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The map label for this gene is sat/cysC [H]

Identifier: 158316927

GI number: 158316927

Start: 6203249

End: 6205069

Strand: Direct

Name: sat/cysC [H]

Synonym: Franean1_5171

Alternate gene names: 158316927

Gene position: 6203249-6205069 (Clockwise)

Preceding gene: 158316924

Following gene: 158316932

Centisome position: 69.06

GC content: 77.43

Gene sequence:

>1821_bases
GTGAGCGCCACCTCCGACACCGCCGTCGGCTCGTTCGACCCGGATCCGCATGCCACGGCTGGTCCGCCCGACATACCGGG
CGCTGGTGAGCAGCGCGGCGCGAACGGCGTCTGTCCGCTTGCCGTCGTCGCTGCCGACCGCGCCCGCGAGCTGCGGGCCG
CCTCGGTGGCCTGGCCGTCGGTCGTGCTCGACACGCGCCAGCTCACCGACCTGGAGCTGATGCTGCTCGGCGCGTTCGGC
CCGGCGCCGAGCTACTCGGGCCGGGCCCGCCAGCCCGCCGGGCCGCCGGTGCCGAGCCTGACCGTCCCCGGTGAGACAGC
GGCCGCGCTGGGCCCGGGCATGGACGTCGCGCTGCGCGACCGCGAGGGCGTGATGATCGCGGCCCTGCACCTGCTCGGTC
TGGAGCCCACCGCGGACGACTCACCGACGCCCGCCACCGCGATGCCGGCGGAGGCCTCCGGAACGCCGGCGACTGCCACC
GGGGCGGGCCCGGTGCGCCTGGTCGGCACGGTGGAGGGCCTGGAGCTGCCCAGCCATCCGGACTACCCGCGGCTACGGCT
GACCCCGGAAGGGCTGCGCGCCGAGTTCGTCGCCCGGGGCTGGGCGACCGGCGCGGGCGCGGCCCCGTGGGCGGTGTGGG
CCGACGGCCTGCTGTACACCGCCGACGTCGGGCGCATCCGCGCGCTGACCCGGCAGGGCAAGCACTGCGTGATCCTGGCC
CCGGTCGGCGGGGCGGACCCGGCCGACGCCGCACACCACCTGCGGGTGCGCTGCCTGCTCGCCGCGCTGGACGCGATCGA
CGCACCGCCCCGGCCGGCCGAGGCGACGCTGGCCCACGAGCCGGTCGCCTCCGACGCGGTGTCGCGGGACGGCGGCCGGA
CGCATCCGGCCAGCCCGCCGGAGCCGGCCCACACCGCGGCGCTCGCGCCGGAGTCCCGCCGGCACCGCAGCATGCTCGTG
CTGGTCCCGGTCGTCCCGTCGGAGCGGCTCGCCGCGCCCCGTGAGCCGGCGATGAGCGCGACCGCCCCGGGCGGCCTGGC
CGACGAGGCGGCGAGTGAGCCGGCGTTGGACGAGATCGCCGAACTCACCGCCCTGCGGGCCCATCTCGCCGAGGTCTACG
GCTGTGCCGGCAGCCTGACCGGGCCGGCGATCGGCGCGCCGGGCGCCGACGATCTCACGACCCTGCTCGACGCGGGTGTG
CCGCTGCCCGCCGAGCTCACCCCGCCCGCGGTGGCTGCCGAGCTGACCCGCGCGGTTCCCCCGCGCCGCCAGCGCGGCCT
GACGATCCTGTTCACCGGGCTGTCCGGCTCGGGCAAGTCGACCCTGGCGGGTCTGTTGGTGTGCCGGCTGCTCGAACGGG
GCCGGCGGGTCACCCTGCTCGACGGCGACATCGTGCGGACGCATCTCTCCCAGGGCCTGGGCTTCTCCCGCGCCGACCGG
GACACGAACGTGCGCCGCATCGGCTTCGTCGCCGCGGAGGTCGCGGGCGCCGGCGGGATCGCCGTGTGCGCGCCGATCGC
GCCCTACGACGACGTCCGCGCCCAGGTGCGGGCGATGACCACCGCCCGCGGCGGCGGCTTCGTGCTCGTGTACGTGTCGA
CCCCGCTGGAGGTGTGCGAGGCACGGGACCGCAAGGGCCTCTACGCCAAGGCCCGGGCGGGGGTGATCCCCGCCTTCACC
GGCGTCTCCGACCCGTACGAGGAGCCGGCCGACGCCGACGTGGTGGTCGACACGGCGGGCCTGCCGACCGAGCAGGCCGT
CGACCGGGTGCTCGCGCACCTGGTCGAGGCCGGCTGGGTCGAGGGCGCCCGCGGCCAGTAG

Upstream 100 bases:

>100_bases
TCCGTGGCGATGTCGACCGGAACCGTGGCGAACCCGTCCGGCCGGCGGATGTCGTCGGTGCTCATCGGGTGGGAGTCTTC
CACCCGCTACCGTCGCGGGT

Downstream 100 bases:

>100_bases
GCCCCAGCGGGCACCCGCCAGCCCGCTGGCAGCAGGAGGGACCCGCTGTCAGTAGGCGCCCTCGCGGCGCAGCACGGCGA
ACAGCGTGCGCCACAGGATG

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: Sulfate adenylyltransferase; ATP-sulfurylase; Sulfate adenylate transferase; SAT; Adenylyl-sulfate kinase; APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MSATSDTAVGSFDPDPHATAGPPDIPGAGEQRGANGVCPLAVVAADRARELRAASVAWPSVVLDTRQLTDLELMLLGAFG
PAPSYSGRARQPAGPPVPSLTVPGETAAALGPGMDVALRDREGVMIAALHLLGLEPTADDSPTPATAMPAEASGTPATAT
GAGPVRLVGTVEGLELPSHPDYPRLRLTPEGLRAEFVARGWATGAGAAPWAVWADGLLYTADVGRIRALTRQGKHCVILA
PVGGADPADAAHHLRVRCLLAALDAIDAPPRPAEATLAHEPVASDAVSRDGGRTHPASPPEPAHTAALAPESRRHRSMLV
LVPVVPSERLAAPREPAMSATAPGGLADEAASEPALDEIAELTALRAHLAEVYGCAGSLTGPAIGAPGADDLTTLLDAGV
PLPAELTPPAVAAELTRAVPPRRQRGLTILFTGLSGSGKSTLAGLLVCRLLERGRRVTLLDGDIVRTHLSQGLGFSRADR
DTNVRRIGFVAAEVAGAGGIAVCAPIAPYDDVRAQVRAMTTARGGGFVLVYVSTPLEVCEARDRKGLYAKARAGVIPAFT
GVSDPYEEPADADVVVDTAGLPTEQAVDRVLAHLVEAGWVEGARGQ

Sequences:

>Translated_606_residues
MSATSDTAVGSFDPDPHATAGPPDIPGAGEQRGANGVCPLAVVAADRARELRAASVAWPSVVLDTRQLTDLELMLLGAFG
PAPSYSGRARQPAGPPVPSLTVPGETAAALGPGMDVALRDREGVMIAALHLLGLEPTADDSPTPATAMPAEASGTPATAT
GAGPVRLVGTVEGLELPSHPDYPRLRLTPEGLRAEFVARGWATGAGAAPWAVWADGLLYTADVGRIRALTRQGKHCVILA
PVGGADPADAAHHLRVRCLLAALDAIDAPPRPAEATLAHEPVASDAVSRDGGRTHPASPPEPAHTAALAPESRRHRSMLV
LVPVVPSERLAAPREPAMSATAPGGLADEAASEPALDEIAELTALRAHLAEVYGCAGSLTGPAIGAPGADDLTTLLDAGV
PLPAELTPPAVAAELTRAVPPRRQRGLTILFTGLSGSGKSTLAGLLVCRLLERGRRVTLLDGDIVRTHLSQGLGFSRADR
DTNVRRIGFVAAEVAGAGGIAVCAPIAPYDDVRAQVRAMTTARGGGFVLVYVSTPLEVCEARDRKGLYAKARAGVIPAFT
GVSDPYEEPADADVVVDTAGLPTEQAVDRVLAHLVEAGWVEGARGQ
>Mature_605_residues
SATSDTAVGSFDPDPHATAGPPDIPGAGEQRGANGVCPLAVVAADRARELRAASVAWPSVVLDTRQLTDLELMLLGAFGP
APSYSGRARQPAGPPVPSLTVPGETAAALGPGMDVALRDREGVMIAALHLLGLEPTADDSPTPATAMPAEASGTPATATG
AGPVRLVGTVEGLELPSHPDYPRLRLTPEGLRAEFVARGWATGAGAAPWAVWADGLLYTADVGRIRALTRQGKHCVILAP
VGGADPADAAHHLRVRCLLAALDAIDAPPRPAEATLAHEPVASDAVSRDGGRTHPASPPEPAHTAALAPESRRHRSMLVL
VPVVPSERLAAPREPAMSATAPGGLADEAASEPALDEIAELTALRAHLAEVYGCAGSLTGPAIGAPGADDLTTLLDAGVP
LPAELTPPAVAAELTRAVPPRRQRGLTILFTGLSGSGKSTLAGLLVCRLLERGRRVTLLDGDIVRTHLSQGLGFSRADRD
TNVRRIGFVAAEVAGAGGIAVCAPIAPYDDVRAQVRAMTTARGGGFVLVYVSTPLEVCEARDRKGLYAKARAGVIPAFTG
VSDPYEEPADADVVVDTAGLPTEQAVDRVLAHLVEAGWVEGARGQ

Specific function: Catalyzes The Synthesis Of Activated Sulfate. [C]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=172, Percent_Identity=42.4418604651163, Blast_Score=130, Evalue=5e-30,
Organism=Homo sapiens, GI62912492, Length=176, Percent_Identity=39.7727272727273, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI34447231, Length=176, Percent_Identity=39.7727272727273, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1789107, Length=173, Percent_Identity=46.242774566474, Blast_Score=133, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17542422, Length=174, Percent_Identity=44.2528735632184, Blast_Score=145, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6322852, Length=174, Percent_Identity=41.9540229885057, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24667032, Length=176, Percent_Identity=42.6136363636364, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24667028, Length=176, Percent_Identity=42.6136363636364, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24667036, Length=176, Percent_Identity=42.6136363636364, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI116007838, Length=176, Percent_Identity=42.6136363636364, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24667044, Length=176, Percent_Identity=42.6136363636364, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24667040, Length=176, Percent_Identity=42.6136363636364, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891
- InterPro:   IPR015947
- InterPro:   IPR014729
- InterPro:   IPR020792
- InterPro:   IPR002650 [H]

Pfam domain/function: PF01583 APS_kinase; PF01747 ATP-sulfurylase [H]

EC number: =2.7.7.4; =2.7.1.25 [H]

Molecular weight: Translated: 62092; Mature: 61961

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATSDTAVGSFDPDPHATAGPPDIPGAGEQRGANGVCPLAVVAADRARELRAASVAWPS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCH
VVLDTRQLTDLELMLLGAFGPAPSYSGRARQPAGPPVPSLTVPGETAAALGPGMDVALRD
HEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHCCCCCCEEEEC
REGVMIAALHLLGLEPTADDSPTPATAMPAEASGTPATATGAGPVRLVGTVEGLELPSHP
CCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
DYPRLRLTPEGLRAEFVARGWATGAGAAPWAVWADGLLYTADVGRIRALTRQGKHCVILA
CCCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHCCEEEECCHHHHHHHHHCCCEEEEEE
PVGGADPADAAHHLRVRCLLAALDAIDAPPRPAEATLAHEPVASDAVSRDGGRTHPASPP
ECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHCCCCCCCCCCCC
EPAHTAALAPESRRHRSMLVLVPVVPSERLAAPREPAMSATAPGGLADEAASEPALDEIA
CCCCHHHCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCCCCCCCCHHHCCCCHHHHHH
ELTALRAHLAEVYGCAGSLTGPAIGAPGADDLTTLLDAGVPLPAELTPPAVAAELTRAVP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
PRRQRGLTILFTGLSGSGKSTLAGLLVCRLLERGRRVTLLDGDIVRTHLSQGLGFSRADR
CHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCC
DTNVRRIGFVAAEVAGAGGIAVCAPIAPYDDVRAQVRAMTTARGGGFVLVYVSTPLEVCE
CCCCEEEEEEEHHHCCCCCEEEEECCCCHHHHHHHHHHHHEECCCCEEEEEECCCHHHHH
ARDRKGLYAKARAGVIPAFTGVSDPYEEPADADVVVDTAGLPTEQAVDRVLAHLVEAGWV
HHCCCCCEEHHHCCCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCC
EGARGQ
CCCCCC
>Mature Secondary Structure 
SATSDTAVGSFDPDPHATAGPPDIPGAGEQRGANGVCPLAVVAADRARELRAASVAWPS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCH
VVLDTRQLTDLELMLLGAFGPAPSYSGRARQPAGPPVPSLTVPGETAAALGPGMDVALRD
HEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHCCCCCCEEEEC
REGVMIAALHLLGLEPTADDSPTPATAMPAEASGTPATATGAGPVRLVGTVEGLELPSHP
CCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
DYPRLRLTPEGLRAEFVARGWATGAGAAPWAVWADGLLYTADVGRIRALTRQGKHCVILA
CCCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHCCEEEECCHHHHHHHHHCCCEEEEEE
PVGGADPADAAHHLRVRCLLAALDAIDAPPRPAEATLAHEPVASDAVSRDGGRTHPASPP
ECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHCCCCCCCCCCCC
EPAHTAALAPESRRHRSMLVLVPVVPSERLAAPREPAMSATAPGGLADEAASEPALDEIA
CCCCHHHCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCCCCCCCCHHHCCCCHHHHHH
ELTALRAHLAEVYGCAGSLTGPAIGAPGADDLTTLLDAGVPLPAELTPPAVAAELTRAVP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
PRRQRGLTILFTGLSGSGKSTLAGLLVCRLLERGRRVTLLDGDIVRTHLSQGLGFSRADR
CHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCC
DTNVRRIGFVAAEVAGAGGIAVCAPIAPYDDVRAQVRAMTTARGGGFVLVYVSTPLEVCE
CCCCEEEEEEEHHHCCCCCEEEEECCCCHHHHHHHHHHHHEECCCCEEEEEECCCHHHHH
ARDRKGLYAKARAGVIPAFTGVSDPYEEPADADVVVDTAGLPTEQAVDRVLAHLVEAGWV
HHCCCCCEEHHHCCCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCC
EGARGQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]