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The map label for this gene is nrdJ [H]

Identifier: 158314435

GI number: 158314435

Start: 3086749

End: 3087282

Strand: Direct

Name: nrdJ [H]

Synonym: Franean1_2607

Alternate gene names: 158314435

Gene position: 3086749-3087282 (Clockwise)

Preceding gene: 158314433

Following gene: 158314438

Centisome position: 34.37

GC content: 65.17

Gene sequence:

>534_bases
GTGGTTGACGCAACGCCGACGATGGGAATTCGTACGCCCAGCGGCATGGCACGGCGAGCACCGCGCCATCGCCAGTCCGT
GACAAGGGCCTTCACGGTCGGCGGCGCCTACGGTTTCATCATCGCGTCTCTGCACGCCGACGGTTCGTTGGCGGACGTCA
ATCTGATCATGGCGAAGCAGGGGTCCACTTTGCGTGGCCTGACCGAGACCGTCTCGTCGGCGATCTCGACTGGGCTGGCA
CACGGCGTGCCGCTGGTGACGTTCGTCCGGCAGTTCGCCGACCTGCGGTTCGAACCGTCGGGACACACCGACGATCCCGA
GATCCCGCGGGCAACGTCGATCATCGACTATGTGATGAGGCGTCTGGCGTTGGACTTCCTGCCGTTGGACGATCGCACCA
CATTGGGCATGCTCACCCCGCTGGAGCGTGCTGAGATCGCGGCCGAAGCAACACCGGCGCCGCTGTCGTGGTCGGACACG
CCGGGGATATCGATGTCCGGGTCCTTCGAGATCCCGGTCCAGGTCTCGCGCTAA

Upstream 100 bases:

>100_bases
CAACATCTGGCACTTCCCGTTACACGGCGATGCCATCTGTTGTGATCGTTTGCCGGATGTAGTCAGCCAGAATGAACGTG
TCGATCGAGAGGAACGCGCC

Downstream 100 bases:

>100_bases
GACGCTTCTGCTCGCTGAACCGGTTCACACGGTTGCGTGGCAAGCGCGCGACACGTCACGGTCAGTATGCAGTCAATATC
GTCGCTGATCGTATAAACAG

Product: ribonucleotide reductase large subunit

Products: NA

Alternate protein names: Ribonucleoside-diphosphate reductase nrdJ [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MVDATPTMGIRTPSGMARRAPRHRQSVTRAFTVGGAYGFIIASLHADGSLADVNLIMAKQGSTLRGLTETVSSAISTGLA
HGVPLVTFVRQFADLRFEPSGHTDDPEIPRATSIIDYVMRRLALDFLPLDDRTTLGMLTPLERAEIAAEATPAPLSWSDT
PGISMSGSFEIPVQVSR

Sequences:

>Translated_177_residues
MVDATPTMGIRTPSGMARRAPRHRQSVTRAFTVGGAYGFIIASLHADGSLADVNLIMAKQGSTLRGLTETVSSAISTGLA
HGVPLVTFVRQFADLRFEPSGHTDDPEIPRATSIIDYVMRRLALDFLPLDDRTTLGMLTPLERAEIAAEATPAPLSWSDT
PGISMSGSFEIPVQVSR
>Mature_177_residues
MVDATPTMGIRTPSGMARRAPRHRQSVTRAFTVGGAYGFIIASLHADGSLADVNLIMAKQGSTLRGLTETVSSAISTGLA
HGVPLVTFVRQFADLRFEPSGHTDDPEIPRATSIIDYVMRRLALDFLPLDDRTTLGMLTPLERAEIAAEATPAPLSWSDT
PGISMSGSFEIPVQVSR

Specific function: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen [H]

COG id: COG0209

COG function: function code F; Ribonucleotide reductase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase class-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013344
- InterPro:   IPR000788
- InterPro:   IPR013678 [H]

Pfam domain/function: PF08471 Ribonuc_red_2_N; PF02867 Ribonuc_red_lgC [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 18965; Mature: 18965

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDATPTMGIRTPSGMARRAPRHRQSVTRAFTVGGAYGFIIASLHADGSLADVNLIMAKQ
CCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHEEEEEEECCCCCCCEEEEEEECC
GSTLRGLTETVSSAISTGLAHGVPLVTFVRQFADLRFEPSGHTDDPEIPRATSIIDYVMR
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCEECCCCCCCCCCCCHHHHHHHHHHH
RLALDFLPLDDRTTLGMLTPLERAEIAAEATPAPLSWSDTPGISMSGSFEIPVQVSR
HHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MVDATPTMGIRTPSGMARRAPRHRQSVTRAFTVGGAYGFIIASLHADGSLADVNLIMAKQ
CCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHEEEEEEECCCCCCCEEEEEEECC
GSTLRGLTETVSSAISTGLAHGVPLVTFVRQFADLRFEPSGHTDDPEIPRATSIIDYVMR
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCEECCCCCCCCCCCCHHHHHHHHHHH
RLALDFLPLDDRTTLGMLTPLERAEIAAEATPAPLSWSDTPGISMSGSFEIPVQVSR
HHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953; 11832503 [H]