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The map label for this gene is rfbD [C]

Identifier: 158316959

GI number: 158316959

Start: 6246799

End: 6247836

Strand: Reverse

Name: rfbD [C]

Synonym: Franean1_5203

Alternate gene names: 158316959

Gene position: 6247836-6246799 (Counterclockwise)

Preceding gene: 158316965

Following gene: 158316958

Centisome position: 69.56

GC content: 73.41

Gene sequence:

>1038_bases
ATGCGTGTACTGGTCCTCGGCGGCGACGGCATGCTCGGCGGTGAGCTGGTCCGCCGGCTGGTCCGCGACCATGACGTCAC
CGCCACCGTCAGGGCCACCGCACCGTCCTGCCCGCCACCCGCCGACCGGGTGCTCAGCGGCGTGGACGTCCGCCGCCGCG
ACACCATGGTCGACGCGTTCGCCGCGGTGCGGCCGGACGCCGTCGTGAACGCCGTCAGCCTGGTCGGGCGGCGCGCGGAG
GGACGTGCCGAGCTGTCGGCGATCGAGGTCAACGCCCTTTTCCCGCATCGCCTCGCGCGCCTGTGCCAGGCCGCCGGGGC
GCGACTGGTGCACGTATCGACCGACTGCGTGTTCTCCGGCCGCCTGGGTGACTACCACGAGGAGGATGTGCCCGACCCGG
TGGACGTCCACGGGATGACCAAGCTGCTCGGCGAGGTGACCGAGCCGGGCACGCTCACGCTGCGGACGTCCGTCGTCGGC
CTGGAGGCGGTACCGGCGGCCTCGGGGCTCGTCGAGGGGTTCCTGGCGGCGAAGGGTGAGATCCCGGCCTCGCGCCGGGT
CGTCCACAGCGCTCTGACCACCGCCGAGTTCGCGCGCTTCGTCCACCTCGTGCTCGTGGGGCACCCGGACCTGACCGGGA
TCTGGCATCTCGCGTCCGAGCCGATCAGCCGGTTCGACCTGCTCACCATGCTCGCCGACCGGCTCGGCCGGCGGGACGTC
AAGATCGTCCCGAGCGACGGCGAGGCCCGCAACCGGGCGCTGTCCGCGCGCCGGCTGTGGTCGGAGACCGGCTACCTGCC
GCCCGGGTGGCCGGCGATGGTCGACGAGCTGGCGACCGCGATCGAACGGCGTGACATCGAAGGCTCCTCCCGGCGTCTCC
CGGCACCTCGTCCCGGCGGACCGGAGGCTCCCGCGCCGCCCTCACCTCCCCGAACGGAGTGCACGCCGATGCCTGACAGG
AACCTCGACGAACACGGCTCCGGGAACCGGCCGCCGCATCAGCCCTGGTCGGCCGAGCCGGTCGATCCGCTCCGGTAG

Upstream 100 bases:

>100_bases
AGGGGCGGCGGCCGGGCGCCGGACACCCGAGCACCACGAGTCCGGGCATCACGAGCGGACGGCCCACCCCGACCGGACCC
CGGTCTCGAAGGAGCGCTAG

Downstream 100 bases:

>100_bases
AAGGGACAGCGGCGTGTCGAGAACGAGAGGCGACAGAGACGACCACACCGGCGCCCGGCAACACGGGGGCGACGCCGAGC
TCACGCGGACGGGTTTCTTC

Product: dTDP-4-dehydrorhamnose reductase

Products: dTDP-4-dehydro-6-deoxy-L-mannose; NADPH; H+

Alternate protein names: Carbohydrate Oxidoreductase; Reductase; NAD-Dependent Epimerase/Dehydratase; LPS Biosynthesis Related Reductase; TDP-4-Keto-L-Rhamnose Reductase.; Sugar Oxidoreductase; NAD Dependent Epimerase/Dehydratase

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRVLVLGGDGMLGGELVRRLVRDHDVTATVRATAPSCPPPADRVLSGVDVRRRDTMVDAFAAVRPDAVVNAVSLVGRRAE
GRAELSAIEVNALFPHRLARLCQAAGARLVHVSTDCVFSGRLGDYHEEDVPDPVDVHGMTKLLGEVTEPGTLTLRTSVVG
LEAVPAASGLVEGFLAAKGEIPASRRVVHSALTTAEFARFVHLVLVGHPDLTGIWHLASEPISRFDLLTMLADRLGRRDV
KIVPSDGEARNRALSARRLWSETGYLPPGWPAMVDELATAIERRDIEGSSRRLPAPRPGGPEAPAPPSPPRTECTPMPDR
NLDEHGSGNRPPHQPWSAEPVDPLR

Sequences:

>Translated_345_residues
MRVLVLGGDGMLGGELVRRLVRDHDVTATVRATAPSCPPPADRVLSGVDVRRRDTMVDAFAAVRPDAVVNAVSLVGRRAE
GRAELSAIEVNALFPHRLARLCQAAGARLVHVSTDCVFSGRLGDYHEEDVPDPVDVHGMTKLLGEVTEPGTLTLRTSVVG
LEAVPAASGLVEGFLAAKGEIPASRRVVHSALTTAEFARFVHLVLVGHPDLTGIWHLASEPISRFDLLTMLADRLGRRDV
KIVPSDGEARNRALSARRLWSETGYLPPGWPAMVDELATAIERRDIEGSSRRLPAPRPGGPEAPAPPSPPRTECTPMPDR
NLDEHGSGNRPPHQPWSAEPVDPLR
>Mature_345_residues
MRVLVLGGDGMLGGELVRRLVRDHDVTATVRATAPSCPPPADRVLSGVDVRRRDTMVDAFAAVRPDAVVNAVSLVGRRAE
GRAELSAIEVNALFPHRLARLCQAAGARLVHVSTDCVFSGRLGDYHEEDVPDPVDVHGMTKLLGEVTEPGTLTLRTSVVG
LEAVPAASGLVEGFLAAKGEIPASRRVVHSALTTAEFARFVHLVLVGHPDLTGIWHLASEPISRFDLLTMLADRLGRRDV
KIVPSDGEARNRALSARRLWSETGYLPPGWPAMVDELATAIERRDIEGSSRRLPAPRPGGPEAPAPPSPPRTECTPMPDR
NLDEHGSGNRPPHQPWSAEPVDPLR

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG1091

COG function: function code M; dTDP-4-dehydrorhamnose reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.133

Molecular weight: Translated: 37150; Mature: 37150

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVLGGDGMLGGELVRRLVRDHDVTATVRATAPSCPPPADRVLSGVDVRRRDTMVDAF
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHH
AAVRPDAVVNAVSLVGRRAEGRAELSAIEVNALFPHRLARLCQAAGARLVHVSTDCVFSG
HHHCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCEEEEEECCEEEEC
RLGDYHEEDVPDPVDVHGMTKLLGEVTEPGTLTLRTSVVGLEAVPAASGLVEGFLAAKGE
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCHHCCHHHHHHHHHHHHCCC
IPASRRVVHSALTTAEFARFVHLVLVGHPDLTGIWHLASEPISRFDLLTMLADRLGRRDV
CCHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCE
KIVPSDGEARNRALSARRLWSETGYLPPGWPAMVDELATAIERRDIEGSSRRLPAPRPGG
EEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEAPAPPSPPRTECTPMPDRNLDEHGSGNRPPHQPWSAEPVDPLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLVLGGDGMLGGELVRRLVRDHDVTATVRATAPSCPPPADRVLSGVDVRRRDTMVDAF
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHH
AAVRPDAVVNAVSLVGRRAEGRAELSAIEVNALFPHRLARLCQAAGARLVHVSTDCVFSG
HHHCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCEEEEEECCEEEEC
RLGDYHEEDVPDPVDVHGMTKLLGEVTEPGTLTLRTSVVGLEAVPAASGLVEGFLAAKGE
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCHHCCHHHHHHHHHHHHCCC
IPASRRVVHSALTTAEFARFVHLVLVGHPDLTGIWHLASEPISRFDLLTMLADRLGRRDV
CCHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCE
KIVPSDGEARNRALSARRLWSETGYLPPGWPAMVDELATAIERRDIEGSSRRLPAPRPGG
EEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEAPAPPSPPRTECTPMPDRNLDEHGSGNRPPHQPWSAEPVDPLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-6-deoxy-L-mannose; NADP+

Specific reaction: dTDP-6-deoxy-L-mannose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA