Click here to switch to the map view.

The map label for this gene is dosT [H]

Identifier: 158315991

GI number: 158315991

Start: 5011607

End: 5013994

Strand: Reverse

Name: dosT [H]

Synonym: Franean1_4209

Alternate gene names: 158315991

Gene position: 5013994-5011607 (Counterclockwise)

Preceding gene: 158315994

Following gene: 158315987

Centisome position: 55.82

GC content: 74.29

Gene sequence:

>2388_bases
ATGATCGCAGCCGTGATGGATGGGGGCCCGGTGACGTCCGAGACAAGCCATGCCGACCCGACGACCCGGCCCTGGTCACG
CAGCGGTCCGGGCCGGGCGGCGGCCGCGGAGACGTCCGCGGCGAACCTCCTCGACAGCCTGAGCGAGGTGGTGTTCCGCA
CCGACGCGGAGGGCCGCTGGACCTACCTGAACCGGGCCTGGACCACCCTCACCGGCTACGACGTCGGCCCGAGCCTGGGC
GCCCGCTTCCTCGACTACGTCCACCCCGACGAGGTCGAGTACACGACCGCGCTGTTCATGGGCGTGGTGCACGGCGGCGC
CGACCACTGCCACCACGAGACCCGCTACCGCACCCGCCACGGTGGCTACCGGCAGGTACAGATCCGCGCGAACGTGCTGC
GCGGCCCGTCCGGTGAGGTGCTCGGCAACACCGGCACGATCCTCGACGTCACCGACTCCCGGCTCGGCGCCGAGGCGGTC
GGGGAGCATGCCACGCTGCTGGAACTGATCACCGCAGGCACCGACCCCGAAGAGCTGCTGACGGGCGTCGCCGTCTACGA
CCGCGACCTGCGGCTGCGCCGCGGCTCGCCGGTCGTCGACCGCCTGGTCGGCGCGCAGCTGCTTCCCGGGGACCCGCTCG
ACCGGCTGGTCGAGCTGCTGCACCCCGCTGACTGGCAGACACGCTCCCTCGGCGGCGACTGGGGCCTGGTCGCGCTCGCC
CTGCGTACTCGTCGGGCACAGCTCGGCGACCTCGAGCTGGCGGGCGAGCGGGGCACCGGCCGGGCGCTGCGCGCCTCGGT
GATCCCGTTCGACCAGGGCGGTGAGGAGATGGCCGCGCTCGTCCTGTCCGACATCACCGACCTGCGCCGGGCCGAGCGCC
AGCAGGCCGGGCTCGCCCGGCTCGGGCAGCGCGCGCTGGCAGATCTCGACATCCCGACCCTGCTCGCCGAGGCGGTCGGT
CTGGTCACCACCACCCTGGACGTCGCCGTCTGCGACGTGATCCGCTGCGAACCCGACGGCGACCGGGCGAGCCTGGCCGA
CGGTGCGAGCCTGGCCGACGGTCCCGAGCGCGCCGGTCTGCCCGACGGATCCGCCAACGGTTCATCCACCAGCGCCGCCG
GTGGTGCTGGCGGGCCGGGGGCCGGTGCGTCCGATCCCGGGCATCTCGCGCGCCTGACCGACCCGTCGGCGCCGACCGCG
CCCACGCAGCTCGGCACCGGCCCGATCTACCTGACCGGCACGCTGGCGGCCGAGGCGAGCTCACTCGTCCACCTCGCGCT
CGGCGTCGACGAGCCCGTCGTGGCGAACGACCTCGGAACCCGTCCACACCTGCGCAGCGGGTGGTCCGACGCCGGAGGCG
CGCAGGCGGCGCTCGCGGCCCGGATCGGCTCGGCCCGGTCACCGTTCGGCGTGCTGGCCGCGGCCAGCACACGGCCGCGC
CGCTTCACCGGGGAGGAGTCACGCTTCCTCCAGTCCGTGGCGAACATCCTCGGCGCGGCGATCGACCGGGACCGCGCCGA
GCGCCGGTCGCGGCAGCTCTACGAGGAGGCCCAGCGCGGCCGCGCGTGGCTGGCGGCCAGCGCGGAGATCACCGCCGGCG
CGCTGGTGGCCGGCCAGTCCCAGCAGGCCTTCATGCTGCTCGCCTCGCTCGCCCGCGGCGTCACCTCGGCGGACGTCGGC
GCCGTGGCACTACCCGACGAGGCGGGCAACCTGGTCGCCACCGAGGTCGACTCGGCCCCCCACCGCCACTCCGACCCGGA
AATCCTGCACAGCCTCGCGCTCGCACTCGACGCGGCCGAGAACCGTCCCGAGTTCCTGGCCGGACGTCCCGTGCACGTGG
GCGATCTCGACGCGACCGACGCCTGGAGCGGCCCGGTCGCCCTGACCGGACCCACCGACGCCCGGCCGGAACCACGCGGA
AACGGGTCCGCGGCGAAGGGACCGGACGGCCCGATGGCGGTGGCGCCGCCGATCCCGCCGGATCCGCGGCTTCGCGAGGC
GCTGGTCATCCCGCTGGTCGTCGCGGACAAGCCCCTCGGCGCGCTGGTCCTGGGTAACAGCACCGAGGGCGTCCCGTTCG
CCGGGAACGACCCCGAGCTGGCCGGAGCGTTCGCGAACGACGCCGCCCTGGCCCTCCAACTGGCCGAGGCACACCGCGAA
CGCGCCCGGTTCGCGGTCTTCGAGGACCGCGAGCGCATCGCCCGGGACCTGCACGATCTCGTCATCCAACGGCTCTTCGC
GATCGGCCTGCACCTGCAGTCGCTCACGCGGGCCGTCGGTGACGTGACCGCGGCCCGCCTGAACGCGGCCATCACCGGAC
TCGACTCCACCATCGACGACATCCGTCGCACGATCTTCAAACTCCAGCCGACACCGGTAGGCGCCTGA

Upstream 100 bases:

>100_bases
TGCTCCGGGGAGGATGTTGTTCCAGCAGCGGCGGTCACCCGCACCGCGTACGGTGTCAGTCCTAGGAAGATCGCCCGTGC
CCCCGGCCGGGGTGCGGGTG

Downstream 100 bases:

>100_bases
TCCCGTCCCGGCCTGTCGGCCCGGCTGCCTAGCCCTGTTTGCGTCCAGCGCTCTGGTGGGCCTTGAGCGCGACGGCGCCG
ACGGGATCCGTGGTGGGCTG

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MIAAVMDGGPVTSETSHADPTTRPWSRSGPGRAAAAETSAANLLDSLSEVVFRTDAEGRWTYLNRAWTTLTGYDVGPSLG
ARFLDYVHPDEVEYTTALFMGVVHGGADHCHHETRYRTRHGGYRQVQIRANVLRGPSGEVLGNTGTILDVTDSRLGAEAV
GEHATLLELITAGTDPEELLTGVAVYDRDLRLRRGSPVVDRLVGAQLLPGDPLDRLVELLHPADWQTRSLGGDWGLVALA
LRTRRAQLGDLELAGERGTGRALRASVIPFDQGGEEMAALVLSDITDLRRAERQQAGLARLGQRALADLDIPTLLAEAVG
LVTTTLDVAVCDVIRCEPDGDRASLADGASLADGPERAGLPDGSANGSSTSAAGGAGGPGAGASDPGHLARLTDPSAPTA
PTQLGTGPIYLTGTLAAEASSLVHLALGVDEPVVANDLGTRPHLRSGWSDAGGAQAALAARIGSARSPFGVLAAASTRPR
RFTGEESRFLQSVANILGAAIDRDRAERRSRQLYEEAQRGRAWLAASAEITAGALVAGQSQQAFMLLASLARGVTSADVG
AVALPDEAGNLVATEVDSAPHRHSDPEILHSLALALDAAENRPEFLAGRPVHVGDLDATDAWSGPVALTGPTDARPEPRG
NGSAAKGPDGPMAVAPPIPPDPRLREALVIPLVVADKPLGALVLGNSTEGVPFAGNDPELAGAFANDAALALQLAEAHRE
RARFAVFEDRERIARDLHDLVIQRLFAIGLHLQSLTRAVGDVTAARLNAAITGLDSTIDDIRRTIFKLQPTPVGA

Sequences:

>Translated_795_residues
MIAAVMDGGPVTSETSHADPTTRPWSRSGPGRAAAAETSAANLLDSLSEVVFRTDAEGRWTYLNRAWTTLTGYDVGPSLG
ARFLDYVHPDEVEYTTALFMGVVHGGADHCHHETRYRTRHGGYRQVQIRANVLRGPSGEVLGNTGTILDVTDSRLGAEAV
GEHATLLELITAGTDPEELLTGVAVYDRDLRLRRGSPVVDRLVGAQLLPGDPLDRLVELLHPADWQTRSLGGDWGLVALA
LRTRRAQLGDLELAGERGTGRALRASVIPFDQGGEEMAALVLSDITDLRRAERQQAGLARLGQRALADLDIPTLLAEAVG
LVTTTLDVAVCDVIRCEPDGDRASLADGASLADGPERAGLPDGSANGSSTSAAGGAGGPGAGASDPGHLARLTDPSAPTA
PTQLGTGPIYLTGTLAAEASSLVHLALGVDEPVVANDLGTRPHLRSGWSDAGGAQAALAARIGSARSPFGVLAAASTRPR
RFTGEESRFLQSVANILGAAIDRDRAERRSRQLYEEAQRGRAWLAASAEITAGALVAGQSQQAFMLLASLARGVTSADVG
AVALPDEAGNLVATEVDSAPHRHSDPEILHSLALALDAAENRPEFLAGRPVHVGDLDATDAWSGPVALTGPTDARPEPRG
NGSAAKGPDGPMAVAPPIPPDPRLREALVIPLVVADKPLGALVLGNSTEGVPFAGNDPELAGAFANDAALALQLAEAHRE
RARFAVFEDRERIARDLHDLVIQRLFAIGLHLQSLTRAVGDVTAARLNAAITGLDSTIDDIRRTIFKLQPTPVGA
>Mature_795_residues
MIAAVMDGGPVTSETSHADPTTRPWSRSGPGRAAAAETSAANLLDSLSEVVFRTDAEGRWTYLNRAWTTLTGYDVGPSLG
ARFLDYVHPDEVEYTTALFMGVVHGGADHCHHETRYRTRHGGYRQVQIRANVLRGPSGEVLGNTGTILDVTDSRLGAEAV
GEHATLLELITAGTDPEELLTGVAVYDRDLRLRRGSPVVDRLVGAQLLPGDPLDRLVELLHPADWQTRSLGGDWGLVALA
LRTRRAQLGDLELAGERGTGRALRASVIPFDQGGEEMAALVLSDITDLRRAERQQAGLARLGQRALADLDIPTLLAEAVG
LVTTTLDVAVCDVIRCEPDGDRASLADGASLADGPERAGLPDGSANGSSTSAAGGAGGPGAGASDPGHLARLTDPSAPTA
PTQLGTGPIYLTGTLAAEASSLVHLALGVDEPVVANDLGTRPHLRSGWSDAGGAQAALAARIGSARSPFGVLAAASTRPR
RFTGEESRFLQSVANILGAAIDRDRAERRSRQLYEEAQRGRAWLAASAEITAGALVAGQSQQAFMLLASLARGVTSADVG
AVALPDEAGNLVATEVDSAPHRHSDPEILHSLALALDAAENRPEFLAGRPVHVGDLDATDAWSGPVALTGPTDARPEPRG
NGSAAKGPDGPMAVAPPIPPDPRLREALVIPLVVADKPLGALVLGNSTEGVPFAGNDPELAGAFANDAALALQLAEAHRE
RARFAVFEDRERIARDLHDLVIQRLFAIGLHLQSLTRAVGDVTAARLNAAITGLDSTIDDIRRTIFKLQPTPVGA

Specific function: Interacts with the two-component regulatory system devR/devS (dosR/dosS) involved in onset of the dormancy response. May act as a direct hypoxia sensor (rather than a redox sensor); the normal state is the oxygenated form, while the deoxy form is probably

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: NA

Molecular weight: Translated: 83037; Mature: 83037

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAVMDGGPVTSETSHADPTTRPWSRSGPGRAAAAETSAANLLDSLSEVVFRTDAEGRW
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
TYLNRAWTTLTGYDVGPSLGARFLDYVHPDEVEYTTALFMGVVHGGADHCHHETRYRTRH
EEECCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
GGYRQVQIRANVLRGPSGEVLGNTGTILDVTDSRLGAEAVGEHATLLELITAGTDPEELL
CCEEEEEEEEEECCCCCCCEECCCCCEEEECCCCCCHHHHCCHHHHHHHHHCCCCHHHHH
TGVAVYDRDLRLRRGSPVVDRLVGAQLLPGDPLDRLVELLHPADWQTRSLGGDWGLVALA
HHHHHHCCCHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCHHHHHHH
LRTRRAQLGDLELAGERGTGRALRASVIPFDQGGEEMAALVLSDITDLRRAERQQAGLAR
HHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQRALADLDIPTLLAEAVGLVTTTLDVAVCDVIRCEPDGDRASLADGASLADGPERAGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCC
PDGSANGSSTSAAGGAGGPGAGASDPGHLARLTDPSAPTAPTQLGTGPIYLTGTLAAEAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEHHHHHH
SLVHLALGVDEPVVANDLGTRPHLRSGWSDAGGAQAALAARIGSARSPFGVLAAASTRPR
HHEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCC
RFTGEESRFLQSVANILGAAIDRDRAERRSRQLYEEAQRGRAWLAASAEITAGALVAGQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCC
QQAFMLLASLARGVTSADVGAVALPDEAGNLVATEVDSAPHRHSDPEILHSLALALDAAE
HHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCC
NRPEFLAGRPVHVGDLDATDAWSGPVALTGPTDARPEPRGNGSAAKGPDGPMAVAPPIPP
CCCCHHCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
DPRLREALVIPLVVADKPLGALVLGNSTEGVPFAGNDPELAGAFANDAALALQLAEAHRE
CCCCHHHEEEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHH
RARFAVFEDRERIARDLHDLVIQRLFAIGLHLQSLTRAVGDVTAARLNAAITGLDSTIDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IRRTIFKLQPTPVGA
HHHHHHCCCCCCCCC
>Mature Secondary Structure
MIAAVMDGGPVTSETSHADPTTRPWSRSGPGRAAAAETSAANLLDSLSEVVFRTDAEGRW
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
TYLNRAWTTLTGYDVGPSLGARFLDYVHPDEVEYTTALFMGVVHGGADHCHHETRYRTRH
EEECCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
GGYRQVQIRANVLRGPSGEVLGNTGTILDVTDSRLGAEAVGEHATLLELITAGTDPEELL
CCEEEEEEEEEECCCCCCCEECCCCCEEEECCCCCCHHHHCCHHHHHHHHHCCCCHHHHH
TGVAVYDRDLRLRRGSPVVDRLVGAQLLPGDPLDRLVELLHPADWQTRSLGGDWGLVALA
HHHHHHCCCHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCHHHHHHH
LRTRRAQLGDLELAGERGTGRALRASVIPFDQGGEEMAALVLSDITDLRRAERQQAGLAR
HHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQRALADLDIPTLLAEAVGLVTTTLDVAVCDVIRCEPDGDRASLADGASLADGPERAGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCC
PDGSANGSSTSAAGGAGGPGAGASDPGHLARLTDPSAPTAPTQLGTGPIYLTGTLAAEAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEHHHHHH
SLVHLALGVDEPVVANDLGTRPHLRSGWSDAGGAQAALAARIGSARSPFGVLAAASTRPR
HHEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCC
RFTGEESRFLQSVANILGAAIDRDRAERRSRQLYEEAQRGRAWLAASAEITAGALVAGQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCC
QQAFMLLASLARGVTSADVGAVALPDEAGNLVATEVDSAPHRHSDPEILHSLALALDAAE
HHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCC
NRPEFLAGRPVHVGDLDATDAWSGPVALTGPTDARPEPRGNGSAAKGPDGPMAVAPPIPP
CCCCHHCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
DPRLREALVIPLVVADKPLGALVLGNSTEGVPFAGNDPELAGAFANDAALALQLAEAHRE
CCCCHHHEEEEEEECCCCCCEEEECCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHH
RARFAVFEDRERIARDLHDLVIQRLFAIGLHLQSLTRAVGDVTAARLNAAITGLDSTIDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IRRTIFKLQPTPVGA
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]