Click here to switch to the map view.

The map label for this gene is echA6 [H]

Identifier: 158314330

GI number: 158314330

Start: 2976469

End: 2977335

Strand: Direct

Name: echA6 [H]

Synonym: Franean1_2500

Alternate gene names: 158314330

Gene position: 2976469-2977335 (Clockwise)

Preceding gene: 158314329

Following gene: 158314331

Centisome position: 33.14

GC content: 75.43

Gene sequence:

>867_bases
GTGAGATCTGGGAGGGTTGACGCCGTGATAGACGTTGAGCTTCGCGGCGTGTCCGACCCCCGGCCCGCGGCCGGCGAGAG
CCCCCAGCCCGACCAGCCAACCGCCGATCAGAGCACAGAGCAGAGCACCGCGCGCACTGGCGAGCGCCCCGGCGACCCCC
AGATCGCCGTGGTGCGGATCGACCGGCCCGAGCGCCGCAACGCGCTGGACACCGAGCACTGCCTCGGCCTGCGCGCCGGC
ATCGGCCGGGTGCTGGACGCCGGTGTCCGTGCCGTGGTGCTCACCGGCTCCGGGACGAGCTTCTGCGCCGGCGCGGATCT
CGACCAGGTCTACGGCGAGGCCTTCACCGACGCGCTCTACGGAGCGCTGCACGCGCTTACCGGCGCGCCCGTCCCGGTGA
TCGCCGCCATCAACGGGCCGGCCATCGGCGCCGGGCTGCAGCTCGCGCTCGCCGCGGACCTGCGTGTCGCCGTCGAGGAG
GCCTCGTTCGCGGTACCGACGGCGCGGCTCGGCCTGTCGGTGGACCCGTGGACGCTGCGCCGGCTGGCCGAGCTGGCCGG
CGGCGGCGTGGCCCGCGCCATCGTGCTGGGCTGCGAGAGCGTCCCGGCGCGCCGGGCCTTCGAGCTGGGCCTGGTCCAGC
GCGTCGGCGGGCTCGACACCGCCCTCGCCTGGGCCCGGGAGATCGCCGGCCTCGCGCCGCTGACCCTCGCCTACTCCAAG
CGCGCGTTCAACGCGGCCGCCGACCCCGAGGCGGTGCGTCCCGGTGAGGTGATGGCCGCCTACCAGGCATGCTGGACCAG
CGAGGATGCGCAGGAGGGCCGCCGGGCCCGGAGCGAGAAGCGCGCACCGGTCTTCCAGGGCAAGTAG

Upstream 100 bases:

>100_bases
ACGCTGCGCCGGGAGTGCCTGGCCCTGCCCGACCCGGCCCCGCGGACCCTGGTGGATCATGTGCTGGTGGGTGGCTCCGC
GCTACTTCGGGAGCAGCGGG

Downstream 100 bases:

>100_bases
CTGACAGCCGGCCGCGTCAGGCGGGCGAGGAGACGGGGGACGGTGGTCGCGATGGCGAAGTTCGAGACACGCAATCCGGC
GACGGACGAGGTCATCGGGA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MRSGRVDAVIDVELRGVSDPRPAAGESPQPDQPTADQSTEQSTARTGERPGDPQIAVVRIDRPERRNALDTEHCLGLRAG
IGRVLDAGVRAVVLTGSGTSFCAGADLDQVYGEAFTDALYGALHALTGAPVPVIAAINGPAIGAGLQLALAADLRVAVEE
ASFAVPTARLGLSVDPWTLRRLAELAGGGVARAIVLGCESVPARRAFELGLVQRVGGLDTALAWAREIAGLAPLTLAYSK
RAFNAAADPEAVRPGEVMAAYQACWTSEDAQEGRRARSEKRAPVFQGK

Sequences:

>Translated_288_residues
MRSGRVDAVIDVELRGVSDPRPAAGESPQPDQPTADQSTEQSTARTGERPGDPQIAVVRIDRPERRNALDTEHCLGLRAG
IGRVLDAGVRAVVLTGSGTSFCAGADLDQVYGEAFTDALYGALHALTGAPVPVIAAINGPAIGAGLQLALAADLRVAVEE
ASFAVPTARLGLSVDPWTLRRLAELAGGGVARAIVLGCESVPARRAFELGLVQRVGGLDTALAWAREIAGLAPLTLAYSK
RAFNAAADPEAVRPGEVMAAYQACWTSEDAQEGRRARSEKRAPVFQGK
>Mature_288_residues
MRSGRVDAVIDVELRGVSDPRPAAGESPQPDQPTADQSTEQSTARTGERPGDPQIAVVRIDRPERRNALDTEHCLGLRAG
IGRVLDAGVRAVVLTGSGTSFCAGADLDQVYGEAFTDALYGALHALTGAPVPVIAAINGPAIGAGLQLALAADLRVAVEE
ASFAVPTARLGLSVDPWTLRRLAELAGGGVARAIVLGCESVPARRAFELGLVQRVGGLDTALAWAREIAGLAPLTLAYSK
RAFNAAADPEAVRPGEVMAAYQACWTSEDAQEGRRARSEKRAPVFQGK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=29.6442687747036, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI70995211, Length=284, Percent_Identity=26.7605633802817, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI221142681, Length=256, Percent_Identity=33.59375, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787659, Length=250, Percent_Identity=32.4, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788597, Length=248, Percent_Identity=30.6451612903226, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082183, Length=249, Percent_Identity=23.6947791164659, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788682, Length=191, Percent_Identity=33.5078534031414, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=32.9457364341085, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790281, Length=172, Percent_Identity=30.2325581395349, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=257, Percent_Identity=30.7392996108949, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=240, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=221, Percent_Identity=24.8868778280543, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=232, Percent_Identity=28.0172413793103, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=236, Percent_Identity=28.8135593220339, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=172, Percent_Identity=31.9767441860465, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=269, Percent_Identity=24.907063197026, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=195, Percent_Identity=28.7179487179487, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI19920382, Length=216, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24650670, Length=265, Percent_Identity=30.9433962264151, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357171, Length=188, Percent_Identity=31.9148936170213, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 30036; Mature: 30036

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGRVDAVIDVELRGVSDPRPAAGESPQPDQPTADQSTEQSTARTGERPGDPQIAVVRI
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEE
DRPERRNALDTEHCLGLRAGIGRVLDAGVRAVVLTGSGTSFCAGADLDQVYGEAFTDALY
CCCHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHHH
GALHALTGAPVPVIAAINGPAIGAGLQLALAADLRVAVEEASFAVPTARLGLSVDPWTLR
HHHHHHCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHCCCCCCHHHHH
RLAELAGGGVARAIVLGCESVPARRAFELGLVQRVGGLDTALAWAREIAGLAPLTLAYSK
HHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
RAFNAAADPEAVRPGEVMAAYQACWTSEDAQEGRRARSEKRAPVFQGK
HHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRSGRVDAVIDVELRGVSDPRPAAGESPQPDQPTADQSTEQSTARTGERPGDPQIAVVRI
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEE
DRPERRNALDTEHCLGLRAGIGRVLDAGVRAVVLTGSGTSFCAGADLDQVYGEAFTDALY
CCCHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHHH
GALHALTGAPVPVIAAINGPAIGAGLQLALAADLRVAVEEASFAVPTARLGLSVDPWTLR
HHHHHHCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHCCCCCCHHHHH
RLAELAGGGVARAIVLGCESVPARRAFELGLVQRVGGLDTALAWAREIAGLAPLTLAYSK
HHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
RAFNAAADPEAVRPGEVMAAYQACWTSEDAQEGRRARSEKRAPVFQGK
HHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]