| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is caiD [H]
Identifier: 158316338
GI number: 158316338
Start: 5449854
End: 5450618
Strand: Reverse
Name: caiD [H]
Synonym: Franean1_4567
Alternate gene names: 158316338
Gene position: 5450618-5449854 (Counterclockwise)
Preceding gene: 158316339
Following gene: 158316337
Centisome position: 60.68
GC content: 74.77
Gene sequence:
>765_bases ATGGCAGACTCGGTGCTGGTCGAGCGGCATGACGCCGTCCTGGTCATCACGATCAACCGCCCGGAGGCCAGGAACGCGCT CGACGCCGAGGCCGCGCGCGGCATCGCGGCGGCAGCGGACGAGTTGGACGGCGACCCGCAGCTGCGGGTCGGTGTGCTGA CCGGGGCCGGCGGCTCGTTCTGTGCCGGCATGGATCTGAAGGCCTTCCTGCGCGGTGAGACCCCCAACATCAAGGGCCGC GGTTTCGGCGGCATCACCGTCACGCCACCGCGCAAGCCGCTGATCGCCGCGGTGGAGGGCTGGGCGCTGGCCGGCGGCTT CGAGCTGCTGCTGGCGTGCGACCTGGTCGTGGCCGCGGCGACGAGCAGGTTCGGCGTGCCGGAGGTCAAGCGCGCGCTGG TGGCCGGCGGCGGCGCGGCGATGCTGCTGCCGCGCCGGATCGCCTTCTCGGTCGCGCTGGAGCTCCTGCTGACCGGTGAG CCCGTGACGGCGGAGCGGGCGGCAGCGCTGGGGCTGGTCAACCGGGTCGTGCCGGAGGGTGGCGCGCTGGCCGGGGCGCT CGAACTCGCGGCCAAGATCGCCGCCAACGGGCCGTTGGCCGTGGCGACGACCAAGCAGATCGCCCGGGCGCAGGCCGACT GGACGGCCGAGGAGGGCTGGCAGCGGCAGGCCGAGCTGTGCGCCCCGGTCTTCGCCTCCGAGGATGCCCGCGAGGGCGCG ACCGCCTTCGCCGAGAAGCGCCCCCCGGTGTGGCTCGGCCGGTGA
Upstream 100 bases:
>100_bases CGCACCGCGAGAACTGCAACCGCGACAGCTTCGATCGCGAGAACTGCGACCGCGAGAACTTGGGCCGCGAGAACTTGGGC CGCGAGAACGAGGAGACGGC
Downstream 100 bases:
>100_bases CGGCGCGCTCCGTCGGGTGACCCGCGGTGCCGCGCCGCTCGAGGCCGGCCACCGGGCCGGCACCGAGCGACACCGGGCAG GGGCACCACAGGAACGCCAT
Product: enoyl-CoA hydratase/isomerase
Products: L-Carnitine.; L-carnitinyl-CoA [C]
Alternate protein names: Crotonobetainyl-CoA hydratase [H]
Number of amino acids: Translated: 254; Mature: 253
Protein sequence:
>254_residues MADSVLVERHDAVLVITINRPEARNALDAEAARGIAAAADELDGDPQLRVGVLTGAGGSFCAGMDLKAFLRGETPNIKGR GFGGITVTPPRKPLIAAVEGWALAGGFELLLACDLVVAAATSRFGVPEVKRALVAGGGAAMLLPRRIAFSVALELLLTGE PVTAERAAALGLVNRVVPEGGALAGALELAAKIAANGPLAVATTKQIARAQADWTAEEGWQRQAELCAPVFASEDAREGA TAFAEKRPPVWLGR
Sequences:
>Translated_254_residues MADSVLVERHDAVLVITINRPEARNALDAEAARGIAAAADELDGDPQLRVGVLTGAGGSFCAGMDLKAFLRGETPNIKGR GFGGITVTPPRKPLIAAVEGWALAGGFELLLACDLVVAAATSRFGVPEVKRALVAGGGAAMLLPRRIAFSVALELLLTGE PVTAERAAALGLVNRVVPEGGALAGALELAAKIAANGPLAVATTKQIARAQADWTAEEGWQRQAELCAPVFASEDAREGA TAFAEKRPPVWLGR >Mature_253_residues ADSVLVERHDAVLVITINRPEARNALDAEAARGIAAAADELDGDPQLRVGVLTGAGGSFCAGMDLKAFLRGETPNIKGRG FGGITVTPPRKPLIAAVEGWALAGGFELLLACDLVVAAATSRFGVPEVKRALVAGGGAAMLLPRRIAFSVALELLLTGEP VTAERAAALGLVNRVVPEGGALAGALELAAKIAANGPLAVATTKQIARAQADWTAEEGWQRQAELCAPVFASEDAREGAT AFAEKRPPVWLGR
Specific function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA [H]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=241, Percent_Identity=34.0248962655602, Blast_Score=137, Evalue=9e-33, Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=32.5581395348837, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI31542718, Length=249, Percent_Identity=29.3172690763052, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI70995211, Length=260, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI68989263, Length=170, Percent_Identity=32.3529411764706, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI25453481, Length=252, Percent_Identity=23.4126984126984, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI51538573, Length=252, Percent_Identity=23.4126984126984, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI221136756, Length=253, Percent_Identity=23.7154150197628, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI221136753, Length=253, Percent_Identity=23.7154150197628, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI221307494, Length=253, Percent_Identity=23.7154150197628, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4757966, Length=238, Percent_Identity=23.9495798319328, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI51538581, Length=238, Percent_Identity=23.9495798319328, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4757968, Length=253, Percent_Identity=23.3201581027668, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI49355787, Length=253, Percent_Identity=23.3201581027668, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI260274832, Length=218, Percent_Identity=27.5229357798165, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI45643119, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI260275230, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI20127408, Length=187, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=4e-13, Organism=Escherichia coli, GI221142681, Length=262, Percent_Identity=41.2213740458015, Blast_Score=170, Evalue=7e-44, Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=36.8217054263566, Blast_Score=150, Evalue=8e-38, Organism=Escherichia coli, GI87082183, Length=251, Percent_Identity=31.4741035856574, Blast_Score=110, Evalue=8e-26, Organism=Escherichia coli, GI1788597, Length=250, Percent_Identity=32, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1788682, Length=194, Percent_Identity=37.1134020618557, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=29.3893129770992, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1790281, Length=205, Percent_Identity=28.780487804878, Blast_Score=70, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17554946, Length=241, Percent_Identity=37.344398340249, Blast_Score=150, Evalue=4e-37, Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=37.037037037037, Blast_Score=149, Evalue=1e-36, Organism=Caenorhabditis elegans, GI17560910, Length=248, Percent_Identity=33.8709677419355, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17540714, Length=236, Percent_Identity=34.7457627118644, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17534483, Length=254, Percent_Identity=27.5590551181102, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17558304, Length=228, Percent_Identity=27.6315789473684, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17540306, Length=257, Percent_Identity=29.1828793774319, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536985, Length=261, Percent_Identity=24.5210727969349, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17508953, Length=242, Percent_Identity=28.5123966942149, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI25144276, Length=242, Percent_Identity=28.5123966942149, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17508951, Length=242, Percent_Identity=28.5123966942149, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17535521, Length=256, Percent_Identity=25, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17549921, Length=238, Percent_Identity=26.4705882352941, Blast_Score=75, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6320241, Length=188, Percent_Identity=27.6595744680851, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI20129971, Length=237, Percent_Identity=37.1308016877637, Blast_Score=142, Evalue=2e-34, Organism=Drosophila melanogaster, GI24653477, Length=237, Percent_Identity=37.1308016877637, Blast_Score=142, Evalue=2e-34, Organism=Drosophila melanogaster, GI21357171, Length=272, Percent_Identity=34.9264705882353, Blast_Score=127, Evalue=7e-30, Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=36.6037735849057, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI24650670, Length=198, Percent_Identity=37.8787878787879, Blast_Score=117, Evalue=7e-27, Organism=Drosophila melanogaster, GI19922422, Length=260, Percent_Identity=29.2307692307692, Blast_Score=100, Evalue=7e-22, Organism=Drosophila melanogaster, GI19920382, Length=260, Percent_Identity=29.2307692307692, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI24654903, Length=181, Percent_Identity=28.7292817679558, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24583077, Length=176, Percent_Identity=35.2272727272727, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI24583079, Length=176, Percent_Identity=35.2272727272727, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI19921000, Length=176, Percent_Identity=35.2272727272727, Blast_Score=77, Evalue=2e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022852 - InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: 4.2.1.- [C]
Molecular weight: Translated: 26144; Mature: 26013
Theoretical pI: Translated: 5.17; Mature: 5.17
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADSVLVERHDAVLVITINRPEARNALDAEAARGIAAAADELDGDPQLRVGVLTGAGGSF CCCCEEEECCCEEEEEEECCCCCCCCHHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCCE CAGMDLKAFLRGETPNIKGRGFGGITVTPPRKPLIAAVEGWALAGGFELLLACDLVVAAA EECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCEEEEECCEEEHHHHHHHHHHHHHHHHH TSRFGVPEVKRALVAGGGAAMLLPRRIAFSVALELLLTGEPVTAERAAALGLVNRVVPEG HCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC GALAGALELAAKIAANGPLAVATTKQIARAQADWTAEEGWQRQAELCAPVFASEDAREGA CHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCH TAFAEKRPPVWLGR HHHHHCCCCCCCCC >Mature Secondary Structure ADSVLVERHDAVLVITINRPEARNALDAEAARGIAAAADELDGDPQLRVGVLTGAGGSF CCCEEEECCCEEEEEEECCCCCCCCHHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCCE CAGMDLKAFLRGETPNIKGRGFGGITVTPPRKPLIAAVEGWALAGGFELLLACDLVVAAA EECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCEEEEECCEEEHHHHHHHHHHHHHHHHH TSRFGVPEVKRALVAGGGAAMLLPRRIAFSVALELLLTGEPVTAERAAALGLVNRVVPEG HCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC GALAGALELAAKIAANGPLAVATTKQIARAQADWTAEEGWQRQAELCAPVFASEDAREGA CHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCH TAFAEKRPPVWLGR HHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: D-Carnitine; D-carnitinyl-CoA [C]
Specific reaction: D-Carnitine = L-Carnitine. D-carnitinyl-CoA = L-carnitinyl-CoA [C]
General reaction: Isomerases [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA