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The map label for this gene is sbm [H]

Identifier: 158316091

GI number: 158316091

Start: 5147684

End: 5148085

Strand: Reverse

Name: sbm [H]

Synonym: Franean1_4309

Alternate gene names: 158316091

Gene position: 5148085-5147684 (Counterclockwise)

Preceding gene: 158316092

Following gene: 158316090

Centisome position: 57.32

GC content: 74.38

Gene sequence:

>402_bases
ATGCCGGCGCGGGTACTGGTCGCCAAGCCCGGCCTGGACGGGCACGACCGCGGGGCCAAGATCGTCGCGCGGGCGTTGCG
CGACGCCGGCTTCGAGGTCGTGTTCACCGGCATCCGGCAGCGCGTCGAGGACATCGTGACCATCGCGCTGCAGGAGGACG
TCGCGGTCGTCGGGCTGAGCATCCTCTCCGGCGCGCACATCGCGCTGACCACGCGCACCATCGAGGCGCTGCGGGCGGCG
GACGCCGGCGACATCGCCGTCGTCGTCGGCGGCACCATCCCGCCGGCGGACGTCCCCAGACTGCTCGAGGTGGGCGCCGC
CGGGGTGTTCCCGACCGGCACCCCGCTCGAGCAGCTGGTCACCGAGGTCCGCGCGCTGACCTCGACACCCACCGCGCCCT
GA

Upstream 100 bases:

>100_bases
ACAACCTGATCGACTGCGCCAACGCCTACTGCACGGTGGGCGAGATGGTCGCCACCCTCAAGAACGTCTGGGGCGAGTTC
CAGCAGCCGGTGGTGTTCTG

Downstream 100 bases:

>100_bases
TCCGGGGTACGGCGCAGCGAGACATCGGAAACATTCGAGACCTGGAGGGGTCCAGTGCGGGTCGGCGTGATGATCGGACC
GGAGCGGGGTGACTCCGCGC

Product: cobalamin B12-binding domain-containing protein

Products: succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MPARVLVAKPGLDGHDRGAKIVARALRDAGFEVVFTGIRQRVEDIVTIALQEDVAVVGLSILSGAHIALTTRTIEALRAA
DAGDIAVVVGGTIPPADVPRLLEVGAAGVFPTGTPLEQLVTEVRALTSTPTAP

Sequences:

>Translated_133_residues
MPARVLVAKPGLDGHDRGAKIVARALRDAGFEVVFTGIRQRVEDIVTIALQEDVAVVGLSILSGAHIALTTRTIEALRAA
DAGDIAVVVGGTIPPADVPRLLEVGAAGVFPTGTPLEQLVTEVRALTSTPTAP
>Mature_132_residues
PARVLVAKPGLDGHDRGAKIVARALRDAGFEVVFTGIRQRVEDIVTIALQEDVAVVGLSILSGAHIALTTRTIEALRAAD
AGDIAVVVGGTIPPADVPRLLEVGAAGVFPTGTPLEQLVTEVRALTSTPTAP

Specific function: Unknown

COG id: COG2185

COG function: function code I; Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

Organism=Homo sapiens, GI156105689, Length=111, Percent_Identity=43.2432432432432, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789284, Length=125, Percent_Identity=44, Blast_Score=100, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25144500, Length=134, Percent_Identity=39.5522388059701, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006159
- InterPro:   IPR016176
- InterPro:   IPR014348
- InterPro:   IPR006158
- InterPro:   IPR006099
- InterPro:   IPR006098 [H]

Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]

EC number: NA

Molecular weight: Translated: 13678; Mature: 13547

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARVLVAKPGLDGHDRGAKIVARALRDAGFEVVFTGIRQRVEDIVTIALQEDVAVVGLS
CCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILSGAHIALTTRTIEALRAADAGDIAVVVGGTIPPADVPRLLEVGAAGVFPTGTPLEQLV
HHCCCEEEEHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHH
TEVRALTSTPTAP
HHHHHHCCCCCCC
>Mature Secondary Structure 
PARVLVAKPGLDGHDRGAKIVARALRDAGFEVVFTGIRQRVEDIVTIALQEDVAVVGLS
CCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILSGAHIALTTRTIEALRAADAGDIAVVVGGTIPPADVPRLLEVGAAGVFPTGTPLEQLV
HHCCCEEEEHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHH
TEVRALTSTPTAP
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Co [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-methylmalonyl-CoA [C]

Specific reaction: L-methylmalonyl-CoA = succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1355087; 9278503 [H]