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The map label for this gene is cutS [H]

Identifier: 158315015

GI number: 158315015

Start: 3787408

End: 3787824

Strand: Direct

Name: cutS [H]

Synonym: Franean1_3209

Alternate gene names: 158315015

Gene position: 3787408-3787824 (Clockwise)

Preceding gene: 158315014

Following gene: 158315016

Centisome position: 42.17

GC content: 71.22

Gene sequence:

>417_bases
GTGGAGCCACGACTCACGCTCGCGGACTTCCTGCGGGAGCACTGCCATCTGACCGGCACGCACCTCGGCTGCGAGCACGG
GGTGTGCGGTGCCTGCACGGTGCTGCTGGACGGCGCGGCGGTGCGCGCGTGCCTCGTCCTCGCGGTGCAGGCCGACGGCT
CCGAGGTCACCACGATCGAAGGCCTCGGCTCTCCTGACGACCTCTCGCCGGTGCAGGTGGCCTTCCAGGAGAACCACGGC
CTGCAGTGCGGGTTCTGCACGCCGGGTTTCGTCGTGTCGGTCACCGCGCTGCTGCGGGACAACCCCGACCCGACCGACGA
GGAGATCCGCGCCGGCCTGTCCGGCAACATCTGCCGCTGCACCGGCTACCAGGGGATCTTCAAGGCGGTCCGGGCCGCGG
CCGGAAAGACGCCGTGA

Upstream 100 bases:

>100_bases
GTGATGGTCGCCCGAGCCTGGCAGCGCGCGGTCCGGGAGGCTCACGATGGATGAAGTCCAGATCAGGCTGCGCGTTAACG
GTACGCAACGCCGCGGCCTG

Downstream 100 bases:

>100_bases
CCATGTGTCGGTCGTACCGCCGACCTGGTGGGGAGGCCTGCCACCCGGCCCCGGGCGGGTGCCGCGCCGCTCGGCCACAC
GTCTCCGCCGGCCCCGTCCC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MEPRLTLADFLREHCHLTGTHLGCEHGVCGACTVLLDGAAVRACLVLAVQADGSEVTTIEGLGSPDDLSPVQVAFQENHG
LQCGFCTPGFVVSVTALLRDNPDPTDEEIRAGLSGNICRCTGYQGIFKAVRAAAGKTP

Sequences:

>Translated_138_residues
MEPRLTLADFLREHCHLTGTHLGCEHGVCGACTVLLDGAAVRACLVLAVQADGSEVTTIEGLGSPDDLSPVQVAFQENHG
LQCGFCTPGFVVSVTALLRDNPDPTDEEIRAGLSGNICRCTGYQGIFKAVRAAAGKTP
>Mature_138_residues
MEPRLTLADFLREHCHLTGTHLGCEHGVCGACTVLLDGAAVRACLVLAVQADGSEVTTIEGLGSPDDLSPVQVAFQENHG
LQCGFCTPGFVVSVTALLRDNPDPTDEEIRAGLSGNICRCTGYQGIFKAVRAAAGKTP

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=144, Percent_Identity=45.1388888888889, Blast_Score=101, Evalue=2e-22,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=47.7777777777778, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786480, Length=151, Percent_Identity=49.0066225165563, Blast_Score=145, Evalue=9e-37,
Organism=Escherichia coli, GI1789232, Length=131, Percent_Identity=48.8549618320611, Blast_Score=116, Evalue=6e-28,
Organism=Escherichia coli, GI1789246, Length=110, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17539860, Length=140, Percent_Identity=47.8571428571429, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17540638, Length=144, Percent_Identity=45.8333333333333, Blast_Score=138, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI32566215, Length=147, Percent_Identity=44.2176870748299, Blast_Score=135, Evalue=5e-33,
Organism=Drosophila melanogaster, GI17737937, Length=141, Percent_Identity=44.6808510638298, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24647199, Length=140, Percent_Identity=41.4285714285714, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647201, Length=140, Percent_Identity=40, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647193, Length=142, Percent_Identity=38.7323943661972, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24647197, Length=144, Percent_Identity=36.8055555555556, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24647195, Length=144, Percent_Identity=36.8055555555556, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 14424; Mature: 14424

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
6.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPRLTLADFLREHCHLTGTHLGCEHGVCGACTVLLDGAAVRACLVLAVQADGSEVTTIE
CCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHEEECCCCEEEEEE
GLGSPDDLSPVQVAFQENHGLQCGFCTPGFVVSVTALLRDNPDPTDEEIRAGLSGNICRC
CCCCCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEE
TGYQGIFKAVRAAAGKTP
CCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEPRLTLADFLREHCHLTGTHLGCEHGVCGACTVLLDGAAVRACLVLAVQADGSEVTTIE
CCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHEEECCCCEEEEEE
GLGSPDDLSPVQVAFQENHGLQCGFCTPGFVVSVTALLRDNPDPTDEEIRAGLSGNICRC
CCCCCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEE
TGYQGIFKAVRAAAGKTP
CCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]