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The map label for this gene is murC [H]

Identifier: 158316854

GI number: 158316854

Start: 6100453

End: 6101952

Strand: Reverse

Name: murC [H]

Synonym: Franean1_5097

Alternate gene names: 158316854

Gene position: 6101952-6100453 (Counterclockwise)

Preceding gene: 158316855

Following gene: 158316851

Centisome position: 67.94

GC content: 78.47

Gene sequence:

>1500_bases
GTGACGGCGCGAGATCTCCCGGAGGGCTGGCGGCGGGTCCACCTCGTCGGCATCGGCGGGATCGCCATGAGCGGTCTGGC
ACGGTTGCTGGTCGCGCGGGGCGCGACGGTCTCCGGCAGCGACGCGGTCGAGTCCCGGCGGCTGGCGTCGCTGCGCGCGC
TCGGCGTCCCGGTCACGGTGGGCAACGGCCCCGACAGGTTCGACGCCTCGCGCCTCGACGGGGTCGAGCTGGTCGTCGTC
GCGCCAGCGGTGCCGGGCGACGACCTGGAGCTCGCCGAGGCGCGCCGGCGCGAGCTGCGGGTGCTGACCCGCTCCGCCGC
GCTCGCCGGGCTGATGGCCGGGCACCGAGGCGTGGCGGTCGCGGGCTCGCACGGCAAGACCACCGTGGCGATGATGCTCA
CCGCCGCCCTGCAGGCCTGCGGCGCGGACCCGACGTTCGCGGTCGGCGGGGATCCGGGCGAGGCCGGCTCGCACACCCAC
GCGGGCAGCTCCGAGCTGATGGTCGTCGAGGCGGACGAGGACGCCGGCGCGTTCTGGCAGCTCCAGCCGTACGGCGCGGT
GCTGACAGGGGTGGCCGCCGAGCACCTCGACCACTACCGGACGATGCCCGCCCTCGCCGCCTCGTTCGCGACGTTCCTGC
GCCGGGTCGACCCGGGCGGCTTCCTGGTCGCCTGCGTGGACGACGCGGCCGGGTGGGCGCTCGCCACGGCGGCGGCCGAC
CACGCCGACCGCTGGCGCCGGGCCGGCGCCAGCGCCAGCGCCAGCGCCCCGGACGGTGGCCGGCCGTGGCTGACGGGGTA
CGGGTTCGGGCCGTCGGCGGACGTCCGGCTCGTCGCCGAGGAGATCTCGATCGCGGGCACCAGCGCGGAGGTCGTCGTCC
ATGGCGTCCGGCTGGGCCGGCTGTCGCTGCGGGTCCCCGGCCGGCACCACCTCCTGGACGCCGCGGCGGCCCTGGCCGCC
GGGATCGCCCTGGGCGCCCCGCCGGCCGGCCTGCTGGCCGGGCTGACCGAGTTCGCCGGGGTCCGCCGCCGCTTCGAGTC
GCTCGGGTCGGCGGGCGGGGTGCGGGTGGTCGACGACTACGCCAACCACCCGGACCGGGTGGCCGCCGCGGTCGAGGCGG
CGCGGGCGGCTGCCGGCGGCGGCCGGGTCGTCGTCGCGTTCCAGCCGCACCTGTACAGCCGCACGGCCCTGCTCGCCGAC
CGGTTCGGTGCCGCGCTGGGCTCGGCCGACGCGGTCGTGGTGATGGACGTCTACGGCGCCGGGGAGCAGCCCGAACCGGG
CGCGGGCGGTGCCCGGGTCGCCGCGGCCACCCGGTCCGGGGCGGCGCGGGTCGGGGCGGCGCGGGTCGTGTACGAGCCGT
CGTGGTCGGCCGTCCCGGGCGTGCTGATGGACCTGGCACGGCCGGGCGACCTGGTCATGACGCTCGGCGCCGGGGACGTG
ACGCAGGTCGGCCCGGAGCTGCTGCGTCTGCTGGCCGAACGGTCGGCCCTGCCGGGCTAG

Upstream 100 bases:

>100_bases
GGCACGCGGCGAACTGAGTGGCCGTGGTCAGCCTTCCCGCGCCCGCGCGGCGCCGGAGTCCGCTGCGTGCCTGCGCGCGG
CGCTGCGGCAGGATGGCGAC

Downstream 100 bases:

>100_bases
CCCGAGCGGCGGACCCTAGCGCACGACCGAGCCGCAAGCCCGAGGCCGAATCGCAGGCCCAAGCCTCGCCAGGCCCCAGT
TTGATGATCCATCGCAGAGG

Product: UDP-N-acetylmuramate--alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTARDLPEGWRRVHLVGIGGIAMSGLARLLVARGATVSGSDAVESRRLASLRALGVPVTVGNGPDRFDASRLDGVELVVV
APAVPGDDLELAEARRRELRVLTRSAALAGLMAGHRGVAVAGSHGKTTVAMMLTAALQACGADPTFAVGGDPGEAGSHTH
AGSSELMVVEADEDAGAFWQLQPYGAVLTGVAAEHLDHYRTMPALAASFATFLRRVDPGGFLVACVDDAAGWALATAAAD
HADRWRRAGASASASAPDGGRPWLTGYGFGPSADVRLVAEEISIAGTSAEVVVHGVRLGRLSLRVPGRHHLLDAAAALAA
GIALGAPPAGLLAGLTEFAGVRRRFESLGSAGGVRVVDDYANHPDRVAAAVEAARAAAGGGRVVVAFQPHLYSRTALLAD
RFGAALGSADAVVVMDVYGAGEQPEPGAGGARVAAATRSGAARVGAARVVYEPSWSAVPGVLMDLARPGDLVMTLGAGDV
TQVGPELLRLLAERSALPG

Sequences:

>Translated_499_residues
MTARDLPEGWRRVHLVGIGGIAMSGLARLLVARGATVSGSDAVESRRLASLRALGVPVTVGNGPDRFDASRLDGVELVVV
APAVPGDDLELAEARRRELRVLTRSAALAGLMAGHRGVAVAGSHGKTTVAMMLTAALQACGADPTFAVGGDPGEAGSHTH
AGSSELMVVEADEDAGAFWQLQPYGAVLTGVAAEHLDHYRTMPALAASFATFLRRVDPGGFLVACVDDAAGWALATAAAD
HADRWRRAGASASASAPDGGRPWLTGYGFGPSADVRLVAEEISIAGTSAEVVVHGVRLGRLSLRVPGRHHLLDAAAALAA
GIALGAPPAGLLAGLTEFAGVRRRFESLGSAGGVRVVDDYANHPDRVAAAVEAARAAAGGGRVVVAFQPHLYSRTALLAD
RFGAALGSADAVVVMDVYGAGEQPEPGAGGARVAAATRSGAARVGAARVVYEPSWSAVPGVLMDLARPGDLVMTLGAGDV
TQVGPELLRLLAERSALPG
>Mature_498_residues
TARDLPEGWRRVHLVGIGGIAMSGLARLLVARGATVSGSDAVESRRLASLRALGVPVTVGNGPDRFDASRLDGVELVVVA
PAVPGDDLELAEARRRELRVLTRSAALAGLMAGHRGVAVAGSHGKTTVAMMLTAALQACGADPTFAVGGDPGEAGSHTHA
GSSELMVVEADEDAGAFWQLQPYGAVLTGVAAEHLDHYRTMPALAASFATFLRRVDPGGFLVACVDDAAGWALATAAADH
ADRWRRAGASASASAPDGGRPWLTGYGFGPSADVRLVAEEISIAGTSAEVVVHGVRLGRLSLRVPGRHHLLDAAAALAAG
IALGAPPAGLLAGLTEFAGVRRRFESLGSAGGVRVVDDYANHPDRVAAAVEAARAAAGGGRVVVAFQPHLYSRTALLADR
FGAALGSADAVVVMDVYGAGEQPEPGAGGARVAAATRSGAARVGAARVVYEPSWSAVPGVLMDLARPGDLVMTLGAGDVT
QVGPELLRLLAERSALPG

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=500, Percent_Identity=33, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1790680, Length=500, Percent_Identity=26.6, Blast_Score=145, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 50652; Mature: 50521

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARDLPEGWRRVHLVGIGGIAMSGLARLLVARGATVSGSDAVESRRLASLRALGVPVTV
CCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEE
GNGPDRFDASRLDGVELVVVAPAVPGDDLELAEARRRELRVLTRSAALAGLMAGHRGVAV
CCCCCCCCHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AGSHGKTTVAMMLTAALQACGADPTFAVGGDPGEAGSHTHAGSSELMVVEADEDAGAFWQ
ECCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCEEE
LQPYGAVLTGVAAEHLDHYRTMPALAASFATFLRRVDPGGFLVACVDDAAGWALATAAAD
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHH
HADRWRRAGASASASAPDGGRPWLTGYGFGPSADVRLVAEEISIAGTSAEVVVHGVRLGR
HHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEHHHCCCCCCEEEEEEEEEEE
LSLRVPGRHHLLDAAAALAAGIALGAPPAGLLAGLTEFAGVRRRFESLGSAGGVRVVDDY
EEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
ANHPDRVAAAVEAARAAAGGGRVVVAFQPHLYSRTALLADRFGAALGSADAVVVMDVYGA
CCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
GEQPEPGAGGARVAAATRSGAARVGAARVVYEPSWSAVPGVLMDLARPGDLVMTLGAGDV
CCCCCCCCCCCEEEEECCCCCHHCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCH
TQVGPELLRLLAERSALPG
HHHCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TARDLPEGWRRVHLVGIGGIAMSGLARLLVARGATVSGSDAVESRRLASLRALGVPVTV
CCCCCCCCCEEEEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEE
GNGPDRFDASRLDGVELVVVAPAVPGDDLELAEARRRELRVLTRSAALAGLMAGHRGVAV
CCCCCCCCHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AGSHGKTTVAMMLTAALQACGADPTFAVGGDPGEAGSHTHAGSSELMVVEADEDAGAFWQ
ECCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCEEE
LQPYGAVLTGVAAEHLDHYRTMPALAASFATFLRRVDPGGFLVACVDDAAGWALATAAAD
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHH
HADRWRRAGASASASAPDGGRPWLTGYGFGPSADVRLVAEEISIAGTSAEVVVHGVRLGR
HHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEHHHCCCCCCEEEEEEEEEEE
LSLRVPGRHHLLDAAAALAAGIALGAPPAGLLAGLTEFAGVRRRFESLGSAGGVRVVDDY
EEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
ANHPDRVAAAVEAARAAAGGGRVVVAFQPHLYSRTALLADRFGAALGSADAVVVMDVYGA
CCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
GEQPEPGAGGARVAAATRSGAARVGAARVVYEPSWSAVPGVLMDLARPGDLVMTLGAGDV
CCCCCCCCCCCEEEEECCCCCHHCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCH
TQVGPELLRLLAERSALPG
HHHCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA