BacMap

Definition	Frankia sp. EAN1pec chromosome, complete genome.
Accession	NC_009921
Length	8,982,042

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The map label for this gene is bdhA [H]

Identifier: 158315090

GI number: 158315090

Start: 3896208

End: 3897026

Strand: Direct

Name: bdhA [H]

Synonym: Franean1_3289

Alternate gene names: 158315090

Gene position: 3896208-3897026 (Clockwise)

Preceding gene: 158315089

Following gene: 158315092

Centisome position: 43.38

GC content: 68.01

Gene sequence:

>819_bases
GTGGAGACAGGACTGAACGGCCGTACCGTACTGATCACGGGCGGGAGCGCCAACATCGGCCGGGGTATAGCCCTGGCCTT
CGCCGCGGAGGGCTCGAACGTCGTCGTGGTCGGCCGCGACGAGGCCCAGGGCCGCCGGGTATGTGACGCTGTCCTGGAAC
GCGGCGCCGGGCAGGTGCTCTGGTGGGCCGCTGCTGTCACCGACCGTGCCCAGGTCGGCGCCATGGTGGCCGCGACACAT
GAGCGGTTCGGAGCGCTGGACGTGCTCGTGAACAATGCCGGCGGAAACGCGGAGTTCGCGGAGTTCGTCAACAGCGATCC
GACGGTCTGGGAGAAGGACATCTCCCTCAACATCGCGAGCACGCTGAACTGCACCCATGCGGCGCTCCCTGGCATGATCG
AACGAGGGTGCGGGCGGGTCATCAACATCGGGTCGACGTCCGCGATCCTGGGTGATCCCCTGATGGCGGTGTATTCGGCG
ATGAAAGGGGCGGTGCACGCCTTCACCAGGGTGCTCGCCAGGGAGGTCGGGAAACAGGGCATCACGGTCAACGCCATCGC
CCCCTACGCGACCATGCCGCTGGACTACGAGCAGGAGGTCAACTCGGGTAGTCGGTGGCATCCGGACGGGATCGTCGCGC
GGCTGGCCGCCACCCGGTCGACGGAGGAGCTGCGCCTGATGAGCCGCCGCACGGTCCTCGATCGTCAGTTCGCCTTTCCC
GCGGAGATCGGCGCTGCTGCCGTCTACCTCGCCTCGGACGGGGCCGCTTTCGTGACCGGTCAGGTGCTCGCCGTCGACGG
TGGCACGCAACTCGCCTGA

Upstream 100 bases:

>100_bases
GTCCGCCTCTGGACCGAAGGCGAGAAGCGGCTGGCCGGGCGGGGCTGTCTGGAGAGGGGCTACCTGTAGAGGCTGCTGGC
CGCGAGCTCAGGAGGCTGTG

Downstream 100 bases:

>100_bases
CAACCGACCGGCGATCCGCGAGTACGGAACGGACCTCGTCTGCCGCACGCTTGTTCCGCCGTGCTCCCGCGGGGTGCTTG
GGATCGCGCGGAACACGGTG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
METGLNGRTVLITGGSANIGRGIALAFAAEGSNVVVVGRDEAQGRRVCDAVLERGAGQVLWWAAAVTDRAQVGAMVAATH
ERFGALDVLVNNAGGNAEFAEFVNSDPTVWEKDISLNIASTLNCTHAALPGMIERGCGRVINIGSTSAILGDPLMAVYSA
MKGAVHAFTRVLAREVGKQGITVNAIAPYATMPLDYEQEVNSGSRWHPDGIVARLAATRSTEELRLMSRRTVLDRQFAFP
AEIGAAAVYLASDGAAFVTGQVLAVDGGTQLA

Sequences:

>Translated_272_residues
METGLNGRTVLITGGSANIGRGIALAFAAEGSNVVVVGRDEAQGRRVCDAVLERGAGQVLWWAAAVTDRAQVGAMVAATH
ERFGALDVLVNNAGGNAEFAEFVNSDPTVWEKDISLNIASTLNCTHAALPGMIERGCGRVINIGSTSAILGDPLMAVYSA
MKGAVHAFTRVLAREVGKQGITVNAIAPYATMPLDYEQEVNSGSRWHPDGIVARLAATRSTEELRLMSRRTVLDRQFAFP
AEIGAAAVYLASDGAAFVTGQVLAVDGGTQLA
>Mature_272_residues
METGLNGRTVLITGGSANIGRGIALAFAAEGSNVVVVGRDEAQGRRVCDAVLERGAGQVLWWAAAVTDRAQVGAMVAATH
ERFGALDVLVNNAGGNAEFAEFVNSDPTVWEKDISLNIASTLNCTHAALPGMIERGCGRVINIGSTSAILGDPLMAVYSA
MKGAVHAFTRVLAREVGKQGITVNAIAPYATMPLDYEQEVNSGSRWHPDGIVARLAATRSTEELRLMSRRTVLDRQFAFP
AEIGAAAVYLASDGAAFVTGQVLAVDGGTQLA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=248, Percent_Identity=33.4677419354839, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI7705855, Length=191, Percent_Identity=30.3664921465969, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI66933014, Length=272, Percent_Identity=31.6176470588235, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI32483357, Length=275, Percent_Identity=26.9090909090909, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=260, Percent_Identity=27.6923076923077, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI19923817, Length=272, Percent_Identity=25.3676470588235, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI7706318, Length=191, Percent_Identity=31.9371727748691, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7705925, Length=272, Percent_Identity=29.0441176470588, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=30.8900523560209, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=34.3434343434343, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI226371731, Length=187, Percent_Identity=27.807486631016, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI32455239, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5031765, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20149619, Length=208, Percent_Identity=29.3269230769231, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=30.2197802197802, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI10190704, Length=274, Percent_Identity=29.1970802919708, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4557649, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI33667109, Length=207, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI15277342, Length=278, Percent_Identity=25.1798561151079, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI5031737, Length=192, Percent_Identity=31.25, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI40807363, Length=186, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=269, Percent_Identity=32.3420074349442, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787335, Length=267, Percent_Identity=31.8352059925094, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87082160, Length=271, Percent_Identity=29.1512915129151, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790717, Length=272, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1789378, Length=271, Percent_Identity=25.830258302583, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789208, Length=273, Percent_Identity=29.6703296703297, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787905, Length=264, Percent_Identity=28.4090909090909, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788459, Length=276, Percent_Identity=26.4492753623188, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367175, Length=262, Percent_Identity=28.2442748091603, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787526, Length=189, Percent_Identity=29.1005291005291, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367365, Length=269, Percent_Identity=30.1115241635688, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=31.6666666666667, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=271, Percent_Identity=26.1992619926199, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=261, Percent_Identity=28.735632183908, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=27.7372262773723, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=266, Percent_Identity=25.187969924812, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=281, Percent_Identity=29.1814946619217, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=265, Percent_Identity=28.3018867924528, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=288, Percent_Identity=26.3888888888889, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=283, Percent_Identity=27.208480565371, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=285, Percent_Identity=27.0175438596491, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=298, Percent_Identity=27.1812080536913, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=278, Percent_Identity=26.978417266187, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=286, Percent_Identity=26.5734265734266, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=278, Percent_Identity=27.6978417266187, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=214, Percent_Identity=28.9719626168224, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=288, Percent_Identity=26.3888888888889, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=279, Percent_Identity=27.5985663082437, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=274, Percent_Identity=27.3722627737226, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=275, Percent_Identity=25.4545454545455, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=281, Percent_Identity=25.9786476868327, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=282, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=211, Percent_Identity=24.6445497630332, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=187, Percent_Identity=28.8770053475936, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25152911, Length=211, Percent_Identity=29.8578199052133, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=194, Percent_Identity=33.5051546391753, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=269, Percent_Identity=24.907063197026, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212646214, Length=189, Percent_Identity=28.042328042328, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=184, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=268, Percent_Identity=28.3582089552239, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=274, Percent_Identity=27.3722627737226, Blast_Score=82, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=28.8659793814433, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=29.8969072164948, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21357041, Length=261, Percent_Identity=28.735632183908, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571526, Length=266, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644339, Length=265, Percent_Identity=27.1698113207547, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI23397609, Length=271, Percent_Identity=29.1512915129151, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21356301, Length=205, Percent_Identity=29.7560975609756, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161076933, Length=255, Percent_Identity=28.2352941176471, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24584744, Length=209, Percent_Identity=28.2296650717703, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574402, Length=210, Percent_Identity=28.0952380952381, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584748, Length=209, Percent_Identity=29.1866028708134, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21358495, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640442, Length=188, Percent_Identity=28.1914893617021, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364892, Length=212, Percent_Identity=28.7735849056604, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859837, Length=193, Percent_Identity=29.0155440414508, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24639444, Length=269, Percent_Identity=26.0223048327138, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24644337, Length=273, Percent_Identity=29.6703296703297, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581726, Length=190, Percent_Identity=28.4210526315789, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24580925, Length=211, Percent_Identity=28.9099526066351, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737361, Length=190, Percent_Identity=30, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=26.4248704663212, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 28427; Mature: 28427

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METGLNGRTVLITGGSANIGRGIALAFAAEGSNVVVVGRDEAQGRRVCDAVLERGAGQVL
CCCCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCEE
WWAAAVTDRAQVGAMVAATHERFGALDVLVNNAGGNAEFAEFVNSDPTVWEKDISLNIAS
EEEEHHHCHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHCCCCCEEECCEEEEEHH
TLNCTHAALPGMIERGCGRVINIGSTSAILGDPLMAVYSAMKGAVHAFTRVLAREVGKQG
HCCCHHHHHHHHHHHCCCCEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ITVNAIAPYATMPLDYEQEVNSGSRWHPDGIVARLAATRSTEELRLMSRRTVLDRQFAFP
EEEEEECCCEECCCCHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
AEIGAAAVYLASDGAAFVTGQVLAVDGGTQLA
HHHCCEEEEEECCCCEEEEEEEEEECCCCCCC
>Mature Secondary Structure
METGLNGRTVLITGGSANIGRGIALAFAAEGSNVVVVGRDEAQGRRVCDAVLERGAGQVL
CCCCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCEE
WWAAAVTDRAQVGAMVAATHERFGALDVLVNNAGGNAEFAEFVNSDPTVWEKDISLNIAS
EEEEHHHCHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHCCCCCEEECCEEEEEHH
TLNCTHAALPGMIERGCGRVINIGSTSAILGDPLMAVYSAMKGAVHAFTRVLAREVGKQG
HCCCHHHHHHHHHHHCCCCEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ITVNAIAPYATMPLDYEQEVNSGSRWHPDGIVARLAATRSTEELRLMSRRTVLDRQFAFP
EEEEEECCCEECCCCHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
AEIGAAAVYLASDGAAFVTGQVLAVDGGTQLA
HHHCCEEEEEECCCCEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]