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The map label for this gene is sufS [H]

Identifier: 158316685

GI number: 158316685

Start: 5908905

End: 5910461

Strand: Reverse

Name: sufS [H]

Synonym: Franean1_4922

Alternate gene names: 158316685

Gene position: 5910461-5908905 (Counterclockwise)

Preceding gene: 158316686

Following gene: 158316684

Centisome position: 65.8

GC content: 76.81

Gene sequence:

>1557_bases
GTGTCCCTTTCGTATGCCACCACGTCTCCCGACGTTGATCGGGAAGGGCCCGCCGTCGGCGCGCTGCTCGACGTGGTGGG
GGCCGGCATCCCCGTTCCGCTCGCCGACGGACGCGAGGTCCCGTACGCCAATCTCGACCAGGCCGCCAGCGCCCCCTGCC
TGCGCGGGGTCGCCGAGCACGTCGAGCGCGTCCTGCCGTACTCGGCGAGCGTGCACCGCGGAACCGGCTACTCCTCCGCG
GTCTGCACCGCGCTCTACGAGGGGGCCCGCGCCGCCGTGCGCACGTTCGTCGGCGGCCGCCCGGACGACGTCGTGATCTT
CACCCGGAACACCACCGACTCGGTGAACCTGCTCGCCCGCTGCCTCCCGCCGCAGCCGCCCGACCCGCCGCAGCCGCCCG
ACCCGGCGCGGACGTCCGACCCGGGCCACGCCGAGCCCGGCGGGGTTGTCGTGTTCGACCTGGAGCATCACGCGAACCTT
CTCCCGTGGCGGTCCCGGCCGGGCTGCCGGTGGGTGCCCGCCGCGCCCACCCGCGCCGACACGCTGCGCGCGCTCGCCAC
CGCCCTGGACACGGCACCGACCTCGCTCGTCGCGGTGACCGGCGCGTCCAACGTCACCGGCGAGGTGCCGCCGCTCGCCG
AGATCGTCCGGCTGGCGCGCGCGGCCGGCGCGCGGGTCTTCGTGGACGGCGCCCAGCTCGTCCCGCACCGTCGGGTCGAC
ATGGCCGCGCTCGGCATCGACTACCTCGCGTTCTCCGGGCACAAGCTGTACGCGCCGTTCGGCGCCGGCGTGCTCGTCGG
ACGTCCGGACTGGCTGGCGGCGGCCCCGCCCTATCTCGCCGGCGGGGGCGCCGTGCGTGAGGTGACCAACTCCGCCGTGG
CCTGGGCGGACGGCCCGGCCCGGCACGAGGCCGGCAGCCCCAACCTCCTCGGCGCGACGGCGATCGCGGCCGCCTGCCGG
CTGCTGGGCGCGCTCGCCCCCCGCGACCTGCACCAGCACGAGGACCTGCTGCGCCGCCGCCTGGTGGACGGGCTGCGCGC
GATCGAGGGAGTCACCATCCACTCCCTGTGGGCCGACGGAGACGATCCCGCCGCTGGCGAGGCCGCCGGAGGCGAGGGCC
CGGACGGGATCCTGGCCACGGGGCCCGTCGGGGTCGTCACCTTCTCGGTCGCCGGGCGCGATCCCGGGTTCGTCGCCGCC
GTCCTCTCCGCCGAGCACGGCGTCGGGGTACGCGCCGGACGCTTCTGCGCGCATCCGCTGCTGGGGCGGCTCGGAGCCGA
GGGCGGCGCGATCCGCGCGAGTGTCGGCATCAGCTCGACGAGTGCCGACGTCGACAGGCTGCTGGCAGGGCTGGCGGAGC
TCGTCGGCCGCGGGCCGCGCCAGCAGTACCGCGACCTGGGCGACGGAGGCTGGGCTCCGGCATCGGACGGTCGCGCGCTG
CCGCCCTGGGTCGCCGAGCACATGGCGGCCGGTCACGTCCGCGGTCGTGTGCCCGCGCCGGGCCACGCGCACGACAGCGC
CGGCCTGCCCGCGTACTCCAGCCCCTGCGGGACCTGA

Upstream 100 bases:

>100_bases
CCGCGGTGGGGTGCCCCGGGTGTGACCAGGCCCGCGGCGAACCCGCCGTCGGCAAGTGCGGACCCCCTCTGGGTCCACCG
GGGCCCAAGGAGGCTTCGTC

Downstream 100 bases:

>100_bases
GCCGGCACGGGCGCGGATGTTCTCGTCATGGTGCGGACTCGCGGATGTCCGTCGTCCGGGCCCGGTTGCCCGCGTACGCT
TCGCACGGGGCACTGTCGCG

Product: cysteine desulfurase

Products: NA

Alternate protein names: Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase [H]

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSLSYATTSPDVDREGPAVGALLDVVGAGIPVPLADGREVPYANLDQAASAPCLRGVAEHVERVLPYSASVHRGTGYSSA
VCTALYEGARAAVRTFVGGRPDDVVIFTRNTTDSVNLLARCLPPQPPDPPQPPDPARTSDPGHAEPGGVVVFDLEHHANL
LPWRSRPGCRWVPAAPTRADTLRALATALDTAPTSLVAVTGASNVTGEVPPLAEIVRLARAAGARVFVDGAQLVPHRRVD
MAALGIDYLAFSGHKLYAPFGAGVLVGRPDWLAAAPPYLAGGGAVREVTNSAVAWADGPARHEAGSPNLLGATAIAAACR
LLGALAPRDLHQHEDLLRRRLVDGLRAIEGVTIHSLWADGDDPAAGEAAGGEGPDGILATGPVGVVTFSVAGRDPGFVAA
VLSAEHGVGVRAGRFCAHPLLGRLGAEGGAIRASVGISSTSADVDRLLAGLAELVGRGPRQQYRDLGDGGWAPASDGRAL
PPWVAEHMAAGHVRGRVPAPGHAHDSAGLPAYSSPCGT

Sequences:

>Translated_518_residues
MSLSYATTSPDVDREGPAVGALLDVVGAGIPVPLADGREVPYANLDQAASAPCLRGVAEHVERVLPYSASVHRGTGYSSA
VCTALYEGARAAVRTFVGGRPDDVVIFTRNTTDSVNLLARCLPPQPPDPPQPPDPARTSDPGHAEPGGVVVFDLEHHANL
LPWRSRPGCRWVPAAPTRADTLRALATALDTAPTSLVAVTGASNVTGEVPPLAEIVRLARAAGARVFVDGAQLVPHRRVD
MAALGIDYLAFSGHKLYAPFGAGVLVGRPDWLAAAPPYLAGGGAVREVTNSAVAWADGPARHEAGSPNLLGATAIAAACR
LLGALAPRDLHQHEDLLRRRLVDGLRAIEGVTIHSLWADGDDPAAGEAAGGEGPDGILATGPVGVVTFSVAGRDPGFVAA
VLSAEHGVGVRAGRFCAHPLLGRLGAEGGAIRASVGISSTSADVDRLLAGLAELVGRGPRQQYRDLGDGGWAPASDGRAL
PPWVAEHMAAGHVRGRVPAPGHAHDSAGLPAYSSPCGT
>Mature_517_residues
SLSYATTSPDVDREGPAVGALLDVVGAGIPVPLADGREVPYANLDQAASAPCLRGVAEHVERVLPYSASVHRGTGYSSAV
CTALYEGARAAVRTFVGGRPDDVVIFTRNTTDSVNLLARCLPPQPPDPPQPPDPARTSDPGHAEPGGVVVFDLEHHANLL
PWRSRPGCRWVPAAPTRADTLRALATALDTAPTSLVAVTGASNVTGEVPPLAEIVRLARAAGARVFVDGAQLVPHRRVDM
AALGIDYLAFSGHKLYAPFGAGVLVGRPDWLAAAPPYLAGGGAVREVTNSAVAWADGPARHEAGSPNLLGATAIAAACRL
LGALAPRDLHQHEDLLRRRLVDGLRAIEGVTIHSLWADGDDPAAGEAAGGEGPDGILATGPVGVVTFSVAGRDPGFVAAV
LSAEHGVGVRAGRFCAHPLLGRLGAEGGAIRASVGISSTSADVDRLLAGLAELVGRGPRQQYRDLGDGGWAPASDGRALP
PWVAEHMAAGHVRGRVPAPGHAHDSAGLPAYSSPCGT

Specific function: Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=439, Percent_Identity=32.1184510250569, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1789175, Length=411, Percent_Identity=34.3065693430657, Blast_Score=171, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI193211090, Length=434, Percent_Identity=25.8064516129032, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7; =4.4.1.16 [H]

Molecular weight: Translated: 53054; Mature: 52923

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSYATTSPDVDREGPAVGALLDVVGAGIPVPLADGREVPYANLDQAASAPCLRGVAEH
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHH
VERVLPYSASVHRGTGYSSAVCTALYEGARAAVRTFVGGRPDDVVIFTRNTTDSVNLLAR
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
CLPPQPPDPPQPPDPARTSDPGHAEPGGVVVFDLEHHANLLPWRSRPGCRWVPAAPTRAD
HCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCHHH
TLRALATALDTAPTSLVAVTGASNVTGEVPPLAEIVRLARAAGARVFVDGAQLVPHRRVD
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHCCCCCHH
MAALGIDYLAFSGHKLYAPFGAGVLVGRPDWLAAAPPYLAGGGAVREVTNSAVAWADGPA
HHHHHHHHHEECCCEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCEEECCCCH
RHEAGSPNLLGATAIAAACRLLGALAPRDLHQHEDLLRRRLVDGLRAIEGVTIHSLWADG
HCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
DDPAAGEAAGGEGPDGILATGPVGVVTFSVAGRDPGFVAAVLSAEHGVGVRAGRFCAHPL
CCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHH
LGRLGAEGGAIRASVGISSTSADVDRLLAGLAELVGRGPRQQYRDLGDGGWAPASDGRAL
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCC
PPWVAEHMAAGHVRGRVPAPGHAHDSAGLPAYSSPCGT
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLSYATTSPDVDREGPAVGALLDVVGAGIPVPLADGREVPYANLDQAASAPCLRGVAEH
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHH
VERVLPYSASVHRGTGYSSAVCTALYEGARAAVRTFVGGRPDDVVIFTRNTTDSVNLLAR
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
CLPPQPPDPPQPPDPARTSDPGHAEPGGVVVFDLEHHANLLPWRSRPGCRWVPAAPTRAD
HCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCHHH
TLRALATALDTAPTSLVAVTGASNVTGEVPPLAEIVRLARAAGARVFVDGAQLVPHRRVD
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHCCCCCHH
MAALGIDYLAFSGHKLYAPFGAGVLVGRPDWLAAAPPYLAGGGAVREVTNSAVAWADGPA
HHHHHHHHHEECCCEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCEEECCCCH
RHEAGSPNLLGATAIAAACRLLGALAPRDLHQHEDLLRRRLVDGLRAIEGVTIHSLWADG
HCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
DDPAAGEAAGGEGPDGILATGPVGVVTFSVAGRDPGFVAAVLSAEHGVGVRAGRFCAHPL
CCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHH
LGRLGAEGGAIRASVGISSTSADVDRLLAGLAELVGRGPRQQYRDLGDGGWAPASDGRAL
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCC
PPWVAEHMAAGHVRGRVPAPGHAHDSAGLPAYSSPCGT
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11251816 [H]