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The map label for this gene is caiD [C]

Identifier: 158314515

GI number: 158314515

Start: 3184418

End: 3185251

Strand: Direct

Name: caiD [C]

Synonym: Franean1_2691

Alternate gene names: 158314515

Gene position: 3184418-3185251 (Clockwise)

Preceding gene: 158314514

Following gene: 158314516

Centisome position: 35.45

GC content: 70.74

Gene sequence:

>834_bases
GTGAGTCTGACCTGCTTCGACGTTCGCTACGAAGACGGCGTCGCGCATCTGCGGCTCAACCGGCCCGACCAGAAGAACTC
GCTGATCCCGTCGTTCTGGGCCGAGCTGCGGACGCTGGTGACCGACATCGACCGCGAGGCGCGCGCCCGCGTGATCGTCA
TCTCGTCGACCGGCCGGCACTTCTGCGCCGGCCTCGACCTCGGTGTGTTCGTCGGTGGGATGTTCCGGGCGGGCGGCGGC
GGTGACGAGCCCGGCCGCAAGCGGGCGGTGCTCTACCAGGGCATCCGCGTGTTGCAGGAGACGTTCACCGCGCTGGAACG
GGCCCGGCTCCCGGTGATCGCCGCGATCCAGGGCGGCTGCGTCGGCGCGGGGCTCGGCATGGTCTCGGCCTGCGACCTGC
GCTACGCCACCCGCGACGCGTTCTTTCTGGTCCAGGAGACGAACCTCGGCATCACCGCGGAGGTGGGCCAGCTGCAGCGG
CTGCCGAAGGTGATGCCGGAGGGCATCGTCCGGGAGATGGCCTACCGCGGGATGCGCCTACCGGCCGCGCGGGCGGAGGC
GGTCGGATTCGTCAACGCCGTGTTCGACGACCACGACACACTCCTGGCCGCCGTTTCGGAGATCGCGCGTGAGATCGCGT
CGAAGAGCCCGCTGGCGGTCTGGGGCACCAAGCACTCGCTCCATCACGCCCGGGACCACGCCGTCGACGACGGGCTCGAC
CTCGTCGCGCTGTGGCAGGCCGGGATGTACCACCCGGACGACTGCCTGGAGAGCCTGTGCGCCCAGAAGGACCAGCGCAC
GCCGGTCTTCGAGGACCTCCGACCGGCCCCCTGA

Upstream 100 bases:

>100_bases
GGTTCGGCCGGCTCGTGACCGGTCTACGTCTCAACGTGCCCTATGCGGACGACCCCGACGTCTGGACGCCGGTGATTACC
AAGATCAAGGAGTCCGCCCT

Downstream 100 bases:

>100_bases
CGGCCCCAGCCGTCCGGATGGCTGAGACTGCGACGGAAGGAAACCTGACGTGACTGACCAACGCCCCATCGACGCCGACA
ACCACTACTACGAGCCGCTG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSLTCFDVRYEDGVAHLRLNRPDQKNSLIPSFWAELRTLVTDIDREARARVIVISSTGRHFCAGLDLGVFVGGMFRAGGG
GDEPGRKRAVLYQGIRVLQETFTALERARLPVIAAIQGGCVGAGLGMVSACDLRYATRDAFFLVQETNLGITAEVGQLQR
LPKVMPEGIVREMAYRGMRLPAARAEAVGFVNAVFDDHDTLLAAVSEIAREIASKSPLAVWGTKHSLHHARDHAVDDGLD
LVALWQAGMYHPDDCLESLCAQKDQRTPVFEDLRPAP

Sequences:

>Translated_277_residues
MSLTCFDVRYEDGVAHLRLNRPDQKNSLIPSFWAELRTLVTDIDREARARVIVISSTGRHFCAGLDLGVFVGGMFRAGGG
GDEPGRKRAVLYQGIRVLQETFTALERARLPVIAAIQGGCVGAGLGMVSACDLRYATRDAFFLVQETNLGITAEVGQLQR
LPKVMPEGIVREMAYRGMRLPAARAEAVGFVNAVFDDHDTLLAAVSEIAREIASKSPLAVWGTKHSLHHARDHAVDDGLD
LVALWQAGMYHPDDCLESLCAQKDQRTPVFEDLRPAP
>Mature_276_residues
SLTCFDVRYEDGVAHLRLNRPDQKNSLIPSFWAELRTLVTDIDREARARVIVISSTGRHFCAGLDLGVFVGGMFRAGGGG
DEPGRKRAVLYQGIRVLQETFTALERARLPVIAAIQGGCVGAGLGMVSACDLRYATRDAFFLVQETNLGITAEVGQLQRL
PKVMPEGIVREMAYRGMRLPAARAEAVGFVNAVFDDHDTLLAAVSEIAREIASKSPLAVWGTKHSLHHARDHAVDDGLDL
VALWQAGMYHPDDCLESLCAQKDQRTPVFEDLRPAP

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=264, Percent_Identity=40.530303030303, Blast_Score=197, Evalue=6e-51,
Organism=Homo sapiens, GI221136756, Length=218, Percent_Identity=26.605504587156, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI221136753, Length=218, Percent_Identity=26.605504587156, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI221307494, Length=218, Percent_Identity=26.605504587156, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI194097323, Length=262, Percent_Identity=25.5725190839695, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=28.8973384030418, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4757966, Length=218, Percent_Identity=27.0642201834862, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI51538581, Length=218, Percent_Identity=27.0642201834862, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI25453481, Length=218, Percent_Identity=27.0642201834862, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI51538573, Length=218, Percent_Identity=27.0642201834862, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI116235487, Length=189, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI260274832, Length=190, Percent_Identity=27.8947368421053, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI45643119, Length=190, Percent_Identity=27.8947368421053, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI260275230, Length=190, Percent_Identity=27.8947368421053, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4757968, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI49355787, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI221142681, Length=263, Percent_Identity=27.3764258555133, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788682, Length=224, Percent_Identity=29.4642857142857, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082183, Length=273, Percent_Identity=24.9084249084249, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=264, Percent_Identity=34.8484848484849, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17536985, Length=262, Percent_Identity=33.587786259542, Blast_Score=177, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17540714, Length=257, Percent_Identity=28.7937743190661, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=260, Percent_Identity=27.6923076923077, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=265, Percent_Identity=26.0377358490566, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=239, Percent_Identity=26.3598326359833, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=254, Percent_Identity=26.7716535433071, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508951, Length=255, Percent_Identity=27.0588235294118, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=255, Percent_Identity=27.0588235294118, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920382, Length=263, Percent_Identity=36.8821292775665, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24653139, Length=263, Percent_Identity=28.1368821292776, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI20129971, Length=259, Percent_Identity=25.4826254826255, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653477, Length=259, Percent_Identity=25.4826254826255, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24583165, Length=236, Percent_Identity=25.4237288135593, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19921000, Length=194, Percent_Identity=28.8659793814433, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 30310; Mature: 30179

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTCFDVRYEDGVAHLRLNRPDQKNSLIPSFWAELRTLVTDIDREARARVIVISSTGRH
CCEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCHHHCEEEEEEECCCCH
FCAGLDLGVFVGGMFRAGGGGDEPGRKRAVLYQGIRVLQETFTALERARLPVIAAIQGGC
HHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
VGAGLGMVSACDLRYATRDAFFLVQETNLGITAEVGQLQRLPKVMPEGIVREMAYRGMRL
HHHCCCHHHHHHHHHHCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCC
PAARAEAVGFVNAVFDDHDTLLAAVSEIAREIASKSPLAVWGTKHSLHHARDHAVDDGLD
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCH
LVALWQAGMYHPDDCLESLCAQKDQRTPVFEDLRPAP
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCC
>Mature Secondary Structure 
SLTCFDVRYEDGVAHLRLNRPDQKNSLIPSFWAELRTLVTDIDREARARVIVISSTGRH
CEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCHHHCEEEEEEECCCCH
FCAGLDLGVFVGGMFRAGGGGDEPGRKRAVLYQGIRVLQETFTALERARLPVIAAIQGGC
HHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
VGAGLGMVSACDLRYATRDAFFLVQETNLGITAEVGQLQRLPKVMPEGIVREMAYRGMRL
HHHCCCHHHHHHHHHHCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCC
PAARAEAVGFVNAVFDDHDTLLAAVSEIAREIASKSPLAVWGTKHSLHHARDHAVDDGLD
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCH
LVALWQAGMYHPDDCLESLCAQKDQRTPVFEDLRPAP
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA