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The map label for this gene is crp [C]

Identifier: 158317259

GI number: 158317259

Start: 6670433

End: 6671173

Strand: Reverse

Name: crp [C]

Synonym: Franean1_5506

Alternate gene names: 158317259

Gene position: 6671173-6670433 (Counterclockwise)

Preceding gene: 158317260

Following gene: 158317258

Centisome position: 74.27

GC content: 74.09

Gene sequence:

>741_bases
ATGGTTCGGGAGATCGGCCGGACCGGTCCGGAGCAACAGGGCCCGCGGCGGCGCGACTGGCCGTCGACCACCCTGCTCGG
GCGGCTGCCCGAACAGACCCGGGCGGCATTCGTCGGCCTGGGCCCCTACCGTGAGTACGCCAGCGAGGAGATCGTCCTGC
GGGAGGGCGACGGCACCAACTTCGTCGTGCTCCTGCTGAACGGGTGGGTCAAGGTCACCGCCTCCACCGAGAACGGCGGC
TTCGCCCTGCTCGCCATCCGCCACGGCGGCGACCTCGTCGGCGAGCAGGCCGGCCTGGACGGCGAGCCCCGGTCGGCGAC
GGTCACCGCGGCCGGGGCGGTGCTGGCGAAGGTGATTCCGCTGGAGGCGTTCCTCGCCTTCCTGCGGTCCCATCCCGACG
CGGGCCCTCCTGTGCTGCAGTCCGTCAGCGCCAAGCTGCGCAACGCGACCCGGCGCCGCGTCGAGTTCGGCGGGTGCTCG
GTAGCCGTCCGGCTGGCCCGCGTGATCGTCGAGCTCGAACGCGCCTACGGGGCCGACGCGACGGACGGCCCGGGGCGGCG
GGTCCAGATCGCCCTCACCCAGCCCGAGCTCGCCGCGCTCGTCGGCGCCGCCGAGCCGACGGTGCACAAGGTACTGCGCG
AGCTGCGCCAGCAGGGAGTCGTCGATACCCGCTACCGCTCCATCGTGATCCGCGACGTCGAGGCCCTGTACCGGGCCGCC
GGGACGACGCGCCCCCGCTGA

Upstream 100 bases:

>100_bases
ACGGGAACGGCCGTGATGATATCAACCGGTACATCGGGCAATTCGTGGATCATCGGTCGGGCTCCGGCATGGGCGGCACC
CGGCAGCAAGGGGGCGGATC

Downstream 100 bases:

>100_bases
TCGTCGTCGCTCGGACAATCCCATCGCATGACGATGTGTTCCGTGCCCACAGCGTGAACAGTTGCCTCCGACGGACCGTG
ACCATCGGAGGCTGTGCGTG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Cyclic AMP Receptor Protein; CAMP-Dependent Transcriptional Regulator; Catabolite Gene Activator; Nitrite And Nitric Oxide Reductase Regulator; Transcription Regulator Crp Family; Transcriptional Regulatory Protein; Regulatory Protein; Response Regulator Receiver; Transcriptional Regulator Vfr; Transcriptional Regulator Crp; CrP/Fnr Family Transcriptional Regulator; Transcription Regulator; Catabolite Protein Activator; Global Nitrogen Regulator NtcA; CAMP-Regulatory Protein; Transcriptional Regulator MrpC; Anaerobic Regulatory Protein; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MVREIGRTGPEQQGPRRRDWPSTTLLGRLPEQTRAAFVGLGPYREYASEEIVLREGDGTNFVVLLLNGWVKVTASTENGG
FALLAIRHGGDLVGEQAGLDGEPRSATVTAAGAVLAKVIPLEAFLAFLRSHPDAGPPVLQSVSAKLRNATRRRVEFGGCS
VAVRLARVIVELERAYGADATDGPGRRVQIALTQPELAALVGAAEPTVHKVLRELRQQGVVDTRYRSIVIRDVEALYRAA
GTTRPR

Sequences:

>Translated_246_residues
MVREIGRTGPEQQGPRRRDWPSTTLLGRLPEQTRAAFVGLGPYREYASEEIVLREGDGTNFVVLLLNGWVKVTASTENGG
FALLAIRHGGDLVGEQAGLDGEPRSATVTAAGAVLAKVIPLEAFLAFLRSHPDAGPPVLQSVSAKLRNATRRRVEFGGCS
VAVRLARVIVELERAYGADATDGPGRRVQIALTQPELAALVGAAEPTVHKVLRELRQQGVVDTRYRSIVIRDVEALYRAA
GTTRPR
>Mature_246_residues
MVREIGRTGPEQQGPRRRDWPSTTLLGRLPEQTRAAFVGLGPYREYASEEIVLREGDGTNFVVLLLNGWVKVTASTENGG
FALLAIRHGGDLVGEQAGLDGEPRSATVTAAGAVLAKVIPLEAFLAFLRSHPDAGPPVLQSVSAKLRNATRRRVEFGGCS
VAVRLARVIVELERAYGADATDGPGRRVQIALTQPELAALVGAAEPTVHKVLRELRQQGVVDTRYRSIVIRDVEALYRAA
GTTRPR

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789756, Length=196, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26549; Mature: 26549

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVREIGRTGPEQQGPRRRDWPSTTLLGRLPEQTRAAFVGLGPYREYASEEIVLREGDGTN
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHEEEECCHHHHHCCCEEEEEECCCCE
FVVLLLNGWVKVTASTENGGFALLAIRHGGDLVGEQAGLDGEPRSATVTAAGAVLAKVIP
EEEEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHH
LEAFLAFLRSHPDAGPPVLQSVSAKLRNATRRRVEFGGCSVAVRLARVIVELERAYGADA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
TDGPGRRVQIALTQPELAALVGAAEPTVHKVLRELRQQGVVDTRYRSIVIRDVEALYRAA
CCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
GTTRPR
CCCCCC
>Mature Secondary Structure
MVREIGRTGPEQQGPRRRDWPSTTLLGRLPEQTRAAFVGLGPYREYASEEIVLREGDGTN
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHEEEECCHHHHHCCCEEEEEECCCCE
FVVLLLNGWVKVTASTENGGFALLAIRHGGDLVGEQAGLDGEPRSATVTAAGAVLAKVIP
EEEEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHH
LEAFLAFLRSHPDAGPPVLQSVSAKLRNATRRRVEFGGCSVAVRLARVIVELERAYGADA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
TDGPGRRVQIALTQPELAALVGAAEPTVHKVLRELRQQGVVDTRYRSIVIRDVEALYRAA
CCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
GTTRPR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA