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The map label for this gene is btuE [C]

Identifier: 158317238

GI number: 158317238

Start: 6637703

End: 6638239

Strand: Reverse

Name: btuE [C]

Synonym: Franean1_5485

Alternate gene names: 158317238

Gene position: 6638239-6637703 (Counterclockwise)

Preceding gene: 158317239

Following gene: 158317236

Centisome position: 73.91

GC content: 67.97

Gene sequence:

>537_bases
ATGACTGTCCATGACTTCACCGTCGAGGCGACGGACGGCACCTCCCGATCCCTGCGCGACTACGCCGGCAAGACGCTGCT
GATCGTCAACGTCGCCAGCAAGTGCGGCCTGACCCCGCAGTACGAGGGGCTGGAGGCGCTCTACCGCGACCTGAAGGGGC
GGGGGCTGGAGATCCTCGGCTTCCCCTGCAACCAGTTCGGCGGCCAGGAGCCGGGCACCGACGCCGAGATCCAGGAGTTC
TGCTCGACGAACTTCGACGTCACCTTCCCCGTCTTCAGCAAGATCGAGGTGAACGGCCCCGGCGCGGCCCCGCTGTACGA
CTACCTGCGCTCGGAGGCCCCCGGCGACTTCGGCCCGGAGTCGGGCTTCCTCTACGAGCACATCAAGCGCTCGCGGCCCG
AGGCGATCGGTACCGACGAGGTGAAGTGGAACTTCACCAAGTTCCTGGTGGACGGCGAGGGCAAGGTCGTCCGCCGCTTC
GAGCCCACCGTCACCCCGGACGAGCTCCGCGGCGAGCTCGACACCTCCCTGGCCTGA

Upstream 100 bases:

>100_bases
GCTGTGTCCGGTCCTGCCCGGCCGGCTCCCGCTACGCGTCGGCGTCCCCGCCGCCGGACCTGCGGTCGTCGGGTCCGCAC
CACCGAGAGCTAGGTCGATC

Downstream 100 bases:

>100_bases
CGGGAGCGCTGTCGCTGACCCGGTAGCGCTGTAGCTGTCCGCCGCCCGGCAGACCGCCGGGCGGCGGACACGCGTGGCGG
TCAGTGGCTCGGGCGGACCT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MTVHDFTVEATDGTSRSLRDYAGKTLLIVNVASKCGLTPQYEGLEALYRDLKGRGLEILGFPCNQFGGQEPGTDAEIQEF
CSTNFDVTFPVFSKIEVNGPGAAPLYDYLRSEAPGDFGPESGFLYEHIKRSRPEAIGTDEVKWNFTKFLVDGEGKVVRRF
EPTVTPDELRGELDTSLA

Sequences:

>Translated_178_residues
MTVHDFTVEATDGTSRSLRDYAGKTLLIVNVASKCGLTPQYEGLEALYRDLKGRGLEILGFPCNQFGGQEPGTDAEIQEF
CSTNFDVTFPVFSKIEVNGPGAAPLYDYLRSEAPGDFGPESGFLYEHIKRSRPEAIGTDEVKWNFTKFLVDGEGKVVRRF
EPTVTPDELRGELDTSLA
>Mature_177_residues
TVHDFTVEATDGTSRSLRDYAGKTLLIVNVASKCGLTPQYEGLEALYRDLKGRGLEILGFPCNQFGGQEPGTDAEIQEFC
STNFDVTFPVFSKIEVNGPGAAPLYDYLRSEAPGDFGPESGFLYEHIKRSRPEAIGTDEVKWNFTKFLVDGEGKVVRRFE
PTVTPDELRGELDTSLA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=171, Percent_Identity=40.3508771929825, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI75709200, Length=173, Percent_Identity=37.5722543352601, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI90903240, Length=166, Percent_Identity=38.5542168674699, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI192455698, Length=173, Percent_Identity=32.9479768786127, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI4557629, Length=182, Percent_Identity=34.6153846153846, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI90903238, Length=148, Percent_Identity=37.8378378378378, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI6006001, Length=178, Percent_Identity=36.5168539325843, Blast_Score=97, Evalue=6e-21,
Organism=Homo sapiens, GI33186887, Length=168, Percent_Identity=34.5238095238095, Blast_Score=94, Evalue=5e-20,
Organism=Homo sapiens, GI41406084, Length=166, Percent_Identity=37.9518072289157, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI32967607, Length=168, Percent_Identity=31.547619047619, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1788003, Length=163, Percent_Identity=52.1472392638037, Blast_Score=170, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17506887, Length=177, Percent_Identity=41.8079096045198, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17535473, Length=177, Percent_Identity=41.8079096045198, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI193210707, Length=177, Percent_Identity=38.4180790960452, Blast_Score=115, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI71993584, Length=180, Percent_Identity=33.8888888888889, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17550320, Length=172, Percent_Identity=30.8139534883721, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI193209493, Length=173, Percent_Identity=30.0578034682081, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193210709, Length=74, Percent_Identity=45.945945945946, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71993573, Length=98, Percent_Identity=33.6734693877551, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=180, Percent_Identity=45.5555555555556, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322228, Length=155, Percent_Identity=47.0967741935484, Blast_Score=148, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6322826, Length=166, Percent_Identity=39.7590361445783, Blast_Score=126, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24656772, Length=179, Percent_Identity=41.340782122905, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24656767, Length=179, Percent_Identity=41.340782122905, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24656777, Length=179, Percent_Identity=41.340782122905, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI85726443, Length=179, Percent_Identity=36.8715083798883, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 19652; Mature: 19521

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHDFTVEATDGTSRSLRDYAGKTLLIVNVASKCGLTPQYEGLEALYRDLKGRGLEILG
CCCEEEEEEECCCCCHHHHHHCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHCCCCEEEEE
FPCNQFGGQEPGTDAEIQEFCSTNFDVTFPVFSKIEVNGPGAAPLYDYLRSEAPGDFGPE
CCHHHCCCCCCCCCHHHHHHHCCCCCEEECEEEEEEECCCCCCHHHHHHHHCCCCCCCCC
SGFLYEHIKRSRPEAIGTDEVKWNFTKFLVDGEGKVVRRFEPTVTPDELRGELDTSLA
CCHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCHHHHHCCHHCCCC
>Mature Secondary Structure 
TVHDFTVEATDGTSRSLRDYAGKTLLIVNVASKCGLTPQYEGLEALYRDLKGRGLEILG
CCEEEEEEECCCCCHHHHHHCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHCCCCEEEEE
FPCNQFGGQEPGTDAEIQEFCSTNFDVTFPVFSKIEVNGPGAAPLYDYLRSEAPGDFGPE
CCHHHCCCCCCCCCHHHHHHHCCCCCEEECEEEEEEECCCCCCHHHHHHHHCCCCCCCCC
SGFLYEHIKRSRPEAIGTDEVKWNFTKFLVDGEGKVVRRFEPTVTPDELRGELDTSLA
CCHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]