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The map label for this gene is pfpI [H]

Identifier: 158317334

GI number: 158317334

Start: 6770272

End: 6770859

Strand: Reverse

Name: pfpI [H]

Synonym: Franean1_5584

Alternate gene names: 158317334

Gene position: 6770859-6770272 (Counterclockwise)

Preceding gene: 158317335

Following gene: 158317333

Centisome position: 75.38

GC content: 71.26

Gene sequence:

>588_bases
ATGACGAATCTCGGTCATGACGCGGGCCGCCGTGCGGACACCGCGCGCCAGGTCGCGTTCCTCACCGCGAAGGAAGGCGT
TGAGCAGGTCGAGTTGACCGGACCCTGGCGGGCCGTGCGCGACGCCGGGTTCACCCCGGTCCTGGTCTCGACGGAGGAGG
GGACGGTCCAGGCGTTCCACCATCTCGATCGCGCCGACACCTTCCCGGTGGACGCGACGGTCACCGGCGCCGACCCGGGT
GGCTTCGACGCGTTGGTGCTTCCCGGCGGGGTAGCCAATCCGGACACCCTGCGCTGGCAGCCGGGCGTCGTGCCGTTCGT
CCGGACCTTCTTCGACCGTGGTCTTCCAGTGGCCGTGATCTGCCACGGCCCGTGGACGTTGATCGAGGCCGACGTCGTCC
GGGGCCGGCGGGTCACGAGCTGGCCGAGCCTGCGGACGGACCTGCGCAACGCCGGTGCCACCTGGGTCGACGACGAGGTC
GTGATCTGCCGGTCGGGGCCCAATCCGCTGATCAGCAGCCGGCGGCCGGGTGATCTGCCGGCTTTCGAGTCCGCGCTCGT
CGGTGAGCTGGCGCCGGCGCACGTCTGA

Upstream 100 bases:

>100_bases
GGCAGCGGCCCCCGGCGGGTGACGGCCTCGGCACCACGGACAGGCTGCCCGGGACCGGGGCCCAGGCCGCTGAACGGATC
TCAGCGAGGGAGTGAACAGC

Downstream 100 bases:

>100_bases
ACGCGGCCCGGCGGGCTCCGCCGCGCGGCGGGCACGGCGACCGTCACCCCGGCCGTGGGCCGCGCGGCGCCGAGCTGGAC
GTAGCCTGGGTGGTCGAGGA

Product: PfpI family intracellular peptidase

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MTNLGHDAGRRADTARQVAFLTAKEGVEQVELTGPWRAVRDAGFTPVLVSTEEGTVQAFHHLDRADTFPVDATVTGADPG
GFDALVLPGGVANPDTLRWQPGVVPFVRTFFDRGLPVAVICHGPWTLIEADVVRGRRVTSWPSLRTDLRNAGATWVDDEV
VICRSGPNPLISSRRPGDLPAFESALVGELAPAHV

Sequences:

>Translated_195_residues
MTNLGHDAGRRADTARQVAFLTAKEGVEQVELTGPWRAVRDAGFTPVLVSTEEGTVQAFHHLDRADTFPVDATVTGADPG
GFDALVLPGGVANPDTLRWQPGVVPFVRTFFDRGLPVAVICHGPWTLIEADVVRGRRVTSWPSLRTDLRNAGATWVDDEV
VICRSGPNPLISSRRPGDLPAFESALVGELAPAHV
>Mature_194_residues
TNLGHDAGRRADTARQVAFLTAKEGVEQVELTGPWRAVRDAGFTPVLVSTEEGTVQAFHHLDRADTFPVDATVTGADPGG
FDALVLPGGVANPDTLRWQPGVVPFVRTFFDRGLPVAVICHGPWTLIEADVVRGRRVTSWPSLRTDLRNAGATWVDDEVV
ICRSGPNPLISSRRPGDLPAFESALVGELAPAHV

Specific function: Highly stable protease. Although the physiological function is unclear it is the dominant protease in P.furiosus [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=168, Percent_Identity=38.6904761904762, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20938; Mature: 20807

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLGHDAGRRADTARQVAFLTAKEGVEQVELTGPWRAVRDAGFTPVLVSTEEGTVQAFH
CCCCCCCCCCCHHHHHHHEEEEHHCCCEEEEECCCHHHHHHCCCCEEEEECCCCHHHHHH
HLDRADTFPVDATVTGADPGGFDALVLPGGVANPDTLRWQPGVVPFVRTFFDRGLPVAVI
HHCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHCCCCEEEE
CHGPWTLIEADVVRGRRVTSWPSLRTDLRNAGATWVDDEVVICRSGPNPLISSRRPGDLP
ECCCCEEEEHHHHCCCCCCCCCHHHHHHHHCCCCEECCCEEEECCCCCCCCCCCCCCCCC
AFESALVGELAPAHV
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
TNLGHDAGRRADTARQVAFLTAKEGVEQVELTGPWRAVRDAGFTPVLVSTEEGTVQAFH
CCCCCCCCCCHHHHHHHEEEEHHCCCEEEEECCCHHHHHHCCCCEEEEECCCCHHHHHH
HLDRADTFPVDATVTGADPGGFDALVLPGGVANPDTLRWQPGVVPFVRTFFDRGLPVAVI
HHCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHCCCCEEEE
CHGPWTLIEADVVRGRRVTSWPSLRTDLRNAGATWVDDEVVICRSGPNPLISSRRPGDLP
ECCCCEEEEHHHHCCCCCCCCCHHHHHHHHCCCCEECCCEEEECCCCCCCCCCCCCCCCC
AFESALVGELAPAHV
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626329 [H]