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The map label for this gene is cysQ [H]

Identifier: 158316006

GI number: 158316006

Start: 5030483

End: 5031196

Strand: Reverse

Name: cysQ [H]

Synonym: Franean1_4224

Alternate gene names: 158316006

Gene position: 5031196-5030483 (Counterclockwise)

Preceding gene: 158316007

Following gene: 158316005

Centisome position: 56.01

GC content: 74.65

Gene sequence:

>714_bases
ATGGACGATCACGCACTCGCCGCGGCCCTCGCCGAGCAGGCGGGGTCCCTCCTCCTCGATATCCGCGGGCAGGGTGGGGC
CCAGGGGGATCGGCAGTCCAACGAGCTGCTGCTGCGCCTGCTCGCGCAGACACGTCCGGGCGACGCCGTTCTGTCCGAGG
AAAGCGCCGACGATCCCGTCCGCCTCACCCGGGGCCGGGTCTGGATCATCGACCCGCTCGACGGGACCCGCGAGTACGGC
GAGCCGCCGCGAGACGACTGGGCCGTCCACGTCGCCCTCGCCGTCAACGGGACACCCACCGCGGGGGCGGTCGGACTGCC
CGCCGCCGGCCTCGTGCTGCACACCGGCGAACCACCGGCCCTCGCCGCCCCGACCTCCGGCCCGATCCGTCTCGCCGTCT
CGCGCACCCGCCCACCCGCCTGCGTCGACCAGCTTGTCGCCCGCCTGGACGCGGCCCTGGTCCCCATGGGTTCCGCCGGC
GCCAAGGCGATGGCGGTCGTCCGCGGCGACGTCGACGTCTACGCCCACTCCGGCGGCCAGTACGAATGGGACTCCGCCGC
CCCCGTCGCCGTCGCCCACGCCGCGGGCCTGCACACCTCCCGCCTCGACGGCGGACCCCTCCGCTACAACGAGCCCAACC
CCTACCTCCCCGACCTGCTCATCTGCCGCCCGGAGCTCGCCGACACCGTCCTGCGAGCACTCCATGACGCCTGA

Upstream 100 bases:

>100_bases
CCGCGGCCGCCGCCGACCTGGTCGTCGACCACCTGCGTCAGGCCGGTGTGCTCGCCCCGCCCGCGCCTCGCCCGACCCCG
CCCGCCGGAGCATGAACAGC

Downstream 100 bases:

>100_bases
CCGGGCCCCCGCAGCTGTCGGTGGCGCGAGGTGGTCTCCTGTATGACGGCCAGCTTCGTGAGCGGCGGTTCCACTGGATC
GTCGACTGCGCCGGCCCGCC

Product: inositol monophosphatase

Products: NA

Alternate protein names: PAP phosphatase; 3'(2'),5'-bisphosphate nucleotidase; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; D-fructose-1,6-bisphosphate 1-phosphohydrolase; DPNPase; Fructose-1,6-bisphosphatase; FBPase; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MDDHALAAALAEQAGSLLLDIRGQGGAQGDRQSNELLLRLLAQTRPGDAVLSEESADDPVRLTRGRVWIIDPLDGTREYG
EPPRDDWAVHVALAVNGTPTAGAVGLPAAGLVLHTGEPPALAAPTSGPIRLAVSRTRPPACVDQLVARLDAALVPMGSAG
AKAMAVVRGDVDVYAHSGGQYEWDSAAPVAVAHAAGLHTSRLDGGPLRYNEPNPYLPDLLICRPELADTVLRALHDA

Sequences:

>Translated_237_residues
MDDHALAAALAEQAGSLLLDIRGQGGAQGDRQSNELLLRLLAQTRPGDAVLSEESADDPVRLTRGRVWIIDPLDGTREYG
EPPRDDWAVHVALAVNGTPTAGAVGLPAAGLVLHTGEPPALAAPTSGPIRLAVSRTRPPACVDQLVARLDAALVPMGSAG
AKAMAVVRGDVDVYAHSGGQYEWDSAAPVAVAHAAGLHTSRLDGGPLRYNEPNPYLPDLLICRPELADTVLRALHDA
>Mature_237_residues
MDDHALAAALAEQAGSLLLDIRGQGGAQGDRQSNELLLRLLAQTRPGDAVLSEESADDPVRLTRGRVWIIDPLDGTREYG
EPPRDDWAVHVALAVNGTPTAGAVGLPAAGLVLHTGEPPALAAPTSGPIRLAVSRTRPPACVDQLVARLDAALVPMGSAG
AKAMAVVRGDVDVYAHSGGQYEWDSAAPVAVAHAAGLHTSRLDGGPLRYNEPNPYLPDLLICRPELADTVLRALHDA

Specific function: Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can ser

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Localized On The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7; =3.1.3.11; =3.1.3.25 [H]

Molecular weight: Translated: 24704; Mature: 24704

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDHALAAALAEQAGSLLLDIRGQGGAQGDRQSNELLLRLLAQTRPGDAVLSEESADDPV
CCCHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCE
RLTRGRVWIIDPLDGTREYGEPPRDDWAVHVALAVNGTPTAGAVGLPAAGLVLHTGEPPA
EEECCEEEEEECCCCCHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCC
LAAPTSGPIRLAVSRTRPPACVDQLVARLDAALVPMGSAGAKAMAVVRGDVDVYAHSGGQ
EECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCC
YEWDSAAPVAVAHAAGLHTSRLDGGPLRYNEPNPYLPDLLICRPELADTVLRALHDA
EECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCC
>Mature Secondary Structure
MDDHALAAALAEQAGSLLLDIRGQGGAQGDRQSNELLLRLLAQTRPGDAVLSEESADDPV
CCCHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCE
RLTRGRVWIIDPLDGTREYGEPPRDDWAVHVALAVNGTPTAGAVGLPAAGLVLHTGEPPA
EEECCEEEEEECCCCCHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCC
LAAPTSGPIRLAVSRTRPPACVDQLVARLDAALVPMGSAGAKAMAVVRGDVDVYAHSGGQ
EECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCC
YEWDSAAPVAVAHAAGLHTSRLDGGPLRYNEPNPYLPDLLICRPELADTVLRALHDA
EECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]