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The map label for this gene is 158315934

Identifier: 158315934

GI number: 158315934

Start: 4932356

End: 4933591

Strand: Reverse

Name: 158315934

Synonym: Franean1_4152

Alternate gene names: NA

Gene position: 4933591-4932356 (Counterclockwise)

Preceding gene: 158315935

Following gene: 158315932

Centisome position: 54.93

GC content: 68.69

Gene sequence:

>1236_bases
ATGACCCCCCTGCATGCCTTCCCCCTGGAGCCCGCCCCGATCCATGTGTCCGACGACGTCCTCGATGACCTGCGCGCCCG
TCTCACCCTGACCCGTCCGCCGCTGGACGAGGGGAATGAGGACTGGTCCTACGGCGTCCCGGGCAGCTATCTGCGTGAGC
TGGTCGTCTACTGGCGGGACGGCTACGACTGGCGCAAGGCCGAGGCCGCCATCAACGCCTACGAGCACTACCAGGTGAGC
GTCGCCGGTGTCCCGGTGCACTTCATGCGCAGGCCCGGCCGCGGCCCCCGCCCGATTCCGTTGATCCTCACCCACGGCTG
GCCGTGGACGTTCTGGCACTGGTCGAAGGTGATCGACCCGCTCGCCGACCCGGCCACGTTCGGCGGTGACCCCACCGACG
CGTTCGACGTCCTCGTGCCGTCCCTGCCCGGCTTCGGTTTCCCTGGCCCGCTCACCAGCTTTTCCGACGTCAACTTCTGG
AAGGTCTCCGACCTCTGGCACACCCTGATGACCGAGACCCTGGGATACGAGAAGTACGCCGCCGGGGGCTGCGACATCGG
CGGGATCGTCTCCAGCCAGCTCGGCCACAAGTACGCCGACGAGCTGTACGGCATCCACATCGGCTCCGGGCTGCCGCTCG
ACTTCTTCACCGGTCCCCGCGCCTGGGACTTCGCCCGGAACCGGCCCCTCACCGACGACCAGCCCGCCGACGTCCGCGCC
CGGATCATCGAGCTGGACCACCGCTCGGCGTCCCACCTCGCCGTGCACATGCTCGACGGCGCCACCCTGGCCCACGGGCT
GAGCGACTCACCCGCCGGACTGCTCGCCTGGCTGCTGGAACGCTGGAACGCCTGGAGCGACAACGGCGGCGACGTCGAGT
CCGTCTTCACCAAGGACGACCTGCTCACCCACGCCACGATCTACTGGGTGAACAACTCCATCGCCACGTCGATGCGTTAC
TACACCAACGCCAACCGCTACCCCTGGGCTCCTGCCCACGACCGCACCCCGGTCGTGCAGGCCCCGGTCGGCCTCACCTT
CGTCACCTACGAGAACCCGCCCGGCATCCACACCGCAGACGAGCGTGTCCAGGCGTTCAAGACCGGCCCGCAGGCCGACT
GGTTCAACCACGTCAACGTCAACGCCCACGACCACGGCGGCCACTTCATCCCCTGGGAGAATCCCGACGCCTGGGTGAGC
GACCTGCGACGCACCTTCCACGGCCGCAGGCCCTGA

Upstream 100 bases:

>100_bases
AACGGCCCGGCGAGCATCTCCAAAGCGATGCCGTGCGCGGTGAGGTGGTCGGCGAGCGCGGTCAGTTCGACAGAGTCGCG
TCCGATAGGAGAATCACGCC

Downstream 100 bases:

>100_bases
AGGCTCGTCTTCAGACAGGTAGCGGGCGGCGTAGATCGTGCGTCGGAGAGCCCCGTATTCCTTGAGCGCCGCGGCCAGGG
CGTTCTGCCGGCCGGAGGCT

Product: epocide hydrolase domain-containing protein

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTPLHAFPLEPAPIHVSDDVLDDLRARLTLTRPPLDEGNEDWSYGVPGSYLRELVVYWRDGYDWRKAEAAINAYEHYQVS
VAGVPVHFMRRPGRGPRPIPLILTHGWPWTFWHWSKVIDPLADPATFGGDPTDAFDVLVPSLPGFGFPGPLTSFSDVNFW
KVSDLWHTLMTETLGYEKYAAGGCDIGGIVSSQLGHKYADELYGIHIGSGLPLDFFTGPRAWDFARNRPLTDDQPADVRA
RIIELDHRSASHLAVHMLDGATLAHGLSDSPAGLLAWLLERWNAWSDNGGDVESVFTKDDLLTHATIYWVNNSIATSMRY
YTNANRYPWAPAHDRTPVVQAPVGLTFVTYENPPGIHTADERVQAFKTGPQADWFNHVNVNAHDHGGHFIPWENPDAWVS
DLRRTFHGRRP

Sequences:

>Translated_411_residues
MTPLHAFPLEPAPIHVSDDVLDDLRARLTLTRPPLDEGNEDWSYGVPGSYLRELVVYWRDGYDWRKAEAAINAYEHYQVS
VAGVPVHFMRRPGRGPRPIPLILTHGWPWTFWHWSKVIDPLADPATFGGDPTDAFDVLVPSLPGFGFPGPLTSFSDVNFW
KVSDLWHTLMTETLGYEKYAAGGCDIGGIVSSQLGHKYADELYGIHIGSGLPLDFFTGPRAWDFARNRPLTDDQPADVRA
RIIELDHRSASHLAVHMLDGATLAHGLSDSPAGLLAWLLERWNAWSDNGGDVESVFTKDDLLTHATIYWVNNSIATSMRY
YTNANRYPWAPAHDRTPVVQAPVGLTFVTYENPPGIHTADERVQAFKTGPQADWFNHVNVNAHDHGGHFIPWENPDAWVS
DLRRTFHGRRP
>Mature_410_residues
TPLHAFPLEPAPIHVSDDVLDDLRARLTLTRPPLDEGNEDWSYGVPGSYLRELVVYWRDGYDWRKAEAAINAYEHYQVSV
AGVPVHFMRRPGRGPRPIPLILTHGWPWTFWHWSKVIDPLADPATFGGDPTDAFDVLVPSLPGFGFPGPLTSFSDVNFWK
VSDLWHTLMTETLGYEKYAAGGCDIGGIVSSQLGHKYADELYGIHIGSGLPLDFFTGPRAWDFARNRPLTDDQPADVRAR
IIELDHRSASHLAVHMLDGATLAHGLSDSPAGLLAWLLERWNAWSDNGGDVESVFTKDDLLTHATIYWVNNSIATSMRYY
TNANRYPWAPAHDRTPVVQAPVGLTFVTYENPPGIHTADERVQAFKTGPQADWFNHVNVNAHDHGGHFIPWENPDAWVSD
LRRTFHGRRP

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=414, Percent_Identity=27.7777777777778, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI209862837, Length=414, Percent_Identity=27.7777777777778, Blast_Score=182, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17564944, Length=341, Percent_Identity=29.9120234604106, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193207462, Length=350, Percent_Identity=22, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24655327, Length=420, Percent_Identity=28.0952380952381, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI20130139, Length=413, Percent_Identity=26.1501210653753, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI19922580, Length=353, Percent_Identity=26.628895184136, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 46154; Mature: 46023

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLHAFPLEPAPIHVSDDVLDDLRARLTLTRPPLDEGNEDWSYGVPGSYLRELVVYWRD
CCCCCCCCCCCCCEECCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
GYDWRKAEAAINAYEHYQVSVAGVPVHFMRRPGRGPRPIPLILTHGWPWTFWHWSKVIDP
CCCHHHHHHHHHHHHEEEEEEECCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
LADPATFGGDPTDAFDVLVPSLPGFGFPGPLTSFSDVNFWKVSDLWHTLMTETLGYEKYA
HCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCHHHC
AGGCDIGGIVSSQLGHKYADELYGIHIGSGLPLDFFTGPRAWDFARNRPLTDDQPADVRA
CCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHCCCCCCHHHHCCCCCCCCCCCCCEE
RIIELDHRSASHLAVHMLDGATLAHGLSDSPAGLLAWLLERWNAWSDNGGDVESVFTKDD
EEEEECCCCCCEEEEEEECCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LLTHATIYWVNNSIATSMRYYTNANRYPWAPAHDRTPVVQAPVGLTFVTYENPPGIHTAD
HHEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCHH
ERVQAFKTGPQADWFNHVNVNAHDHGGHFIPWENPDAWVSDLRRTFHGRRP
HHHHHHHCCCCCCCCCEEECCEECCCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TPLHAFPLEPAPIHVSDDVLDDLRARLTLTRPPLDEGNEDWSYGVPGSYLRELVVYWRD
CCCCCCCCCCCCEECCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
GYDWRKAEAAINAYEHYQVSVAGVPVHFMRRPGRGPRPIPLILTHGWPWTFWHWSKVIDP
CCCHHHHHHHHHHHHEEEEEEECCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
LADPATFGGDPTDAFDVLVPSLPGFGFPGPLTSFSDVNFWKVSDLWHTLMTETLGYEKYA
HCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCHHHC
AGGCDIGGIVSSQLGHKYADELYGIHIGSGLPLDFFTGPRAWDFARNRPLTDDQPADVRA
CCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHCCCCCCHHHHCCCCCCCCCCCCCEE
RIIELDHRSASHLAVHMLDGATLAHGLSDSPAGLLAWLLERWNAWSDNGGDVESVFTKDD
EEEEECCCCCCEEEEEEECCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LLTHATIYWVNNSIATSMRYYTNANRYPWAPAHDRTPVVQAPVGLTFVTYENPPGIHTAD
HHEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCHH
ERVQAFKTGPQADWFNHVNVNAHDHGGHFIPWENPDAWVSDLRRTFHGRRP
HHHHHHHCCCCCCCCCEEECCEECCCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]