTRPHPDDVEKMESEPLAVRSLAYDL
VLNGWELGSGSIRIHESELQQRVFGLLGISPEEAKARFGFFLTPFGYGAPPHGGFAFGIDRLVAVLAGEDNIREVIAFPK
TQSGLDPLTGAPTTIDERQLRELGIRVVAPAVPGPAAPAKPGGPAAPTVPAAPARPAS

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=614, Percent_Identity=38.9250814332248, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI4758762, Length=248, Percent_Identity=31.4516129032258, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI45439306, Length=250, Percent_Identity=29.6, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI5031815, Length=266, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI194272210, Length=256, Percent_Identity=25.78125, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI226491502, Length=250, Percent_Identity=27.6, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788173, Length=598, Percent_Identity=44.1471571906354, Blast_Score=476, Evalue=1e-135,
Organism=Escherichia coli, GI1789256, Length=291, Percent_Identity=26.4604810996564, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790571, Length=291, Percent_Identity=26.8041237113402, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32566633, Length=607, Percent_Identity=35.7495881383855, Blast_Score=324, Evalue=9e-89,
Organism=Caenorhabditis elegans, GI71984122, Length=246, Percent_Identity=31.7073170731707, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994340, Length=253, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17535927, Length=253, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17535925, Length=253, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551876, Length=257, Percent_Identity=28.4046692607004, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6325153, Length=617, Percent_Identity=32.5769854132901, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6321807, Length=317, Percent_Identity=26.4984227129338, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323011, Length=262, Percent_Identity=28.2442748091603, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320242, Length=149, Percent_Identity=29.5302013422819, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324256, Length=249, Percent_Identity=26.5060240963855, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584738, Length=637, Percent_Identity=38.3045525902669, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI19921528, Length=234, Percent_Identity=29.9145299145299, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640849, Length=258, Percent_Identity=27.5193798449612, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640851, Length=258, Percent_Identity=27.5193798449612, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17136276, Length=257, Percent_Identity=30.7392996108949, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 66321; Mature: 66190

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAASTPGTHSTAMRTHLCGDLGLGNAGQRVTVCGWVAHRRQHGQSLMFVDLRDHSGLL
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCEEEEEEECCCCCEE
QCVVDGSVDARSEYVLRITGTVTARPEGTVNPALATGEVELTDCAVEVLSVAAPPPFPLD
EEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCEECCCEEHHHHHHHHHHHCCCCCCCCC
DRADSVEESTRLTYRYLDLRRDRMQRNLRTRSAVLGALRTAFADRGFVEVETPLLMPSTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEECCCCC
EGAREFVVPSRQFPGSFYALPQSPQLFKQLLMVGGMDRYFQLARCLRDEDLRADRQYEFT
CCCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEE
QLDLEMSFVGVDDILDVVSAAVLSAAAAAAAGSGRAVPEIERLTWHDAMNRFGVDKPDLR
EEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
FGMELVELTAIFADSGFKAFAGAPAVKGIRVPGGSATHNRKALDTLTDRAKKLGAKGLVW
HHHHHHHHHHHHHCCCCHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
MRVAAAGGLESPVAKFLSPAELTGIVTATAAEEGDLLLLVADEWETTCEVLGQLRNDLGR
EEEECCCCCHHHHHHHCCCHHHHEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
PPAGAGELRFAWVVDFPLFVGVDAATGRPKPGHHPFTRPHPDDVEKMESEPLAVRSLAYD
CCCCCCCEEEEEEECCHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHH
LVLNGWELGSGSIRIHESELQQRVFGLLGISPEEAKARFGFFLTPFGYGAPPHGGFAFGI
HHCCCEEECCCEEEEEHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCCCCCCHHHHH
DRLVAVLAGEDNIREVIAFPKTQSGLDPLTGAPTTIDERQLRELGIRVVAPAVPGPAAPA
HHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCC
KPGGPAAPTVPAAPARPAS
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STAASTPGTHSTAMRTHLCGDLGLGNAGQRVTVCGWVAHRRQHGQSLMFVDLRDHSGLL
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCEEEEEEECCCCCEE
QCVVDGSVDARSEYVLRITGTVTARPEGTVNPALATGEVELTDCAVEVLSVAAPPPFPLD
EEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCEECCCEEHHHHHHHHHHHCCCCCCCCC
DRADSVEESTRLTYRYLDLRRDRMQRNLRTRSAVLGALRTAFADRGFVEVETPLLMPSTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEECCCCC
EGAREFVVPSRQFPGSFYALPQSPQLFKQLLMVGGMDRYFQLARCLRDEDLRADRQYEFT
CCCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEE
QLDLEMSFVGVDDILDVVSAAVLSAAAAAAAGSGRAVPEIERLTWHDAMNRFGVDKPDLR
EEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
FGMELVELTAIFADSGFKAFAGAPAVKGIRVPGGSATHNRKALDTLTDRAKKLGAKGLVW
HHHHHHHHHHHHHCCCCHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
MRVAAAGGLESPVAKFLSPAELTGIVTATAAEEGDLLLLVADEWETTCEVLGQLRNDLGR
EEEECCCCCHHHHHHHCCCHHHHEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
PPAGAGELRFAWVVDFPLFVGVDAATGRPKPGHHPFTRPHPDDVEKMESEPLAVRSLAYD
CCCCCCCEEEEEEECCHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHH
LVLNGWELGSGSIRIHESELQQRVFGLLGISPEEAKARFGFFLTPFGYGAPPHGGFAFGI
HHCCCEEECCCEEEEEHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCCCCCCHHHHH
DRLVAVLAGEDNIREVIAFPKTQSGLDPLTGAPTTIDERQLRELGIRVVAPAVPGPAAPA
HHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCC
KPGGPAAPTVPAAPARPAS
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]