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The map label for this gene is yngJ [H]

Identifier: 158314819

GI number: 158314819

Start: 3534406

End: 3535563

Strand: Direct

Name: yngJ [H]

Synonym: Franean1_3004

Alternate gene names: 158314819

Gene position: 3534406-3535563 (Clockwise)

Preceding gene: 158314818

Following gene: 158314820

Centisome position: 39.35

GC content: 62.95

Gene sequence:

>1158_bases
GTGCATCGCACCGTCTTCAATGAGGAGCACGAAGCCTACCGGCAGTCCCTGCGCGCCTTCATCGAGGCCGAGGTGGTACC
CGAATTCGACGCGTGGTTCGCCGCTGGAGAGGTGCCGCGGGAGTTCTACTACAAGCTGGCCAAGCTGGGCAGTTTCGGCA
TCGAGGTGCCAGAGGAGTACGGCGGGGCTGGAATTTCCTCCCACAAGTACACTGCGGTCGAAACCGAAGAGATTACCCGC
GCCGGTGTCTCCTTCGGGGGTTCCAATGTGCACGTCTCGCTGTGTCTACCTTACCTGTTGAACCTGGGCACACCAGAGCA
GAAGCGGCGCTGGCTCCCGGGGTTCGTCGCCGGCGAGTCCATGTTCGCGATTGCGATGACCGAACCGGGCACCGGCTCCG
ATCTTGCGGGCATGCGCACCACCGCGAAGCTTTCCGAGGACCGCAGCCACTATGTGCTCAACGGGGCGAAGACATTCATC
ACCGGCGGTGTCCACGCGGACCAAGTCATCGTCTGTGCACGCACCGCGTCGCCGATAGACACCGACCGTCGGTTCGGGAT
TTCGCTACTGGTGGTGGACACCAGGTCCGAGGGCTACTCGGTTGGTCGCAAGCTCGACAAGCTCGGGCTGCGGGTCTCCG
ACACGGCCGAGCTGGCTTTCCAGGACGTGAAGGTGCCGGTGGAGAATCTACTGGGGGAGGAGAACGCAGGGTTCTACTAT
CTCGGGCAGAACCTGCCGCAGGAGCGGCTCGTGATCGCATACGGCGCCTATGCACAGGCGGCGGCCGCAGTGCGGCTCGC
CAAGCACTATGTCCAGGAGCGCAAGATCTTCGGTCAACCGCTTTCCTCGTTCCAGAACACCAAGTTCGAACTGGCCGCCT
GCCAGGCGGAGGTGGACGCCGCGCAGGCGGTGGCGGACCGGGCGCTGGAGGCCCATGACGCCAATGAGCTCACCGCGGCC
GAAGCAGCATCGGCCAAGCTGTTCTGTACCGAGACGGCGCACCGGGTGATCGACCGTTGCCTGCAGTTGCATGGCGGCTA
TGGGTTTATCAACGAGTTTCCGATCGCCCGGCTGTACGCCGACAACCGGGTGAACCGGATCTACGGTGGAACATCCGAGG
TGATGAAGTTGATTATCGCGAAGGATATGGGCTTGTGA

Upstream 100 bases:

>100_bases
GGAAGCTGCTCGCCAACAACTTGTGACGATATTTAGTTATGTATCATCGGAAAGAATTTTGGTTTACAATCTACTAGCTA
CAGTAGACTGAGAGGAAACC

Downstream 100 bases:

>100_bases
ACCGGGAGGCTGTGATCGTGGCTACGGCCCGGTCCCCGATCGGCCGCGCCGGTAAGGGTTCGCTCAAGGAATTACGTCCC
AACAACCTGGCCGTGCAAAT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MHRTVFNEEHEAYRQSLRAFIEAEVVPEFDAWFAAGEVPREFYYKLAKLGSFGIEVPEEYGGAGISSHKYTAVETEEITR
AGVSFGGSNVHVSLCLPYLLNLGTPEQKRRWLPGFVAGESMFAIAMTEPGTGSDLAGMRTTAKLSEDRSHYVLNGAKTFI
TGGVHADQVIVCARTASPIDTDRRFGISLLVVDTRSEGYSVGRKLDKLGLRVSDTAELAFQDVKVPVENLLGEENAGFYY
LGQNLPQERLVIAYGAYAQAAAAVRLAKHYVQERKIFGQPLSSFQNTKFELAACQAEVDAAQAVADRALEAHDANELTAA
EAASAKLFCTETAHRVIDRCLQLHGGYGFINEFPIARLYADNRVNRIYGGTSEVMKLIIAKDMGL

Sequences:

>Translated_385_residues
MHRTVFNEEHEAYRQSLRAFIEAEVVPEFDAWFAAGEVPREFYYKLAKLGSFGIEVPEEYGGAGISSHKYTAVETEEITR
AGVSFGGSNVHVSLCLPYLLNLGTPEQKRRWLPGFVAGESMFAIAMTEPGTGSDLAGMRTTAKLSEDRSHYVLNGAKTFI
TGGVHADQVIVCARTASPIDTDRRFGISLLVVDTRSEGYSVGRKLDKLGLRVSDTAELAFQDVKVPVENLLGEENAGFYY
LGQNLPQERLVIAYGAYAQAAAAVRLAKHYVQERKIFGQPLSSFQNTKFELAACQAEVDAAQAVADRALEAHDANELTAA
EAASAKLFCTETAHRVIDRCLQLHGGYGFINEFPIARLYADNRVNRIYGGTSEVMKLIIAKDMGL
>Mature_385_residues
MHRTVFNEEHEAYRQSLRAFIEAEVVPEFDAWFAAGEVPREFYYKLAKLGSFGIEVPEEYGGAGISSHKYTAVETEEITR
AGVSFGGSNVHVSLCLPYLLNLGTPEQKRRWLPGFVAGESMFAIAMTEPGTGSDLAGMRTTAKLSEDRSHYVLNGAKTFI
TGGVHADQVIVCARTASPIDTDRRFGISLLVVDTRSEGYSVGRKLDKLGLRVSDTAELAFQDVKVPVENLLGEENAGFYY
LGQNLPQERLVIAYGAYAQAAAAVRLAKHYVQERKIFGQPLSSFQNTKFELAACQAEVDAAQAVADRALEAHDANELTAA
EAASAKLFCTETAHRVIDRCLQLHGGYGFINEFPIARLYADNRVNRIYGGTSEVMKLIIAKDMGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=41.2073490813648, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI226958412, Length=383, Percent_Identity=36.0313315926893, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI226958414, Length=377, Percent_Identity=36.604774535809, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=36.3157894736842, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI21361497, Length=349, Percent_Identity=34.9570200573066, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI7656849, Length=379, Percent_Identity=31.1345646437995, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=30.2872062663185, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=30.2872062663185, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI76496475, Length=391, Percent_Identity=32.2250639386189, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI4557235, Length=391, Percent_Identity=32.2250639386189, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI4501859, Length=380, Percent_Identity=29.2105263157895, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI48976061, Length=338, Percent_Identity=28.4023668639053, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI211971008, Length=338, Percent_Identity=28.4023668639053, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4503943, Length=370, Percent_Identity=25.6756756756757, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI7669494, Length=287, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38505218, Length=281, Percent_Identity=25.6227758007117, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI87081958, Length=373, Percent_Identity=31.3672922252011, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786223, Length=384, Percent_Identity=29.1666666666667, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI87082384, Length=323, Percent_Identity=26.0061919504644, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=386, Percent_Identity=34.4559585492228, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17508101, Length=334, Percent_Identity=35.0299401197605, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17534899, Length=370, Percent_Identity=32.1621621621622, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=29.9212598425197, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17533517, Length=365, Percent_Identity=31.5068493150685, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=33.0532212885154, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=380, Percent_Identity=32.8947368421053, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17570075, Length=375, Percent_Identity=29.6, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=31.6622691292876, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI17506239, Length=333, Percent_Identity=32.7327327327327, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71990804, Length=282, Percent_Identity=33.6879432624113, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=274, Percent_Identity=33.2116788321168, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=26.7195767195767, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=32.9059829059829, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71982178, Length=280, Percent_Identity=27.8571428571429, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=396, Percent_Identity=25, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17531909, Length=244, Percent_Identity=29.0983606557377, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI86563381, Length=276, Percent_Identity=25.7246376811594, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=276, Percent_Identity=25.7246376811594, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355753, Length=385, Percent_Identity=36.1038961038961, Blast_Score=224, Evalue=7e-59,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=34.9206349206349, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=32.9815303430079, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281363737, Length=341, Percent_Identity=32.5513196480938, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24666513, Length=334, Percent_Identity=34.4311377245509, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24660351, Length=384, Percent_Identity=29.6875, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI19920834, Length=395, Percent_Identity=28.8607594936709, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42221; Mature: 42221

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRTVFNEEHEAYRQSLRAFIEAEVVPEFDAWFAAGEVPREFYYKLAKLGSFGIEVPEEY
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHH
GGAGISSHKYTAVETEEITRAGVSFGGSNVHVSLCLPYLLNLGTPEQKRRWLPGFVAGES
CCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCHHHHCCCCCEEECCC
MFAIAMTEPGTGSDLAGMRTTAKLSEDRSHYVLNGAKTFITGGVHADQVIVCARTASPID
EEEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEECCCEEEECCCCCCEEEEEEECCCCCC
TDRRFGISLLVVDTRSEGYSVGRKLDKLGLRVSDTAELAFQDVKVPVENLLGEENAGFYY
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCEEE
LGQNLPQERLVIAYGAYAQAAAAVRLAKHYVQERKIFGQPLSSFQNTKFELAACQAEVDA
ECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEHHHHHHHHH
AQAVADRALEAHDANELTAAEAASAKLFCTETAHRVIDRCLQLHGGYGFINEFPIARLYA
HHHHHHHHHHHCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEC
DNRVNRIYGGTSEVMKLIIAKDMGL
CCCCHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHRTVFNEEHEAYRQSLRAFIEAEVVPEFDAWFAAGEVPREFYYKLAKLGSFGIEVPEEY
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHH
GGAGISSHKYTAVETEEITRAGVSFGGSNVHVSLCLPYLLNLGTPEQKRRWLPGFVAGES
CCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCHHHHCCCCCEEECCC
MFAIAMTEPGTGSDLAGMRTTAKLSEDRSHYVLNGAKTFITGGVHADQVIVCARTASPID
EEEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEECCCEEEECCCCCCEEEEEEECCCCCC
TDRRFGISLLVVDTRSEGYSVGRKLDKLGLRVSDTAELAFQDVKVPVENLLGEENAGFYY
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCEEE
LGQNLPQERLVIAYGAYAQAAAAVRLAKHYVQERKIFGQPLSSFQNTKFELAACQAEVDA
ECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEHHHHHHHHH
AQAVADRALEAHDANELTAAEAASAKLFCTETAHRVIDRCLQLHGGYGFINEFPIARLYA
HHHHHHHHHHHCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCHHCCCCCEEEC
DNRVNRIYGGTSEVMKLIIAKDMGL
CCCCHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]