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The map label for this gene is coxL [H]

Identifier: 158315017

GI number: 158315017

Start: 3788847

End: 3791216

Strand: Direct

Name: coxL [H]

Synonym: Franean1_3211

Alternate gene names: 158315017

Gene position: 3788847-3791216 (Clockwise)

Preceding gene: 158315016

Following gene: 158315022

Centisome position: 42.18

GC content: 70.08

Gene sequence:

>2370_bases
ATGGGGAACTCCACTGTCACGACAGCCGCCGCCACGCCGACCGCCGCGCGGTACGCGGGCACCCGCGTGAACCGGGTCGA
GGACCCGCGGCTGCTTACCGGCCAGGGCACCTATGTCGACGATGTCAAGCGGCCGGGGATGCTGCACGCGTGCTTTGTAC
GCAGCCCGTTCGCCCGCGCGCGCATCATCGGCATCGACGCGTCGTCGGCGTTGGAGCTCGAGGGCGTGCACGCCGTGTTC
GTGGCCGAGGATCTCAACCCGGGCGTCCACGAGCACTGGTTCGGGATCATCGGTCGCGACGTCCCGGACACCCCGCGGCC
GGCGCTGGCCCAGGACGAGGTCCGCTTCGTCGGCGACCCGGTGGCCCTCGTCATCGCGGAGGACCGCTACATCGCGGAGG
ACGCGGTTGAGCTGGTGGAGGTGGATTACGACCCGCTGCCTCCGGTCGCCTCCTACATCAGCGCCCAGGAGTCGACCGAG
CTCGTGCACGAGGCCTACCAGAACAACCGGGCCGGACTACTCAAAGGCGGCGACCAGGGGCGGGTCGACGAGGCGTGCGC
CGGCGCGGCGTTCGTCGTCGAGGAGACGATCTACCAGCAGGGGTACGCGCCCGTCCCGATGGAGACCCGCGGGATCGTCG
TGGAGTGGTCGGGTGGCGAGCTCACGATCTGGGCGGCGTCCCAGGCCCCCCATGAGCTGCGGGCCTTCGCCGCGCGGTAC
CTCGGCCTGCCGGAGAACCGGGTTCGCGTGATCATGCGGGACGCGGGCGGGGGCTTCGGGCAGAAGGTCAACCCGATGCG
CGAGGACATGTGCATGCTGCTCGCCGCCCGGAAGGTTCCCGCGGCGCTGAAGTGGATCGAGGACCGGCGCGAGAACCTCA
TGGCCGCGAACTCGGCCCGCCACGAGCACGGTGCCGCCCGTCTCGCGTTCGACGCGGAGGGCAGGATCGTCGCGGCGCAG
ATCGACCATGTCCAGGACGTGGGTTCCTACCCCACACCGTGGCCGGTGGGTACCGCGGTGGCGGTCTGCATGATGTTCCC
CGGGCCGTACCGCATCCCGGTCGCGGCGTGGTCGTCGGCGTCGGTGTTCTCGAACACGCTGGGTCGTGGCGCCTACCGGG
GGCCGTGGCAGTACGAGTCGGTCGCTCGCGAGGTACTGCTGGACGTCGCCGCGCGCCGGATGGGCCTCGACCCGGTCGAG
CTGCGCCGGCGCAACTTCCTGGCCCGCGCGGACCTGCCGTACGTGAACCCGTGCGGCATGCCGTACGACCACATGTCCCC
GCGTGAGGTGTTCGAGAAGGCACTGGAGCACTTCGACTACGACGCGTTCCGCCGTGAGCAGGCCGAGGCCAGGGCGAACG
GCCGGTACATCGGTATCGGGACGTGCAGCTACGTGGAGCCCACCACGACCGGGATGTCCTTCTACGCGACCGAGGGCGCC
ACGATCCGCATCGAGCCGAGTGGCACGGTCAACGTGTACCTCGCTGGCGGATCGACGGGCAACAGCCTGGAGACCACCGC
CGTACAGATCGCGGCCGACGCGCTGGGTGTCGACATCAGGGACGTCAACACGATCCAGGGAGACACCGCCGTCACGCCCT
TCGGCGGGGGCACCGGCGGCAGTCGCAGCGGTTCGATGATCGCCGGGGCGGTCGGAGTCACCGCGGGCGAACTACGCGAG
CGCATCATCGCCATCGCGGCGCACCGTCTGGAGGCGGCGGCCGAGGACATCGAGCTCGCGGACGGGCGGGCCAATGTGCG
TGGTACCCCCTCGATCGGCATGTCGCTCGCCGAGATCGCGAATGTCGCGTATTTCGATCCCGCCGGGCTGCCGCCCGGTG
TGCAGCCCGGATTGGAAGTCAGCGGCCGGTATCAGGCGCAGGCGCCGATGCTGTGGGCCAACGCCACGCACATCTGTACC
TGCGAGGTGGACACGGAGACCGGGGTCGTGACCTTCCTTCGGTACCTCGTCAGCGAGGACTGCGGCCCGCGGATCAACCC
GAGCATCGTCGAGGGCCAGGTCGACGGTGGAACCGTGCAGGGCATCGGCGGGGCTCTCTACGAGGACCTGGCCTATGACG
AGGACGGCAACCCGGTCGCGACGACGTTCATCGACTACCTGTTGCCGACCATCGCCGAGATGCCGCTCATCGAGCACGTG
CACCTCGAGACCCCGGGACCGGGGCCGGGCGGCTACAAAGGCGCCGGTGAGGGCGGCGCGATCGGCGCGCCCCCGGCAGT
CATCAACGCGGTCGCCGACGCGCTCGCGCCGTTCGGGGTCTCCATCACCCACCTTCCGCTCACGCCCGCGACGATTGTCG
CGCTTCTCGACGAGGGGAAGTCCGGCCAGGAGGACCAGCAGCCTCACTGA

Upstream 100 bases:

>100_bases
TCTCACCACTCGGGGCAGGGGGCCCCGGGCCCGCACGCATCCGGCGTAGTGACAGGCGGCGTGCTCCTCTTTTCCACCAC
CGTTCGTTCCGGAAGGCGTC

Downstream 100 bases:

>100_bases
AGACAGTTCGTCCCCGGGCGCGTCCACCGCGCCCGGGCCGACGGACCACGGCCGCAGCCGTGGTCCGAGGCCTCCGGGGC
GGGCCCTACAGATCGCCGTG

Product: carbon-monoxide dehydrogenase (acceptor)

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 789; Mature: 788

Protein sequence:

>789_residues
MGNSTVTTAAATPTAARYAGTRVNRVEDPRLLTGQGTYVDDVKRPGMLHACFVRSPFARARIIGIDASSALELEGVHAVF
VAEDLNPGVHEHWFGIIGRDVPDTPRPALAQDEVRFVGDPVALVIAEDRYIAEDAVELVEVDYDPLPPVASYISAQESTE
LVHEAYQNNRAGLLKGGDQGRVDEACAGAAFVVEETIYQQGYAPVPMETRGIVVEWSGGELTIWAASQAPHELRAFAARY
LGLPENRVRVIMRDAGGGFGQKVNPMREDMCMLLAARKVPAALKWIEDRRENLMAANSARHEHGAARLAFDAEGRIVAAQ
IDHVQDVGSYPTPWPVGTAVAVCMMFPGPYRIPVAAWSSASVFSNTLGRGAYRGPWQYESVAREVLLDVAARRMGLDPVE
LRRRNFLARADLPYVNPCGMPYDHMSPREVFEKALEHFDYDAFRREQAEARANGRYIGIGTCSYVEPTTTGMSFYATEGA
TIRIEPSGTVNVYLAGGSTGNSLETTAVQIAADALGVDIRDVNTIQGDTAVTPFGGGTGGSRSGSMIAGAVGVTAGELRE
RIIAIAAHRLEAAAEDIELADGRANVRGTPSIGMSLAEIANVAYFDPAGLPPGVQPGLEVSGRYQAQAPMLWANATHICT
CEVDTETGVVTFLRYLVSEDCGPRINPSIVEGQVDGGTVQGIGGALYEDLAYDEDGNPVATTFIDYLLPTIAEMPLIEHV
HLETPGPGPGGYKGAGEGGAIGAPPAVINAVADALAPFGVSITHLPLTPATIVALLDEGKSGQEDQQPH

Sequences:

>Translated_789_residues
MGNSTVTTAAATPTAARYAGTRVNRVEDPRLLTGQGTYVDDVKRPGMLHACFVRSPFARARIIGIDASSALELEGVHAVF
VAEDLNPGVHEHWFGIIGRDVPDTPRPALAQDEVRFVGDPVALVIAEDRYIAEDAVELVEVDYDPLPPVASYISAQESTE
LVHEAYQNNRAGLLKGGDQGRVDEACAGAAFVVEETIYQQGYAPVPMETRGIVVEWSGGELTIWAASQAPHELRAFAARY
LGLPENRVRVIMRDAGGGFGQKVNPMREDMCMLLAARKVPAALKWIEDRRENLMAANSARHEHGAARLAFDAEGRIVAAQ
IDHVQDVGSYPTPWPVGTAVAVCMMFPGPYRIPVAAWSSASVFSNTLGRGAYRGPWQYESVAREVLLDVAARRMGLDPVE
LRRRNFLARADLPYVNPCGMPYDHMSPREVFEKALEHFDYDAFRREQAEARANGRYIGIGTCSYVEPTTTGMSFYATEGA
TIRIEPSGTVNVYLAGGSTGNSLETTAVQIAADALGVDIRDVNTIQGDTAVTPFGGGTGGSRSGSMIAGAVGVTAGELRE
RIIAIAAHRLEAAAEDIELADGRANVRGTPSIGMSLAEIANVAYFDPAGLPPGVQPGLEVSGRYQAQAPMLWANATHICT
CEVDTETGVVTFLRYLVSEDCGPRINPSIVEGQVDGGTVQGIGGALYEDLAYDEDGNPVATTFIDYLLPTIAEMPLIEHV
HLETPGPGPGGYKGAGEGGAIGAPPAVINAVADALAPFGVSITHLPLTPATIVALLDEGKSGQEDQQPH
>Mature_788_residues
GNSTVTTAAATPTAARYAGTRVNRVEDPRLLTGQGTYVDDVKRPGMLHACFVRSPFARARIIGIDASSALELEGVHAVFV
AEDLNPGVHEHWFGIIGRDVPDTPRPALAQDEVRFVGDPVALVIAEDRYIAEDAVELVEVDYDPLPPVASYISAQESTEL
VHEAYQNNRAGLLKGGDQGRVDEACAGAAFVVEETIYQQGYAPVPMETRGIVVEWSGGELTIWAASQAPHELRAFAARYL
GLPENRVRVIMRDAGGGFGQKVNPMREDMCMLLAARKVPAALKWIEDRRENLMAANSARHEHGAARLAFDAEGRIVAAQI
DHVQDVGSYPTPWPVGTAVAVCMMFPGPYRIPVAAWSSASVFSNTLGRGAYRGPWQYESVAREVLLDVAARRMGLDPVEL
RRRNFLARADLPYVNPCGMPYDHMSPREVFEKALEHFDYDAFRREQAEARANGRYIGIGTCSYVEPTTTGMSFYATEGAT
IRIEPSGTVNVYLAGGSTGNSLETTAVQIAADALGVDIRDVNTIQGDTAVTPFGGGTGGSRSGSMIAGAVGVTAGELRER
IIAIAAHRLEAAAEDIELADGRANVRGTPSIGMSLAEIANVAYFDPAGLPPGVQPGLEVSGRYQAQAPMLWANATHICTC
EVDTETGVVTFLRYLVSEDCGPRINPSIVEGQVDGGTVQGIGGALYEDLAYDEDGNPVATTFIDYLLPTIAEMPLIEHVH
LETPGPGPGGYKGAGEGGAIGAPPAVINAVADALAPFGVSITHLPLTPATIVALLDEGKSGQEDQQPH

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=746, Percent_Identity=25.201072386059, Blast_Score=153, Evalue=7e-37,
Organism=Homo sapiens, GI71773480, Length=771, Percent_Identity=24.7730220492866, Blast_Score=141, Evalue=2e-33,
Organism=Escherichia coli, GI1789230, Length=773, Percent_Identity=30.4010349288486, Blast_Score=239, Evalue=7e-64,
Organism=Escherichia coli, GI1789246, Length=819, Percent_Identity=24.9084249084249, Blast_Score=185, Evalue=1e-47,
Organism=Escherichia coli, GI1786478, Length=770, Percent_Identity=25.974025974026, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=750, Percent_Identity=24.2666666666667, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI32566215, Length=754, Percent_Identity=22.1485411140584, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=751, Percent_Identity=22.5033288948069, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17737937, Length=742, Percent_Identity=27.6280323450135, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24647193, Length=748, Percent_Identity=23.9304812834225, Blast_Score=104, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84068; Mature: 83937

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNSTVTTAAATPTAARYAGTRVNRVEDPRLLTGQGTYVDDVKRPGMLHACFVRSPFARA
CCCCEEEEECCCCCHHHHCCCCCCCCCCCEEEECCCCCHHHHCCCCCEEEHHHCCCCCCE
RIIGIDASSALELEGVHAVFVAEDLNPGVHEHWFGIIGRDVPDTPRPALAQDEVRFVGDP
EEEEECCCCCEEECCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCC
VALVIAEDRYIAEDAVELVEVDYDPLPPVASYISAQESTELVHEAYQNNRAGLLKGGDQG
EEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
RVDEACAGAAFVVEETIYQQGYAPVPMETRGIVVEWSGGELTIWAASQAPHELRAFAARY
CCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHH
LGLPENRVRVIMRDAGGGFGQKVNPMREDMCMLLAARKVPAALKWIEDRRENLMAANSAR
HCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCH
HEHGAARLAFDAEGRIVAAQIDHVQDVGSYPTPWPVGTAVAVCMMFPGPYRIPVAAWSSA
HHCCCEEEEECCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCH
SVFSNTLGRGAYRGPWQYESVAREVLLDVAARRMGLDPVELRRRNFLARADLPYVNPCGM
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
PYDHMSPREVFEKALEHFDYDAFRREQAEARANGRYIGIGTCSYVEPTTTGMSFYATEGA
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCC
TIRIEPSGTVNVYLAGGSTGNSLETTAVQIAADALGVDIRDVNTIQGDTAVTPFGGGTGG
EEEECCCCEEEEEEECCCCCCCCHHHHEEEEHHHHCCEEECCCEECCCCEECCCCCCCCC
SRSGSMIAGAVGVTAGELRERIIAIAAHRLEAAAEDIELADGRANVRGTPSIGMSLAEIA
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHCHHHHHHH
NVAYFDPAGLPPGVQPGLEVSGRYQAQAPMLWANATHICTCEVDTETGVVTFLRYLVSED
CEEEECCCCCCCCCCCCCCCCCCEECCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHCC
CGPRINPSIVEGQVDGGTVQGIGGALYEDLAYDEDGNPVATTFIDYLLPTIAEMPLIEHV
CCCCCCCCEEEECCCCCEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
HLETPGPGPGGYKGAGEGGAIGAPPAVINAVADALAPFGVSITHLPLTPATIVALLDEGK
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCC
SGQEDQQPH
CCCCCCCCC
>Mature Secondary Structure 
GNSTVTTAAATPTAARYAGTRVNRVEDPRLLTGQGTYVDDVKRPGMLHACFVRSPFARA
CCCEEEEECCCCCHHHHCCCCCCCCCCCEEEECCCCCHHHHCCCCCEEEHHHCCCCCCE
RIIGIDASSALELEGVHAVFVAEDLNPGVHEHWFGIIGRDVPDTPRPALAQDEVRFVGDP
EEEEECCCCCEEECCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCC
VALVIAEDRYIAEDAVELVEVDYDPLPPVASYISAQESTELVHEAYQNNRAGLLKGGDQG
EEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
RVDEACAGAAFVVEETIYQQGYAPVPMETRGIVVEWSGGELTIWAASQAPHELRAFAARY
CCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHH
LGLPENRVRVIMRDAGGGFGQKVNPMREDMCMLLAARKVPAALKWIEDRRENLMAANSAR
HCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCH
HEHGAARLAFDAEGRIVAAQIDHVQDVGSYPTPWPVGTAVAVCMMFPGPYRIPVAAWSSA
HHCCCEEEEECCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCH
SVFSNTLGRGAYRGPWQYESVAREVLLDVAARRMGLDPVELRRRNFLARADLPYVNPCGM
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
PYDHMSPREVFEKALEHFDYDAFRREQAEARANGRYIGIGTCSYVEPTTTGMSFYATEGA
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCC
TIRIEPSGTVNVYLAGGSTGNSLETTAVQIAADALGVDIRDVNTIQGDTAVTPFGGGTGG
EEEECCCCEEEEEEECCCCCCCCHHHHEEEEHHHHCCEEECCCEECCCCEECCCCCCCCC
SRSGSMIAGAVGVTAGELRERIIAIAAHRLEAAAEDIELADGRANVRGTPSIGMSLAEIA
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHCHHHHHHH
NVAYFDPAGLPPGVQPGLEVSGRYQAQAPMLWANATHICTCEVDTETGVVTFLRYLVSED
CEEEECCCCCCCCCCCCCCCCCCEECCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHCC
CGPRINPSIVEGQVDGGTVQGIGGALYEDLAYDEDGNPVATTFIDYLLPTIAEMPLIEHV
CCCCCCCCEEEECCCCCEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
HLETPGPGPGGYKGAGEGGAIGAPPAVINAVADALAPFGVSITHLPLTPATIVALLDEGK
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCC
SGQEDQQPH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 12515558; 10430865; 12475995 [H]