Click here to switch to the map view.

The map label for this gene is choA [H]

Identifier: 158315156

GI number: 158315156

Start: 3973682

End: 3975316

Strand: Direct

Name: choA [H]

Synonym: Franean1_3356

Alternate gene names: 158315156

Gene position: 3973682-3975316 (Clockwise)

Preceding gene: 158315154

Following gene: 158315157

Centisome position: 44.24

GC content: 70.15

Gene sequence:

>1635_bases
ATGTCTGACAACGCTTCCACACCTCTGGAATCCGGCCCGGGGCTGACCCGCCGGAGGATCCTCGGCACAGTGGCGCTTGG
CGCGGCTGCGGCTGGTGGGCTGGCGGCCGGCCCTGGCAGCGGACGGGCACGGGCCGCCACAGCCCCGGCGGACGCGGCCG
TCACCGAGCAGCGGGAGCGGGCCGTCGTCATCGGCAGCGGATTCGGCGGCGGCGTGACCGCGCTGCGGCTGGCACAGGCC
GGAGTGCCCACTCTTGTCCTGGAGCGTGGCCTGCGGTGGTCGACGGGGCCGAACGCGACGACCTTCTGCCGCTGGGCGAA
CATCGACAACCGGTCCGCCTGGCTGACCGACCACAGCACGACCCCGGGCGTGGACAAGACCTGGACGCCCTACACCGGAG
TGATCGAGAGCCTGCCGGGCGACGGCATAACGGTCAACTGCGGTGCCGGCGTCGGTGGCGGCTCGCTGGTGTACCACGGG
ATGACACTGCAGCCGACCAGCCAGAACTTCGCGGCATCCATCCCGGAGGCCGCGAGTCTCTACCGCGACCTGAACCGGTG
GGCCTACCCCACCGTCGCCACCATGCTGGGCGTCTCCACGGTGCCGAACGACGTGCTGAACGCGGATCAGTACCGGTCGT
CCCGGCTCTTTCTGGACGTGGCCGCCAACAGCGGCCTGGAGCCGTTCCGGGTTCCGCTGCCGGTCGACTGGAGCTACGTC
CGGGGTGAGCTCACCGGTCAGTACGAGCCGACCTACACCACCAGCGACATCGTCTTCGGCGTCAACAACGGCGGCAAGCA
CTCGATCGACGTCACCTACCTGGCCTCGGCCGAGGCCACGGGCCGGGTACGGGTGAGCCCACTGCACGTGGTGCGGGACG
TCCAGATGGACCCGGACGGCCGCTGGGTGCTCTCCGTCGACCGCATCGACACCGGCGGCACCGTGCAGGAGCGGAAGCGG
ATCACCGCGGACGCGGTGTTCCTCAACGCCGGTTCCGCCGGTACCACGCGGCTCCTGGTCAAGGCGCGAGCCAAGGGGCT
GGTGCCCGACCTCCCCGACGCCATCGGCACGAAGTGGGGAAACAACGGTGATCGGATCTACGCCTGGGTCGGCATGAACG
GTGATCCTGGCACCCGGCAGGGCGGCCCGGCGTGTGTGGGCGGCCGGGACACACAGGGGCCGATTCCGGCCACCGTCATC
CATGCGGGTGCGCCCGCCGACACCGGCGGCGTGAAGCTGATGACGGTCGTCGGTTTCGGGATCGTCGACGCCGCTGGCAC
GTGGGCCTACGACCCGAACACGGATGACGCCAGGCTCACCTGGCCGGCGACCGGTGACGCCGCGCTCCAGACCCAGATCG
CCGCCCGGATGCAGGCGATCGTCGCCGCGGGTGGCGGGATGATGATCGACACGAACGCCCAGGCGAACTCGACCTGGCAT
GCCCTGGGCGGGGTGCCGATGGGATCGGCGGTCGACCTGTACGGCCGGATCATCGGCCACAAGGGCCTCTACGTACTCGA
CGGGTCGCGGATCCCGGGCTCCACCGGTGCCTGTAACCCCTCCATGACGATCGCGGCCCTGGCCGAGCACAGCATGTCCA
CGATCATCCGTGAGGACGTCGGACGTGTCTTCTGA

Upstream 100 bases:

>100_bases
CCGGAACCGGCCGAACCACTGCGTTCCCTTGGATCCATACATCGCACCGCCGATACGGGGCGGCGGCCTTTCGCAGTGCG
ACGGAAGAGATGGAGACACC

Downstream 100 bases:

>100_bases
CGGCACCACCGCTTCCTGAGCCTCCGCGCGGCCGCATCCGGCGGGAGCCGTCCAGGTTCCCGCCGTGAGGGCGGCGCTCC
CCGCCCGATGCCCGATGTCC

Product: cholesterol oxidase

Products: NA

Alternate protein names: CHOD [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSDNASTPLESGPGLTRRRILGTVALGAAAAGGLAAGPGSGRARAATAPADAAVTEQRERAVVIGSGFGGGVTALRLAQA
GVPTLVLERGLRWSTGPNATTFCRWANIDNRSAWLTDHSTTPGVDKTWTPYTGVIESLPGDGITVNCGAGVGGGSLVYHG
MTLQPTSQNFAASIPEAASLYRDLNRWAYPTVATMLGVSTVPNDVLNADQYRSSRLFLDVAANSGLEPFRVPLPVDWSYV
RGELTGQYEPTYTTSDIVFGVNNGGKHSIDVTYLASAEATGRVRVSPLHVVRDVQMDPDGRWVLSVDRIDTGGTVQERKR
ITADAVFLNAGSAGTTRLLVKARAKGLVPDLPDAIGTKWGNNGDRIYAWVGMNGDPGTRQGGPACVGGRDTQGPIPATVI
HAGAPADTGGVKLMTVVGFGIVDAAGTWAYDPNTDDARLTWPATGDAALQTQIAARMQAIVAAGGGMMIDTNAQANSTWH
ALGGVPMGSAVDLYGRIIGHKGLYVLDGSRIPGSTGACNPSMTIAALAEHSMSTIIREDVGRVF

Sequences:

>Translated_544_residues
MSDNASTPLESGPGLTRRRILGTVALGAAAAGGLAAGPGSGRARAATAPADAAVTEQRERAVVIGSGFGGGVTALRLAQA
GVPTLVLERGLRWSTGPNATTFCRWANIDNRSAWLTDHSTTPGVDKTWTPYTGVIESLPGDGITVNCGAGVGGGSLVYHG
MTLQPTSQNFAASIPEAASLYRDLNRWAYPTVATMLGVSTVPNDVLNADQYRSSRLFLDVAANSGLEPFRVPLPVDWSYV
RGELTGQYEPTYTTSDIVFGVNNGGKHSIDVTYLASAEATGRVRVSPLHVVRDVQMDPDGRWVLSVDRIDTGGTVQERKR
ITADAVFLNAGSAGTTRLLVKARAKGLVPDLPDAIGTKWGNNGDRIYAWVGMNGDPGTRQGGPACVGGRDTQGPIPATVI
HAGAPADTGGVKLMTVVGFGIVDAAGTWAYDPNTDDARLTWPATGDAALQTQIAARMQAIVAAGGGMMIDTNAQANSTWH
ALGGVPMGSAVDLYGRIIGHKGLYVLDGSRIPGSTGACNPSMTIAALAEHSMSTIIREDVGRVF
>Mature_543_residues
SDNASTPLESGPGLTRRRILGTVALGAAAAGGLAAGPGSGRARAATAPADAAVTEQRERAVVIGSGFGGGVTALRLAQAG
VPTLVLERGLRWSTGPNATTFCRWANIDNRSAWLTDHSTTPGVDKTWTPYTGVIESLPGDGITVNCGAGVGGGSLVYHGM
TLQPTSQNFAASIPEAASLYRDLNRWAYPTVATMLGVSTVPNDVLNADQYRSSRLFLDVAANSGLEPFRVPLPVDWSYVR
GELTGQYEPTYTTSDIVFGVNNGGKHSIDVTYLASAEATGRVRVSPLHVVRDVQMDPDGRWVLSVDRIDTGGTVQERKRI
TADAVFLNAGSAGTTRLLVKARAKGLVPDLPDAIGTKWGNNGDRIYAWVGMNGDPGTRQGGPACVGGRDTQGPIPATVIH
AGAPADTGGVKLMTVVGFGIVDAAGTWAYDPNTDDARLTWPATGDAALQTQIAARMQAIVAAGGGMMIDTNAQANSTWHA
LGGVPMGSAVDLYGRIIGHKGLYVLDGSRIPGSTGACNPSMTIAALAEHSMSTIIREDVGRVF

Specific function: Unknown

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867
- InterPro:   IPR006311 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.3.6 [H]

Molecular weight: Translated: 56492; Mature: 56361

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNASTPLESGPGLTRRRILGTVALGAAAAGGLAAGPGSGRARAATAPADAAVTEQRER
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHCCCC
AVVIGSGFGGGVTALRLAQAGVPTLVLERGLRWSTGPNATTFCRWANIDNRSAWLTDHST
EEEEECCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEECCCC
TPGVDKTWTPYTGVIESLPGDGITVNCGAGVGGGSLVYHGMTLQPTSQNFAASIPEAASL
CCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCCEEEECEEECCCCCCHHHCCCHHHHH
YRDLNRWAYPTVATMLGVSTVPNDVLNADQYRSSRLFLDVAANSGLEPFRVPLPVDWSYV
HHHHHHHCCHHHHHHHCCCCCCHHHHCCHHHCCCEEEEEEECCCCCCCEECCCCCCHHHH
RGELTGQYEPTYTTSDIVFGVNNGGKHSIDVTYLASAEATGRVRVSPLHVVRDVQMDPDG
CCEECCCCCCCEECCEEEEEECCCCCEEEEEEEEECCCCCCEEEECCEEEEEECEECCCC
RWVLSVDRIDTGGTVQERKRITADAVFLNAGSAGTTRLLVKARAKGLVPDLPDAIGTKWG
CEEEEEECCCCCCCHHHHHHEEEEEEEEECCCCCCEEEEEEHHHCCCCCCCCHHHCCCCC
NNGDRIYAWVGMNGDPGTRQGGPACVGGRDTQGPIPATVIHAGAPADTGGVKLMTVVGFG
CCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCC
IVDAAGTWAYDPNTDDARLTWPATGDAALQTQIAARMQAIVAAGGGMMIDTNAQANSTWH
CEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
ALGGVPMGSAVDLYGRIIGHKGLYVLDGSRIPGSTGACNPSMTIAALAEHSMSTIIREDV
EECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GRVF
HCCC
>Mature Secondary Structure 
SDNASTPLESGPGLTRRRILGTVALGAAAAGGLAAGPGSGRARAATAPADAAVTEQRER
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHCCCC
AVVIGSGFGGGVTALRLAQAGVPTLVLERGLRWSTGPNATTFCRWANIDNRSAWLTDHST
EEEEECCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEECCCC
TPGVDKTWTPYTGVIESLPGDGITVNCGAGVGGGSLVYHGMTLQPTSQNFAASIPEAASL
CCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCCEEEECEEECCCCCCHHHCCCHHHHH
YRDLNRWAYPTVATMLGVSTVPNDVLNADQYRSSRLFLDVAANSGLEPFRVPLPVDWSYV
HHHHHHHCCHHHHHHHCCCCCCHHHHCCHHHCCCEEEEEEECCCCCCCEECCCCCCHHHH
RGELTGQYEPTYTTSDIVFGVNNGGKHSIDVTYLASAEATGRVRVSPLHVVRDVQMDPDG
CCEECCCCCCCEECCEEEEEECCCCCEEEEEEEEECCCCCCEEEECCEEEEEECEECCCC
RWVLSVDRIDTGGTVQERKRITADAVFLNAGSAGTTRLLVKARAKGLVPDLPDAIGTKWG
CEEEEEECCCCCCCHHHHHHEEEEEEEEECCCCCCEEEEEEHHHCCCCCCCCHHHCCCCC
NNGDRIYAWVGMNGDPGTRQGGPACVGGRDTQGPIPATVIHAGAPADTGGVKLMTVVGFG
CCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCC
IVDAAGTWAYDPNTDDARLTWPATGDAALQTQIAARMQAIVAAGGGMMIDTNAQANSTWH
CEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
ALGGVPMGSAVDLYGRIIGHKGLYVLDGSRIPGSTGACNPSMTIAALAEHSMSTIIREDV
EECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GRVF
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2914858; 10194345 [H]