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The map label for this gene is prcA

Identifier: 158316641

GI number: 158316641

Start: 5851972

End: 5852691

Strand: Reverse

Name: prcA

Synonym: Franean1_4878

Alternate gene names: 158316641

Gene position: 5852691-5851972 (Counterclockwise)

Preceding gene: 158316642

Following gene: 158316638

Centisome position: 65.16

GC content: 68.75

Gene sequence:

>720_bases
ATGCCGTTCGGCTACGCAAGTCCCGAACAGCAGGTCCGGGACAAGTCCGAGTACGCGCGCAAGGGCATCGCGCGCGGCCG
GAGCGTGGTCGTCCTCACCTACGTCGACGGCATCCTGTTCGTCGCCGAGAACCCGTCGACGACCCTGCACAAGATCAGCG
AGATGTACGACCGCATCGGCTTCGCCGCGGTGGGGAAGTACAACGAGTTCGAGAACCTCCGCACGGCCGGCATCCGGATC
ATGGACACCCGCGGCTACATGTACGACCGGCGGGATGTCACGAGCCGGGCGCTCGCGAACGCCTACGCGCAGACCCTCGG
CGCGATCTTCACTGAGAGCATCAAGCCCTACGAGGTGGAGATCGTCGTCGCCGAGGTGGGGCACACCGCCGCGGATGACC
AGATCTTCCGTCTCACCTACGACGGCTCGATCGCCGACGAGCGTGGCTTCATCGCGATCGGCGGTCAGTCCGAGCAGGTG
CTGACCTCCCTGCGGGAGCACCACACGGAGGGCCAGCCGCTCGCCACCGCGCTGCGCGTGGCGGTGGACGCGCTCACCGC
CGGCGCGCCGCCCGGGGCGCAGAACGGGGAGCGCACGCTGACGGCCGGGAACCTCGAGGTCGCGATGCTCGACCGGAAGC
GCTCCCGGCGGTTGTTCAAGCGGATCGTCGGCAGCCAGCTCGACGGACTGCTCGAGGAGACCGCTCCGTCCGCGTCCTGA

Upstream 100 bases:

>100_bases
ACCGTCGACGGATACCGTCGCCTCACCGATGACGAGGTCGGCCCGGTGGTCGACTCGATCATCGCCGACCGCGCGCAGAA
CTCAGGAGGCTGACGTGACC

Downstream 100 bases:

>100_bases
CGAGCCGGATCGGGAGTCTCCGCCGGCCGAGGTGCCTTCTCGGCCGGCACGGCTTGGCTTCGGATCCGATCCGTGGCCGT
TCCGCAGGGCTCACACAGCC

Product: 20S proteasome subunits A and B

Products: NA

Alternate protein names: 20S proteasome alpha subunit; Proteasome core protein PrcA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MPFGYASPEQQVRDKSEYARKGIARGRSVVVLTYVDGILFVAENPSTTLHKISEMYDRIGFAAVGKYNEFENLRTAGIRI
MDTRGYMYDRRDVTSRALANAYAQTLGAIFTESIKPYEVEIVVAEVGHTAADDQIFRLTYDGSIADERGFIAIGGQSEQV
LTSLREHHTEGQPLATALRVAVDALTAGAPPGAQNGERTLTAGNLEVAMLDRKRSRRLFKRIVGSQLDGLLEETAPSAS

Sequences:

>Translated_239_residues
MPFGYASPEQQVRDKSEYARKGIARGRSVVVLTYVDGILFVAENPSTTLHKISEMYDRIGFAAVGKYNEFENLRTAGIRI
MDTRGYMYDRRDVTSRALANAYAQTLGAIFTESIKPYEVEIVVAEVGHTAADDQIFRLTYDGSIADERGFIAIGGQSEQV
LTSLREHHTEGQPLATALRVAVDALTAGAPPGAQNGERTLTAGNLEVAMLDRKRSRRLFKRIVGSQLDGLLEETAPSAS
>Mature_238_residues
PFGYASPEQQVRDKSEYARKGIARGRSVVVLTYVDGILFVAENPSTTLHKISEMYDRIGFAAVGKYNEFENLRTAGIRIM
DTRGYMYDRRDVTSRALANAYAQTLGAIFTESIKPYEVEIVVAEVGHTAADDQIFRLTYDGSIADERGFIAIGGQSEQVL
TSLREHHTEGQPLATALRVAVDALTAGAPPGAQNGERTLTAGNLEVAMLDRKRSRRLFKRIVGSQLDGLLEETAPSAS

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSA_FRASN (A8LH53)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001509149.1
- GeneID:   5673218
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_4878
- HOGENOM:   HBG292323
- OMA:   AVGKYNE
- ProtClustDB:   CLSK872007
- BioCyc:   FSP1855:FRANEAN1_4878-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00289_B
- InterPro:   IPR022296
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03691

Pfam domain/function: PF00227 Proteasome

EC number: =3.4.25.1

Molecular weight: Translated: 26190; Mature: 26059

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00388 PROTEASOME_A_1; PS51475 PROTEASOME_A_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFGYASPEQQVRDKSEYARKGIARGRSVVVLTYVDGILFVAENPSTTLHKISEMYDRIG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHC
FAAVGKYNEFENLRTAGIRIMDTRGYMYDRRDVTSRALANAYAQTLGAIFTESIKPYEVE
HHHHCCCHHHHHHHHHCEEEEECCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IVVAEVGHTAADDQIFRLTYDGSIADERGFIAIGGQSEQVLTSLREHHTEGQPLATALRV
EEEEECCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHH
AVDALTAGAPPGAQNGERTLTAGNLEVAMLDRKRSRRLFKRIVGSQLDGLLEETAPSAS
HHHHHHCCCCCCCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PFGYASPEQQVRDKSEYARKGIARGRSVVVLTYVDGILFVAENPSTTLHKISEMYDRIG
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHC
FAAVGKYNEFENLRTAGIRIMDTRGYMYDRRDVTSRALANAYAQTLGAIFTESIKPYEVE
HHHHCCCHHHHHHHHHCEEEEECCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IVVAEVGHTAADDQIFRLTYDGSIADERGFIAIGGQSEQVLTSLREHHTEGQPLATALRV
EEEEECCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHH
AVDALTAGAPPGAQNGERTLTAGNLEVAMLDRKRSRRLFKRIVGSQLDGLLEETAPSAS
HHHHHHCCCCCCCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA