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The map label for this gene is paaK [H]

Identifier: 158315410

GI number: 158315410

Start: 4282696

End: 4284006

Strand: Reverse

Name: paaK [H]

Synonym: Franean1_3613

Alternate gene names: 158315410

Gene position: 4284006-4282696 (Counterclockwise)

Preceding gene: 158315417

Following gene: 158315409

Centisome position: 47.7

GC content: 72.77

Gene sequence:

>1311_bases
ATGCCGTGGACGCGTCCTGACCCAAACAGCTGGTCCAGCCCGGACGAACTTGGCGCCCTGCAGCGCGCCGAACTGCCCCG
AGTCCTGGCGACCGCGCTGCGCTCGCCTTTCTACGCGGCCCGGTACGCCGGCGGCGATCCGCCGCGGACCGCAGCCGACT
TCGCGGGCCTCCCCCTCACCACCAAGCAGGACCTGCGCGACGCCTACCCGTTCGGCATGCTCGCCGTTCCGCGTGCGGAG
CTCGCGACCTACCACGAGTCGAGCGGCACGGCCGGCGACCCGACCGCGTCCTACTACACCGAGAAGGACTGGGTCGACCT
GGCGGAACGGTTCGCCCGCAAGTGGATCGGCATCAGCCCGTCGGACACCCTGCTGGTCCGCACCCCGTACGCGCTGGTCA
TCACCGGCCATCTCGCGCACGCCGCGGGCCGGCTGTGCGGCGCCACGGTCGTCCCGGGCGACCTGCGGTCGCTGGCCACC
CCGTTGTCGCGCATCGTGCGGGTGCTGCACGACCTGGAGGTCACCCTCACCTGGTGCAACCCGACCGAGGCGGTGATGCT
CGCCGCCGCCGCCCGGGCCGCGGGGCTGCGCCCGGAACGGGACTTCCCCGCGCTGCGCGCGATGTTCGTCGCCGCCGAGC
CGCTCACAGACGTCCGCAGGCACCGCATCAGCGAGATCTGGGGCGGCGTCCCGGTGATCGAGGAGTACGGCTCGACCGAG
ACCGGCACGATAGCCGGCCAGTGCCCGTCGGGCGCGATGCACCTGTGGGCCGACCGGGCAATCTTCGAGGTCTGGTCGCC
GGAGACGGGGACGCTCGGCCCGACTGGGCGCGGCCAGCTCGTGGTGACGCCGCTGTTCCGCGAGGCCATGCCGCTGCTGC
GGTACAACCTCGCCGACGAGGTAGAGGTCTCCGACGCGCCCTGTGTGTGCGGCTGGCAGCTGCCGACGGTGCGGGTGTTC
GGCCGGGCGGCGTTCGCGTACCCCGTCGGCTCCGCCGCCGTCACCCAGCAGCAGCTCGAGGAGCTCGTCTTCAGGCTTCC
CGCGGCCTGCGACGTGGTCTTCTGGCGCGCGGTCGCCGAACCGGCGGTGCTGCGGGTGGAGATCGAGGTCGCTGACGAGG
CCCGCGAACGCGCGGTCAAGGAGCTGCGCGCGGCCATCGACCGGGAACTCGGCGTCCCGCACCAGGTCACCGGCCTGTCT
CCGGGCACGATCGTCCCGGCCGAGGCGCTGCGGGCGCAGCGGGACATCCTCAAGGCCCGCTACCTGTTCGGGCCGGGCGA
GGACTGGAACAAGGCGGTCATGTACCAGTGA

Upstream 100 bases:

>100_bases
TGGCTACTCACGATCCGGCGCACGTACCGGTGCTGTGCTGGACGTCGCCGGTCCACCTGACACGCACGCCGCAACGAACC
TCACCCGAACGGGAGTCCCG

Downstream 100 bases:

>100_bases
CCGCCGCCGACACACCCCCTCCGGTCCGCCCCGCCGGCACACTGCCGACGCTCGTCGTCGGTGGCGGCATCGGCGGGCTG
TCCGCTGCCCTCGCCGTGGC

Product: coenzyme F390 synthetase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MPWTRPDPNSWSSPDELGALQRAELPRVLATALRSPFYAARYAGGDPPRTAADFAGLPLTTKQDLRDAYPFGMLAVPRAE
LATYHESSGTAGDPTASYYTEKDWVDLAERFARKWIGISPSDTLLVRTPYALVITGHLAHAAGRLCGATVVPGDLRSLAT
PLSRIVRVLHDLEVTLTWCNPTEAVMLAAAARAAGLRPERDFPALRAMFVAAEPLTDVRRHRISEIWGGVPVIEEYGSTE
TGTIAGQCPSGAMHLWADRAIFEVWSPETGTLGPTGRGQLVVTPLFREAMPLLRYNLADEVEVSDAPCVCGWQLPTVRVF
GRAAFAYPVGSAAVTQQQLEELVFRLPAACDVVFWRAVAEPAVLRVEIEVADEARERAVKELRAAIDRELGVPHQVTGLS
PGTIVPAEALRAQRDILKARYLFGPGEDWNKAVMYQ

Sequences:

>Translated_436_residues
MPWTRPDPNSWSSPDELGALQRAELPRVLATALRSPFYAARYAGGDPPRTAADFAGLPLTTKQDLRDAYPFGMLAVPRAE
LATYHESSGTAGDPTASYYTEKDWVDLAERFARKWIGISPSDTLLVRTPYALVITGHLAHAAGRLCGATVVPGDLRSLAT
PLSRIVRVLHDLEVTLTWCNPTEAVMLAAAARAAGLRPERDFPALRAMFVAAEPLTDVRRHRISEIWGGVPVIEEYGSTE
TGTIAGQCPSGAMHLWADRAIFEVWSPETGTLGPTGRGQLVVTPLFREAMPLLRYNLADEVEVSDAPCVCGWQLPTVRVF
GRAAFAYPVGSAAVTQQQLEELVFRLPAACDVVFWRAVAEPAVLRVEIEVADEARERAVKELRAAIDRELGVPHQVTGLS
PGTIVPAEALRAQRDILKARYLFGPGEDWNKAVMYQ
>Mature_435_residues
PWTRPDPNSWSSPDELGALQRAELPRVLATALRSPFYAARYAGGDPPRTAADFAGLPLTTKQDLRDAYPFGMLAVPRAEL
ATYHESSGTAGDPTASYYTEKDWVDLAERFARKWIGISPSDTLLVRTPYALVITGHLAHAAGRLCGATVVPGDLRSLATP
LSRIVRVLHDLEVTLTWCNPTEAVMLAAAARAAGLRPERDFPALRAMFVAAEPLTDVRRHRISEIWGGVPVIEEYGSTET
GTIAGQCPSGAMHLWADRAIFEVWSPETGTLGPTGRGQLVVTPLFREAMPLLRYNLADEVEVSDAPCVCGWQLPTVRVFG
RAAFAYPVGSAAVTQQQLEELVFRLPAACDVVFWRAVAEPAVLRVEIEVADEARERAVKELRAAIDRELGVPHQVTGLSP
GTIVPAEALRAQRDILKARYLFGPGEDWNKAVMYQ

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=434, Percent_Identity=29.4930875576037, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47603; Mature: 47472

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWTRPDPNSWSSPDELGALQRAELPRVLATALRSPFYAARYAGGDPPRTAADFAGLPLT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHCCCCCC
TKQDLRDAYPFGMLAVPRAELATYHESSGTAGDPTASYYTEKDWVDLAERFARKWIGISP
CHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
SDTLLVRTPYALVITGHLAHAAGRLCGATVVPGDLRSLATPLSRIVRVLHDLEVTLTWCN
CCEEEEECCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECC
PTEAVMLAAAARAAGLRPERDFPALRAMFVAAEPLTDVRRHRISEIWGGVPVIEEYGSTE
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHCCCCC
TGTIAGQCPSGAMHLWADRAIFEVWSPETGTLGPTGRGQLVVTPLFREAMPLLRYNLADE
CCEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCC
VEVSDAPCVCGWQLPTVRVFGRAAFAYPVGSAAVTQQQLEELVFRLPAACDVVFWRAVAE
CCCCCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
PAVLRVEIEVADEARERAVKELRAAIDRELGVPHQVTGLSPGTIVPAEALRAQRDILKAR
CEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHH
YLFGPGEDWNKAVMYQ
HHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PWTRPDPNSWSSPDELGALQRAELPRVLATALRSPFYAARYAGGDPPRTAADFAGLPLT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHCCCCCC
TKQDLRDAYPFGMLAVPRAELATYHESSGTAGDPTASYYTEKDWVDLAERFARKWIGISP
CHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
SDTLLVRTPYALVITGHLAHAAGRLCGATVVPGDLRSLATPLSRIVRVLHDLEVTLTWCN
CCEEEEECCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECC
PTEAVMLAAAARAAGLRPERDFPALRAMFVAAEPLTDVRRHRISEIWGGVPVIEEYGSTE
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHCCCCC
TGTIAGQCPSGAMHLWADRAIFEVWSPETGTLGPTGRGQLVVTPLFREAMPLLRYNLADE
CCEEECCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCCC
VEVSDAPCVCGWQLPTVRVFGRAAFAYPVGSAAVTQQQLEELVFRLPAACDVVFWRAVAE
CCCCCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
PAVLRVEIEVADEARERAVKELRAAIDRELGVPHQVTGLSPGTIVPAEALRAQRDILKAR
CEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHH
YLFGPGEDWNKAVMYQ
HHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]