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The map label for this gene is vgb [H]

Identifier: 158317561

GI number: 158317561

Start: 7059856

End: 7060674

Strand: Reverse

Name: vgb [H]

Synonym: Franean1_5817

Alternate gene names: 158317561

Gene position: 7060674-7059856 (Counterclockwise)

Preceding gene: 158317565

Following gene: 158317560

Centisome position: 78.61

GC content: 69.84

Gene sequence:

>819_bases
GTGGGTCACGATGGTCCACGCCGGGCAGATCGCGCGGCTGGCCCGAGACGGCCACCTCGACTCCTACCAGCTAACCCCGG
CCTCCTGCGGACCGTCGATTATCACCGAGGGTCCGGACGGCGCTATGTGGTTCACCCGCAACGGCGACCACCAGATCGGA
AGGATCGCCCTCGACGGCGAGACTACGTCCTTCCCCGTTCCCATCCTGGACAGCGGGCCCTTCGGCATCACGACCGGCCC
GGACGGCGCCCTGTGGTTCACCGAGATGAACAGCGACCGGATCGGGCGCATCACCACCGACGGCGCGATCACCGAGTACC
CGCTCCCGCAACCCAGGCCCTGCCGGCGGCGATCACCGCCGGAGTCGACCAGGCCGTCTGGTTCACCCTCAACCAGGCGA
ACGCGATCGGCCGCATCACCCCTTCCGGGCAGATCACGCTTCACCCGCTGCCCACCCCGGGTGCCGCCCCGGTCGGGATC
TGTGGGACCGCCGACGGCGCAATCTGGTTCGTCGAGATCGCCGCCGGTCAGATCGGCCGGATCCGAACCGATGGACGGAT
CGAGGAGTTCTCCCTTCCCGACCGGGACGCCCGGCCCCACGCGATCATCGCCGACCCGACCGCCGGCGTCTGCTGGTTCT
CCGCGTGGGCCGCGGGCCGGATCGGCCACATCACCCCGGACGGAAAGATCGACGAATACGATCTGCCGACACCATCAAGC
GAGCCGCACGGCCTCACCGTCGCCGGGGACGGCACTGTCCATGTTGCCCTCGAAACCGGCGGCCTCGCGCGCTTGGAGCG
GGCTGCCGTCGACCCCTGA

Upstream 100 bases:

>100_bases
CCGTGATTCCCCACCATGGAAGCGCCATGATCCACGAAATGCGGATAGCAGGCCCTGATGCTGGCCCCTACGACCTGACT
CTCGGACCCGACGGGGCGCT

Downstream 100 bases:

>100_bases
AAACTGACCCCTGTCGACTACGGCCACAGTGGACCAAAGATCGACTACGCCACGGTGAACTGGCGCGGTTACGTTCACGC
CTGACGTGTGTCTCCGCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: Streptogramin B lyase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MGHDGPRRADRAAGPRRPPRLLPANPGLLRTVDYHRGSGRRYVVHPQRRPPDRKDRPRRRDYVLPRSHPGQRALRHHDRP
GRRPVVHRDEQRPDRAHHHRRRDHRVPAPATQALPAAITAGVDQAVWFTLNQANAIGRITPSGQITLHPLPTPGAAPVGI
CGTADGAIWFVEIAAGQIGRIRTDGRIEEFSLPDRDARPHAIIADPTAGVCWFSAWAAGRIGHITPDGKIDEYDLPTPSS
EPHGLTVAGDGTVHVALETGGLARLERAAVDP

Sequences:

>Translated_272_residues
MGHDGPRRADRAAGPRRPPRLLPANPGLLRTVDYHRGSGRRYVVHPQRRPPDRKDRPRRRDYVLPRSHPGQRALRHHDRP
GRRPVVHRDEQRPDRAHHHRRRDHRVPAPATQALPAAITAGVDQAVWFTLNQANAIGRITPSGQITLHPLPTPGAAPVGI
CGTADGAIWFVEIAAGQIGRIRTDGRIEEFSLPDRDARPHAIIADPTAGVCWFSAWAAGRIGHITPDGKIDEYDLPTPSS
EPHGLTVAGDGTVHVALETGGLARLERAAVDP
>Mature_271_residues
GHDGPRRADRAAGPRRPPRLLPANPGLLRTVDYHRGSGRRYVVHPQRRPPDRKDRPRRRDYVLPRSHPGQRALRHHDRPG
RRPVVHRDEQRPDRAHHHRRRDHRVPAPATQALPAAITAGVDQAVWFTLNQANAIGRITPSGQITLHPLPTPGAAPVGIC
GTADGAIWFVEIAAGQIGRIRTDGRIEEFSLPDRDARPHAIIADPTAGVCWFSAWAAGRIGHITPDGKIDEYDLPTPSSE
PHGLTVAGDGTVHVALETGGLARLERAAVDP

Specific function: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid [H]

COG id: COG4257

COG function: function code V; Streptogramin lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the vgb family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011217 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 29818; Mature: 29687

Theoretical pI: Translated: 11.49; Mature: 11.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHDGPRRADRAAGPRRPPRLLPANPGLLRTVDYHRGSGRRYVVHPQRRPPDRKDRPRRR
CCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCHH
DYVLPRSHPGQRALRHHDRPGRRPVVHRDEQRPDRAHHHRRRDHRVPAPATQALPAAITA
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHC
GVDQAVWFTLNQANAIGRITPSGQITLHPLPTPGAAPVGICGTADGAIWFVEIAAGQIGR
CCCCEEEEEEECCCCEEEECCCCCEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCE
IRTDGRIEEFSLPDRDARPHAIIADPTAGVCWFSAWAAGRIGHITPDGKIDEYDLPTPSS
EECCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCCCCCCCCC
EPHGLTVAGDGTVHVALETGGLARLERAAVDP
CCCEEEEECCCEEEEEEECCCHHHHHHHCCCC
>Mature Secondary Structure 
GHDGPRRADRAAGPRRPPRLLPANPGLLRTVDYHRGSGRRYVVHPQRRPPDRKDRPRRR
CCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCHH
DYVLPRSHPGQRALRHHDRPGRRPVVHRDEQRPDRAHHHRRRDHRVPAPATQALPAAITA
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHC
GVDQAVWFTLNQANAIGRITPSGQITLHPLPTPGAAPVGICGTADGAIWFVEIAAGQIGR
CCCCEEEEEEECCCCEEEECCCCCEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCE
IRTDGRIEEFSLPDRDARPHAIIADPTAGVCWFSAWAAGRIGHITPDGKIDEYDLPTPSS
EECCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCCCCCCCCC
EPHGLTVAGDGTVHVALETGGLARLERAAVDP
CCCEEEEECCCEEEEEEECCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA