Click here to switch to the map view.

The map label for this gene is ubiE [H]

Identifier: 158316988

GI number: 158316988

Start: 6282170

End: 6283228

Strand: Direct

Name: ubiE [H]

Synonym: Franean1_5232

Alternate gene names: 158316988

Gene position: 6282170-6283228 (Clockwise)

Preceding gene: 158316983

Following gene: 158316989

Centisome position: 69.94

GC content: 78.66

Gene sequence:

>1059_bases
GTGTGGATGCCCGACGACAGTTCCGCGCCACCGCTGCCGGAGGCGATGACCGCCGAACAGGTCCGCCGCTGGGACGAGGT
CCTCGACCGGATCCGTGTGCTGCTGCCGGCCGGCGCGGCACGCGTGCTGGTCGAGGGTGCCGACGGCCGGAGGGCCGCCG
CGGTCGCCGACCGGCTGGCCGCGGCGGTGCGCGGGGCCGGCCGGCCGTGCGTCCGGCCGGCGGCCCTCAAGACGGCAGCC
CCCGAGACGACGACGGCCGCGCGGCCCGGCGAGACGGTGCTGCTCGCGCACAGCTCCGACCGGCCCGCCGACCGCACGTC
GACAGCCTGGGACCTGGTCGTCGAGCTGCGCACCCGCGCTGACCGCGACGACGATCCCGATCGGCCCGCGGACGTCGTCG
TCGACCTGCACGATCCGGCGTGGCCGGTGATCCGCCGGGTCGCGGAGCGGCTCGCGGCCGACGACGGCTGGCACGTCACC
GAGAGCCGGGCGTTCTTCGCCGTACGCGCCGCCACCTGGGACACCCGCTTCGGCGACGACACTCCCGCCTACACCGCGGC
GGTGGCCGAGCTGGGCCTGCCGACGGGGGCGACCGTCCTCGACGTCGGCTGCGGCACCGGCCGGGCGCTGCCCGTGCTGC
GCGCGGCCGTCGGCCCGGCCGGCACGGTGCTCGGGCTGGATGTCACCCCCGAGATGCTCGCCGTGGCCCGGGAACACGGC
CGGGCGGGGCATGCCGATCTCCTCCTCGGCGACGCCCGCCGCCTGCCCGTGCGGACCGGCGCGGTTGACGCGGTGTTCGC
CGCCGGGCTGGTCACCCACCTCCCCGACCTGCCGGCCGGGCTTGCCGAGCTGGCCCGGGTCAGCCGCCCCGGCGGCCGGC
TGGCGATCTTCCATCCGTCTGGCCGGGCGGCGCTCGCCGCCCGGCACGGGCGCGTGCTGCGCCCCGACGAGCCGCTGGCG
GCGGACCGGCTCGGCCCCCTGCTCGCCGGCTCCGGCTGGCGGCTCGACGGCTACGACGACCCGCCGCACCGCTTCCTCGC
ACTGGCCTCCCGCCGCTGA

Upstream 100 bases:

>100_bases
CCCAACACCCACCGACGCATCCTTCGGGCTCACGACCCCTGTGTGGTCATGGCCTTCGGCCGCTGGCAGCCGCCACCGTG
CCTGCCGGCTCGCCCATGAT

Downstream 100 bases:

>100_bases
CACCAGCCACGCACCGGCGCTGACACCGGCGGCGCAGGCAGGTGTCACGGGCGCGCGCGGGCGTCGGCTTCGTGACGTAG
CGACGCGTGCGTCGCGGATA

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MWMPDDSSAPPLPEAMTAEQVRRWDEVLDRIRVLLPAGAARVLVEGADGRRAAAVADRLAAAVRGAGRPCVRPAALKTAA
PETTTAARPGETVLLAHSSDRPADRTSTAWDLVVELRTRADRDDDPDRPADVVVDLHDPAWPVIRRVAERLAADDGWHVT
ESRAFFAVRAATWDTRFGDDTPAYTAAVAELGLPTGATVLDVGCGTGRALPVLRAAVGPAGTVLGLDVTPEMLAVAREHG
RAGHADLLLGDARRLPVRTGAVDAVFAAGLVTHLPDLPAGLAELARVSRPGGRLAIFHPSGRAALAARHGRVLRPDEPLA
ADRLGPLLAGSGWRLDGYDDPPHRFLALASRR

Sequences:

>Translated_352_residues
MWMPDDSSAPPLPEAMTAEQVRRWDEVLDRIRVLLPAGAARVLVEGADGRRAAAVADRLAAAVRGAGRPCVRPAALKTAA
PETTTAARPGETVLLAHSSDRPADRTSTAWDLVVELRTRADRDDDPDRPADVVVDLHDPAWPVIRRVAERLAADDGWHVT
ESRAFFAVRAATWDTRFGDDTPAYTAAVAELGLPTGATVLDVGCGTGRALPVLRAAVGPAGTVLGLDVTPEMLAVAREHG
RAGHADLLLGDARRLPVRTGAVDAVFAAGLVTHLPDLPAGLAELARVSRPGGRLAIFHPSGRAALAARHGRVLRPDEPLA
ADRLGPLLAGSGWRLDGYDDPPHRFLALASRR
>Mature_352_residues
MWMPDDSSAPPLPEAMTAEQVRRWDEVLDRIRVLLPAGAARVLVEGADGRRAAAVADRLAAAVRGAGRPCVRPAALKTAA
PETTTAARPGETVLLAHSSDRPADRTSTAWDLVVELRTRADRDDDPDRPADVVVDLHDPAWPVIRRVAERLAADDGWHVT
ESRAFFAVRAATWDTRFGDDTPAYTAAVAELGLPTGATVLDVGCGTGRALPVLRAAVGPAGTVLGLDVTPEMLAVAREHG
RAGHADLLLGDARRLPVRTGAVDAVFAAGLVTHLPDLPAGLAELARVSRPGGRLAIFHPSGRAALAARHGRVLRPDEPLA
ADRLGPLLAGSGWRLDGYDDPPHRFLALASRR

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014122
- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 37255; Mature: 37255

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWMPDDSSAPPLPEAMTAEQVRRWDEVLDRIRVLLPAGAARVLVEGADGRRAAAVADRLA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
AAVRGAGRPCVRPAALKTAAPETTTAARPGETVLLAHSSDRPADRTSTAWDLVVELRTRA
HHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHC
DRDDDPDRPADVVVDLHDPAWPVIRRVAERLAADDGWHVTESRAFFAVRAATWDTRFGDD
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEEECCCCCCCC
TPAYTAAVAELGLPTGATVLDVGCGTGRALPVLRAAVGPAGTVLGLDVTPEMLAVAREHG
CCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHC
RAGHADLLLGDARRLPVRTGAVDAVFAAGLVTHLPDLPAGLAELARVSRPGGRLAIFHPS
CCCCCEEEECCCCCCCEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCC
GRAALAARHGRVLRPDEPLAADRLGPLLAGSGWRLDGYDDPPHRFLALASRR
CCEEHHHHCCCCCCCCCCCCHHHHCHHHCCCCCCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MWMPDDSSAPPLPEAMTAEQVRRWDEVLDRIRVLLPAGAARVLVEGADGRRAAAVADRLA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
AAVRGAGRPCVRPAALKTAAPETTTAARPGETVLLAHSSDRPADRTSTAWDLVVELRTRA
HHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHC
DRDDDPDRPADVVVDLHDPAWPVIRRVAERLAADDGWHVTESRAFFAVRAATWDTRFGDD
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEEECCCCCCCC
TPAYTAAVAELGLPTGATVLDVGCGTGRALPVLRAAVGPAGTVLGLDVTPEMLAVAREHG
CCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHC
RAGHADLLLGDARRLPVRTGAVDAVFAAGLVTHLPDLPAGLAELARVSRPGGRLAIFHPS
CCCCCEEEECCCCCCCEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCC
GRAALAARHGRVLRPDEPLAADRLGPLLAGSGWRLDGYDDPPHRFLALASRR
CCEEHHHHCCCCCCCCCCCCHHHHCHHHCCCCCCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA