Click here to switch to the map view.

The map label for this gene is mmgC [H]

Identifier: 158317323

GI number: 158317323

Start: 6753656

End: 6754834

Strand: Direct

Name: mmgC [H]

Synonym: Franean1_5573

Alternate gene names: 158317323

Gene position: 6753656-6754834 (Clockwise)

Preceding gene: 158317322

Following gene: 158317326

Centisome position: 75.19

GC content: 72.77

Gene sequence:

>1179_bases
GTGAGTCTGGTGTTCTCCGACGAACAGGAGGAGCTGCGCCGCACGGTGCGGTCGTTCCTCGAGCACGCCTCCCCCGAGTC
GGAGGTGCGCCGCCTGATGGAGTCCGACGACGGGTACGACCCGGCCATCTGGCGGCAGATGGCCACCCAGCTCGGGCTGC
AGGGGCTACACGTCCCCGAGGAGTACGGCGGCGCCGGCTTCGGGTACGTGGAGCTCGGCATCGTGCTGGAGGAAATGGGC
GCACGGCTGCTGTGCGCGCCCTTCCTCGCCTCCGCCGTGCTCGCCACCGGCGCGCTGCTCGCGGTGGACGACGCCTTGGC
CCGCAAGGAGCTGCTCCCCGGGCTCGTCAGCGGGACGACCATCGGGACACTGGCGTTCGCCGGCCCCACGGGCCGTCCGG
AACCCGCCGGTTCCGGTGGGCTCGGGCCGCAGGGCGGAACCGGTGCCGAAGGCGGGCACCACGGGCTGCTCGCGGCCCGG
GCTGCCAGCGGGTACACGTTGCGCGGCACCCGGCATTTCGTCCTGGACGGGGCGCTGGCCGATCTCATCCTCGTCACGGC
GTGGGCCGAGGGCGGGCTCTCCCTGTTCGCCGTCCCCGGCGACGCGGCGGGCCTGACCCGGTCCCGGTTGCCCGTGATGG
ACCTGACCCGCAAACAGGCCGATCTCACGTTCAGTGACACCCCGGCCCGGTTGATCGGCGCCGAGGGCGACGCCGGCCCG
GTGATCGACCAGGTGCTCCGGCTCGCCTGCGTCGCGCTGGCGAACGAGAGCGCCGGCGGCGCCCGGACCGTCCTCGAGCA
GGCCGTGCGGCACGCGAAGGACCGCCTGCAGTTCGGCCGTCCGATCGGGTCGTTCCAGGCCGTGAAGCACAAGTGCGCCG
ACATGCTGGTCGCGGTCGAGGGCTCGAAGTCGGTCGCCTATCACGCGGCCCAGGTCGCCGCCGGGAACAGCGCCGCCGGG
AACACCGACCGGCTGGCCCGCGCCGCCTCCATGGCGAAGGCGTACGTCGGGGAGGCGTACTTCTCGGCCGCGGCGGACAA
CATCCAGATCCACGGCGGGATCGGATTCACCTGGGAGCACTCCGCGCACCTGTACTTCAAACGCGCGAAGACGTCCGAGC
TGCTCTTCGGCGACCCGGTCCACCACCGCGGCCTGCTGGCCGACCGCCTCCGGGTCTGA

Upstream 100 bases:

>100_bases
CGGCGAACGGGTGCTCGGCCTGCCCGGCGACATCCGCGTCGACAAGGATGTGTCCTGGCGTGACATACCGCGCTGACCGC
CCGTCGCCGAGAGGAGCTCC

Downstream 100 bases:

>100_bases
AATGCCGCCGGTCGGCCCGCCGGGCCGACCTGAATTTCAGCCGCTACGACCGCGCCGCGGCTACCAGGCCGGGAAGTCGC
GCTTGCGGATCAGGCAGTGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSLVFSDEQEELRRTVRSFLEHASPESEVRRLMESDDGYDPAIWRQMATQLGLQGLHVPEEYGGAGFGYVELGIVLEEMG
ARLLCAPFLASAVLATGALLAVDDALARKELLPGLVSGTTIGTLAFAGPTGRPEPAGSGGLGPQGGTGAEGGHHGLLAAR
AASGYTLRGTRHFVLDGALADLILVTAWAEGGLSLFAVPGDAAGLTRSRLPVMDLTRKQADLTFSDTPARLIGAEGDAGP
VIDQVLRLACVALANESAGGARTVLEQAVRHAKDRLQFGRPIGSFQAVKHKCADMLVAVEGSKSVAYHAAQVAAGNSAAG
NTDRLARAASMAKAYVGEAYFSAAADNIQIHGGIGFTWEHSAHLYFKRAKTSELLFGDPVHHRGLLADRLRV

Sequences:

>Translated_392_residues
MSLVFSDEQEELRRTVRSFLEHASPESEVRRLMESDDGYDPAIWRQMATQLGLQGLHVPEEYGGAGFGYVELGIVLEEMG
ARLLCAPFLASAVLATGALLAVDDALARKELLPGLVSGTTIGTLAFAGPTGRPEPAGSGGLGPQGGTGAEGGHHGLLAAR
AASGYTLRGTRHFVLDGALADLILVTAWAEGGLSLFAVPGDAAGLTRSRLPVMDLTRKQADLTFSDTPARLIGAEGDAGP
VIDQVLRLACVALANESAGGARTVLEQAVRHAKDRLQFGRPIGSFQAVKHKCADMLVAVEGSKSVAYHAAQVAAGNSAAG
NTDRLARAASMAKAYVGEAYFSAAADNIQIHGGIGFTWEHSAHLYFKRAKTSELLFGDPVHHRGLLADRLRV
>Mature_391_residues
SLVFSDEQEELRRTVRSFLEHASPESEVRRLMESDDGYDPAIWRQMATQLGLQGLHVPEEYGGAGFGYVELGIVLEEMGA
RLLCAPFLASAVLATGALLAVDDALARKELLPGLVSGTTIGTLAFAGPTGRPEPAGSGGLGPQGGTGAEGGHHGLLAARA
ASGYTLRGTRHFVLDGALADLILVTAWAEGGLSLFAVPGDAAGLTRSRLPVMDLTRKQADLTFSDTPARLIGAEGDAGPV
IDQVLRLACVALANESAGGARTVLEQAVRHAKDRLQFGRPIGSFQAVKHKCADMLVAVEGSKSVAYHAAQVAAGNSAAGN
TDRLARAASMAKAYVGEAYFSAAADNIQIHGGIGFTWEHSAHLYFKRAKTSELLFGDPVHHRGLLADRLRV

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=350, Percent_Identity=27.4285714285714, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI226958412, Length=392, Percent_Identity=27.5510204081633, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4501857, Length=372, Percent_Identity=26.0752688172043, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI226958414, Length=352, Percent_Identity=26.7045454545455, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4501859, Length=379, Percent_Identity=24.2744063324538, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4557235, Length=378, Percent_Identity=25.1322751322751, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI76496475, Length=378, Percent_Identity=25.1322751322751, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI187960098, Length=404, Percent_Identity=24.2574257425743, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4557231, Length=404, Percent_Identity=24.2574257425743, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21361497, Length=375, Percent_Identity=23.2, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7656849, Length=421, Percent_Identity=20.6650831353919, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=23.4828496042216, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=387, Percent_Identity=26.0981912144703, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17570075, Length=409, Percent_Identity=25.1833740831296, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=377, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=25.3926701570681, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=369, Percent_Identity=24.6612466124661, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=409, Percent_Identity=23.960880195599, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=388, Percent_Identity=20.1030927835052, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=413, Percent_Identity=20.3389830508475, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356377, Length=410, Percent_Identity=24.1463414634146, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24646207, Length=409, Percent_Identity=25.9168704156479, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281363737, Length=377, Percent_Identity=23.342175066313, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355753, Length=403, Percent_Identity=24.8138957816377, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666513, Length=384, Percent_Identity=21.875, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=410, Percent_Identity=23.1707317073171, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41098; Mature: 40967

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVFSDEQEELRRTVRSFLEHASPESEVRRLMESDDGYDPAIWRQMATQLGLQGLHVPE
CCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCH
EYGGAGFGYVELGIVLEEMGARLLCAPFLASAVLATGALLAVDDALARKELLPGLVSGTT
HHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHCCCC
IGTLAFAGPTGRPEPAGSGGLGPQGGTGAEGGHHGLLAARAASGYTLRGTRHFVLDGALA
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCEEEEEHHHHH
DLILVTAWAEGGLSLFAVPGDAAGLTRSRLPVMDLTRKQADLTFSDTPARLIGAEGDAGP
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCEECCCCHHEEECCCCCCH
VIDQVLRLACVALANESAGGARTVLEQAVRHAKDRLQFGRPIGSFQAVKHKCADMLVAVE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEC
GSKSVAYHAAQVAAGNSAAGNTDRLARAASMAKAYVGEAYFSAAADNIQIHGGIGFTWEH
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEC
SAHLYFKRAKTSELLFGDPVHHRGLLADRLRV
CCEEEEEECCCCCCEECCCHHHCCHHHHHHCC
>Mature Secondary Structure 
SLVFSDEQEELRRTVRSFLEHASPESEVRRLMESDDGYDPAIWRQMATQLGLQGLHVPE
CCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCH
EYGGAGFGYVELGIVLEEMGARLLCAPFLASAVLATGALLAVDDALARKELLPGLVSGTT
HHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHCCCC
IGTLAFAGPTGRPEPAGSGGLGPQGGTGAEGGHHGLLAARAASGYTLRGTRHFVLDGALA
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCEEEEEHHHHH
DLILVTAWAEGGLSLFAVPGDAAGLTRSRLPVMDLTRKQADLTFSDTPARLIGAEGDAGP
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCEECCCCHHEEECCCCCCH
VIDQVLRLACVALANESAGGARTVLEQAVRHAKDRLQFGRPIGSFQAVKHKCADMLVAVE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEC
GSKSVAYHAAQVAAGNSAAGNTDRLARAASMAKAYVGEAYFSAAADNIQIHGGIGFTWEH
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEC
SAHLYFKRAKTSELLFGDPVHHRGLLADRLRV
CCEEEEEECCCCCCEECCCHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]