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The map label for this gene is ksdD [H]

Identifier: 158316483

GI number: 158316483

Start: 5632068

End: 5633762

Strand: Reverse

Name: ksdD [H]

Synonym: Franean1_4718

Alternate gene names: 158316483

Gene position: 5633762-5632068 (Counterclockwise)

Preceding gene: 158316484

Following gene: 158316482

Centisome position: 62.72

GC content: 68.5

Gene sequence:

>1695_bases
GTGTCGAAGTCGGATGCCAGCTACGACCATGCCGTTGACGTCATTGTCGTGGGATCGGGCGGTGGTCTGTGCGGCGCCGT
GGCCGCGGCGGCGAGCGGCCTGGACACGCTGGTGATCGAGAAGCAGCCGATGATCGGCGGGTCCACGGCCATGTCAGGCG
GCGTGCTGTGGCTGCCGGACAACCCGCTCATGCAGGCCGACGACGTTCCCGACTCCCTTGAGGACGCGCTGGCGTACTTC
GACTCCGTTGTCGGAGACGTCGGTCCCGCGTCGTCGCACCAGCGTCGGGTCGCCTACGTCACCGAAGGCGCCACCATGGT
CCGCTTCCTGCAGAACCTGGGCATGCGGTTCGAGCGGTGCGAGGGCTACAGCGACTACTACGCCGGGGTGGCGGGTATCC
GCGGCGGCAGCGCCCGCGGGCGCTCCCTCGAACCCGCGGTGACCGACGGCAAACAGCTCGGGCCGTGGTTCGACAAGCTG
ATGCCGGGCATGACGATCGCGCTCGGGATCGTCGTGATGACACGCGAGGCGTCCGGACTGCAGATGGTCAAGCGGCGACC
GAAAGCCATGCGCACCGCCGCCCGCGTCGGGGTGCGCACGGCCATCGGCCGGCTACGGCGCCAGACCCGCCTGGCCAACG
GCGGGGCACTGATCGCCCAGACCCTGACGGCCGCACTCGCCGCCGGGGCGTCGATTTGGACGAACACCGGACTGGTCGAC
CTGATCACCGAGGACGGCCGGGTCGTCGGCGTCGTCGCCGACCGGGACGGCCACACCATCCGGATCCGCGCCCGCCACGC
CGTGCTGTTGAGCTCAGGTGGTTTCGGCTGCAACCCCGAGATGCGCAAGCGGTACTCGAAGCAGCCGAACGACGGAACGT
GGACCAGTGCCAACCCGGGTGACACCGGCGAGGCGATCGAGGCCGCCATGCGCCTGGGCGCCGCCGTCGACTTCATGGAC
GAGGCCCTGTGGATCCCGGCCTCCATCCAGCCCGGCGGACGTCCGAGCATGCACAACGGCGAACGATGCAAACCAGGTTC
GATCATCGTCGACCGGGCCGGCCGCCGGTACTTCAACGAAGCGGTCTCCTACATGGAAGCCGGCCGGCAGATGTACGCCC
ACAACGTCGACGGTGAATCCATCCCGAGCTGGCTCGTCATGGACTCCCGCCACCGCGCCCGCTACCTGTTCGCGTTCCGT
CCCAACACTCCCGAGGAATGGCTCACCAGCGGCTACATGAAGAAAGCCGACACGCTCGACGAGCTCGCGCGGGCGTGCGG
CATCGACCCCGCGGGGCTGGCCACCACGGTGGCCCGGTTCAACACGTTCGCGGAGCAGGGCACGGACCCCGACTTCCACC
GCGGCGAAGGCGCTCATGAAAAGTACCAGGGCGACTACGGCAACAAACCGAACCCGTCGCTCGCGCCCGTCGAGAAGGCA
CCATTCTACGCCGTCGAACTCTATCCAGGCGACGTCGGCACCAGCGGCGGTCTCCTGTGCGACGAACATGCTCGTGTGCT
CGACACCAACCACGACCCGATCCCCGGCCTCTACGCCGCCGGGAACTGCACCGCCTCGGTGATGGGCCGCACCTATCTCG
GTGCGGGCGCCAGCATCGGCAACAGCTTCGTGTTCTCCTACATCGGCATGAAACACGCCGCACACGCCGCCTCCGGGGAC
CGAGCGGTCACGTGA

Upstream 100 bases:

>100_bases
CGAGATGGAGCAGCTCATCAGCAACATGCACTCCGAACTCGACCGGTACCTCGCCGGCTGAGGCACCGCACCGAAACCAT
CCACTCCATGGAGGGGCACC

Downstream 100 bases:

>100_bases
CCGCAGAACGGAGCGCACGGCCCCGGGGGCCAGTGGTACGCATCGACCCCGTCGGCGCCGACCTCGAACTCGAACCCGGA
GAGACGATCATCGAGGCCGC

Product: 3-ketosteroid-delta-1-dehydrogenase

Products: NA

Alternate protein names: 3-keto-Delta(4)-steroid Delta(1)-dehydrogenase; KSDD; 3-oxo-Delta(4)-steroid 1-dehydrogenase; KSTD [H]

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MSKSDASYDHAVDVIVVGSGGGLCGAVAAAASGLDTLVIEKQPMIGGSTAMSGGVLWLPDNPLMQADDVPDSLEDALAYF
DSVVGDVGPASSHQRRVAYVTEGATMVRFLQNLGMRFERCEGYSDYYAGVAGIRGGSARGRSLEPAVTDGKQLGPWFDKL
MPGMTIALGIVVMTREASGLQMVKRRPKAMRTAARVGVRTAIGRLRRQTRLANGGALIAQTLTAALAAGASIWTNTGLVD
LITEDGRVVGVVADRDGHTIRIRARHAVLLSSGGFGCNPEMRKRYSKQPNDGTWTSANPGDTGEAIEAAMRLGAAVDFMD
EALWIPASIQPGGRPSMHNGERCKPGSIIVDRAGRRYFNEAVSYMEAGRQMYAHNVDGESIPSWLVMDSRHRARYLFAFR
PNTPEEWLTSGYMKKADTLDELARACGIDPAGLATTVARFNTFAEQGTDPDFHRGEGAHEKYQGDYGNKPNPSLAPVEKA
PFYAVELYPGDVGTSGGLLCDEHARVLDTNHDPIPGLYAAGNCTASVMGRTYLGAGASIGNSFVFSYIGMKHAAHAASGD
RAVT

Sequences:

>Translated_564_residues
MSKSDASYDHAVDVIVVGSGGGLCGAVAAAASGLDTLVIEKQPMIGGSTAMSGGVLWLPDNPLMQADDVPDSLEDALAYF
DSVVGDVGPASSHQRRVAYVTEGATMVRFLQNLGMRFERCEGYSDYYAGVAGIRGGSARGRSLEPAVTDGKQLGPWFDKL
MPGMTIALGIVVMTREASGLQMVKRRPKAMRTAARVGVRTAIGRLRRQTRLANGGALIAQTLTAALAAGASIWTNTGLVD
LITEDGRVVGVVADRDGHTIRIRARHAVLLSSGGFGCNPEMRKRYSKQPNDGTWTSANPGDTGEAIEAAMRLGAAVDFMD
EALWIPASIQPGGRPSMHNGERCKPGSIIVDRAGRRYFNEAVSYMEAGRQMYAHNVDGESIPSWLVMDSRHRARYLFAFR
PNTPEEWLTSGYMKKADTLDELARACGIDPAGLATTVARFNTFAEQGTDPDFHRGEGAHEKYQGDYGNKPNPSLAPVEKA
PFYAVELYPGDVGTSGGLLCDEHARVLDTNHDPIPGLYAAGNCTASVMGRTYLGAGASIGNSFVFSYIGMKHAAHAASGD
RAVT
>Mature_563_residues
SKSDASYDHAVDVIVVGSGGGLCGAVAAAASGLDTLVIEKQPMIGGSTAMSGGVLWLPDNPLMQADDVPDSLEDALAYFD
SVVGDVGPASSHQRRVAYVTEGATMVRFLQNLGMRFERCEGYSDYYAGVAGIRGGSARGRSLEPAVTDGKQLGPWFDKLM
PGMTIALGIVVMTREASGLQMVKRRPKAMRTAARVGVRTAIGRLRRQTRLANGGALIAQTLTAALAAGASIWTNTGLVDL
ITEDGRVVGVVADRDGHTIRIRARHAVLLSSGGFGCNPEMRKRYSKQPNDGTWTSANPGDTGEAIEAAMRLGAAVDFMDE
ALWIPASIQPGGRPSMHNGERCKPGSIIVDRAGRRYFNEAVSYMEAGRQMYAHNVDGESIPSWLVMDSRHRARYLFAFRP
NTPEEWLTSGYMKKADTLDELARACGIDPAGLATTVARFNTFAEQGTDPDFHRGEGAHEKYQGDYGNKPNPSLAPVEKAP
FYAVELYPGDVGTSGGLLCDEHARVLDTNHDPIPGLYAAGNCTASVMGRTYLGAGASIGNSFVFSYIGMKHAAHAASGDR
AVT

Specific function: Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3- ketosteroids. Is also involved in the formation of 1,4- androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=351, Percent_Identity=27.0655270655271, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.3.99.4 [H]

Molecular weight: Translated: 60044; Mature: 59913

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSDASYDHAVDVIVVGSGGGLCGAVAAAASGLDTLVIEKQPMIGGSTAMSGGVLWLPD
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEECCC
NPLMQADDVPDSLEDALAYFDSVVGDVGPASSHQRRVAYVTEGATMVRFLQNLGMRFERC
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCHHHHH
EGYSDYYAGVAGIRGGSARGRSLEPAVTDGKQLGPWFDKLMPGMTIALGIVVMTREASGL
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEECCCCCH
QMVKRRPKAMRTAARVGVRTAIGRLRRQTRLANGGALIAQTLTAALAAGASIWTNTGLVD
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCEEE
LITEDGRVVGVVADRDGHTIRIRARHAVLLSSGGFGCNPEMRKRYSKQPNDGTWTSANPG
EEECCCEEEEEEECCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCC
DTGEAIEAAMRLGAAVDFMDEALWIPASIQPGGRPSMHNGERCKPGSIIVDRAGRRYFNE
CCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHH
AVSYMEAGRQMYAHNVDGESIPSWLVMDSRHRARYLFAFRPNTPEEWLTSGYMKKADTLD
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
ELARACGIDPAGLATTVARFNTFAEQGTDPDFHRGEGAHEKYQGDYGNKPNPSLAPVEKA
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCC
PFYAVELYPGDVGTSGGLLCDEHARVLDTNHDPIPGLYAAGNCTASVMGRTYLGAGASIG
CEEEEEEECCCCCCCCCEEECCCHHHCCCCCCCCCCEEECCCCHHHHHCCHHHCCCCHHH
NSFVFSYIGMKHAAHAASGDRAVT
HHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKSDASYDHAVDVIVVGSGGGLCGAVAAAASGLDTLVIEKQPMIGGSTAMSGGVLWLPD
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEECCC
NPLMQADDVPDSLEDALAYFDSVVGDVGPASSHQRRVAYVTEGATMVRFLQNLGMRFERC
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHCCHHHHH
EGYSDYYAGVAGIRGGSARGRSLEPAVTDGKQLGPWFDKLMPGMTIALGIVVMTREASGL
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEECCCCCH
QMVKRRPKAMRTAARVGVRTAIGRLRRQTRLANGGALIAQTLTAALAAGASIWTNTGLVD
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCEEE
LITEDGRVVGVVADRDGHTIRIRARHAVLLSSGGFGCNPEMRKRYSKQPNDGTWTSANPG
EEECCCEEEEEEECCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCC
DTGEAIEAAMRLGAAVDFMDEALWIPASIQPGGRPSMHNGERCKPGSIIVDRAGRRYFNE
CCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHH
AVSYMEAGRQMYAHNVDGESIPSWLVMDSRHRARYLFAFRPNTPEEWLTSGYMKKADTLD
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
ELARACGIDPAGLATTVARFNTFAEQGTDPDFHRGEGAHEKYQGDYGNKPNPSLAPVEKA
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCC
PFYAVELYPGDVGTSGGLLCDEHARVLDTNHDPIPGLYAAGNCTASVMGRTYLGAGASIG
CEEEEEEECCCCCCCCCEEECCCHHHCCCCCCCCCCEEECCCCHHHHHCCHHHCCCCHHH
NSFVFSYIGMKHAAHAASGDRAVT
HHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA