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The map label for this gene is fkpA [C]

Identifier: 158316636

GI number: 158316636

Start: 5846346

End: 5846978

Strand: Reverse

Name: fkpA [C]

Synonym: Franean1_4873

Alternate gene names: 158316636

Gene position: 5846978-5846346 (Counterclockwise)

Preceding gene: 158316637

Following gene: 158316635

Centisome position: 65.1

GC content: 73.78

Gene sequence:

>633_bases
GTGATCTCTTCGCTTCGTGGTGTCATCGCCCGCCGCCGTCACCGGCTGGCCGCCCTCGCCCTCCCCGCCGTCCTGCTGGT
GCCGCTCGCCGCGTGCAGCTCGTCGGACACGCCCGACGGGACGGCCGCCGCGCCGGTCCCGTCCGCCGCGCAGGACGCCG
GCGCGCGGGCGGGCGGCCCGCCGGCCGTCGAGAATGCCGTGGACCTCACCCAGAAGCCCGTAGCCGCGGCGGGCAAGGGC
CTGGCCCCGACCGACCTGGTCACCCAGGATCTGGTGACCGGTGAGGGCGCGGCGGCCAGCGCGACGAGCACCGTCCAGAT
CCAGTACGTCGGCACCATCTGGAAGACCGGCAAGGAGTTCGACTCGAGCTGGGAGCGGGGCGCCCCGGACACCTTCTCCC
TGCTGCGGACGGTCCCCGGCTTCGGCCAGGGCATCGACGGGATGAAGGCGGGCGGCCGCCGGCTGATCGTGATCCCGCCG
GAGCTCGGCTACGGGCCGATGGGCGGCCAGCCGCCGATAATCATGGCTGATGACTCGCTGGTGTTCATCGTCGACCTGCT
CGAGGTCGTGCCGGCCGGCGCCGAAGAGGGCACGTCGCAGGGCACGGCCGATCCGGGGACCGGGTCTCTCTGA

Upstream 100 bases:

>100_bases
TGACTCCACAGGTTCAGGCAGCTCGAGCGCGTGGCGCCGGCCGGCGGCCCCGCGTGCCGTGGCGGCGGTGCCGCGCAGTA
TCCAGAGGATCTTTGCTTCC

Downstream 100 bases:

>100_bases
CGCGTCGCGTCGCCGCCCCGGCCGGGCAAGCCCTGGCCGGGGCCACGACGGTCCTCGCCGCCCCGCGGCGGCGGCGGGGC
GGTTACCACGTTGACGTCGA

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MISSLRGVIARRRHRLAALALPAVLLVPLAACSSSDTPDGTAAAPVPSAAQDAGARAGGPPAVENAVDLTQKPVAAAGKG
LAPTDLVTQDLVTGEGAAASATSTVQIQYVGTIWKTGKEFDSSWERGAPDTFSLLRTVPGFGQGIDGMKAGGRRLIVIPP
ELGYGPMGGQPPIIMADDSLVFIVDLLEVVPAGAEEGTSQGTADPGTGSL

Sequences:

>Translated_210_residues
MISSLRGVIARRRHRLAALALPAVLLVPLAACSSSDTPDGTAAAPVPSAAQDAGARAGGPPAVENAVDLTQKPVAAAGKG
LAPTDLVTQDLVTGEGAAASATSTVQIQYVGTIWKTGKEFDSSWERGAPDTFSLLRTVPGFGQGIDGMKAGGRRLIVIPP
ELGYGPMGGQPPIIMADDSLVFIVDLLEVVPAGAEEGTSQGTADPGTGSL
>Mature_210_residues
MISSLRGVIARRRHRLAALALPAVLLVPLAACSSSDTPDGTAAAPVPSAAQDAGARAGGPPAVENAVDLTQKPVAAAGKG
LAPTDLVTQDLVTGEGAAASATSTVQIQYVGTIWKTGKEFDSSWERGAPDTFSLLRTVPGFGQGIDGMKAGGRRLIVIPP
ELGYGPMGGQPPIIMADDSLVFIVDLLEVVPAGAEEGTSQGTADPGTGSL

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789745, Length=127, Percent_Identity=40.9448818897638, Blast_Score=76, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647110, Length=99, Percent_Identity=38.3838383838384, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21136; Mature: 21136

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSLRGVIARRRHRLAALALPAVLLVPLAACSSSDTPDGTAAAPVPSAAQDAGARAGGP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCC
PAVENAVDLTQKPVAAAGKGLAPTDLVTQDLVTGEGAAASATSTVQIQYVGTIWKTGKEF
CHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHCCHHH
DSSWERGAPDTFSLLRTVPGFGQGIDGMKAGGRRLIVIPPELGYGPMGGQPPIIMADDSL
HHHHCCCCCHHHHHHHHCCCCCCCCCCHHCCCCEEEEECCCCCCCCCCCCCCEEEECCCH
VFIVDLLEVVPAGAEEGTSQGTADPGTGSL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MISSLRGVIARRRHRLAALALPAVLLVPLAACSSSDTPDGTAAAPVPSAAQDAGARAGGP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCC
PAVENAVDLTQKPVAAAGKGLAPTDLVTQDLVTGEGAAASATSTVQIQYVGTIWKTGKEF
CHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHCCHHH
DSSWERGAPDTFSLLRTVPGFGQGIDGMKAGGRRLIVIPPELGYGPMGGQPPIIMADDSL
HHHHCCCCCHHHHHHHHCCCCCCCCCCHHCCCCEEEEECCCCCCCCCCCCCCEEEECCCH
VFIVDLLEVVPAGAEEGTSQGTADPGTGSL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7522844; 12948626 [H]