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The map label for this gene is yrkH [H]

Identifier: 158315161

GI number: 158315161

Start: 3984977

End: 3986377

Strand: Direct

Name: yrkH [H]

Synonym: Franean1_3361

Alternate gene names: 158315161

Gene position: 3984977-3986377 (Clockwise)

Preceding gene: 158315160

Following gene: 158315162

Centisome position: 44.37

GC content: 73.59

Gene sequence:

>1401_bases
ATGACGATTGCCGTTGAGGTCGTGGAGACCTCCACGCTCGGCGACCGCAGCTACCTGGCGCACGACGGCCAGCTGGCGGT
GGTGGTCGACCCGCAGCGTGACATCGACCGGATCCTGGCCCTGGCCGGCGGGATCGGCGTGCGGATCAGTCACGTGGTGG
AGACCCATCTGCACAACGACTACGTCTCGGGCGGGCTCGCGCTGGCCCGGGTGACCGGCGCCCGCTACGGGGTGGCGGCG
GCCGACGACGTCCACTTCGACCGTCTGCCGTTGTCCGACGGCGACGAGATCACGATCTCCGACGAGGCCGCGATGACGGT
GGTGGCCACCCCCGGCCACACCTTTCATCACCTGTCGTTCCTGCTCCACGGCCCGAAGGGCCCGGCCGGGGTGTTCACTG
GCGGGTCGCTGCTGTTTGGTACCACCGGCCGCACCGACCTGCTGGGCGCCCAGCACGCGCACACCCTTGCCCGGCACCAG
CACGCGTCGGCGCGGCGGCTGGCCGACCTGCTGCCGCAGGGGGCGCAGGTCTGGCCGACGCACGGCTTCGGCAGCTTCTG
CTCGGCCAGCCAGTCCGACGTTCCCGCGTCGACCATCGGACAGGAACGGACGATCAATCCGGTGCTGCGGCTGGCGGCGG
ACGACTTCGTCACCGAGGTCCTCGCCGGCCTGGACGCGTTCCCCGCCTACTACGCCCACATGGGCGCGCGGAACGCCGGC
GGGGCCGACCTGGTGGATCTCACCCCGGTCAGGGTCGCCGACGCGGGCGAGCTGCGCTCCCGGATCACGGCCGGCGAGTG
GGTGGTCGACCTGCGGTCCCGGAAGGCCTTTGCGCACCGGCACCTGACCGGGACGCTGAGCCTCGGCCTGGACGGTCCGA
TGTCGACCTGGCTCGGCTGGCTGATGAGCTGGGGGATGCCGGTGACGCTGCTCGGCGAGTCCGACGCCCAGATCGGCCAG
GCACAGCGGGAGCTGGCCCGCATCGGCATCGACCGCCCGGCGGCCGCCGCGACCGGCACCCCCGAGCAGTGGGCCGCGGG
CGACCAGTCGCGCCTGGGCCCGCTGCCTTCGGCGACGTACCCGGAGCTGGCCGCGGCGCTGGCCGGACGTCCGCCGCGTG
GCCTGCCCGCTCCCGATGTCGTGCTGGACGTCCGGCTGCGCAACGAGTGGCGGAACGGACACCTTGCCGGGGCCGTGCAC
ATCCCGCTGCCCGAGCTGCCCGGCCGGCTCGGGGAGGTGCCGGGCGAAGCCGTGTGGGTGTACTGCGGGTCCGGGTACCG
CGCCGCTGCCGCCGCCAGCCTCCTTGCCCGCGCCGGCCGCACCGCGGCGTTCATCGACGACTCCTACACCGCTGCCGCCG
ACGCCGGCCTGCCGATCGTCTCCGGGGAGGGAGCGGAATGA

Upstream 100 bases:

>100_bases
CCATCCCTCGGCGTTGCCATGGCCCAACTCTGTCGTCGATATACCCCCGGGGGTATCTGGATGGGTATCCCCGGCGGCAA
ACGAAGGGTGGATGGATGAG

Downstream 100 bases:

>100_bases
ACACCCACGATGCCGCCAGAACGGCCCACATCGACGTCGCCAGCCTGCGCGAGCTGATGACGGTGGCAGGCCCGCCGCCG
CGCCTGATCGACGTGCGCAC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTIAVEVVETSTLGDRSYLAHDGQLAVVVDPQRDIDRILALAGGIGVRISHVVETHLHNDYVSGGLALARVTGARYGVAA
ADDVHFDRLPLSDGDEITISDEAAMTVVATPGHTFHHLSFLLHGPKGPAGVFTGGSLLFGTTGRTDLLGAQHAHTLARHQ
HASARRLADLLPQGAQVWPTHGFGSFCSASQSDVPASTIGQERTINPVLRLAADDFVTEVLAGLDAFPAYYAHMGARNAG
GADLVDLTPVRVADAGELRSRITAGEWVVDLRSRKAFAHRHLTGTLSLGLDGPMSTWLGWLMSWGMPVTLLGESDAQIGQ
AQRELARIGIDRPAAAATGTPEQWAAGDQSRLGPLPSATYPELAAALAGRPPRGLPAPDVVLDVRLRNEWRNGHLAGAVH
IPLPELPGRLGEVPGEAVWVYCGSGYRAAAAASLLARAGRTAAFIDDSYTAAADAGLPIVSGEGAE

Sequences:

>Translated_466_residues
MTIAVEVVETSTLGDRSYLAHDGQLAVVVDPQRDIDRILALAGGIGVRISHVVETHLHNDYVSGGLALARVTGARYGVAA
ADDVHFDRLPLSDGDEITISDEAAMTVVATPGHTFHHLSFLLHGPKGPAGVFTGGSLLFGTTGRTDLLGAQHAHTLARHQ
HASARRLADLLPQGAQVWPTHGFGSFCSASQSDVPASTIGQERTINPVLRLAADDFVTEVLAGLDAFPAYYAHMGARNAG
GADLVDLTPVRVADAGELRSRITAGEWVVDLRSRKAFAHRHLTGTLSLGLDGPMSTWLGWLMSWGMPVTLLGESDAQIGQ
AQRELARIGIDRPAAAATGTPEQWAAGDQSRLGPLPSATYPELAAALAGRPPRGLPAPDVVLDVRLRNEWRNGHLAGAVH
IPLPELPGRLGEVPGEAVWVYCGSGYRAAAAASLLARAGRTAAFIDDSYTAAADAGLPIVSGEGAE
>Mature_465_residues
TIAVEVVETSTLGDRSYLAHDGQLAVVVDPQRDIDRILALAGGIGVRISHVVETHLHNDYVSGGLALARVTGARYGVAAA
DDVHFDRLPLSDGDEITISDEAAMTVVATPGHTFHHLSFLLHGPKGPAGVFTGGSLLFGTTGRTDLLGAQHAHTLARHQH
ASARRLADLLPQGAQVWPTHGFGSFCSASQSDVPASTIGQERTINPVLRLAADDFVTEVLAGLDAFPAYYAHMGARNAGG
ADLVDLTPVRVADAGELRSRITAGEWVVDLRSRKAFAHRHLTGTLSLGLDGPMSTWLGWLMSWGMPVTLLGESDAQIGQA
QRELARIGIDRPAAAATGTPEQWAAGDQSRLGPLPSATYPELAAALAGRPPRGLPAPDVVLDVRLRNEWRNGHLAGAVHI
PLPELPGRLGEVPGEAVWVYCGSGYRAAAAASLLARAGRTAAFIDDSYTAAADAGLPIVSGEGAE

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=223, Percent_Identity=29.1479820627803, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221330176, Length=221, Percent_Identity=28.9592760180996, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 48845; Mature: 48713

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAVEVVETSTLGDRSYLAHDGQLAVVVDPQRDIDRILALAGGIGVRISHVVETHLHND
CEEEEEEEEECCCCCCCEEECCCEEEEEECCHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
YVSGGLALARVTGARYGVAAADDVHFDRLPLSDGDEITISDEAAMTVVATPGHTFHHLSF
HHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCHHHEEEE
LLHGPKGPAGVFTGGSLLFGTTGRTDLLGAQHAHTLARHQHASARRLADLLPQGAQVWPT
EEECCCCCCCEEECCEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
HGFGSFCSASQSDVPASTIGQERTINPVLRLAADDFVTEVLAGLDAFPAYYAHMGARNAG
CCCCHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GADLVDLTPVRVADAGELRSRITAGEWVVDLRSRKAFAHRHLTGTLSLGLDGPMSTWLGW
CCCEEECCCEEECCHHHHHHHCCCCHHEEEHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
LMSWGMPVTLLGESDAQIGQAQRELARIGIDRPAAAATGTPEQWAAGDQSRLGPLPSATY
HHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCHHCCCCCCCCH
PELAAALAGRPPRGLPAPDVVLDVRLRNEWRNGHLAGAVHIPLPELPGRLGEVPGEAVWV
HHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCHHCCCHHHCCCCCEEEE
YCGSGYRAAAAASLLARAGRTAAFIDDSYTAAADAGLPIVSGEGAE
EECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHCCCCEEECCCCCC
>Mature Secondary Structure 
TIAVEVVETSTLGDRSYLAHDGQLAVVVDPQRDIDRILALAGGIGVRISHVVETHLHND
EEEEEEEEECCCCCCCEEECCCEEEEEECCHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
YVSGGLALARVTGARYGVAAADDVHFDRLPLSDGDEITISDEAAMTVVATPGHTFHHLSF
HHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCHHHEEEE
LLHGPKGPAGVFTGGSLLFGTTGRTDLLGAQHAHTLARHQHASARRLADLLPQGAQVWPT
EEECCCCCCCEEECCEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
HGFGSFCSASQSDVPASTIGQERTINPVLRLAADDFVTEVLAGLDAFPAYYAHMGARNAG
CCCCHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GADLVDLTPVRVADAGELRSRITAGEWVVDLRSRKAFAHRHLTGTLSLGLDGPMSTWLGW
CCCEEECCCEEECCHHHHHHHCCCCHHEEEHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
LMSWGMPVTLLGESDAQIGQAQRELARIGIDRPAAAATGTPEQWAAGDQSRLGPLPSATY
HHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCHHCCCCCCCCH
PELAAALAGRPPRGLPAPDVVLDVRLRNEWRNGHLAGAVHIPLPELPGRLGEVPGEAVWV
HHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCHHCCCHHHCCCCCEEEE
YCGSGYRAAAAASLLARAGRTAAFIDDSYTAAADAGLPIVSGEGAE
EECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]