BacMap

Definition	Frankia sp. EAN1pec chromosome, complete genome.
Accession	NC_009921
Length	8,982,042

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The map label for this gene is fabG [H]

Identifier: 158315183

GI number: 158315183

Start: 4008397

End: 4009269

Strand: Direct

Name: fabG [H]

Synonym: Franean1_3383

Alternate gene names: 158315183

Gene position: 4008397-4009269 (Clockwise)

Preceding gene: 158315181

Following gene: 158315184

Centisome position: 44.63

GC content: 64.6

Gene sequence:

>873_bases
ATGGATTCGGATACGCAGTACCTGACTCAGGCGCTGGGGCTGGACCGGCTGCCCACCCATATCATCGACAAGCGGGTAAG
CGAGCTGCTGGACCTGAGCGGCCAGAAGGCGATTGTCATCGGTGCGGGGGGTGACGGATTAGGTCATGCGATCGCCAATC
GGCTGGCTGGTTCCGGTGCCGATATCGCGCTGGTCGGCCGGACCTTCGAGAAGGTCGAGCGGCGCGCAGGGGAGATCGCG
AAGCGCTGGGGCGTGAAGACCGTTCCGATCCGCGCCGACATGTCGGACTGGGACCAGGTCCATCGGGCGGTGCGGGAGAG
CCGGGAGGCGCTCGGCGGCCTGGACATCATGGTGAACAACCCGGTCATGGTGGCCGCCGGGGCCTTCGAGAAGCACACGA
AGGAAGAGATCGACCGGACCGTCCTGGGTAGCCTGACCATGATGATGTACGGCGCCCACGCGGCGCTGGAGTACCTGCTG
CCCCAGGGCTCAGGGAAGATCATCAACATCGGGGCGGTGGGTGGGCGAATTCAGCAGCCCGGCCTGACGGTCTACTGCTC
GTGCAAGGCTGGGGTCATCGGTTTCACCCGTAATCTCGCGCACGAGGTCGCGTCCCGTGGCGTCAACGTGCTTGGTGTGG
CTCCGGGTATCATGATCAAGTCTGAGATGAAGGCGATGCTCTTCGAGCCGCAGAACGAGGCGCAGTTCGCGGGTCGGAAG
TCCATCATCGATGCGCTGAAGAACCAGGTGCAGCTGGGCCGGGTCTGCCTGCCGGAAGAGGTCGCCAACATGGTCGCGTA
CCTCTGCTCGGAGGCCGCCGACTACATGTGCGGTCAGACCATCGACGTCGCGGGCGGTCAGTGGATGGGATGA

Upstream 100 bases:

>100_bases
GCTCCGGCGGCATGGCCGTAACATCCTTGGAACCAGGCGAGATGGTGCGTCTTGCTGTGCTGGATAAAACTTTTTCTTTG
GGCCGGCGATAGGGGATCTC

Downstream 100 bases:

>100_bases
TCTGATCGCTGGGAGATTGGATGGGATGTGCTGTCGTCGCGCCAGGGGCGCGGCCGATGATCCTGGCGCGACGACACGCG
GGGGAATGGTTTTTCAGTAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MDSDTQYLTQALGLDRLPTHIIDKRVSELLDLSGQKAIVIGAGGDGLGHAIANRLAGSGADIALVGRTFEKVERRAGEIA
KRWGVKTVPIRADMSDWDQVHRAVRESREALGGLDIMVNNPVMVAAGAFEKHTKEEIDRTVLGSLTMMMYGAHAALEYLL
PQGSGKIINIGAVGGRIQQPGLTVYCSCKAGVIGFTRNLAHEVASRGVNVLGVAPGIMIKSEMKAMLFEPQNEAQFAGRK
SIIDALKNQVQLGRVCLPEEVANMVAYLCSEAADYMCGQTIDVAGGQWMG

Sequences:

>Translated_290_residues
MDSDTQYLTQALGLDRLPTHIIDKRVSELLDLSGQKAIVIGAGGDGLGHAIANRLAGSGADIALVGRTFEKVERRAGEIA
KRWGVKTVPIRADMSDWDQVHRAVRESREALGGLDIMVNNPVMVAAGAFEKHTKEEIDRTVLGSLTMMMYGAHAALEYLL
PQGSGKIINIGAVGGRIQQPGLTVYCSCKAGVIGFTRNLAHEVASRGVNVLGVAPGIMIKSEMKAMLFEPQNEAQFAGRK
SIIDALKNQVQLGRVCLPEEVANMVAYLCSEAADYMCGQTIDVAGGQWMG
>Mature_290_residues
MDSDTQYLTQALGLDRLPTHIIDKRVSELLDLSGQKAIVIGAGGDGLGHAIANRLAGSGADIALVGRTFEKVERRAGEIA
KRWGVKTVPIRADMSDWDQVHRAVRESREALGGLDIMVNNPVMVAAGAFEKHTKEEIDRTVLGSLTMMMYGAHAALEYLL
PQGSGKIINIGAVGGRIQQPGLTVYCSCKAGVIGFTRNLAHEVASRGVNVLGVAPGIMIKSEMKAMLFEPQNEAQFAGRK
SIIDALKNQVQLGRVCLPEEVANMVAYLCSEAADYMCGQTIDVAGGQWMG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=27.2373540856031, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=28.7878787878788, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=30.4511278195489, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7705925, Length=260, Percent_Identity=26.1538461538462, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=27.4900398406374, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI31542939, Length=253, Percent_Identity=29.2490118577075, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI5031737, Length=261, Percent_Identity=27.9693486590038, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=25.8687258687259, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI224922801, Length=187, Percent_Identity=31.0160427807487, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI10190704, Length=266, Percent_Identity=27.8195488721804, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4557649, Length=188, Percent_Identity=28.7234042553192, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226371731, Length=213, Percent_Identity=29.1079812206573, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4503817, Length=242, Percent_Identity=24.3801652892562, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=31.9230769230769, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=27.027027027027, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789378, Length=304, Percent_Identity=28.2894736842105, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789208, Length=266, Percent_Identity=28.1954887218045, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI2367175, Length=259, Percent_Identity=31.2741312741313, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=25.2873563218391, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=28.2945736434109, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=25.0965250965251, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367365, Length=260, Percent_Identity=29.2307692307692, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=25.3012048192771, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=25.3846153846154, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=23.3716475095785, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=26.5873015873016, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=290, Percent_Identity=28.2758620689655, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=263, Percent_Identity=30.7984790874525, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=29.6153846153846, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=253, Percent_Identity=25.296442687747, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=274, Percent_Identity=27.7372262773723, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=247, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=26.8774703557312, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=26.3779527559055, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=26.5682656826568, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=28.6764705882353, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=25.6704980842912, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=274, Percent_Identity=26.2773722627737, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=24.8995983935743, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=26.865671641791, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=25.3787878787879, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=274, Percent_Identity=27.007299270073, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=28.2527881040892, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=26.3358778625954, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=24.7191011235955, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=25.3731343283582, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=25.187969924812, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=202, Percent_Identity=25.7425742574257, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=175, Percent_Identity=26.2857142857143, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=24.1509433962264, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=25.968992248062, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=27.0916334661355, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=173, Percent_Identity=26.0115606936416, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=259, Percent_Identity=22.7799227799228, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=270, Percent_Identity=25.1851851851852, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=237, Percent_Identity=27.0042194092827, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=28.6821705426357, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=29.3650793650794, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=28.6821705426357, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24640442, Length=217, Percent_Identity=30.8755760368664, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=25.968992248062, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=28.957528957529, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24584744, Length=266, Percent_Identity=27.4436090225564, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574402, Length=266, Percent_Identity=27.4436090225564, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644337, Length=271, Percent_Identity=29.8892988929889, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161076933, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584748, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737361, Length=203, Percent_Identity=28.0788177339901, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 31049; Mature: 31049

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSDTQYLTQALGLDRLPTHIIDKRVSELLDLSGQKAIVIGAGGDGLGHAIANRLAGSGA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCC
DIALVGRTFEKVERRAGEIAKRWGVKTVPIRADMSDWDQVHRAVRESREALGGLDIMVNN
CEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEECC
PVMVAAGAFEKHTKEEIDRTVLGSLTMMMYGAHAALEYLLPQGSGKIINIGAVGGRIQQP
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEECCC
GLTVYCSCKAGVIGFTRNLAHEVASRGVNVLGVAPGIMIKSEMKAMLFEPQNEAQFAGRK
CEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHH
SIIDALKNQVQLGRVCLPEEVANMVAYLCSEAADYMCGQTIDVAGGQWMG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
>Mature Secondary Structure
MDSDTQYLTQALGLDRLPTHIIDKRVSELLDLSGQKAIVIGAGGDGLGHAIANRLAGSGA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCC
DIALVGRTFEKVERRAGEIAKRWGVKTVPIRADMSDWDQVHRAVRESREALGGLDIMVNN
CEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEECC
PVMVAAGAFEKHTKEEIDRTVLGSLTMMMYGAHAALEYLLPQGSGKIINIGAVGGRIQQP
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEECCC
GLTVYCSCKAGVIGFTRNLAHEVASRGVNVLGVAPGIMIKSEMKAMLFEPQNEAQFAGRK
CEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHH
SIIDALKNQVQLGRVCLPEEVANMVAYLCSEAADYMCGQTIDVAGGQWMG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]