| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is bacC [H]
Identifier: 158316984
GI number: 158316984
Start: 6278551
End: 6279423
Strand: Reverse
Name: bacC [H]
Synonym: Franean1_5228
Alternate gene names: 158316984
Gene position: 6279423-6278551 (Counterclockwise)
Preceding gene: 158316985
Following gene: 158316982
Centisome position: 69.91
GC content: 73.54
Gene sequence:
>873_bases ATGCCCGACTTATTGGAGGACCGCGTCGTCGTGGTCACCGGCGGCGCCAGCGGGATCGGCCGCGCGAGCGTCCTGCGCTT CCTCGCCGCCGGCGCGCGTGTGGTCTTCGGCGATGTGAACGGCGCGACCGCCCAGCGGCTGCTCGACGAGGTCGCCGACC CCGCCCGGCTCCATTTCGAGCGGGCGGACGTGGCCGACGAGGCGGAGGTCGCCGCGCTCGTCGCCGCGGCCGTCGAGCGG TTCGGGCGCCTTGACGTCATGTTCAACAACGCCGGGGTCGGCGGGGCGTTCGGCCCGCTCACCGACATCGACGTCGCCGA CTGGGACCGCACCTTCGGCGTGATCAGCCGTGGGATGTTCCTCGGGACGAAGCACGCCGCCCGGGCGATGATCGCCCAGG GCGGCGGCGGGTCGATCATCAACAACTCCTCGGTCGCCGGAGTCGGCGGCGGTGGCGGCCCGACCGCGTACTCCGCGGCG AAGGCCGCGGTCATCAACTTCACCTGCAACGCGGCCGTGGAACTGGCGGCCCACCGCATCCGGGTCAACGCGATCTGCCC CGGTCTCGTCGACACGCCGCTGGTGATGGGGCGCGACGAGGCGGCCATCCGGGCCCGGATGGCGACCTTCCAGCCCTGGC CCGACCTGGGCCGGCCCGAGGACATCGCCGGCATCGTGCTCTTCCTCGCCGGTCCGGACAGCGCCTTCCTGACCGGGGAG GCGATCCGGGTCGACGGCGGGATGGTCGCCTGGGGCCCGCGGATGACCGACACCTCCGACCCCCGGGGCGTGACCCGCCG GTTCACGGGCTTCACCGAGGGCTCGACCGGCCGTCCACTGACCAAGCGCCCCCTGGACGGCGCCGGTACCTGA
Upstream 100 bases:
>100_bases CCCGACCGAGCCCGGGAAGGTGGACCACCGTGGCCGCTGACCTGCCCGAAGTCTCCCGGGACGGGGACCGGCGGTGTGAC CCGGCGGTACGTTACCGGTC
Downstream 100 bases:
>100_bases GGCCGGGCGGCGTGCTCCCGCCCGGGGGCGCGCTCCTGCCGCAGCACGGGCTTCCGCCGCGGGGTGGGCTTCGGTCAGAG ACCGAAGGCCCCGCCCTCGA
Product: short-chain dehydrogenase/reductase SDR
Products: 3alpha12alpha-dihydroxy-oxobeta-cholanate; NADH [C]
Alternate protein names: NA
Number of amino acids: Translated: 290; Mature: 289
Protein sequence:
>290_residues MPDLLEDRVVVVTGGASGIGRASVLRFLAAGARVVFGDVNGATAQRLLDEVADPARLHFERADVADEAEVAALVAAAVER FGRLDVMFNNAGVGGAFGPLTDIDVADWDRTFGVISRGMFLGTKHAARAMIAQGGGGSIINNSSVAGVGGGGGPTAYSAA KAAVINFTCNAAVELAAHRIRVNAICPGLVDTPLVMGRDEAAIRARMATFQPWPDLGRPEDIAGIVLFLAGPDSAFLTGE AIRVDGGMVAWGPRMTDTSDPRGVTRRFTGFTEGSTGRPLTKRPLDGAGT
Sequences:
>Translated_290_residues MPDLLEDRVVVVTGGASGIGRASVLRFLAAGARVVFGDVNGATAQRLLDEVADPARLHFERADVADEAEVAALVAAAVER FGRLDVMFNNAGVGGAFGPLTDIDVADWDRTFGVISRGMFLGTKHAARAMIAQGGGGSIINNSSVAGVGGGGGPTAYSAA KAAVINFTCNAAVELAAHRIRVNAICPGLVDTPLVMGRDEAAIRARMATFQPWPDLGRPEDIAGIVLFLAGPDSAFLTGE AIRVDGGMVAWGPRMTDTSDPRGVTRRFTGFTEGSTGRPLTKRPLDGAGT >Mature_289_residues PDLLEDRVVVVTGGASGIGRASVLRFLAAGARVVFGDVNGATAQRLLDEVADPARLHFERADVADEAEVAALVAAAVERF GRLDVMFNNAGVGGAFGPLTDIDVADWDRTFGVISRGMFLGTKHAARAMIAQGGGGSIINNSSVAGVGGGGGPTAYSAAK AAVINFTCNAAVELAAHRIRVNAICPGLVDTPLVMGRDEAAIRARMATFQPWPDLGRPEDIAGIVLFLAGPDSAFLTGEA IRVDGGMVAWGPRMTDTSDPRGVTRRFTGFTEGSTGRPLTKRPLDGAGT
Specific function: Part of the bacABCDE operon responsible for the biosynthesis of bacilysin [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=36.4341085271318, Blast_Score=128, Evalue=5e-30, Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=33.0708661417323, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=35.3413654618474, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=35.0253807106599, Blast_Score=107, Evalue=2e-23, Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=30.3501945525292, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI4758504, Length=251, Percent_Identity=34.6613545816733, Blast_Score=98, Evalue=1e-20, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=31.8367346938775, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=34.3023255813954, Blast_Score=89, Evalue=6e-18, Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=31.496062992126, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=30.5555555555556, Blast_Score=85, Evalue=9e-17, Organism=Homo sapiens, GI4504505, Length=242, Percent_Identity=32.2314049586777, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=31.2775330396476, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=29.9212598425197, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI83715985, Length=251, Percent_Identity=32.6693227091633, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI10190704, Length=265, Percent_Identity=29.811320754717, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=31.9796954314721, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=31.0526315789474, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=27.4678111587983, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=32.7868852459016, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=32.2834645669291, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=34.5098039215686, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=32.5301204819277, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=33.4677419354839, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=32.3886639676113, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=29.3436293436293, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=29.6, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=29.9180327868852, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=32.0158102766798, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.8461538461538, Blast_Score=89, Evalue=5e-19, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=30.2197802197802, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=31.5352697095436, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1787526, Length=242, Percent_Identity=27.6859504132231, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1788891, Length=264, Percent_Identity=28.7878787878788, Blast_Score=61, Evalue=1e-10, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=35.5102040816327, Blast_Score=127, Evalue=5e-30, Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=33.7254901960784, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=31.640625, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=31.3492063492063, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=34.2741935483871, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=33.4645669291339, Blast_Score=111, Evalue=6e-25, Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=32.0610687022901, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=32.5757575757576, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=30.7086614173228, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=32.1705426356589, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=30.4832713754647, Blast_Score=104, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=31.5589353612167, Blast_Score=104, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=31.25, Blast_Score=104, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=31.3432835820896, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=31.1538461538462, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=31.6602316602317, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=31.2977099236641, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=31.3207547169811, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=27.037037037037, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=32.8, Blast_Score=91, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17560332, Length=274, Percent_Identity=30.6569343065693, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17551412, Length=276, Percent_Identity=29.3478260869565, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=30.0751879699248, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=29.6296296296296, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=30.9278350515464, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=26.5384615384615, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=24.7422680412371, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=27.2030651340996, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193203117, Length=235, Percent_Identity=25.9574468085106, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=26.9035532994924, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193203115, Length=236, Percent_Identity=26.6949152542373, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=25.390625, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=241, Percent_Identity=29.4605809128631, Blast_Score=86, Evalue=9e-18, Organism=Saccharomyces cerevisiae, GI6324126, Length=277, Percent_Identity=29.2418772563177, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=204, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=5e-13, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=36.4372469635627, Blast_Score=132, Evalue=4e-31, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=33.984375, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=33.0769230769231, Blast_Score=119, Evalue=3e-27, Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=34.2205323193916, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=31.1284046692607, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=32.1138211382114, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=31.3725490196078, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=31.3008130081301, Blast_Score=86, Evalue=4e-17, Organism=Drosophila melanogaster, GI18859837, Length=188, Percent_Identity=35.6382978723404, Blast_Score=81, Evalue=8e-16, Organism=Drosophila melanogaster, GI24644337, Length=198, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24656154, Length=209, Percent_Identity=30.622009569378, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI19922628, Length=209, Percent_Identity=30.622009569378, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=32.8282828282828, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=32.8282828282828, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24581726, Length=207, Percent_Identity=28.0193236714976, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI28571387, Length=211, Percent_Identity=27.9620853080569, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.159 [C]
Molecular weight: Translated: 29932; Mature: 29801
Theoretical pI: Translated: 5.39; Mature: 5.39
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPDLLEDRVVVVTGGASGIGRASVLRFLAAGARVVFGDVNGATAQRLLDEVADPARLHFE CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCHHHEEEH RADVADEAEVAALVAAAVERFGRLDVMFNNAGVGGAFGPLTDIDVADWDRTFGVISRGMF HCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHH LGTKHAARAMIAQGGGGSIINNSSVAGVGGGGGPTAYSAAKAAVINFTCNAAVELAAHRI CCCHHHHHHHEECCCCCCEECCCCEEECCCCCCCHHHHHHCEEEEEEECHHHHHHHHHEE RVNAICPGLVDTPLVMGRDEAAIRARMATFQPWPDLGRPEDIAGIVLFLAGPDSAFLTGE EEEEECCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEECC AIRVDGGMVAWGPRMTDTSDPRGVTRRFTGFTEGSTGRPLTKRPLDGAGT EEEECCCEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure PDLLEDRVVVVTGGASGIGRASVLRFLAAGARVVFGDVNGATAQRLLDEVADPARLHFE CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCHHHEEEH RADVADEAEVAALVAAAVERFGRLDVMFNNAGVGGAFGPLTDIDVADWDRTFGVISRGMF HCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHH LGTKHAARAMIAQGGGGSIINNSSVAGVGGGGGPTAYSAAKAAVINFTCNAAVELAAHRI CCCHHHHHHHEECCCCCCEECCCCEEECCCCCCCHHHHHHCEEEEEEECHHHHHHHHHEE RVNAICPGLVDTPLVMGRDEAAIRARMATFQPWPDLGRPEDIAGIVLFLAGPDSAFLTGE EEEEECCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEECC AIRVDGGMVAWGPRMTDTSDPRGVTRRFTGFTEGSTGRPLTKRPLDGAGT EEEECCCEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: 2-Mercaptoethanol; Dithiothreitol; NAD+; NADH [C]
Metal ions: CaCl2; KCl; MnCl2; NaCl [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.8 {cholic} 0.085 {glycochenodeoxycholic} 0.24 {taurochenodeoxycholic} 1 {glycocholic} 0.06 {chenodeoxycholic} [C]
Substrates: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate!; NAD [C]
Specific reaction: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate! + NAD+ = 3alpha12alpha-dihydroxy-oxobeta-cholanate + NADH [C]
General reaction: Redox reaction [C]
Inhibitor: Ascorbicacid; BaCl2; CoCl2; CuCl2; EDTA; FeCl3; HgCl2; MgCl2; NH4Cl; Potassiumoxalate; Sodiumcitrate; Sodiumlaurylsulfate; Sodiumperchlorate; Sodiumperiodate; Sodiumpersulfate; TritonX-100; Tween; ZnCl2 [C]
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA