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The map label for this gene is yccK [H]

Identifier: 158316725

GI number: 158316725

Start: 5955548

End: 5956534

Strand: Reverse

Name: yccK [H]

Synonym: Franean1_4963

Alternate gene names: 158316725

Gene position: 5956534-5955548 (Counterclockwise)

Preceding gene: 158316727

Following gene: 158316722

Centisome position: 66.32

GC content: 72.44

Gene sequence:

>987_bases
ATGACCGACGTCCCCACCCGGCACCTAGGCGAACTGGCGGTTTCCGCGCAGGGCCTGGGGTGCATGGGCATGAGCCACGG
CTACGGCGCCGCGGACGACGCGCAGTCGATCGCGACGCTGCACCACGCCCTCGCCCTCGGGGTGACCTTCCTGGACACCT
CCGACTTCTACGGCGACGGGCACAACGAGGAGCTGATCGGACGGGCCATCGCCGGGCGCCGCGACGAGGTGGTGCTGGCC
ACGAAGTTCGGCTTCGCCAACCGCTTGGGCGAGCCCACCCGGATCCGCGGCGACGCCGCCTACGTGCGGCAGGCGTGCGA
GGCGTCGCTGCGCCGGCTCGGGGTCGACCATATCGACCTCTACTACCAGCACCGGGTCGATCCGCAGGTGCCGATCGAGG
AGACCGTCGGCGCCATGGCCGAGCTGGTGCGGGCCGGGAAGGTCCGCCACCTCGGGCTGTCCGAGGCCGGCGTGCGAACC
ATCCGGCGGGCGCACGCGGTGCACCCGATCGCCGCGCTGCAGAGCGAGTGGTCGCTGTGGACCCGCGACCTGGAGGCGGA
GATCGTGCCGGTCTGCCGCGATCTTGGTATCGGCCTGGTCCCGTTCTCCCCGCTGGGGCGCGGCTTCCTGACCGGTCGGT
ACAGCTCGGTCGAGGGGCTGGCGGAGACCGACGTGCGGCGCGGCCAGCCGCGTTTCGCCGACGGCAACCTCGAACGGAAC
CTGGCGATCGTCGCGAAGCTGAACGAGCTGGCTGCGGCGAAGGGAGTCACCGCCGGCCAGCTCGCCCTGGCCTGGGTGCA
GCACCGGGGCGACGACGTGGTGCCGATCCCCGGCACTCGGCGGCAGCGGTACCTGGAGGAGAACCTCGCGGCCCTGGCCG
TCGAGCTGTCCACCGAGGACCTCGCCGCCATCGAGGCCGCCGCTCCGCCCGAGCAGGTCGCGGGCACCCGCTACGACGCG
ACCAGCCTCACCTTCGTCAACGGCTGA

Upstream 100 bases:

>100_bases
GCTACCAGGGCCGGTGATGGCGTTCACGCCCGGTTGACATCGAGCGCGCTCCAACACCTAGCGTCGTGGGCAGACGGTTC
CGAGCCCAGGAGACAGCAGC

Downstream 100 bases:

>100_bases
GCCCGCCGCGGGGCTTCGTCCCCGGACCGGTTCCGGCGGCTCCCGCCCAGTGAGCTGGTCCTGAGTGGTCGTTATTGAGC
TGTTGCAGTTCTTCCTGCCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTDVPTRHLGELAVSAQGLGCMGMSHGYGAADDAQSIATLHHALALGVTFLDTSDFYGDGHNEELIGRAIAGRRDEVVLA
TKFGFANRLGEPTRIRGDAAYVRQACEASLRRLGVDHIDLYYQHRVDPQVPIEETVGAMAELVRAGKVRHLGLSEAGVRT
IRRAHAVHPIAALQSEWSLWTRDLEAEIVPVCRDLGIGLVPFSPLGRGFLTGRYSSVEGLAETDVRRGQPRFADGNLERN
LAIVAKLNELAAAKGVTAGQLALAWVQHRGDDVVPIPGTRRQRYLEENLAALAVELSTEDLAAIEAAAPPEQVAGTRYDA
TSLTFVNG

Sequences:

>Translated_328_residues
MTDVPTRHLGELAVSAQGLGCMGMSHGYGAADDAQSIATLHHALALGVTFLDTSDFYGDGHNEELIGRAIAGRRDEVVLA
TKFGFANRLGEPTRIRGDAAYVRQACEASLRRLGVDHIDLYYQHRVDPQVPIEETVGAMAELVRAGKVRHLGLSEAGVRT
IRRAHAVHPIAALQSEWSLWTRDLEAEIVPVCRDLGIGLVPFSPLGRGFLTGRYSSVEGLAETDVRRGQPRFADGNLERN
LAIVAKLNELAAAKGVTAGQLALAWVQHRGDDVVPIPGTRRQRYLEENLAALAVELSTEDLAAIEAAAPPEQVAGTRYDA
TSLTFVNG
>Mature_327_residues
TDVPTRHLGELAVSAQGLGCMGMSHGYGAADDAQSIATLHHALALGVTFLDTSDFYGDGHNEELIGRAIAGRRDEVVLAT
KFGFANRLGEPTRIRGDAAYVRQACEASLRRLGVDHIDLYYQHRVDPQVPIEETVGAMAELVRAGKVRHLGLSEAGVRTI
RRAHAVHPIAALQSEWSLWTRDLEAEIVPVCRDLGIGLVPFSPLGRGFLTGRYSSVEGLAETDVRRGQPRFADGNLERNL
AIVAKLNELAAAKGVTAGQLALAWVQHRGDDVVPIPGTRRQRYLEENLAALAVELSTEDLAAIEAAAPPEQVAGTRYDAT
SLTFVNG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=319, Percent_Identity=27.8996865203762, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4504825, Length=319, Percent_Identity=27.8996865203762, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI27436966, Length=312, Percent_Identity=27.5641025641026, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=27.2435897435897, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI27436962, Length=312, Percent_Identity=27.2435897435897, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI27436971, Length=318, Percent_Identity=27.3584905660377, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI223718702, Length=289, Percent_Identity=30.7958477508651, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI41327764, Length=276, Percent_Identity=31.5217391304348, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI41152114, Length=304, Percent_Identity=29.9342105263158, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081735, Length=322, Percent_Identity=32.6086956521739, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789375, Length=307, Percent_Identity=30.9446254071661, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788070, Length=308, Percent_Identity=30.8441558441558, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788081, Length=304, Percent_Identity=31.25, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787674, Length=311, Percent_Identity=31.1897106109325, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789199, Length=332, Percent_Identity=29.5180722891566, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI48994888, Length=126, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=28.1437125748503, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323998, Length=307, Percent_Identity=28.3387622149837, Blast_Score=119, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6319958, Length=302, Percent_Identity=28.1456953642384, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325384, Length=332, Percent_Identity=28.0120481927711, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322615, Length=254, Percent_Identity=28.3464566929134, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=287, Percent_Identity=28.2229965156794, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24657054, Length=329, Percent_Identity=24.9240121580547, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646155, Length=163, Percent_Identity=30.6748466257669, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24646159, Length=164, Percent_Identity=31.0975609756098, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35326; Mature: 35195

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVPTRHLGELAVSAQGLGCMGMSHGYGAADDAQSIATLHHALALGVTFLDTSDFYGDG
CCCCCCHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCC
HNEELIGRAIAGRRDEVVLATKFGFANRLGEPTRIRGDAAYVRQACEASLRRLGVDHIDL
CCHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCHHHHH
YYQHRVDPQVPIEETVGAMAELVRAGKVRHLGLSEAGVRTIRRAHAVHPIAALQSEWSLW
HHHHCCCCCCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TRDLEAEIVPVCRDLGIGLVPFSPLGRGFLTGRYSSVEGLAETDVRRGQPRFADGNLERN
HHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
LAIVAKLNELAAAKGVTAGQLALAWVQHRGDDVVPIPGTRRQRYLEENLAALAVELSTED
EEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHEEEEECCHH
LAAIEAAAPPEQVAGTRYDATSLTFVNG
HHHHHCCCCHHHHCCCCCCCCEEEEECC
>Mature Secondary Structure 
TDVPTRHLGELAVSAQGLGCMGMSHGYGAADDAQSIATLHHALALGVTFLDTSDFYGDG
CCCCCHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCC
HNEELIGRAIAGRRDEVVLATKFGFANRLGEPTRIRGDAAYVRQACEASLRRLGVDHIDL
CCHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCHHHHH
YYQHRVDPQVPIEETVGAMAELVRAGKVRHLGLSEAGVRTIRRAHAVHPIAALQSEWSLW
HHHHCCCCCCCHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TRDLEAEIVPVCRDLGIGLVPFSPLGRGFLTGRYSSVEGLAETDVRRGQPRFADGNLERN
HHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
LAIVAKLNELAAAKGVTAGQLALAWVQHRGDDVVPIPGTRRQRYLEENLAALAVELSTED
EEEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHEEEEECCHH
LAAIEAAAPPEQVAGTRYDATSLTFVNG
HHHHHCCCCHHHHCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]